Presented by Phil Toye at the 9th Symposium on Diseases in Asian Aquaculture, Ho Chi Minh City, Vietnam, 24-28 November 2014

1. Approaches in livestock animal health
research and management
9th Symposium on Diseases in Asian Aquaculture,
Ho Chi Minh City, Vietnam, 24-28 November 2014
Phil Toye, International Livestock Research Institute, Nairobi

2. Dryland Cereals
Grain Legumes
Livestock and Fish
Maize
Rice
Roots, Tubers and Bananas
Wheat
Climate Change, Agriculture and Food Security
Forests, Trees and Agroforestry
Water, Land and Ecosystems
Humidtropics
Aquatic Agricultural Systems
Dryland Systems
Policies, Institutions, and Markets
Agriculture for Nutrition and Health
Genebanks

3. Dryland Cereals
Grain Legumes
Livestock and Fish
Maize
Rice
Roots, Tubers and Bananas
Wheat
Climate Change, Agriculture and Food Security
Forests, Trees and Agroforestry
Water, Land and Ecosystems
Humidtropics
Aquatic Agricultural Systems
Dryland Systems
Policies, Institutions, and Markets
Agriculture for Nutrition and Health
Genebanks
More milk, meat, and fish by
and for the poor
Led by ILRI with CIAT, ICARDA and
WorldFish

4. Working in 9 target value chains

5. L & F – research structure
Technology Platforms
Animal health
Genetics
Feed & forages
Systems Analysis
for Sustainability
• Social sciences
• Gender
• Targeting
• Environment
Value Chain
Transformation &
Scaling
• Integrating for impact in
focus value chains
• Innovation
• Targeting
• Partnerships
• Capacity development
• Communication

6. Animal Health Flagship
Assessment
Population
health
Vaccines &
diagnostics
Delivery

7. Vaccine Development Stages
Preclinical
Evidence of
immunity
Mechanism of
immunity
In vitro correlate
Antigen i/d
Delivery system
Stage 2
Field trials
Stage 3
Commercial
manufacture
Registration
Distribution
Stage 1
Safety / Dosage
Immunogenicity
Efficacy
- East Coast Fever
- Contagious bovine
pleuropneumonia
- African Swine Fever
ECF
- ECF (p67)
- Peste des petits
ruminants
ECF

8. East Coast fever
• Tick borne protozoan, >90% mortality
• Heavy use of acaricides
• ITM – infection and treatment method
• Sub unit vaccines
• - sporozoite
• - schizont

9. Clinical
Point-of-care
Laboratory
Market
Food safety
Trade
Research Epidemiological
Uses of diagnostic assays

10. Diagnostic Assay Development Stages
Preclinical
Identification of
biologicals
Selection /
development of
platform
Collection of
samples
Stage 2
Field validation
Stage 3
Commercial
manufacture
Registration
Distribution
Stage 1
Experimental
validation
CBPP
ASF
Cysticercosis
PPR
- (Cysticercosis)
Tick borne
diseases

11. Thank you
ILRI
Better lives through livestock