SlideShare a Scribd company logo
What are two possible causes of B12 deficiency? Provide a detialed answer with literature
review source.
Solution
Answer:
Vitamin B12 is not synthesized by the body, and thus requires intake of animal foods rich in
vitamin B12 or through supplements. Vitamin B12 helps in production of DNA and RNA, and
works in concert with folic acid to make RBCs.
Two possible causes of Vitamin B12 deficiency are:
1. Thinning of the stomach lining due to atrophic gastritis:
Atrophic gastritis is often caused by the H. pylori. The bacterial infection frequently occurs
during childhood and gets worse over time if it isn’t treated.
Direct contact with the feces, vomit, or saliva of an infected person can spread the disease. It
may also occur after eating food or drinking water that’s contaminated with the bacteria.
When autoantibodies attack healthy stomach cells, autoimmune atrophic gastritis develops.
These antibodies target the gastric juice producing stomach cells. These antibodies may also
attack intrinsic factors, which are proteins released by stomach cells that help in vitamin B12
absorption. A lack of intrinsic factor results in pernicious anaemia, and low vitamin B12 levels in
the body.
(MLO Med Lab Obs. 2007 Feb;39(2):28, 30-1.
Gut. 1964 Feb;5:27-37.)
2. Removed of part of the stomach or small intestine through surgery, including weight loss
surgery:
Bariatric surgery involves gut manipulation that alters the natural absorption of nutrients, thus
nutritional deficiencies can develop. The most common deficiencies are vitamin B12, folate,
zinc, iron, copper, calcium, and vitamin D and can lead to secondary problems, such as
osteoporosis.
Dietary supplementation are often given following surgery to avoid deficiency complications,
although deficiency symptoms may be evident after months of surgery. Bariatic patients are at
increased risk as their digestive have undergone alteration such that it interferes with the
absorption of vitamins.
(Curr Drug Metab. 2012 Nov; 13(9): 1345–1355.
Pediatr Clin North Am. 2009 Oct; 56(5): 1105–1121.)

More Related Content

Similar to What are two possible causes of B12 deficiency Provide a detialed a.pdf

vit b12.pptx
vit b12.pptxvit b12.pptx
vit b12.pptx
ssuser3cec66
 
Causes of vitamin b12 and folate deficiency
Causes of vitamin b12 and folate deficiencyCauses of vitamin b12 and folate deficiency
Causes of vitamin b12 and folate deficiency
frankln
 
Pernicious-Anemia-An-Overview (1).pptx
Pernicious-Anemia-An-Overview (1).pptxPernicious-Anemia-An-Overview (1).pptx
Pernicious-Anemia-An-Overview (1).pptx
MohetLP
 
Nutrition
NutritionNutrition
Nutrition
ANIL KUMAR
 
Could You Have a Vitamin B12 Deficiency.pdf
Could You Have a Vitamin B12 Deficiency.pdfCould You Have a Vitamin B12 Deficiency.pdf
Could You Have a Vitamin B12 Deficiency.pdf
The Lifesciences Magazine
 
NUTRITIONAL PROBLEMS IN INDIA.pdf
NUTRITIONAL PROBLEMS IN INDIA.pdfNUTRITIONAL PROBLEMS IN INDIA.pdf
NUTRITIONAL PROBLEMS IN INDIA.pdf
manjarigupta43
 
Cyanocobalamin deficiency and toxicity
Cyanocobalamin deficiency and toxicityCyanocobalamin deficiency and toxicity
Cyanocobalamin deficiency and toxicity
Domina Petric
 
Megaloblastic anemia
 Megaloblastic anemia Megaloblastic anemia
Megaloblastic anemia
Ravi Rastogi
 
B12—-an———-Folate-deficiency-Anemia.pptx
B12—-an———-Folate-deficiency-Anemia.pptxB12—-an———-Folate-deficiency-Anemia.pptx
B12—-an———-Folate-deficiency-Anemia.pptx
simamhammed33
 
