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Corona Virus Biography
- 1. By: Aseel Abuhamdah CORONA VIRUS By: Aseel Abuhamda Last Update: March 20, 2020
- 3. CoronavirusCoV:familyof viruseswithcrown-likespikesonsurface SARS:SevereAcuteRespiratorySyndrome-relatedcoronavirus MERS:MiddleEastRespiratorySyndrome-relatedcoronavirus nCoVID-19:NovelCoronaVIrusDisease2019 outbreak:suddenincreaseinoccurrencesof disease epidemic:rapidspreadof diseaseincertaingeographicalarea pandemic:spreadof infectionglobally SARS-CoV:virusresponsiblefor2002-2003pandemic SARS-CoV-2: asecondvirusof SARStyperesponsiblefor2019-2020pandemic MINI-GLOSSARY 3
- 4. HISTORY 2003 2012 Possible Host: Camels 2500+ Infections 886 Deaths Spread to 27 countries 2019 SARS-CoV-2 First Reported in China SARS-CoV First Reported in China MERS-CoV First Reported in KSA Possible Host: Civet Cats 8000+ Infections 774 Deaths Spread to 26 countries Possible Host: Pangolins 300,000+ Infections 12,000+ Deaths Spread to 37 countries 4
- 6. How was the virus source known? Sample (Throat Swab or Nasopharynx) of infected patient was taken Convert RNA to DNA (reverse transcription) as majority of test kits are designed for DNA Genetic Sequencing was done to find the genome The result was compared with genomes in a library 70% of sequence matched with bats genome (SARS strain) . The rest 30% is believed to have been mutated Another hypothesis: “virus DNA is fusion of two DNA’s that could have occurred in bat or snake” Bats being sold in Indonesian Market https://www.bbc.com/news/science-environment-51496830 6
- 7. Tests to find if patient infected or not 7 ◦ Virus in patient can be found by ◦ Test kits e.g “RT PCR” by Singapore. Nose or throat swab are required https://www.youtube.com/watch?v=tgyzdgf66e M ◦ Chest scan for lungs ◦ Antibody test by taking blood sample
- 8. Interested to see how genetic sequence is done and what a genetic sequence looks like? Genetic Sequence Process https://www.youtube.com/watch?v=Jvy6C5c9xT w ◦ Genetic Sequence of SARS-CoV-2 https://www.ncbi.nlm.nih.gov/nuccore/MN9089 47 8
- 9. SYMPTOMS 9
- 10. How to Protect Yourself? Source: https://www.bbc.com/news/health- 51048366 10
- 11. Response of some Countries to SARS-CoV-2 ◦ UK ◦ No stringent measures have been taken, in order to provide “herd immunity” if second wave of virus hits ◦ Prime Minister: “Many loved ones will die” ◦ China ◦ Built a hospital in 10 days ◦ National Lockdown imposed ◦ Found genetic sequence of virus within 3-4 weeks ◦ Controlled infection within almost 4 months ◦ Sent 2 million Protective Personal Equipment to Italy o Australia o Activated emergency plan before WHO announced it as pandemic and before G7 nations o Immediately Released emergency funding and tax breaks 11
- 12. Response of some Countries to SARS-CoV-2 ◦ Germany, France, Spain ◦ Germany: Suspended outdoor activities, closed borders with neighboring countries, ◦ France & Spain: limited movement for doctor and food only are permitted ◦ Iran ◦ Initially denied the risk ◦ Weak health system ◦ Slow movement of officials played a higher risk in increasing number of infected people + mortality rate o Italy o The outrageous number of infected people and fatalities was a wake-up-call for national lockdown and airport suspension o Medical resources are no longer enough o Medical staff are prioritizing treatments for younger patients 12
- 13. Response of some Countries to SARS-CoV-2 ◦ Singapore ◦ 200+ cases, no deaths ◦ Sent 10,000 kits to China ◦ Excellent health system ◦ Strict virus testing ◦ Tracing and containment programs ◦ Small population ◦ Citizens who are largely accepting of what the government orders to them to do. ◦ Jordan ◦ National curfew has been imposed ◦ Airport has been suspended, all incoming passengers were taken to 4* and 5* hotels ◦ Grocery, Bread, Water, Fuel, Medicines are delivered to citizen’s doorstep ◦ Paid work leave granted amid curfew o USA o Trump declared a national emergency unleashing billions of dollars o National curfew imposed in several states 13
Editor's Notes
- How can the virus circulate other than feeding the predecessor?