1. HYPOPITUITARISM
Period:1 Ingrid Natali, Margarita Chen, Vanessa Mendez

2. What is this?
 Hypopituitarism is a rare disorder where
there is a loss of function in the pituitary
and the failure to secrete hormones that
affect many of the body's functions.
 Patients diagnosed with hypopituitarism
may be deficient in one or several
hormones or have complete pituitary
failure.

3. Where is this?
 The pituitary gland is located at the base of the
brain.
 In hypopituitarism, the pituitary gland is
effected by something and may be deficient in
one single hormone, several hormones, or
have complete pituitary failure.

4. Causes of the disorder
 Congenital
 Tumor
 Inflammation
 Infection
 Head injuries
 Lesions
 Surgery
 Tuberculosis
 Radiographic therapy

5. ACTH – adrenocorticotropic hormone
ADH – anti-diuretic hormone, or
vasopressin
FSH – follicle-stimulating hormone
GH – growth hormone
LH – luteinizing hormone
PRL – prolactin
TSH – thyroid-stimulating hormone

6. Who and when?
 Can affect both males and
females.
 Can occur at any time in life.
 Can be congenital .

7. Hypopituitarism in children
 Hypopituitarism may be
congenital (a condition present at
birth) and caused by:
 Birth trauma
 Genetic (inherited) disorders
 Central nervous system defects
 Defective, underdeveloped, or absent
pituitary gland

8. Hypopituitarism is adults
 Hypopituitarism can also be
acquired (a condition that develops
later in life) and may be caused by:
 Radiation to the head
 Tumors in the brain
 Other disorders, such as tuberculosis or
sarcoidosis which infiltrate the gland, can
result in a reduction in function.

9. Symptoms
 Fatigue
 Weight loss
 Decreased sex drive
 Decreased appetite
 Facial puffiness
 Anemia
 Infertility
 Women problems (hot flashes and periods)
 Decreased facial hair

10. A
B
A- Hair loss
B- Addison’s disease
C- Tumor by the pituitary gland
C

11. Diagnosis
 Blood test
 Stimulation or dynamic blood testing
 Brain imaging
 Vision tests
 X-rays

12. Treatments
 Differs depending on:
-age
-sex
-severity of the deficiency
-number of hormones involved
-underlying cause of the hypopituitarism
 Immediate hormone replacement to replace
the deficient hormone.
 Patient education

13. Prognosis/Prevention
 Patients can lead a normal life
 Hypopituitarism is permanent so it requires a
lifelong treatment
 Patients will have to alter their lives depending
on the primary cause of the disorder
 There is no known prevention except for the
prevention of damage to the
pituitary/hypothalamic area from injury.

14. Work Cited
1. Hypopituitarism. (2010, October
2).http://www.cnn.com/HEALTH/library/hypopituitarism/DS00479
.html. Retrieved February 26, 2012, from
http://www.cnn.com/HEALTH/library/hypopituitarism/DS00479.ht
ml
2. Eckman, A. S. (2009, November 25). Hypopituitarism. MedLine
Plus. Retrieved February 26, 2012, from
http://www.nlm.nih.gov/medlineplus/ency/article/000343.htm
3. Steelmen, J. W. (2010, July 14). Pediatric n
Hypopituitarism. MedScape Reference. Retrieved February 26, 2012,
from http://emedicine.medscape.com/article/922410-
overview#aw2aab6b2b4

15. 4. Hypopituitarism - MayoClinic.com. (n.d.). Mayo Clinic. Retrieved February
26, 2012, from http://www.mayoclinic.com/health/hypopituitarism/DS00479
5. Hypopituitarism - PubMed Health. (n.d.). National Center for Biotechnology
Information. Retrieved February 26, 2012, from
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001383/
6. Medscape: Medscape Access. (n.d.). Medscape: Medscape Access.
Retrieved February 26, 2012, from
http://emedicine.medscape.com/article/122287-overview
7.Vitiligo — Medlibes: Online Medical Library. (n.d.). Medlibes - Online
Medical Library. Retrieved February 26, 2012, from
http://medlibes.com/entry/vitiligo
8. WEB BASED LEARNING IN. (n.d.). Faculty of Life Sciences ELP: e-
Learning Projects. Retrieved February 26, 2012, from
http://www.elp.manchester.ac.uk/pub_projects/2002/MNBY9APB/THEPITU
ITARYHORMONES.htm