1. Vitamins and Minerals.ppt
1. Vitamins and Minerals.ppt1. Vitamins and Minerals.ppt
1. Vitamins and Minerals.ppt
myLord3
 
Megaloblastic anaemia (anemia) pharmacology
Megaloblastic anaemia  (anemia) pharmacologyMegaloblastic anaemia  (anemia) pharmacology
Megaloblastic anaemia (anemia) pharmacology
PradipChauhan27
 
Pernicious Anaemia (pa)
Pernicious Anaemia (pa)Pernicious Anaemia (pa)
Pernicious Anaemia (pa)
aswathydhiya
 
Marasmus kwashiorkor
Marasmus kwashiorkorMarasmus kwashiorkor
Marasmus kwashiorkornajahkh
 
Why is it recommended that vegans take an oral vitamin B12 supplemen.pdf
Why is it recommended that vegans take an oral vitamin B12 supplemen.pdfWhy is it recommended that vegans take an oral vitamin B12 supplemen.pdf
Why is it recommended that vegans take an oral vitamin B12 supplemen.pdf
archanenterprises
 
Macrocytic ANmeia.pptx
Macrocytic ANmeia.pptxMacrocytic ANmeia.pptx
Macrocytic ANmeia.pptx
VijayDavid8
 
Water Soluble Vitamins
Water Soluble VitaminsWater Soluble Vitamins
Water Soluble Vitamins
Khaled921041
 
ppt on malabsorptions.pptx
ppt on malabsorptions.pptxppt on malabsorptions.pptx
ppt on malabsorptions.pptx
RutuparnaSatapathy
 
Vitamins ppt
Vitamins pptVitamins ppt
Vitamins ppt
ARYARAJ BARUA
 
PTS BOOK final 2019.pdf
PTS BOOK final 2019.pdfPTS BOOK final 2019.pdf
PTS BOOK final 2019.pdf
MehmoodaKhowaja1
 
Vitamins
VitaminsVitamins

Similar to What are two possible causes of B12 deficiency Provide a detialed a.pdf (20)

vit b12.pptx
vit b12.pptxvit b12.pptx
vit b12.pptx
 
Causes of vitamin b12 and folate deficiency
Causes of vitamin b12 and folate deficiencyCauses of vitamin b12 and folate deficiency
Causes of vitamin b12 and folate deficiency
 
Pernicious-Anemia-An-Overview (1).pptx
Pernicious-Anemia-An-Overview (1).pptxPernicious-Anemia-An-Overview (1).pptx
Pernicious-Anemia-An-Overview (1).pptx
 
Nutrition
NutritionNutrition
Nutrition
 
Could You Have a Vitamin B12 Deficiency.pdf
Could You Have a Vitamin B12 Deficiency.pdfCould You Have a Vitamin B12 Deficiency.pdf
Could You Have a Vitamin B12 Deficiency.pdf
 
NUTRITIONAL PROBLEMS IN INDIA.pdf
NUTRITIONAL PROBLEMS IN INDIA.pdfNUTRITIONAL PROBLEMS IN INDIA.pdf
NUTRITIONAL PROBLEMS IN INDIA.pdf
 
Cyanocobalamin deficiency and toxicity
Cyanocobalamin deficiency and toxicityCyanocobalamin deficiency and toxicity
Cyanocobalamin deficiency and toxicity
 
Megaloblastic anemia
 Megaloblastic anemia Megaloblastic anemia
Megaloblastic anemia
 
B12—-an———-Folate-deficiency-Anemia.pptx
B12—-an———-Folate-deficiency-Anemia.pptxB12—-an———-Folate-deficiency-Anemia.pptx
B12—-an———-Folate-deficiency-Anemia.pptx
 
