Whether at home or abroad, women and girls are feeling the lopsided effects of HIV. Put another way, nearly 1,000 young women are newly infected with HIV daily. Trauma and intimate
partner violence (IPV) are but numerous factors driving this epidemic. SAMHSA is undertaking a multifaceted approach to engage behavioral health issues, the SAVA syndemic, and the opioid epidemic through innovative behavioral health programs.
Changing the Narrative for Women & Girls (Tx, Recovery)Alton King
Innovation. Perseverance. Dedication. Adaptation. These are but a few words that describe behavioral health programs that help clients to be treated for their substance use or co-occurring disorder, obtain and/or sustain their recovery, and enjoy a renewed/reinvigorated life of their choosing. Creative interventions will be discussed that canvas the entire U.S. and several of its dependent areas around the globe.
Madridge Journal of AIDS (ISSN: 2638-1958); HIV-related stigma is a global issue. Its perpetuation varies in magnitude across and within countries, and serves as a major barrier to HIV prevention efforts.
Achievements and Implications of HIV Prevention Programme among Female Sex wo...QUESTJOURNAL
Background: Plateau State, Nigeria with HIV prevalence rate of 7.7% as at 2010 had among the highest HIV and syphilis levels in Nigeria, earning itself a reputation of being one of the 12 + 1 states contributing the highest HIV prevalence in Nigeria and described as “hot zone” of HIV infections. Factors responsible for this were not unrelated to the high-risk activities of Female Sex Workers (FSWs). This paper therefore presents achievements and implications HIV prevention among FSWs in Plateau State, Nigeria Methods: This project was an intervention effort focused on delivering evidence-based HIV prevention activities among FSWs in 3 local government areas within the State. The estimated target population for the study was 460 and this project used the minimum prevention package intervention (MPPI). Peer educators were selected and trained among the FSWs to reach out to their peers using cohort session. Data were documented using various monitoring and evaluation tools, entered on the District Health Information Software version 2 and analyzed using Microsoft Excel. Results: A total of 68 community dialogues were held with 1,466 influencers participating in the process. In addition, 601 peers were registered, while 18 persons benefitted from 27 income generation activities aimed at capacity building for FSWs. A total of 642 persons were counseled, tested and shown their results, with 15 persons tested positive resulting in HIV prevalence of 2.3%. Although 10,560 condoms were distributed however, these numbers was below the number of condoms required during the intervention. Conclusion: This intervention was a success. However, more needs to be done with regards to condom distribution and supply among FSWs since there is a crucial role for FSWs to play in the plot of taking the HIV prevalence of Plateau State even further down
Health eNav: Developing a System of Digital HIV Care Navigation in San FranciscoYTH
Health eNavigation or Health eNav is an innovative HIV care navigation model being tested by the San Francisco Department of Public Health. This session will explain how Health eNav will utilize comprehensive digital navigation strategies including text-messaging, social media and geo-spatial platforms to meet youth where they are. Health eNav will also extend the system of tailored, personalized support outside traditional hours of operation. Health eNav harnesses the promise of mhealth within the world’s most complex public health department to develop a system of digital HIV care navigation. Health eNav is your digital companion to help guide you through important decisions, whenever, wherever and however you want it. Health eNav will also extend the system of tailored, personalized support outside traditional work hours. Connection is health. Health eNav is bringing connection to those who need it most to improve health outcomes to create and connect a healthier San Francisco.
Changing the Narrative for Women & Girls (Tx, Recovery)Alton King
Innovation. Perseverance. Dedication. Adaptation. These are but a few words that describe behavioral health programs that help clients to be treated for their substance use or co-occurring disorder, obtain and/or sustain their recovery, and enjoy a renewed/reinvigorated life of their choosing. Creative interventions will be discussed that canvas the entire U.S. and several of its dependent areas around the globe.
Madridge Journal of AIDS (ISSN: 2638-1958); HIV-related stigma is a global issue. Its perpetuation varies in magnitude across and within countries, and serves as a major barrier to HIV prevention efforts.
