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2
For the last few months, the world has been consumed with a minute virus-
COVID 19, roughly 65-125 nm in diameter- that has been infecting and killing
the human population.
It is important to understand the transmission and the effect of COVID-19,
which has made it a pandemic across the world.
3
Viruses have lived on the earth mutating and adopting for billions of years.
What is the nature of virus ?
4
they neither dead nor alive, they are active inside a living thing,
Virus is powerless in the open air but rise again in an another host.
Goal
Of the
virus
(Processed)
(Replicate
& Spread)
COVID-19
5
Smallpox AIDS Polio
Virus
disease
Now we are facing a new disease
6
What is COVID-19 ?
COVID-19 belongs to the corona virus family. Which also include –
Spreads through the air on moisture droplets or on surfaces.
This virus affects the human through the respiratory tract.
SARS ( severe Acute Respiratory Syndrome )
MERS (Middle East Respiratory Syndrome ).
7
The primary symptoms of this infections are-
Fever Dizziness
Smell &
Taste
Dry Cough Headache
Pneumonia
Breathlessness
How Does Coronavirus Affect the Lungs –
Enters
8
Eventually settles in the air sacs or alveoli, inside our lungs.
There are millions of tiny air sacs or alveoli present in our lungs.
9
10
The virus “ hijacks “ the cells in the alveoli. In that cell they enter and use the cell
Replication machinery and begins making copies of itself,
it spreads and attack the neighboring cells until the host cell dies.
COVID-19
Unsuspecting Cell that has
Right receptor
11
When the virus enters in the alveoli-
It promotes an immune response in the body inside the alveoli.
12
Macrophage
Attacks
13
Sometime it can defeats the virus.
If our body needs more help, cytokines protein recruit more
immune cell.
14
neutrophiles
All these response of immune cells occurs in the form of inflammation.
15
But the neutrophiles, more than attacking the virus, also injured the alveoli
and ultimately breaking down its walls.
16
The walls of the alveolus is also damaged by the COVID-19 virus. Now as the
air- sacs are damaged , two problem arises –
The debris from the damage of the wall which is plasma protein, accumulates
on the alveolus wall and thickens the lining of alveolus. As the walls gets
thicken, the transfer of oxygen to the red blood cells is become impaired .
and the body is running lack of oxygen, which cause difficulty in breathing
and ultimately leads to
Dry Cough
17
And the 2nd problem arises due to the damage of the alveolus wall is, fluid rushes
from the blood vessel into the alveolus, filling it up gradually-
Pneumonia
Its much harder to Breath now….
Leads to
18
As such some patients may requires ventilators
to aid breathing.
Over reaction of immune-cell
Though the body immune system tried to
destroy the virus by over production of
cytokine immune cell, but in severe cases
COVID-19
Uncontrolled Inflammation Cytokine - Strom
Leads to
Results in
19
Too many alveoli collapse. Now in this
situation, immune cells harms the body more
than it helps. And this is how COVID-19 turns
your own immune systems Against You.
The attack from the virus
Immune system’s
explosive response
Makes coronavirus
So DEADLY
As the damage of lungs increases
potentially, resulting in respiratory
failure and all these can leads to -
Acute Respiratory Distress Syndrome
(ARDS)
DEAD
20
COVID-19 doesn't just affect the Lungs.
 Heart
 Kidneys
 Intestinal tract
 liver
Typically, older patients and the people who have
underlying medical condition such as diabetes, heart
disease, cancer, hypertension are those who are at
greater risk to recover from COVID-19, because of
their Weaker Immune Systems.
There is no specific treatments for coronavirus and investigation is
under process through out the World.
Also vaccines are currently in developed.
Symptoms can be treated through Supportive Care.
21
What can you do to protect yourself from COVID-19 ?
Regular hand washing Use mask to cover your
nose, mouth and hair
Avoid anyone coughing
/ sneezing
Avoid Animals Cook Thoroughly Cover your mouth and
nose while Coughing or
Sneezing !!!
22
The travel & spreading of the
virus stops & we can return back
to our normal daily life.
So that we can fight against this devastating pandemic.
23

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How covid-19 affects the lungs

  • 1.
