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+           F               F+
            O2

        F         F                                F F
F                      F           F F F            F
            F              F               F   F               F
                               F                         F F
    F           F ??
( F)
                      F                F       F                         F
                          F                                      F
F         F       F                        F
                               F                                     F

    F F                                            F
              F               F F                            F
F
    **                             F
                      F   F                            F F
                  F F ***
                                                                             Glucose
7.3 kcal/mol




ATP = adenosinetriphosphate
NADH        (NICOTINAMINE ADENINE DINUCLEOTIDE)

  F
NAD+ + H+ + 2e-              NADH
                       F
       F NADH          F     F ATP
     B5           (niacin)     F
( F)
          F         F FF               F                           F
 F          F F F ATP
   F F F ATP F               F             F       F       F
        F F     ATP                            F
      F       F
                  F      F       F F                   F       F
F ????
F
F


         F                       F
(high energy)      O2   (low energy)


C H O (N     S)
F  F     ,     ,        F   ,   F      F
Cytosol
            F




                         +




          Mitochondria
F




Fructose   Glucose   Galactose
MITOCHONDIA
Glucose


GLYCOLYSIS
             F 2 ATP


              2 PGAL




              F 4 ATP
             2 NADH


             2 Pyruvate
GLYCOLYSIS
        2ATP   2ADP + 2Pi       4ADP + 2Pi   4ATP

Glucose              2 PGAL                    2 pyruvic acid
 (6C)                  (3C)                          (3C)
                                 2NAD+       2NADH




                            F    6                   F   3

   2 Pyruvic acid + 2 ATP + 2 NADH
ACETYL COA

                       2 CoA        2 CO2

      2 pyruvic acid                        2 Acetyl CoA
           (3C)                                (2C)
                        2NAD+       2NADH


             F    3             F           CO2 F
  F    2          acetyl CoA            F

           2 Acetyl CoA + 2 NADH + 2 CO2
KREB'S CYCLE             NADH




                                                               CoA


                       Oxaloacetic(4C)




               NADH
                                                                             NADH

                                                          Ketoglutaric(5C)

Acetyl CoA 1            Malonic (4C)

  F 3 NADH
    1 FADH2                              Succinic (4C)



    1 ATP             FADH2
                                                    ATP    NADH
KREB’S CYCLE
            1       F Acetyl CoA   2
  F    F2       F

                    6 NADH
                    2 FADH2
                      2 ATP
                      4 CO2
ELECTRON TRANSPORT CHAIN
               F               NADH          FADH2
   F                       F
   F F                          F
                       F      H+              F                    F
                                                                            H2 O
 ATP                  ATP synthase


NADH               FADH2       Cyt.B         Cyt.C   Cyt.A             O2




         ATP                           ATP                   ATP
ELECTRON TRANSPORT CHAIN
NADH     FADH2                                   F
                 2NADH        F               6ATP
                 2NADH                    F   6ATP
                                                         34ATP
             F   6NADH                F       18ATP
                 2FADH2           F           4ATP

   ATP                    F
                 2ATP
             F   2ATP                            38ATP

         F       34ATP
(   )
                                 2ATP

                     2NADH       6ATP


                     2NADH       6ATP
        Acetyl CoA




                                    2ATP

               F        2FADH2      4ATP

                        6NADH       18ATP



                        36ATP

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การสลายสารอาหารโดยใช้ออกซิเจน

  • 1.
  • 2. + F F+ O2 F F F F F F F F F F F F F F F F F F F F ??
  • 3. ( F) F F F F F F F F F F F F F F F F F F F F ** F F F F F F F *** Glucose
  • 4. 7.3 kcal/mol ATP = adenosinetriphosphate
  • 5. NADH (NICOTINAMINE ADENINE DINUCLEOTIDE) F NAD+ + H+ + 2e- NADH F F NADH F F ATP B5 (niacin) F
  • 6. ( F) F F FF F F F F F F ATP F F F ATP F F F F F F F ATP F F F F F F F F F F ????
  • 7. F
  • 8. F F F (high energy) O2 (low energy) C H O (N S) F F , , F , F F
  • 9. Cytosol F + Mitochondria
  • 10. F Fructose Glucose Galactose
  • 12. Glucose GLYCOLYSIS F 2 ATP 2 PGAL F 4 ATP 2 NADH 2 Pyruvate
  • 13. GLYCOLYSIS 2ATP 2ADP + 2Pi 4ADP + 2Pi 4ATP Glucose 2 PGAL 2 pyruvic acid (6C) (3C) (3C) 2NAD+ 2NADH F 6 F 3 2 Pyruvic acid + 2 ATP + 2 NADH
  • 14. ACETYL COA 2 CoA 2 CO2 2 pyruvic acid 2 Acetyl CoA (3C) (2C) 2NAD+ 2NADH F 3 F CO2 F F 2 acetyl CoA F 2 Acetyl CoA + 2 NADH + 2 CO2
  • 15. KREB'S CYCLE NADH CoA Oxaloacetic(4C) NADH NADH Ketoglutaric(5C) Acetyl CoA 1 Malonic (4C) F 3 NADH 1 FADH2 Succinic (4C) 1 ATP FADH2 ATP NADH
  • 16. KREB’S CYCLE 1 F Acetyl CoA 2 F F2 F 6 NADH 2 FADH2 2 ATP 4 CO2
  • 17. ELECTRON TRANSPORT CHAIN F NADH FADH2 F F F F F F H+ F F H2 O ATP ATP synthase NADH FADH2 Cyt.B Cyt.C Cyt.A O2 ATP ATP ATP
  • 18. ELECTRON TRANSPORT CHAIN NADH FADH2 F 2NADH F 6ATP 2NADH F 6ATP 34ATP F 6NADH F 18ATP 2FADH2 F 4ATP ATP F 2ATP F 2ATP 38ATP F 34ATP
  • 19. ( ) 2ATP 2NADH 6ATP 2NADH 6ATP Acetyl CoA 2ATP F 2FADH2 4ATP 6NADH 18ATP 36ATP