SlideShare a Scribd company logo
1 of 4
BioIntel360
https://biointel360.co
m/
Future shifts to in vivo genome editing for a potential treatment strategy
CRISPR has already shown promise in the field of biomedicine, initially by showing improvement in
genome editing in bacteria and then quickly in humans and a wide range of other animals.
While it will take some time before CRISPR becomes more well-known among scientists and ultimately
among the general public, ushering in the CRISPR revolution.
In the last ten years, CRISPR has advanced at an incredible rate, finding use in a variety of industries,
including science, medicine, and agriculture.
It has revolutionized the way we think about genetic engineering and opened the door to a range of
previously unimaginable possibilities. Additionally, it has spurred debate and necessary discussions on
the ethics of genome editing. With the promise of a wide range of applications, CRISPR has quickly
become an invaluable tool in biotechnology and will undoubtedly continue to shape our future.
Professor Doudna and her partner received the 2020 Nobel Prize as a consequence of their work. Base
editors, prime editors, epigenome editors, RNA editors, and other CRISPR proteins have even
undergone several iterations that increase their functionality and therapeutic potential.
It is pretty interesting to speculate about what the future of CRISPR might entail after reviewing its
development over the previous ten years. Where are CRISPR's present applications advancing
medical science? Where will the next phases of the development of CRISPR therapies occur?
Both in vivo and ex vivo uses of CRISPR-based therapeutics are now being sought.
The earliest in vivo applications primarily focused on rare indications, such as hereditary
angioedema, transthyretin amyloidosis, and Leber's congenital amaurosis.
The disease burden is large enough to support a riskier treatment strategy like CRISPR-mediated
gene therapy at this time since the genetic causes are well understood, there is a well-established
clinical development pathway, and the genetic causes are well understood.
Early in vivo CRISPR initiatives also concentrated on disorders that started in organs including the
brain, liver, eye, and blood disorders, and where it is possible to administer the CRISPR machinery.
Thanking
You

More Related Content

Similar to Future shifts to in vivo genome editing for a potential treatment strategy

Biology folding
Biology foldingBiology folding
Biology folding
Sydgold15
 
Altering the Code of Life
Altering the Code of LifeAltering the Code of Life
Altering the Code of Life
April Johnson
 

Similar to Future shifts to in vivo genome editing for a potential treatment strategy (19)

Top 15 Biopharma Research Trends to Watch in 2023.pdf
Top 15 Biopharma Research Trends to Watch in 2023.pdfTop 15 Biopharma Research Trends to Watch in 2023.pdf
Top 15 Biopharma Research Trends to Watch in 2023.pdf
 
Crispr future prospects in public health
Crispr  future prospects in public healthCrispr  future prospects in public health
Crispr future prospects in public health
 
Biology folding
Biology foldingBiology folding
Biology folding
 
Break through in biochemistry biotechnology[616]
Break through in biochemistry biotechnology[616]Break through in biochemistry biotechnology[616]
Break through in biochemistry biotechnology[616]
 
CRISPR: Discovery & Potential Applications
CRISPR: Discovery & Potential ApplicationsCRISPR: Discovery & Potential Applications
CRISPR: Discovery & Potential Applications
 
Impact of advanced technology in biology
Impact of advanced technology in biologyImpact of advanced technology in biology
Impact of advanced technology in biology
 
Crispr
CrisprCrispr
Crispr
 
Crispr cas
Crispr casCrispr cas
Crispr cas
 
CRISPRs
CRISPRsCRISPRs
CRISPRs
 
Crispr Cas9 technique
Crispr Cas9 techniqueCrispr Cas9 technique
Crispr Cas9 technique
 
Next generation sequencing
Next generation sequencingNext generation sequencing
Next generation sequencing
 
The Significance of Lifescience- An In-depth Exploration.pdf
The Significance of Lifescience- An In-depth Exploration.pdfThe Significance of Lifescience- An In-depth Exploration.pdf
The Significance of Lifescience- An In-depth Exploration.pdf
 
CRISPER-Cas9
 CRISPER-Cas9 CRISPER-Cas9
CRISPER-Cas9
 
Genetic engineering of humans
Genetic engineering of humansGenetic engineering of humans
Genetic engineering of humans
 
