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Sydney Goldfeder
molecular biology
Medicine Student
III Semester
UPB
New 1
Biologists Establish New
Method for Studying RNA's
Regulatory
'Footprint'
Science daily. Jan 8, 2014
Biologists Establish New Method for Studying
RNA's Regulatory
‘Footprint’
Method

 Dubbed: ¨ PIP-seq¨
(sequencing for protein interaction profile )

They thought that
protein-bound segments
of RNA would
be protected
from degradation

comparing their
results to a
control sample,
they concluded
it
wouldn't
serve
to
protect
the
DNA strands
from digestion.
Biologists Establish New Method for
Studying RNA's Regulatory
‘Footprint’
O BSERVATION

The interesting and innovative issue of this research lies in the fact

that they achieve a complete footprint of RNA, previous studies had
only taken a footprint of a unique tissue, additionally, the idea of a
database results efficient, because it allows to trace entire RNA
cycle, orderly. On the other hand, have a full footprint of RNA-RBP
interaction, brings a great benefit in different patterns as the amount
of RNA sequences that appear without be expected, thus
uncovering more mutations and cell affectations
New 2

Express Yourself:

Novel Approach to Study
How Genetic Differences
Affect Gene Expression
Science daily. Jan 9, 2014
Height
Unique Human Genome

Weight
Influence on

 what these
genetic variants are ?
 how they exercise
their impact?

Vulnerability to disease

New approach to understand the ways that individual differences affect certain genes expression
Study duration:

two-and-a-half-year

saccharomyces cerevisiae
O BSERVATION

It

is witty create different ways to understand
human genome, I think that the fact of choosing
single-celled fungus for this research provides a
broad genetic base for elucidate RNA expression,
by the same token, genetic variations and protein
regulation.
Medical
knowing

tility

the right function of human
genome, provides a wide range of
possibilities on science and medicine,
due to the fact that, It is the base for
understand and predict some diseases
and patient conditions, furthermore,
doctors will be able to look forward to
different alternatives in treatments and
prescriptions.
Medical

tility
Medical

tility
Medical

tility
predictive, preventive, and personalized medicine.

Genetics has become the driving force in

medical research and is now poised for
integration into medical practice. The medical
profession now must rise to both the
opportunities and challenges that this wealth
of information presents.
We live in a dancing matrix of viruses; they

dart, rather like bees, from organism to
organism, from plant to insect to mammal to
me and back again, and into the sea, tugging
along pieces of this genome, strings of genes
from that, transplanting grafts of DNA, passing
around heredity as though at a great party.
Lewis Thomas

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Artifacts in Nuclear Medicine with Identifying and resolving artifacts.
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Biology folding

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  • 5. New 1 Biologists Establish New Method for Studying RNA's Regulatory 'Footprint' Science daily. Jan 8, 2014
  • 6. Biologists Establish New Method for Studying RNA's Regulatory ‘Footprint’
  • 7. Method  Dubbed: ¨ PIP-seq¨ (sequencing for protein interaction profile ) They thought that protein-bound segments of RNA would be protected from degradation comparing their results to a control sample, they concluded it wouldn't serve to protect the DNA strands from digestion.
  • 8. Biologists Establish New Method for Studying RNA's Regulatory ‘Footprint’
  • 9. O BSERVATION The interesting and innovative issue of this research lies in the fact that they achieve a complete footprint of RNA, previous studies had only taken a footprint of a unique tissue, additionally, the idea of a database results efficient, because it allows to trace entire RNA cycle, orderly. On the other hand, have a full footprint of RNA-RBP interaction, brings a great benefit in different patterns as the amount of RNA sequences that appear without be expected, thus uncovering more mutations and cell affectations
  • 10. New 2 Express Yourself: Novel Approach to Study How Genetic Differences Affect Gene Expression Science daily. Jan 9, 2014
  • 11. Height Unique Human Genome Weight Influence on  what these genetic variants are ?  how they exercise their impact? Vulnerability to disease New approach to understand the ways that individual differences affect certain genes expression
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  • 14. O BSERVATION It is witty create different ways to understand human genome, I think that the fact of choosing single-celled fungus for this research provides a broad genetic base for elucidate RNA expression, by the same token, genetic variations and protein regulation.
  • 15. Medical knowing tility the right function of human genome, provides a wide range of possibilities on science and medicine, due to the fact that, It is the base for understand and predict some diseases and patient conditions, furthermore, doctors will be able to look forward to different alternatives in treatments and prescriptions.
  • 18. Medical tility predictive, preventive, and personalized medicine. Genetics has become the driving force in medical research and is now poised for integration into medical practice. The medical profession now must rise to both the opportunities and challenges that this wealth of information presents.
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  • 20. We live in a dancing matrix of viruses; they dart, rather like bees, from organism to organism, from plant to insect to mammal to me and back again, and into the sea, tugging along pieces of this genome, strings of genes from that, transplanting grafts of DNA, passing around heredity as though at a great party. Lewis Thomas