CRISPR has already shown promise in the field of biomedicine, initially by showing improvement in genome editing in bacteria and then quickly in humans and a wide range of other animals. While it will take some time before CRISPR becomes more well-known among scientists and ultimately among the general public, ushering in the CRISPR revolution.
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Future shifts to in vivo genome editing for a potential treatment strategy
1. Future shifts to in vivo genome editing for a
potential treatment strategy
CRISPR has already shown promise in the field of
biomedicine, initially by showing improvement in genome
editing in bacteria and then quickly in humans and a wide
range of other animals. While it will take some time before
CRISPR becomes more well-known among scientists and
ultimately among the general public, ushering in the CRISPR
revolution.
3. Read more- Gene Editing: a hope for Sickle
cell anemia
So far, ex vivo applications have focused on using CRISPR
tools to generate allogeneic, or "off-the-shelf," cell therapies
for hematologic malignancies like non-lymphoma,
Hodgkin's, and multiple myeloma, as well as leukemias and
lymphomas. Ex vivo CRISPR editing presents fewer safety
and delivery challenges than in vivo applications, and
CRISPR editing of cell therapies may be viewed as a safer
alternative to untargeted viral integration-based approaches
that preceded it
4. What to expect in the coming years?
Given CRISPR's advancements to date and enormous
possibilities, the following key trends will make the
technology value in the future.
This cutting-edge CRISPR technique, dubbed "prime
editing," would make it possible to add or remove particular
sequences at genomic regions with reduced side effects.
Prime editors provide more precise editing and targeting
options.