Achievements and Implications of HIV Prevention Programme among Female Sex wo...QUESTJOURNAL
Background: Plateau State, Nigeria with HIV prevalence rate of 7.7% as at 2010 had among the highest HIV and syphilis levels in Nigeria, earning itself a reputation of being one of the 12 + 1 states contributing the highest HIV prevalence in Nigeria and described as “hot zone” of HIV infections. Factors responsible for this were not unrelated to the high-risk activities of Female Sex Workers (FSWs). This paper therefore presents achievements and implications HIV prevention among FSWs in Plateau State, Nigeria Methods: This project was an intervention effort focused on delivering evidence-based HIV prevention activities among FSWs in 3 local government areas within the State. The estimated target population for the study was 460 and this project used the minimum prevention package intervention (MPPI). Peer educators were selected and trained among the FSWs to reach out to their peers using cohort session. Data were documented using various monitoring and evaluation tools, entered on the District Health Information Software version 2 and analyzed using Microsoft Excel. Results: A total of 68 community dialogues were held with 1,466 influencers participating in the process. In addition, 601 peers were registered, while 18 persons benefitted from 27 income generation activities aimed at capacity building for FSWs. A total of 642 persons were counseled, tested and shown their results, with 15 persons tested positive resulting in HIV prevalence of 2.3%. Although 10,560 condoms were distributed however, these numbers was below the number of condoms required during the intervention. Conclusion: This intervention was a success. However, more needs to be done with regards to condom distribution and supply among FSWs since there is a crucial role for FSWs to play in the plot of taking the HIV prevalence of Plateau State even further down
Health eNav: Developing a System of Digital HIV Care Navigation in San FranciscoYTH
Health eNavigation or Health eNav is an innovative HIV care navigation model being tested by the San Francisco Department of Public Health. This session will explain how Health eNav will utilize comprehensive digital navigation strategies including text-messaging, social media and geo-spatial platforms to meet youth where they are. Health eNav will also extend the system of tailored, personalized support outside traditional hours of operation. Health eNav harnesses the promise of mhealth within the world’s most complex public health department to develop a system of digital HIV care navigation. Health eNav is your digital companion to help guide you through important decisions, whenever, wherever and however you want it. Health eNav will also extend the system of tailored, personalized support outside traditional work hours. Connection is health. Health eNav is bringing connection to those who need it most to improve health outcomes to create and connect a healthier San Francisco.
The most recent data on the target populations of the National HIV/AIDS Strategy in the greater Philadelphia area. Briana Morgan (OHP) first presented this information to a joint meeting of the Ryan White Planning Council and HIV Prevention Planning Council. In January, she gave a similar presentation to the Positive Committee.
Achievements and Implications of HIV Prevention of Mother-toChild Transmissio...QUESTJOURNAL
Background: Mother-to-child transmission is the predominant route through which children contract HIV and can be controlled through Prevention of Mother-to-Child Transmission (PMTCT) programme. This paper presents programme activities on PMTCT conducted among women of reproductive age in Plateau State, Nigeria. Methods: This intervention was carried out among women of reproductive age in eight local government areas of Plateau state. Seven civil society organizations were engaged and provided with funding by Plateau State Agency for the Control of AIDS under the HIV/AIDS fund (HAF) II. A total of 7460 women of reproductive age are the estimated sample size for this intervention and the minimum prevention package intervention was used for this project activities. Data were documented using various monitoring and evaluation tools and DHIS2 while analysis was carried out using Microsoft Excel. Results: The total number of community dialogues/advocacy held was 85 and a total of 1,437 people participated. Seventeen income generation activities were carried out in this intervention and 131 people benefitted from it. A total of 87,028 pieces of condom were distributed with majority (88.5%) being distributed in 2014. Only a total of 5606 women were counseled tested and received result and 44 (0.8%) were tested positive. A total of 3275 women were referred for antenatal care during this programme and more than half (52.0%) were referred in 2014. Conclusion: This intervention has been helpful in reducing the burden of HIV and AIDS among women of reproductive age in Plateau State. However, the coverage of minimum prevention package intervention was low. More needs to be done in terms of coverage in future programmes and the intervention should also be extended to other local government areas.
America cares hiv-aids in black america#GOMOJO, INC.
Increase community awareness of HIV/AIDS and HIV prevention strategies.
Increase community understanding of the clinical research process.
Develop and strengthen relationships with community stakeholders, including (but not limited to) medical care providers, STD/HIV counseling and testing providers, faith leaders, Non Governmental Organizations and Community Based Organizations.