1. Vitamins and Minerals.ppt
1. Vitamins and Minerals.ppt1. Vitamins and Minerals.ppt
1. Vitamins and Minerals.ppt
 
Megaloblastic anaemia (anemia) pharmacology
Megaloblastic anaemia  (anemia) pharmacologyMegaloblastic anaemia  (anemia) pharmacology
Megaloblastic anaemia (anemia) pharmacology
 
Pernicious Anaemia (pa)
Pernicious Anaemia (pa)Pernicious Anaemia (pa)
Pernicious Anaemia (pa)
 
Marasmus kwashiorkor
Marasmus kwashiorkorMarasmus kwashiorkor
Marasmus kwashiorkor
 
Why is it recommended that vegans take an oral vitamin B12 supplemen.pdf
Why is it recommended that vegans take an oral vitamin B12 supplemen.pdfWhy is it recommended that vegans take an oral vitamin B12 supplemen.pdf
Why is it recommended that vegans take an oral vitamin B12 supplemen.pdf
 
Macrocytic ANmeia.pptx
Macrocytic ANmeia.pptxMacrocytic ANmeia.pptx
Macrocytic ANmeia.pptx
 
Water Soluble Vitamins
Water Soluble VitaminsWater Soluble Vitamins
Water Soluble Vitamins
 
ppt on malabsorptions.pptx
ppt on malabsorptions.pptxppt on malabsorptions.pptx
ppt on malabsorptions.pptx
 
Vitamins ppt
Vitamins pptVitamins ppt
Vitamins ppt
 
PTS BOOK final 2019.pdf
PTS BOOK final 2019.pdfPTS BOOK final 2019.pdf
PTS BOOK final 2019.pdf
 
Vitamins
VitaminsVitamins
Vitamins
 

More from armsnoida

Match appropriately. Best fit. stratum corneum papillary region ad.pdf
Match appropriately. Best fit.  stratum corneum  papillary region  ad.pdfMatch appropriately. Best fit.  stratum corneum  papillary region  ad.pdf
Match appropriately. Best fit. stratum corneum papillary region ad.pdf
armsnoida
 
In your own words does Enclave as a unit of security does it describe.pdf
In your own words does Enclave as a unit of security does it describe.pdfIn your own words does Enclave as a unit of security does it describe.pdf
In your own words does Enclave as a unit of security does it describe.pdf
armsnoida
 
I need help answering both these questionsQuestion 5 1. A dip.pdf
I need help answering both these questionsQuestion 5 1. A dip.pdfI need help answering both these questionsQuestion 5 1. A dip.pdf
I need help answering both these questionsQuestion 5 1. A dip.pdf
armsnoida
 
How would you investigate the question about the probability of matc.pdf
How would you investigate the question about the probability of matc.pdfHow would you investigate the question about the probability of matc.pdf
How would you investigate the question about the probability of matc.pdf
armsnoida
 
How did the issues of sectionalism reemerge in 1850, what was the pr.pdf
How did the issues of sectionalism reemerge in 1850, what was the pr.pdfHow did the issues of sectionalism reemerge in 1850, what was the pr.pdf
How did the issues of sectionalism reemerge in 1850, what was the pr.pdf
armsnoida
 
How is localization of Gap gene expression achieved in the Drosophil.pdf
How is localization of Gap gene expression achieved in the Drosophil.pdfHow is localization of Gap gene expression achieved in the Drosophil.pdf
How is localization of Gap gene expression achieved in the Drosophil.pdf
armsnoida
 
For the following ordinary differential equations, identify their de.pdf
For the following ordinary differential equations, identify their de.pdfFor the following ordinary differential equations, identify their de.pdf
For the following ordinary differential equations, identify their de.pdf
armsnoida
 
Find two models of incidence geometry, each with exactly four points.pdf
Find two models of incidence geometry, each with exactly four points.pdfFind two models of incidence geometry, each with exactly four points.pdf
Find two models of incidence geometry, each with exactly four points.pdf
armsnoida
 
