The Africa RISING West Africa Project began in 2011 with brainstorming meetings to plan farming systems intensification projects in Ghana and Mali. An inception workshop in 2012 established the research framework and approach. Africa RISING was launched as a 5-year research program with 3 regional projects in West Africa, Eastern and Southern Africa, and the Ethiopian Highlands. The goal is to create pathways for smallholders to move out of poverty through sustainable intensification. Field activities began in 2012 in Ghana and Mali, with research focusing on crop-livestock systems. Challenges implementing the first years included delays establishing baselines and integrating partner organizations.