Increasingly, African Americans in general are recognizing that HIV is wreaking devastation across our communities. Those who have joined the fight against HIV and AIDS in Black communities are coming to understand that it is a difficult and multifaceted problem—but that it is also a winnable war. With this report, we aim to arm those people with the information they need to get there.
How Africa turned AIDS around By Michel Sidibé Celebrating 50 Years of Africa...Dr Lendy Spires
Michel Sidibé Executive Director UNAIDS At the May 2013 African Union Summit celebrating the 50 years of African unity, a new commission will be launched to explore HIV and global health in the post-2015 debate. “The UNAIDS and Lancet commission: from AIDS to sustainable health” will be co-chaired by Malawi President Joyce Banda, African Union Commission Chairperson Nkosazana Dlamini Zuma and London School of Hygiene and Tropical Medicine Director Peter Piot.
The pace of progress is quickening in Africa. Nowhere have we seen this more clearly than in the AIDS response. Fewer people are dying from AIDS. The number of HIV infections is coming down, with young Africans leading the prevention revolution. There is true hope that in a matter of years, Africa will reach an AIDS-free generation. It has taken a massive shift in how we work together. It has required leaders to show immense courage, passion and action from all sectors. It has taken a united Africa. I am not saying it has been easy— but it has happened. We have a shared vision of zero new HIV infections, zero discrimination and zero AIDS-related deaths.
And today there is an African Union endorsement of a new Roadmap to accelerate progress in HIV, Tuberculosis and Malaria—through shared responsibility and global solidarity. Given the extraordinary history of the AIDS response in Africa—in terms of both galvanizing political support and mobilizing resources and communities—the Roadmap sees AIDS as a pathfinder for tuberculosis, malaria and other diseases affecting the continent that require African-sourced solutions. Leadership, it turns out, was that elusive magic bullet. It is the “disruptive innovation” that has irrevocably changed the course of AIDS and now can do even more. As we look to our future goals, I am confident that African leadership can be UNAIDS | Special report with vision and action we can change the world
Lea Narciso from SA Health discusses the changing epidemic in South Australia, which now includes an increasing number of people born overseas, and the government's policy response. This presentation was given at the AFAO Community Hub at the ASHM 2015 conference.
The most recent data on the target populations of the National HIV/AIDS Strategy in the greater Philadelphia area. Briana Morgan (OHP) first presented this information to a joint meeting of the Ryan White Planning Council and HIV Prevention Planning Council. In January, she gave a similar presentation to the Positive Committee.
Achievements and Implications of HIV Prevention of Mother-toChild Transmissio...QUESTJOURNAL
Background: Mother-to-child transmission is the predominant route through which children contract HIV and can be controlled through Prevention of Mother-to-Child Transmission (PMTCT) programme. This paper presents programme activities on PMTCT conducted among women of reproductive age in Plateau State, Nigeria. Methods: This intervention was carried out among women of reproductive age in eight local government areas of Plateau state. Seven civil society organizations were engaged and provided with funding by Plateau State Agency for the Control of AIDS under the HIV/AIDS fund (HAF) II. A total of 7460 women of reproductive age are the estimated sample size for this intervention and the minimum prevention package intervention was used for this project activities. Data were documented using various monitoring and evaluation tools and DHIS2 while analysis was carried out using Microsoft Excel. Results: The total number of community dialogues/advocacy held was 85 and a total of 1,437 people participated. Seventeen income generation activities were carried out in this intervention and 131 people benefitted from it. A total of 87,028 pieces of condom were distributed with majority (88.5%) being distributed in 2014. Only a total of 5606 women were counseled tested and received result and 44 (0.8%) were tested positive. A total of 3275 women were referred for antenatal care during this programme and more than half (52.0%) were referred in 2014. Conclusion: This intervention has been helpful in reducing the burden of HIV and AIDS among women of reproductive age in Plateau State. However, the coverage of minimum prevention package intervention was low. More needs to be done in terms of coverage in future programmes and the intervention should also be extended to other local government areas.
America cares hiv-aids in black america#GOMOJO, INC.
Increase community awareness of HIV/AIDS and HIV prevention strategies.
Increase community understanding of the clinical research process.
Develop and strengthen relationships with community stakeholders, including (but not limited to) medical care providers, STD/HIV counseling and testing providers, faith leaders, Non Governmental Organizations and Community Based Organizations.