Finish the following natural deduction proofs SolutionThe two .pdf
Finish the following natural deduction proofs SolutionThe two .pdfFinish the following natural deduction proofs SolutionThe two .pdf
Finish the following natural deduction proofs SolutionThe two .pdf
armsnoida
 
Find the most general f. Use C for the constant of the first anti-de.pdf
Find the most general f. Use C for the constant of the first anti-de.pdfFind the most general f. Use C for the constant of the first anti-de.pdf
Find the most general f. Use C for the constant of the first anti-de.pdf
armsnoida
 
Explain the concept of diaspora and distinguish between voluntary and.pdf
Explain the concept of diaspora and distinguish between voluntary and.pdfExplain the concept of diaspora and distinguish between voluntary and.pdf
Explain the concept of diaspora and distinguish between voluntary and.pdf
armsnoida
 
Does S_2 span P_2 Solutionlets calculate the dimension of S_2.pdf
Does S_2 span P_2 Solutionlets calculate the dimension of S_2.pdfDoes S_2 span P_2 Solutionlets calculate the dimension of S_2.pdf
Does S_2 span P_2 Solutionlets calculate the dimension of S_2.pdf
armsnoida
 
Describe one exception to Mendelian inheritance In what year did Cha.pdf
Describe one exception to Mendelian inheritance  In what year did Cha.pdfDescribe one exception to Mendelian inheritance  In what year did Cha.pdf
Describe one exception to Mendelian inheritance In what year did Cha.pdf
armsnoida
 
Describe Norman’s 7 Stages of Action and Four Principles of Good Des.pdf
Describe Norman’s 7 Stages of Action and Four Principles of Good Des.pdfDescribe Norman’s 7 Stages of Action and Four Principles of Good Des.pdf
Describe Norman’s 7 Stages of Action and Four Principles of Good Des.pdf
armsnoida
 
Consider a system of two components, connected as shown in the diagr.pdf
Consider a system of two components, connected as shown in the diagr.pdfConsider a system of two components, connected as shown in the diagr.pdf
Consider a system of two components, connected as shown in the diagr.pdf
armsnoida
 
Bullying has become increasingly problematic for school aged childre.pdf
Bullying has become increasingly problematic for school aged childre.pdfBullying has become increasingly problematic for school aged childre.pdf
Bullying has become increasingly problematic for school aged childre.pdf
armsnoida
 
An experiment was conducted to determine whether a deficiency of carb.pdf
An experiment was conducted to determine whether a deficiency of carb.pdfAn experiment was conducted to determine whether a deficiency of carb.pdf
An experiment was conducted to determine whether a deficiency of carb.pdf
armsnoida
 
An abject is orbiting the Earth at 215 miles in altitude. It takes o.pdf
An abject is orbiting the Earth at 215 miles in altitude. It takes o.pdfAn abject is orbiting the Earth at 215 miles in altitude. It takes o.pdf
An abject is orbiting the Earth at 215 miles in altitude. It takes o.pdf
armsnoida
 
A protein that was isolated by a team of university scientists is su.pdf
A protein that was isolated by a team of university scientists is su.pdfA protein that was isolated by a team of university scientists is su.pdf
A protein that was isolated by a team of university scientists is su.pdf
armsnoida
 
3 Quiz Question 10 (of 11) If the cash is received before the related.pdf
3 Quiz Question 10 (of 11) If the cash is received before the related.pdf3 Quiz Question 10 (of 11) If the cash is received before the related.pdf
3 Quiz Question 10 (of 11) If the cash is received before the related.pdf
armsnoida
 

More from armsnoida (20)

Match appropriately. Best fit. stratum corneum papillary region ad.pdf
Match appropriately. Best fit.  stratum corneum  papillary region  ad.pdfMatch appropriately. Best fit.  stratum corneum  papillary region  ad.pdf
Match appropriately. Best fit. stratum corneum papillary region ad.pdf
 
