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Antigens & Antibodies 
Medical Interventions
Antigen 
• An antigen is any substance that causes 
your immune system to produce antibodies 
against it. 
• An antigen may be a foreign substance from 
the environment such as chemicals, 
bacteria, viruses, or pollen. (Exogenous) 
• An antigen may also be formed within the 
body, as with bacterial toxins or tissue cells. 
(Endogenous) 
http://www.nlm.nih.gov/medlineplus/ency/article/002224.htm
• Antigens are macromolecules that elicit an 
immune response in the body. Antigens can 
be 
• Proteins 
• Polysaccharides 
• Conjugates of proteins and polysaccharides 
• Conjugates of lipids with 
– proteins (lipoproteins) 
– polysaccharides (glycolipids). 
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/AntigenPresentation.html
http://faculty.matcmadison.edu/mljensen/bloodbank/lectures/blood_bank_antigens_and_antibodi.htm
Blood Cell Antigens 
http://www.netwellness.org/healthtopics/blood/bloodtypes.cfm 
http://rhincompatibility.wordpress.com/understanding-the-rh-blood-group- 
system/
Antibodies 
• An antibody is a protein produced by the body's 
immune system when it detects harmful substances, 
called antigens. Examples of antigens include 
microorganisms (such as bacteria, fungi, parasites, and 
viruses) and chemicals. 
• Antibodies are also produced when the immune 
system mistakenly considers healthy tissue a harmful 
substance. (Autoimmune disorders) 
• Each type of antibody is unique and defends the body 
against one specific type of antigen. 
http://www.nlm.nih.gov/medlineplus/ency/article/002223.htm
Antibody Model 
http://www.michigananimalhospital.com/page/452419682
Antibodies 
http://www.ortho-wire.com/en/
Antigen-Antibody Interaction 
http://www.emc.maricopa.edu/faculty/farabee/biobk/biobookimmun.html
Agglutination 
http://medical-dictionary. 
thefreedictionary.com/agglutination 
http://www.biologymad.com/master.html?http://www.biologym 
ad.com/immunology/immunology.htm

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Antigens & antibodies Intro

Editor's Notes

  1. Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to polypeptide side-chains. Glycoproteins are often important integral membrane proteins, where they play a role in cell–cell interactions.