Increasingly, African Americans in general are recognizing that HIV is wreaking devastation across our communities. Those who have joined the fight against HIV and AIDS in Black communities are coming to understand that it is a difficult and multifaceted problem—but that it is also a winnable war. With this report, we aim to arm those people with the information they need to get there.
How Africa turned AIDS around By Michel Sidibé Celebrating 50 Years of Africa...Dr Lendy Spires
Michel Sidibé Executive Director UNAIDS At the May 2013 African Union Summit celebrating the 50 years of African unity, a new commission will be launched to explore HIV and global health in the post-2015 debate. “The UNAIDS and Lancet commission: from AIDS to sustainable health” will be co-chaired by Malawi President Joyce Banda, African Union Commission Chairperson Nkosazana Dlamini Zuma and London School of Hygiene and Tropical Medicine Director Peter Piot.
The pace of progress is quickening in Africa. Nowhere have we seen this more clearly than in the AIDS response. Fewer people are dying from AIDS. The number of HIV infections is coming down, with young Africans leading the prevention revolution. There is true hope that in a matter of years, Africa will reach an AIDS-free generation. It has taken a massive shift in how we work together. It has required leaders to show immense courage, passion and action from all sectors. It has taken a united Africa. I am not saying it has been easy— but it has happened. We have a shared vision of zero new HIV infections, zero discrimination and zero AIDS-related deaths.
And today there is an African Union endorsement of a new Roadmap to accelerate progress in HIV, Tuberculosis and Malaria—through shared responsibility and global solidarity. Given the extraordinary history of the AIDS response in Africa—in terms of both galvanizing political support and mobilizing resources and communities—the Roadmap sees AIDS as a pathfinder for tuberculosis, malaria and other diseases affecting the continent that require African-sourced solutions. Leadership, it turns out, was that elusive magic bullet. It is the “disruptive innovation” that has irrevocably changed the course of AIDS and now can do even more. As we look to our future goals, I am confident that African leadership can be UNAIDS | Special report with vision and action we can change the world
Lea Narciso from SA Health discusses the changing epidemic in South Australia, which now includes an increasing number of people born overseas, and the government's policy response. This presentation was given at the AFAO Community Hub at the ASHM 2015 conference.
Global Medical Cures™ | HIV Among Women
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
October 7, 2019
On October 7, 2019, the Harvard Global Health Institute will host a one-day symposium to explore what enabled this visionary program, and to showcase how it has transformed not just the worldwide HIV/AIDS response but global health delivery more broadly.
There are many lessons learned in PEPFAR’s story - from what it took to build a supply chain where there was none, to establishing the use of generic antiretroviral therapies (ARTs) and leveraging human capacity. This event convened the early architects of PEPFAR as well as experts and implementers currently leading the charge. We took a historically informed look at what it will take to stop global transmission, and shared tools useful for others hoping to move the needle on vexing problems in global health.
For more information, visit our website at https://petrieflom.law.harvard.edu/events/details/15-years-of-pepfar
Table of Contents
Abstract……………………………………………………………………………3
Introduction……………………………………………………………………......4
Literature Review…………………..…………………………………………..... 7
Complications……………………………………………………………………12
Methodology…………………………………………………………………......23
Inclusion Criteria………………………………………………………………...27
Exclusion Criteria………………………………………………………………..30
Discussion………………………………………………………………………..35
Limitations………………………………………………………………………38
Conclusion………………………………………………………………………44
References………………………………………………………………………53
Abstract
Infection with the human immunodeficiency virus (HIV) creates acquired immunodeficiency syndrome (AIDS), which attacks the cells of the immune system, and damages or destroys their function. The virus is spread through immediate contact with an infected mucosal membrane or bodily fluids such as blood, semen, and breast milk. After an introductory frequently asymptomatic stage, skin predicaments and upper respiratory tract infections occur, and patients start to lose weight. Persistent diarrhea, chronic fever, fungal or bacterial contaminations, and tuberculosis may follow. As the infection advances, the immune system degenerates, gradually losing its strength to fight other infections and diseases, and eventually leading to “immune deficiency”. Immunodeficiency individuals are prone to opportunistic infections and tumors. There is no antidote or vaccine currently ready, but the availability of active antiretroviral treatment has radically lowered mortality and prolonged survival times of HIV-infected individuals in high-income nations. However, antiretroviral medications are usually costly, and access to diagnostic tests and treatments in low- to middle-income class families and third world countries has been inadequate. Over the preceding decade, competition from universal pharmaceutical corporations has dramatically reduced the cost of antiretroviral, although brand-new generation medications continue prohibitively pricey. Most children get HIV through perinatal transmission through pregnancy, childbirth, or while breastfeeding. Prevention programs can decrease the risk of transmission from 30-40% down to less than 5%. Improved admittance to these programs will lead to the higher health of HIV-positive expecting women and lowering numbers of newborns infected.