In your own words does Enclave as a unit of security does it describe.pdf
In your own words does Enclave as a unit of security does it describe.pdfIn your own words does Enclave as a unit of security does it describe.pdf
In your own words does Enclave as a unit of security does it describe.pdf
 
I need help answering both these questionsQuestion 5 1. A dip.pdf
I need help answering both these questionsQuestion 5 1. A dip.pdfI need help answering both these questionsQuestion 5 1. A dip.pdf
I need help answering both these questionsQuestion 5 1. A dip.pdf
 
How would you investigate the question about the probability of matc.pdf
How would you investigate the question about the probability of matc.pdfHow would you investigate the question about the probability of matc.pdf
How would you investigate the question about the probability of matc.pdf
 
How did the issues of sectionalism reemerge in 1850, what was the pr.pdf
How did the issues of sectionalism reemerge in 1850, what was the pr.pdfHow did the issues of sectionalism reemerge in 1850, what was the pr.pdf
How did the issues of sectionalism reemerge in 1850, what was the pr.pdf
 
How is localization of Gap gene expression achieved in the Drosophil.pdf
How is localization of Gap gene expression achieved in the Drosophil.pdfHow is localization of Gap gene expression achieved in the Drosophil.pdf
How is localization of Gap gene expression achieved in the Drosophil.pdf
 
For the following ordinary differential equations, identify their de.pdf
For the following ordinary differential equations, identify their de.pdfFor the following ordinary differential equations, identify their de.pdf
For the following ordinary differential equations, identify their de.pdf
 
Find two models of incidence geometry, each with exactly four points.pdf
Find two models of incidence geometry, each with exactly four points.pdfFind two models of incidence geometry, each with exactly four points.pdf
Find two models of incidence geometry, each with exactly four points.pdf
 
Finish the following natural deduction proofs SolutionThe two .pdf
Finish the following natural deduction proofs SolutionThe two .pdfFinish the following natural deduction proofs SolutionThe two .pdf
Finish the following natural deduction proofs SolutionThe two .pdf
 
Find the most general f. Use C for the constant of the first anti-de.pdf
Find the most general f. Use C for the constant of the first anti-de.pdfFind the most general f. Use C for the constant of the first anti-de.pdf
Find the most general f. Use C for the constant of the first anti-de.pdf
 
Explain the concept of diaspora and distinguish between voluntary and.pdf
Explain the concept of diaspora and distinguish between voluntary and.pdfExplain the concept of diaspora and distinguish between voluntary and.pdf
Explain the concept of diaspora and distinguish between voluntary and.pdf
 
Does S_2 span P_2 Solutionlets calculate the dimension of S_2.pdf
Does S_2 span P_2 Solutionlets calculate the dimension of S_2.pdfDoes S_2 span P_2 Solutionlets calculate the dimension of S_2.pdf
Does S_2 span P_2 Solutionlets calculate the dimension of S_2.pdf
 
Describe one exception to Mendelian inheritance In what year did Cha.pdf
Describe one exception to Mendelian inheritance  In what year did Cha.pdfDescribe one exception to Mendelian inheritance  In what year did Cha.pdf
Describe one exception to Mendelian inheritance In what year did Cha.pdf
 
Describe Norman’s 7 Stages of Action and Four Principles of Good Des.pdf
Describe Norman’s 7 Stages of Action and Four Principles of Good Des.pdfDescribe Norman’s 7 Stages of Action and Four Principles of Good Des.pdf
Describe Norman’s 7 Stages of Action and Four Principles of Good Des.pdf
 
Consider a system of two components, connected as shown in the diagr.pdf
Consider a system of two components, connected as shown in the diagr.pdfConsider a system of two components, connected as shown in the diagr.pdf
Consider a system of two components, connected as shown in the diagr.pdf
 