  • 2. 2 For the last few months, the world has been consumed with a minute virus- COVID 19, roughly 65-125 nm in diameter- that has been infecting and killing the human population. It is important to understand the transmission and the effect of COVID-19, which has made it a pandemic across the world.
  • 3. 3 Viruses have lived on the earth mutating and adopting for billions of years. What is the nature of virus ?
  • 4. 4 they neither dead nor alive, they are active inside a living thing, Virus is powerless in the open air but rise again in an another host. Goal Of the virus (Processed) (Replicate & Spread) COVID-19
  • 5. 5 Smallpox AIDS Polio Virus disease Now we are facing a new disease
  • 6. 6 What is COVID-19 ? COVID-19 belongs to the corona virus family. Which also include – Spreads through the air on moisture droplets or on surfaces. This virus affects the human through the respiratory tract. SARS ( severe Acute Respiratory Syndrome ) MERS (Middle East Respiratory Syndrome ).
  • 7. 7 The primary symptoms of this infections are- Fever Dizziness Smell & Taste Dry Cough Headache Pneumonia Breathlessness How Does Coronavirus Affect the Lungs – Enters
  • 8. 8 Eventually settles in the air sacs or alveoli, inside our lungs. There are millions of tiny air sacs or alveoli present in our lungs.
  • 9. 9
  • 10. 10 The virus “ hijacks “ the cells in the alveoli. In that cell they enter and use the cell Replication machinery and begins making copies of itself, it spreads and attack the neighboring cells until the host cell dies. COVID-19 Unsuspecting Cell that has Right receptor
  • 11. 11 When the virus enters in the alveoli- It promotes an immune response in the body inside the alveoli.
  • 13. 13 Sometime it can defeats the virus. If our body needs more help, cytokines protein recruit more immune cell.
  • 14. 14 neutrophiles All these response of immune cells occurs in the form of inflammation.
  • 15. 15 But the neutrophiles, more than attacking the virus, also injured the alveoli and ultimately breaking down its walls.
  • 16. 16 The walls of the alveolus is also damaged by the COVID-19 virus. Now as the air- sacs are damaged , two problem arises – The debris from the damage of the wall which is plasma protein, accumulates on the alveolus wall and thickens the lining of alveolus. As the walls gets thicken, the transfer of oxygen to the red blood cells is become impaired . and the body is running lack of oxygen, which cause difficulty in breathing and ultimately leads to Dry Cough
  • 17. 17 And the 2nd problem arises due to the damage of the alveolus wall is, fluid rushes from the blood vessel into the alveolus, filling it up gradually- Pneumonia Its much harder to Breath now…. Leads to
  • 18. 18 As such some patients may requires ventilators to aid breathing. Over reaction of immune-cell Though the body immune system tried to destroy the virus by over production of cytokine immune cell, but in severe cases COVID-19 Uncontrolled Inflammation Cytokine - Strom Leads to Results in
  • 19. 19 Too many alveoli collapse. Now in this situation, immune cells harms the body more than it helps. And this is how COVID-19 turns your own immune systems Against You. The attack from the virus Immune system’s explosive response Makes coronavirus So DEADLY As the damage of lungs increases potentially, resulting in respiratory failure and all these can leads to - Acute Respiratory Distress Syndrome (ARDS) DEAD
  • 20. 20 COVID-19 doesn't just affect the Lungs.  Heart  Kidneys  Intestinal tract  liver Typically, older patients and the people who have underlying medical condition such as diabetes, heart disease, cancer, hypertension are those who are at greater risk to recover from COVID-19, because of their Weaker Immune Systems. There is no specific treatments for coronavirus and investigation is under process through out the World. Also vaccines are currently in developed. Symptoms can be treated through Supportive Care.
  • 21. 21 What can you do to protect yourself from COVID-19 ? Regular hand washing Use mask to cover your nose, mouth and hair Avoid anyone coughing / sneezing Avoid Animals Cook Thoroughly Cover your mouth and nose while Coughing or Sneezing !!!
  • 22. 22 The travel & spreading of the virus stops & we can return back to our normal daily life. So that we can fight against this devastating pandemic.
  • 23. 23