Introduction
According to the Centers for Disease Control and Prevention, of all ethnic groups in the United States, African Americans have faced the most challenges and largest burden by the HIV/AIDS epidemic since 1981 (CDC, 2016). Distinguished with various races and ethnicities, African Americans serve a more significant amount of new HIV diagnoses, those existing with HIV, and those ever decided to have AIDS. In 2014, it was reported that 44% (19,540) of newly diagnosed HIV cases were published in the United States were among African Americans, who constitute of 12% of the US population (CDC, 2016). During this same year, it is expected that presently diagnosed HIV cas.
Sharing from USAID:
The U.S. Agency for International Development (USAID) is pleased to announce the release of its “Annual Progress Report to Congress: Global Health Programs FY 2014.” The report presents a summary of USAID’s key global health accomplishments during the previous fiscal year. From improving children’s nutrition to supporting antiretroviral treatment for millions of individuals, USAID programs had a great impact in 2014.
As the largest investor in global health, USAID is leading efforts to improve and save lives worldwide. In partnership with countries, non-governmental organizations, the faith-based community, and the private sector, the Agency is reaching people with the greatest need in the most remote areas. USAID works to further President Barack Obama’s vision to end extreme poverty through its ongoing contributions to ending preventable child and maternal deaths, creating an AIDS-free generation and protecting communities from infectious diseases.
Today we stand at a vital threshold. Within our grasp is the opportunity to end 30 years of suffering and death due to HIV/AIDS. Individuals and communities around the world have been mobilized toward prevention, and existing treatment can prolong life for many years. While we celebrate these successes, we reject any modicum of complacency. Now is the time to double down and finish the job. The world is fighting AIDS today just as it had previously fought to eliminate smallpox. For centuries, smallpox was a feared scourge that killed nearly half of those infected and maimed those that survived. A worldwide campaign to end the disease began in earnest in the late 1960s and by 1980 smallpox was officially eradicated.
Planet Aid anticipates the day when AIDS, too, will be stopped. To this end, we have been helping mobilize communities around the globe to increase HIV/AIDS prevention and care. With this special issue of the Planet Aid Post, we focus on the battle ahead. We also extend a warm welcome to those joining us on the forefront of this work,
This presentation provides an overview of the role that policy advocacy has played in activating greater visibility for the female condom and increased procurement in the developing world. It highlights the important role that third-party partnerships play in mobilizing evidence of need and demand for health products in the developing world. The presentation identifies policy advocacy and social marketing as essential complements to a comprehensive marketing and promotion strategy.
National and international perspectives of health.pptxlucascyrus
The HIV epidemic affects the health of individuals as well as the households. With effective awareness campaigns and UNAIDS cautions an equal progress in reduction of HIV infections have been observed.
Join us as we discuss best practices for integrating HIV prevention (e.g. HIV testing, PrEP and linkage to care) into primary care within the context of enhancing clinical workforce development.
Panelists:
• Marwan Haddad, MD, MPH, AAHIVS, Medical Director, Center for Key Populations, Community Health Center, Inc.
• Jeannie McIntosh, APRN, FNP-C, AAHIVS, Family Nurse Practitioner, Center for Key Populations, Community Health Center, Inc.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
Women & Girls: Behavioral Health, HIV, HEP and more
1. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Women & Girls: Taking on Behavioral
Health, HIV, and Hepatitis for Better
Health Outcomes
Alton J. King, MBA
Public Health Advisor (SAMHSA/CSAT/HSB/HIV)
2. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Disclosures
Presenters have no financial interest to disclose.