Altering the Code of Life
Altering the Code of LifeAltering the Code of Life
Altering the Code of Life
 
CRISPR Gene Editing Congress, 25-27 February 2015 in Boston, MA
CRISPR Gene Editing Congress, 25-27 February 2015 in Boston, MACRISPR Gene Editing Congress, 25-27 February 2015 in Boston, MA
CRISPR Gene Editing Congress, 25-27 February 2015 in Boston, MA
 
Designer babies : A Health Wonder Or an Ethical Error
Designer babies : A Health Wonder Or an Ethical ErrorDesigner babies : A Health Wonder Or an Ethical Error
Designer babies : A Health Wonder Or an Ethical Error
 
Crispr technology
Crispr  technologyCrispr  technology
Crispr technology
 
RECOMBINANT DNA TECHNOLOGY AND ITS APPLICATION
RECOMBINANT DNA TECHNOLOGY AND ITS APPLICATIONRECOMBINANT DNA TECHNOLOGY AND ITS APPLICATION
RECOMBINANT DNA TECHNOLOGY AND ITS APPLICATION
 

Recently uploaded

obat pelancar haid di apotik dan harganya
obat pelancar haid di apotik dan harganyaobat pelancar haid di apotik dan harganya
obat pelancar haid di apotik dan harganya
infoobataborsi24
 
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Sampang
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di SampangWA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Sampang
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Sampang
infoobataborsi24
 
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Magetan
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di MagetanWA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Magetan
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Magetan
infoobataborsi24
 

Recently uploaded (20)

Tea Gobec, Kako pluti po morju tehnoloških sprememb, Innovatif.pdf
Tea Gobec, Kako pluti po morju tehnoloških sprememb, Innovatif.pdfTea Gobec, Kako pluti po morju tehnoloških sprememb, Innovatif.pdf
Tea Gobec, Kako pluti po morju tehnoloških sprememb, Innovatif.pdf
 
obat pelancar haid di apotik dan harganya
obat pelancar haid di apotik dan harganyaobat pelancar haid di apotik dan harganya
obat pelancar haid di apotik dan harganya
 
Impacts Of Smart Watch & Wearable Technology On Daily Life
Impacts Of Smart Watch & Wearable Technology On Daily LifeImpacts Of Smart Watch & Wearable Technology On Daily Life
Impacts Of Smart Watch & Wearable Technology On Daily Life
 
Rhys Cater, Precis, The future of media buying with Generative AI.pdf
Rhys Cater, Precis, The future of media buying with Generative AI.pdfRhys Cater, Precis, The future of media buying with Generative AI.pdf
Rhys Cater, Precis, The future of media buying with Generative AI.pdf
 
Engaging Sensory Activities for 5-10 Year Olds
Engaging Sensory Activities for 5-10 Year OldsEngaging Sensory Activities for 5-10 Year Olds
Engaging Sensory Activities for 5-10 Year Olds
 
Killer Packaging | PrintAction
Killer Packaging | PrintActionKiller Packaging | PrintAction
Killer Packaging | PrintAction
 
The Future Normal - DIGGIT - Henry Coutinho-Mason.pdf
The Future Normal - DIGGIT - Henry Coutinho-Mason.pdfThe Future Normal - DIGGIT - Henry Coutinho-Mason.pdf
The Future Normal - DIGGIT - Henry Coutinho-Mason.pdf
 
Best Digital Expert Corporation of India
Best Digital Expert Corporation of IndiaBest Digital Expert Corporation of India
Best Digital Expert Corporation of India
 
Influencer Marekting Trends- Where the creator economy is going in in 2024
Influencer Marekting Trends- Where the creator economy is going in in 2024Influencer Marekting Trends- Where the creator economy is going in in 2024
Influencer Marekting Trends- Where the creator economy is going in in 2024
 
Intelligent Cryptocurrency VIP Digital - Membership Area
Intelligent Cryptocurrency VIP Digital - Membership AreaIntelligent Cryptocurrency VIP Digital - Membership Area
Intelligent Cryptocurrency VIP Digital - Membership Area
 