Bullying has become increasingly problematic for school aged childre.pdf
Bullying has become increasingly problematic for school aged childre.pdfBullying has become increasingly problematic for school aged childre.pdf
Bullying has become increasingly problematic for school aged childre.pdf
 
An experiment was conducted to determine whether a deficiency of carb.pdf
An experiment was conducted to determine whether a deficiency of carb.pdfAn experiment was conducted to determine whether a deficiency of carb.pdf
An experiment was conducted to determine whether a deficiency of carb.pdf
 
An abject is orbiting the Earth at 215 miles in altitude. It takes o.pdf
An abject is orbiting the Earth at 215 miles in altitude. It takes o.pdfAn abject is orbiting the Earth at 215 miles in altitude. It takes o.pdf
An abject is orbiting the Earth at 215 miles in altitude. It takes o.pdf
 
A protein that was isolated by a team of university scientists is su.pdf
A protein that was isolated by a team of university scientists is su.pdfA protein that was isolated by a team of university scientists is su.pdf
A protein that was isolated by a team of university scientists is su.pdf
 
3 Quiz Question 10 (of 11) If the cash is received before the related.pdf
3 Quiz Question 10 (of 11) If the cash is received before the related.pdf3 Quiz Question 10 (of 11) If the cash is received before the related.pdf
3 Quiz Question 10 (of 11) If the cash is received before the related.pdf
 

Recently uploaded

Biological Screening of Herbal Drugs in detailed.
Biological Screening of Herbal Drugs in detailed.Biological Screening of Herbal Drugs in detailed.
Biological Screening of Herbal Drugs in detailed.
Ashokrao Mane college of Pharmacy Peth-Vadgaon
 
TESDA TM1 REVIEWER FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
TESDA TM1 REVIEWER  FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...TESDA TM1 REVIEWER  FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
TESDA TM1 REVIEWER FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
EugeneSaldivar
 
Embracing GenAI - A Strategic Imperative
Embracing GenAI - A Strategic ImperativeEmbracing GenAI - A Strategic Imperative
Embracing GenAI - A Strategic Imperative
Peter Windle
 
How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17
Celine George
 
Guidance_and_Counselling.pdf B.Ed. 4th Semester
Guidance_and_Counselling.pdf B.Ed. 4th SemesterGuidance_and_Counselling.pdf B.Ed. 4th Semester
Guidance_and_Counselling.pdf B.Ed. 4th Semester
Atul Kumar Singh
 
Synthetic Fiber Construction in lab .pptx
Synthetic Fiber Construction in lab .pptxSynthetic Fiber Construction in lab .pptx
Synthetic Fiber Construction in lab .pptx
Pavel ( NSTU)
 
How libraries can support authors with open access requirements for UKRI fund...
How libraries can support authors with open access requirements for UKRI fund...How libraries can support authors with open access requirements for UKRI fund...
How libraries can support authors with open access requirements for UKRI fund...
Jisc
 
Home assignment II on Spectroscopy 2024 Answers.pdf
Home assignment II on Spectroscopy 2024 Answers.pdfHome assignment II on Spectroscopy 2024 Answers.pdf
Home assignment II on Spectroscopy 2024 Answers.pdf
Tamralipta Mahavidyalaya
 
The basics of sentences session 5pptx.pptx
The basics of sentences session 5pptx.pptxThe basics of sentences session 5pptx.pptx
The basics of sentences session 5pptx.pptx
heathfieldcps1
 
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXXPhrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
MIRIAMSALINAS13
 
Overview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with MechanismOverview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with Mechanism
DeeptiGupta154
 
678020731-Sumas-y-Restas-Para-Colorear.pdf
678020731-Sumas-y-Restas-Para-Colorear.pdf678020731-Sumas-y-Restas-Para-Colorear.pdf
678020731-Sumas-y-Restas-Para-Colorear.pdf
CarlosHernanMontoyab2
 
