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Writing a compelling grant
to fund your research
Scott McClelland
Craig Cohen
Richard Chaisson
6th December 2013
2nd Bi-Annual CFAR SSA Meeting
Cape Town, South Africa
Overview
• Introduction
– Components of a research grant
– Review criteria and the review process

• Novel hypotheses and innovation
• Assembling your team
• Tackling the approach
Key Components of Research
Proposal
• Title
• Budget &
Justification
• Abstract & Key
Personnel
• Research Plan
Review Criteria
• Overall Impact
• Significance: How will scientific
knowledge be advanced?
• Approach: Are the framework, design,
methods, and analyses adequately
developed, well integrated, well
reasoned, and appropriate?
Review Criteria
• Innovation: Is the project original or
does it provide a necessary step for
advancing the field?
• Investigators: Adequate training/
expertise of investigative team?
• Environment: Will the research (and
training) environment contribute to the
probability of success?
Cartoon Credit: Chris O’Hara from Googledocs.com
Consider your Audience(s)

Two to three primary reviewers
Consider your Audience(s)

5 to 15 additional reviewers
Research Plan
• Hypotheses and Specific Aims
• Research Strategy
– Significance
– Innovation
– Approach

• Human Subjects
Research Plan
• Hypotheses and Specific Aims
• Research Strategy
– Significance
– Innovation
– Approach

• Human Subjects
Getting Started

“Experiencing a Writers Block” www.torito.nl
Start with a Thorough Review of
the Relevant Literature
Preparing to Write
• Comprehensive literature search
• Search references of retrieved articles
• Read carefully
– Consider taking notes or highlighting

• Talk with colleagues
• Talk with grant contact person
Image Credit: Funzug.com

Inadequate Preparation Prior to Writing – A Fatal Flaw
Hypotheses and Specific Aims
• States the research questions (hypotheses)
and how they will be addressed (aims)
Milliondollardatsun.com

Burning Question
Big, Big Aim
Approach
Approach

istockphoto.com
Hypotheses & Specific Aims
• Start with a brief narrative describing
long-term goals
• Followed by numbered list of aims
– Most successful larger applications have 24 aims (3 is typical)
– Multiple aims should be clearly related

• Should fit on one page
• State hypotheses clearly
Lack of clear hypothesis – A fatal flaw
Sample Structure of Aims Page
Innovation

• Be careful with innovation.
– It is enough to show how the work is new
and unique and how it will add significantly
to what's known.
Writing a Compelling Grant to Fund Your Research

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Writing a Compelling Grant to Fund Your Research

  • 1. Writing a compelling grant to fund your research Scott McClelland Craig Cohen Richard Chaisson 6th December 2013 2nd Bi-Annual CFAR SSA Meeting Cape Town, South Africa
  • 2. Overview • Introduction – Components of a research grant – Review criteria and the review process • Novel hypotheses and innovation • Assembling your team • Tackling the approach
  • 3. Key Components of Research Proposal • Title • Budget & Justification • Abstract & Key Personnel • Research Plan
  • 4. Review Criteria • Overall Impact • Significance: How will scientific knowledge be advanced? • Approach: Are the framework, design, methods, and analyses adequately developed, well integrated, well reasoned, and appropriate?
  • 5. Review Criteria • Innovation: Is the project original or does it provide a necessary step for advancing the field? • Investigators: Adequate training/ expertise of investigative team? • Environment: Will the research (and training) environment contribute to the probability of success?
  • 6. Cartoon Credit: Chris O’Hara from Googledocs.com
  • 7. Consider your Audience(s) Two to three primary reviewers
  • 8. Consider your Audience(s) 5 to 15 additional reviewers
  • 9. Research Plan • Hypotheses and Specific Aims • Research Strategy – Significance – Innovation – Approach • Human Subjects
  • 10. Research Plan • Hypotheses and Specific Aims • Research Strategy – Significance – Innovation – Approach • Human Subjects
  • 11. Getting Started “Experiencing a Writers Block” www.torito.nl
  • 12. Start with a Thorough Review of the Relevant Literature
  • 13. Preparing to Write • Comprehensive literature search • Search references of retrieved articles • Read carefully – Consider taking notes or highlighting • Talk with colleagues • Talk with grant contact person
  • 14.
  • 15. Image Credit: Funzug.com Inadequate Preparation Prior to Writing – A Fatal Flaw
  • 16. Hypotheses and Specific Aims • States the research questions (hypotheses) and how they will be addressed (aims) Milliondollardatsun.com Burning Question Big, Big Aim Approach Approach istockphoto.com
  • 17. Hypotheses & Specific Aims • Start with a brief narrative describing long-term goals • Followed by numbered list of aims – Most successful larger applications have 24 aims (3 is typical) – Multiple aims should be clearly related • Should fit on one page • State hypotheses clearly
  • 18. Lack of clear hypothesis – A fatal flaw
  • 19. Sample Structure of Aims Page
  • 20. Innovation • Be careful with innovation. – It is enough to show how the work is new and unique and how it will add significantly to what's known.

Editor's Notes

  1. This should actually be the first section that you write and write and write.Approach 1: The Burning Question Approach.Think of the hypothesis as the hook. This is what gets people interested. The specific aim is the roadmap to show people how you will prove the hypothesis.Approach 2: The Big Big Aim approach. You Aim to do something spectacular; our aim is to develop a cure for HIV-1 infection. Hypothesis is that you can cure HIV-1 by doing XYZ.In approach 2, don’t forget the hypothesisAlso, good to think about Expected Outcome and Significance for each Aim.
  2. If instead your application is highly innovative, you'll need to build a strong case for your ability to challenge the existing paradigm and your reason for doing so. To be innovative, research can shift a current paradigm, OR improve or propose a new application of an existing paradigm. A project does not have to be innovative to score well in peer review.