4. INTRODUCTION
Translation is protein
synthesis guided by a mold
mRNA.
Protein synthesis involves the
interaction of three types of
RNA molecules: mRNA, tRNA,
rRNA and consists of 3 stages:
initiation, elongation and
termination.
5. Repair system discovered
in algae, new tools of
biotechnology.
Novel 'repair system' discovered in algae may
yield new tools for biotechnology.
Boyce Thompson Institute.
July 29, 2016.
6. Repair system discovered in algae, new
tools of biotechnology.
Algae C. reinhardtii can break the
interrumping sequence from a
protein. It removes the insertions
in proteins that alter their
function.
7. Repair system discovered in algae, new
tools of biotechnology.
Short version
has the
ability to cut
RNA.
Can be
purified
starting from
C. reinhardtii
chloroplasts.
RB47:
Protein
8. Repair system discovered in algae, new
tools of biotechnology.
The most important
finding: A long protein
RB47 without function may
become short, by mixing
them with the algae
chloroplasts on light.
9. Repair system discovered in algae, new
tools of biotechnology.
STUDENT’S
OBSERVATION
This discovery represents a
breakthrough for the pharmaceutical
industry because by this protein can
develop drugs with ability to
activate or inhibit the function of
virus or bacteria with specific
proteins , which could be important
for future cancer treatment.
10. Stem cells of worms, humans more
similar than expected.
Stem cells of worms, humans more similar than
expected
Max Delbrück Center for Molecular Medicine
in the Helmholtz Association
August 9, 2016
11. Stem cells of worms, humans more
similar than expected.
The transient form of genetic
information and RNA are processed in a
similar manner in humans and in worms
12. Stem cells of worms, humans more
similar than expected.
In worms are identified
numerous alternative
exons responsible for
stem cell-specific
protein variants.
CELF: protein
counteracts
MBNL by
stimulating the
production of
these variants.
MBNL:
suppresses the
production of
stem cell-
specific protein
variants
13. Stem cells of worms, humans more
similar than expected.
Was identified splicing
processes that operate only in
the stem cells of the worms.
14. Stem cells of worms, humans more
similar than expected.
This is so interesting because planarian
has a remarkable ability to regenerate any
part of the lost body through its many
stem cells, and through this research
achievement demonstrate that they have
similarities in the processes of RNA with
humans, and maybe so can perform more
complex experiments led to the ability of
regeneration applied to humans
STUDENT’S
OBSERVATION
15. Medical utility
The new about the algae C.
reinhardtii has a great importance
in the field of pharmacology
therefore has significant medical
utility, if they were to develop
drugs based on the mechanism of
action of this protein (RB47), it
could activate and deactivate
proteins by the addition or removal
of additional sequences.
16. Medical utility
The new about the stem cells in
worms affect the medical advances for
future generations, because as this
research achievement demonstrate
the similarity between stem cells
human and worm, it can develop
processes by which stem cells
eachother humans have regenerative
capabilities.
17. Medical utility
Both studies have important for the field of modern medicine advances,
because of his discoveries are so novel, useful and never mentioned
above.
18. Medical utility
The research done deal
intron sequences, which can
lead to infer that there
multiple research in this field
to make that may be useful
in the field of the repair
proteins and therefore
production of drugs
19. BIBLIOGRAPHY
Boyce Thompson Institute. (2016, July 29). Novel 'repair system' discovered in algae may
yield new tools for biotechnology: Chloroplasts can cut an interrupting insertion from a
protein, but only in the light. ScienceDaily. Retrieved September 4, 2016 from
www.sciencedaily.com/releases/2016/07/160729092528.htm
Max Delbrück Center for Molecular Medicine in the Helmholtz Association. (2016, August
9). Stem cells of worms, humans more similar than expected: The same regulatory
mechanisms are active in the stem cells of flatworms and humans.ScienceDaily.
Retrieved September 4, 2016
Martínez Sánchez , Lina María; Vargas Grisales, Natalia; Cardona Mejía, Laura; Osorio
Ospina, Felipe; Ramírez Pulgarin , Sergio. (29 de Julio de 2015). Biología Molecular. En
Biología molecular (octava edición) (pág. 141). Medellín: Editorial Universidad Pontificia