"Protectable subject matters, Protection in biotechnology, Protection of othe...
"Protectable subject matters, Protection in biotechnology, Protection of othe..."Protectable subject matters, Protection in biotechnology, Protection of othe...
"Protectable subject matters, Protection in biotechnology, Protection of othe...
SACHIN R KONDAGURI
 
Thesis Statement for students diagnonsed withADHD.ppt
Thesis Statement for students diagnonsed withADHD.pptThesis Statement for students diagnonsed withADHD.ppt
Thesis Statement for students diagnonsed withADHD.ppt
EverAndrsGuerraGuerr
 
The Challenger.pdf DNHS Official Publication
The Challenger.pdf DNHS Official PublicationThe Challenger.pdf DNHS Official Publication
The Challenger.pdf DNHS Official Publication
Delapenabediema
 
The Accursed House by Émile Gaboriau.pptx
The Accursed House by Émile Gaboriau.pptxThe Accursed House by Émile Gaboriau.pptx
The Accursed House by Émile Gaboriau.pptx
DhatriParmar
 
Model Attribute Check Company Auto Property
Model Attribute  Check Company Auto PropertyModel Attribute  Check Company Auto Property
Model Attribute Check Company Auto Property
Celine George
 
The French Revolution Class 9 Study Material pdf free download
The French Revolution Class 9 Study Material pdf free downloadThe French Revolution Class 9 Study Material pdf free download
The French Revolution Class 9 Study Material pdf free download
Vivekanand Anglo Vedic Academy
 
A Strategic Approach: GenAI in Education
A Strategic Approach: GenAI in EducationA Strategic Approach: GenAI in Education
A Strategic Approach: GenAI in Education
Peter Windle
 
Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345
beazzy04
 

Recently uploaded (20)

Biological Screening of Herbal Drugs in detailed.
Biological Screening of Herbal Drugs in detailed.Biological Screening of Herbal Drugs in detailed.
Biological Screening of Herbal Drugs in detailed.
 
TESDA TM1 REVIEWER FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
TESDA TM1 REVIEWER  FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...TESDA TM1 REVIEWER  FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
TESDA TM1 REVIEWER FOR NATIONAL ASSESSMENT WRITTEN AND ORAL QUESTIONS WITH A...
 
Embracing GenAI - A Strategic Imperative
Embracing GenAI - A Strategic ImperativeEmbracing GenAI - A Strategic Imperative
Embracing GenAI - A Strategic Imperative
 
How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17How to Make a Field invisible in Odoo 17
How to Make a Field invisible in Odoo 17
 
Guidance_and_Counselling.pdf B.Ed. 4th Semester
Guidance_and_Counselling.pdf B.Ed. 4th SemesterGuidance_and_Counselling.pdf B.Ed. 4th Semester
Guidance_and_Counselling.pdf B.Ed. 4th Semester
 
Synthetic Fiber Construction in lab .pptx
Synthetic Fiber Construction in lab .pptxSynthetic Fiber Construction in lab .pptx
Synthetic Fiber Construction in lab .pptx
 
How libraries can support authors with open access requirements for UKRI fund...
How libraries can support authors with open access requirements for UKRI fund...How libraries can support authors with open access requirements for UKRI fund...
How libraries can support authors with open access requirements for UKRI fund...
 
Home assignment II on Spectroscopy 2024 Answers.pdf
Home assignment II on Spectroscopy 2024 Answers.pdfHome assignment II on Spectroscopy 2024 Answers.pdf
Home assignment II on Spectroscopy 2024 Answers.pdf
 
The basics of sentences session 5pptx.pptx
The basics of sentences session 5pptx.pptxThe basics of sentences session 5pptx.pptx
The basics of sentences session 5pptx.pptx
 
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXXPhrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
Phrasal Verbs.XXXXXXXXXXXXXXXXXXXXXXXXXX
 
Overview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with MechanismOverview on Edible Vaccine: Pros & Cons with Mechanism
Overview on Edible Vaccine: Pros & Cons with Mechanism
 
678020731-Sumas-y-Restas-Para-Colorear.pdf
678020731-Sumas-y-Restas-Para-Colorear.pdf678020731-Sumas-y-Restas-Para-Colorear.pdf
678020731-Sumas-y-Restas-Para-Colorear.pdf
 
"Protectable subject matters, Protection in biotechnology, Protection of othe...
"Protectable subject matters, Protection in biotechnology, Protection of othe..."Protectable subject matters, Protection in biotechnology, Protection of othe...
"Protectable subject matters, Protection in biotechnology, Protection of othe...
 