This continuing education activity is managed and accredited by
Professional Education Services Group in cooperation with HSRA
and LRG. PESG, HSRA, LRG and all accrediting organization do not
support or endorse any product or service mentioned in this
activity.
PESG, HRSA, and LRG staff has no financial interest to disclose.
3. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Learning Objectives
At the conclusion of this activity, the participant will be able to:
1. Discuss the feasibility of integrating IPV and trauma into your
programmatic activities
2. Recognize medication-assisted treatment’s (MAT) role to
engage the opioid crisis
3. Recognize the importance of recovery and resiliency to
sustain improved health outcomes
5. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
A Global Context (HIV)
The Lancet 2015 386, 171-218DOI: (10.1016/S0140-6736(15)60658-4)
6. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
A Call to Action - 2020
by 2020 90-90-90 (Treatment) 500,000 (New infections) 0 (Discrimination)
by 2030 90-90-90 (Treatment) 200,000 (New infections) 0 (Discrimination)
7. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Yet, Action Still Misses …
Px Wire: A Quarterly Update on HIV PreventionResearch | Volume 7 | No.4 | October–December 2014
Today’stargets
leavea
prevention
gap.
UNAIDS 2014 Targets for 2020
Diagnosed
OnTreatment
Virally Suppressed
90% 90% 90%
On
Treatment
Needle
Exchange
Ending the
AIDS epidemic
by 2030 takes
comprehensive
targets and
action.
8. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Archbishop Desmond Tutu
International Women’s Day 2016
(March 6)
“But If we hold back
women, we hold back our
societies. If we allow
women to be women, and
let them use the gift that
God has given to them, our
communities will flourish.”
The Elders Speak Volumes
9. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Globally, A Burden on Women
Women comprise 51% (17.8 million) of PLWHAs
HIV/AIDS is the leading cause of death among
women of reproductive age (15 – 49)
Young women and adolescent girls account for:
- 58% of all new HIV infections among young people
- 60% of all young people living with HIV/AIDS
Female sex workers are ~14x more likely to be
infected than other women of reproductive age
UNAIDS, 2015 estimates from the AIDSinfo online database.*; Stefan Baral et al. (15 March 2012)
10. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Universal Factors for Women
Gender-based (GBV) and intimate partner violence
(IPV)
Gender inequality and discrimination
o Inclusive of unequal cultural, social, and economic status
Women living with HIV often experience violence
due to their HIV status, including violations of their
sexual and reproductive rights
Lack of access to healthcare services
Discriminatory criminal laws linked to HIV
11. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Speaking in #hashtags (U.S.)
* Socialconversation via Twitter covering the period September 8– December 1, 2014
http://www.bigmountaindata.com/whyistayed-whyileft-a-data-analysis/
A social
conversation on
domestic
violence*
Domestic
violence is one
of many forms
of IPV or GBV
12. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Realities for U.S. Women
Experiencing the substance abuse, violence, and
HIV/AIDS (SAVA) syndemic ↑ (nearly 7x) the likelihood
of depressive symptoms
Black and Latina women are disproportionately
affected by HIV and IPV
o 40.4% of reported lifetime IPV and 80% of new HIV infections
Women account for 20% of new HIV infections
o African Americans constituted 63% of women diagnosed
Blacks and Latinas represent 28% of all women but
account for 80% of HIV cases among women
Illangasekare, 2013; Morales-Aleman et. al, 2014; Chen et al., 2013; U.S. Centers for Disease Control and Prevention, HIV Surveillance Report 2013
13. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
A Sampling of Substances
14. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
300+ million Americans, yet …
2014 National Survey on Drug Use and Health (NSDUH; SAMHSA)
15. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Substance(s) of Choice in SUDs
2014 NSDUH(SAMHSA)
16. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
A Gap in SUD Treatment Exists
2014 NSDUH(SAMHSA)
17. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
TCE-HIV Engages SUD and HIV
Since 2000, the TCE-HIV program has:
Engaged over 100,000 clients in SUD treatment