The seven principles of persuasion by Dr. Robert Cialdini
The seven principles of persuasion by Dr. Robert CialdiniThe seven principles of persuasion by Dr. Robert Cialdini
The seven principles of persuasion by Dr. Robert Cialdini
 
Aiizennxqc Digital Marketing | SEO & SMM
Aiizennxqc Digital Marketing | SEO & SMMAiizennxqc Digital Marketing | SEO & SMM
Aiizennxqc Digital Marketing | SEO & SMM
 
youtube_marketing_partner_vling_service_introduction
youtube_marketing_partner_vling_service_introductionyoutube_marketing_partner_vling_service_introduction
youtube_marketing_partner_vling_service_introduction
 
The BoF Brand Magic Index Volume Two — Preview.pdf
The BoF Brand Magic Index Volume Two — Preview.pdfThe BoF Brand Magic Index Volume Two — Preview.pdf
The BoF Brand Magic Index Volume Two — Preview.pdf
 
Personal Brand Exploration Selk_Ingrid_DMBS_PB1_2024-01.pptx
Personal Brand Exploration Selk_Ingrid_DMBS_PB1_2024-01.pptxPersonal Brand Exploration Selk_Ingrid_DMBS_PB1_2024-01.pptx
Personal Brand Exploration Selk_Ingrid_DMBS_PB1_2024-01.pptx
 
Klaus Schweighofer, Zakaj je digitalizacija odlična priložnost za medije, Sty...
Klaus Schweighofer, Zakaj je digitalizacija odlična priložnost za medije, Sty...Klaus Schweighofer, Zakaj je digitalizacija odlična priložnost za medije, Sty...
Klaus Schweighofer, Zakaj je digitalizacija odlična priložnost za medije, Sty...
 
Key Social Media Marketing Trends for 2024
Key Social Media Marketing Trends for 2024Key Social Media Marketing Trends for 2024
Key Social Media Marketing Trends for 2024
 
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Sampang
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di SampangWA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Sampang
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Sampang
 
Taprank - Boost your Google reviews with personalized NFC cards
Taprank - Boost your Google reviews with personalized NFC cardsTaprank - Boost your Google reviews with personalized NFC cards
Taprank - Boost your Google reviews with personalized NFC cards
 
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Magetan
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di MagetanWA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Magetan
WA | 0821-8888-6412 | Apotik Jual Obat Aborsi Cytotec Asli Di Magetan
 

Future shifts to in vivo genome editing for a potential treatment strategy

  • 2. Future shifts to in vivo genome editing for a potential treatment strategy CRISPR has already shown promise in the field of biomedicine, initially by showing improvement in genome editing in bacteria and then quickly in humans and a wide range of other animals. While it will take some time before CRISPR becomes more well-known among scientists and ultimately among the general public, ushering in the CRISPR revolution. In the last ten years, CRISPR has advanced at an incredible rate, finding use in a variety of industries, including science, medicine, and agriculture. It has revolutionized the way we think about genetic engineering and opened the door to a range of previously unimaginable possibilities. Additionally, it has spurred debate and necessary discussions on the ethics of genome editing. With the promise of a wide range of applications, CRISPR has quickly become an invaluable tool in biotechnology and will undoubtedly continue to shape our future. Professor Doudna and her partner received the 2020 Nobel Prize as a consequence of their work. Base editors, prime editors, epigenome editors, RNA editors, and other CRISPR proteins have even undergone several iterations that increase their functionality and therapeutic potential.
  • 3. It is pretty interesting to speculate about what the future of CRISPR might entail after reviewing its development over the previous ten years. Where are CRISPR's present applications advancing medical science? Where will the next phases of the development of CRISPR therapies occur? Both in vivo and ex vivo uses of CRISPR-based therapeutics are now being sought. The earliest in vivo applications primarily focused on rare indications, such as hereditary angioedema, transthyretin amyloidosis, and Leber's congenital amaurosis. The disease burden is large enough to support a riskier treatment strategy like CRISPR-mediated gene therapy at this time since the genetic causes are well understood, there is a well-established clinical development pathway, and the genetic causes are well understood. Early in vivo CRISPR initiatives also concentrated on disorders that started in organs including the brain, liver, eye, and blood disorders, and where it is possible to administer the CRISPR machinery.