Thesis Statement for students diagnonsed withADHD.ppt
Thesis Statement for students diagnonsed withADHD.pptThesis Statement for students diagnonsed withADHD.ppt
Thesis Statement for students diagnonsed withADHD.ppt
 
The Challenger.pdf DNHS Official Publication
The Challenger.pdf DNHS Official PublicationThe Challenger.pdf DNHS Official Publication
The Challenger.pdf DNHS Official Publication
 
The Accursed House by Émile Gaboriau.pptx
The Accursed House by Émile Gaboriau.pptxThe Accursed House by Émile Gaboriau.pptx
The Accursed House by Émile Gaboriau.pptx
 
Model Attribute Check Company Auto Property
Model Attribute  Check Company Auto PropertyModel Attribute  Check Company Auto Property
Model Attribute Check Company Auto Property
 
The French Revolution Class 9 Study Material pdf free download
The French Revolution Class 9 Study Material pdf free downloadThe French Revolution Class 9 Study Material pdf free download
The French Revolution Class 9 Study Material pdf free download
 
A Strategic Approach: GenAI in Education
A Strategic Approach: GenAI in EducationA Strategic Approach: GenAI in Education
A Strategic Approach: GenAI in Education
 
Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345Sha'Carri Richardson Presentation 202345
Sha'Carri Richardson Presentation 202345
 

What are two possible causes of B12 deficiency Provide a detialed a.pdf

  • 1. What are two possible causes of B12 deficiency? Provide a detialed answer with literature review source. Solution Answer: Vitamin B12 is not synthesized by the body, and thus requires intake of animal foods rich in vitamin B12 or through supplements. Vitamin B12 helps in production of DNA and RNA, and works in concert with folic acid to make RBCs. Two possible causes of Vitamin B12 deficiency are: 1. Thinning of the stomach lining due to atrophic gastritis: Atrophic gastritis is often caused by the H. pylori. The bacterial infection frequently occurs during childhood and gets worse over time if it isn’t treated. Direct contact with the feces, vomit, or saliva of an infected person can spread the disease. It may also occur after eating food or drinking water that’s contaminated with the bacteria. When autoantibodies attack healthy stomach cells, autoimmune atrophic gastritis develops. These antibodies target the gastric juice producing stomach cells. These antibodies may also attack intrinsic factors, which are proteins released by stomach cells that help in vitamin B12 absorption. A lack of intrinsic factor results in pernicious anaemia, and low vitamin B12 levels in the body. (MLO Med Lab Obs. 2007 Feb;39(2):28, 30-1. Gut. 1964 Feb;5:27-37.) 2. Removed of part of the stomach or small intestine through surgery, including weight loss surgery: Bariatric surgery involves gut manipulation that alters the natural absorption of nutrients, thus nutritional deficiencies can develop. The most common deficiencies are vitamin B12, folate, zinc, iron, copper, calcium, and vitamin D and can lead to secondary problems, such as osteoporosis. Dietary supplementation are often given following surgery to avoid deficiency complications, although deficiency symptoms may be evident after months of surgery. Bariatic patients are at increased risk as their digestive have undergone alteration such that it interferes with the absorption of vitamins. (Curr Drug Metab. 2012 Nov; 13(9): 1345–1355. Pediatr Clin North Am. 2009 Oct; 56(5): 1105–1121.)