Established the HIV status for 40,000+ clients
Supported 13,000+ clients in HIV counseling and
treatment services
Supported nearly 12,000 clients in HIV case
management services and 18,000 clients in HIV-
related medical care
Delivered HIV/AIDS education to 30,000+ clients
AllTCE-HIV programs through February 2015
18. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Changing Lives for Clients
TCE-HIV: Minority Womenprogram (FY13) as of February 2015
Measure Type # Valid
Cases
% at Intake % at 6-
months
% (∆)
Change
Abstinence: No alcohol or illegal drugs 9,534 30.0 52.5 74.9
Stability in Housing: had a permanent place to
live in the community
9,551 43.5 46.8 7.6
Measure Type # Valid
Cases
% at Intake % at 6-
months
% (∆)
Change
Anxiety 1,775 61.8 47.6 -23.0
Depression 1,776 58.2 44.3 -24.0
Injected illegal drugs 1,787 4.5 2.8 -38.3
Had unprotected sexual contact 543 72.4 64.6 -10.7
Had unprotected sexual contact with someone
high on any substance
298 30.2 18.5 -38.9
TCE-HIV program (FY12 & FY13) as of February 2015
19. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
A Snapshot of Who We Serve
Primarily Black (41.5%)
and Latino (43.6%)
1 in 3 possess HS/GED
96.3% below FPL (200%)
TCE-HIV: Minority Womenprogram (FY13) as of February 2015
0.4%
97.0%
2.6%
0.0%
Male
Female
Transgender
Other
17.6%
82.4%
Employed
Unemployed
20. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
President Barack H. Obama
World AIDS Day 2015
(March 6)
“... ending the epidemic
also requires a focus on
prevention. Especially
when it comes to
empowering our young
women and girls to
protect their own health,
secure economic
opportunity, and pursue
their dreams.”
POTUS Reminds Us That
21. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Let’s Get Trauma-informed!!
• Realizes widespread
impact of trauma and
paths for recovery;
• Recognizes signs and
symptoms of trauma;
• Responds by integrating
trauma knowledge; and
• Seeks to actively resist
re-traumatization
SAMHSA's Concept of Trauma and Guidance for a Trauma-Informed Approach
22. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
A Game Changer for Women …
When trauma-informed care (TIC) is integrated into
SUD treatment, it can:
enhance HIV care retention and medication
adherence
improve the health/wellness of people living with or
at risk for HIV and have histories of trauma
reduce disparities among communities of color
enrich the quality of life for communities of color
SAMHSA’s TIP 57: Trauma-Informed Care in Behavioral Health Services
23. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Engaging the SAVA Syndemic
Violence Intervention To Enhance Lives (VITEL)
o SMAIF funded (awarded 2015, continuation in 2016)
o Novel intervention incorporating IPV screening with
concurrent SUD screening and follow-on referral services
o A 2013 White House report reaffirms attention on
trauma, HIV, and violence against women & young girls
To-date results
o >500 clients and nearly 100 staff educated on IPV
o 22.4% clients screened positive for IPV (past 30 days)
o 93% clients referred to trauma-informed services
Secretary’s Minority AIDS Initiative Fund (SMAIF) provides supplemental funding to existing TCE-HIV: Minority Women(TFY13) grantees per funding opportunity announcements (FOAs) TI-15-013 and TI-16-010
24. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Rounding Out the Circle of Care
Over 1,600 women of color and clients have sustained
their HIV negative status as a result of this program:
TCE-HIV: Minority Womenprogram (FY13)
Provides SUD treatment
Provides TIC services in a safe and
trusting environment
Provides HIV and Hepatitis testing
Provides coordinated care for SUD,
HIV, Hepatitis, and trauma
Maintains overall health and
wellbeing
25. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Don’t Forget Program Evolution
• Require IPV screening
• Support MAT
• Link and refer clients for
PrEP and PEP
• Require Hepatitis A + B
vaccinations
• Support syringe services
programs (sans needles,
injecting equipment)
Latest FOA, TI-16-011, updated for FY16 &beyond; Care Coordination (Center of Excellence inCare Coordination)
26. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
A Friendly Reminder That …
“Each of us has a
role to play in
giving every man,
woman and child on
Earth access to life-
saving treatment
and care.” President Barack H. Obama
World AIDS Day 2012
(December 1)
27. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
THANK YOU!!
Alton.King@samhsa.hhs.gov
28. 2016 NATIONAL RYAN WHITE CONFERENCE ON HIV CARE & TREATMENT
Obtaining CME/CE Credit
If you would like to receive continuing
education credit for this activity, please
visit:
http://ryanwhite.cds.pesgce.com
Editor's Notes
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SDGs help to reduce the impact of the social determinants of health
Many of these “buckets” put key populations at risk
On 6 March, to mark International Women’s Day, Graça Machel and Desmond Tutu hosted a Twitter Q&A on gender inequality and women’s rights.
http://theelders.org/article/if-we-hold-back-women-we-hold-back-society
Full transcript is here http://theelders.org/article/what-can-we-do-change-gender-equation
http://www.unwomen.org/en/what-we-do/hiv-and-aids/facts-and-figures
* Additional disaggregations correspond to unpublished estimates for 2015 provided by UNAIDS, obtained from country-specific models of their AIDS epidemics.
Stefan Baral et al. (15 March 2012) “Burden of HIV among female sex workers in low-income and middle-income countries: a systematic review and meta-analysis”, The Lancet Infectious Diseases, vol. 12, No. 7. p. 542.
References:
Illangasekare, S., Burke, J., Chander, G., & Gielen, A. (2013) The Syndemic Effects of Intimate Partner Violence, HIV/AIDS, and Substance Abuse on Depression among Low-Income Urban Women. Journal of Urban Health. 90(5):934-947.
Morales-Alemán, M. M., Hageman, K., Gaul, Z. J., Le, B., Paz-Bailey, G., Sutton, M. Y. (2014) Intimate Partner Violence and Human Immunodeficiency Virus Risk Among Black and Hispanic Women. Am J Prev Med. 47(6):689–702.
Chen P-H., Jacobs, A., Rovi, S. L. D. (2013) Intimate partner violence: office screening for victims and perpetrators of IPV. FP Essentials. 412:11-17.
Substance use disorders (SUDs) and co-occurring disorders (CODs) are well-documented initiators and amplifiers of risky behaviors and HIV progression
52% of people over the age of 12, and over 60% of adults over age 21 are current drinkers, with 44% of current drinkers having had at least one episode of binge drinking in the past year, and 12% of current drinkers considered heavy drinkers
Note: SUD refers to dependence or abuse in the past year related to the use of alcohol or illicit drugs in that same period. Estimated # of individuals having disorders for specific substances do not sum to the 21.5 million people with any SUD because people could have disorders associated with their use of more than one substance (e.g., polysubstance).
Note: Receipt of Specialty Treatment in the Past Year among People Aged 12 or Older Who Needed Substance Use Treatment: 2014
Client Demographics (both FY12 & FY13)
Clients are primarily Black (50.6%) and Latino (32.2%), but also includes AI/AN (<1.5%) and Asians (<1%)
70.1% of clients’ educational background range from none (0.1%) to having a high school diploma/GED (37.1%)
92.4% of clients live below the 2015 Federal Poverty Level (200%)
23.4% of clients are employed (full/part-time)
According to SAMHSA’s concept of a trauma-informed approach, “A program, organization, or system that is trauma-informed” embodies the above slide’s bullet-points (Realizes, Recognizes, Responds, Re-traumatization)
There are a number of terms being used in the health field related to trauma. For the purposes of this presentation when we say “Trauma-informed” we mean a trauma-informed approach to the delivery of behavioral health services that includes an understanding of trauma and an awareness of the impact it can have across settings, services, and populations. It involves viewing trauma through an ecological and cultural lens and recognizing that context plays a significant role in how individuals perceive and process traumatic events, whether acute or chronic.
http://www.samhsa.gov/nctic/trauma-interventions
http://store.samhsa.gov/shin/content/SMA14-4884/SMA14-4884.pdf
Trauma Informed Care is a strengths-based framework that is grounded in an understanding of and responsiveness to the impact of trauma…that emphasizes physical, psychological, and emotional safety for both providers and survivors…and, that creates opportunities for survivors to rebuild a sense of control and empowerment.”–(Hopper, Bassuk & Olivet, 2010, pg. 82)
http://store.samhsa.gov/shin/content/SMA14-4816/SMA14-4816.pdf
73 clients enrolled in intensive IPV-specific classes and at least 2 clients receiving IPV-specific individual counseling
SAMHSA’s TCE-HIV: Minority Women program (FY13) addresses all the steps in the HIV Care Continuum
Other things like STIs, nutrition, etc. cannot be overlooked; our work must continue its evolution towards treating the whole person
Remember these words in moments of despair, frustration, and angst