This document discusses voluntary non-remunerated blood donation (VNRBD) and the goal of achieving 100% VNRBD globally by 2020. It notes that 52 countries currently collect less than 25% of their blood supply through voluntary donations. Challenges to achieving full voluntary donation include lack of funding and infrastructure for blood services. Solutions proposed are establishing a World Blood Donor Day, legislation to phase out paid donation, and public awareness campaigns to recruit more voluntary donors. Priorities for action include forming national advisory committees, training donor recruiters, and promoting collaboration between stakeholders.
Amazing Health Benefits of Blood DonationMedisys Kart
Donating blood regularly means we have to protect the liver from being damage which is generally caused by increase amount of iron in the body. Here are the amazing health benefits of blood donation.
Sustaining the HIV and AIDS Response in the Countries of the OECS: Regional I...HFG Project
In 2014, the six countries of the Organization of Eastern Caribbean States (OECS) of Antigua and Barbuda, Dominica, Grenada, St. Kitts and Nevis, St. Lucia and St. Vincent and the Grenadines developed HIV and AIDS Investment Case Briefs, with the support of USAID’s Health Finance and Governance (HFG) and Strengthening Health Outcomes through the Private Sector (SHOPS) projects. This document provides a summary of the findings of these briefs, which includes an analysis of the costs of HIV and AIDS programs that respond to the disease in the six countries, the resources that are available, the funding gaps, and the potential impact of different levels of investment in programming on the progression of the disease in the region.
Amazing Health Benefits of Blood DonationMedisys Kart
Donating blood regularly means we have to protect the liver from being damage which is generally caused by increase amount of iron in the body. Here are the amazing health benefits of blood donation.
Sustaining the HIV and AIDS Response in the Countries of the OECS: Regional I...HFG Project
In 2014, the six countries of the Organization of Eastern Caribbean States (OECS) of Antigua and Barbuda, Dominica, Grenada, St. Kitts and Nevis, St. Lucia and St. Vincent and the Grenadines developed HIV and AIDS Investment Case Briefs, with the support of USAID’s Health Finance and Governance (HFG) and Strengthening Health Outcomes through the Private Sector (SHOPS) projects. This document provides a summary of the findings of these briefs, which includes an analysis of the costs of HIV and AIDS programs that respond to the disease in the six countries, the resources that are available, the funding gaps, and the potential impact of different levels of investment in programming on the progression of the disease in the region.
How can you help others Be a Gift to the World through blood donation? Learn about the value of family and acquaintance blood donors (FAD) as a major source of potentially regular blood donors, particularly in resource-limited countries, and get ideas for blood donation projects from around the globe.
WHO Guidelines for Policymakers - World Hepatitis Day 2019Khubaib Samdani
WHO released guidelines for policymaker on World Hepatitis Day 2019. I am discussing two (1st and 10th) of those guidelines briefly in this presentation.
I presented this on webinar titled 'Session on Policy Reform' organized by Volunteer Force Against Hepatitis Transmission (VFAHT) on 22nd July, 2020.
You can watch the presentation here: https://www.facebook.com/vfaht.org/videos/889905641498191/
Top 10 messages for policymakers:
https://www.who.int/campaigns/world-hepatitis-day/2019/10-messages-for-policymakers
Additional Domestic Resources to Scale-up the HIV and TB Response in South Af...HFG Project
To tackle its substantial HIV and tuberculosis (TB) burdens, South Africa continues to rapidly scale up its response to both diseases. Over the past decade, the government of South Africa (GoSA) dramatically increased its financing for HIV and TB programs.
Rapid scale-up requires credible resource needs estimates to inform budget allocations. In the spring of 2015, South African officials and experts, in partnership with UNAIDS, finalized the detailed HIV and TB Investment Case that laid out the resource requirements for achieving the country’s coverage goals. Next came the complex task of translating the Investment Case’s findings into recommended budget allocations in South Africa’s Medium Term Expenditure Framework (MTEF), wherein the GoSA determines its budget plans for the next three financial years.
Through intensive engagement in July–September 2015, the USAID/PEPFAR-funded Health Finance and Governance Project (HFG) supported the GoSA National Treasury (NT) in its analysis of HIV and TB budget bids. Each year, NT solicits bids from other national departments for additional funding or to redistribute resources across departmental programs. In this case, the HFG team validated the National Department of Health (NDoH)’s bids against data from the HIV and TB Investment Case and advised both NT and NDoH on how to strengthen the submissions and prioritize investments given general fiscal constraints.
The National HIV Prevention Inventory provides the first, comprehensive inventory of HIV prevention efforts at the state and local levels in the United States. Based on a survey of 65 health departments, including all state and territorial jurisdictions and six U.S. cities, the Inventory is intended to offer a baseline picture of how HIV prevention is delivered across the country in an effort to provide policymakers, public health officials, community organizations, and others with a more in depth understanding of HIV prevention and the role played by health departments in its delivery.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
1. Salwa Hindawi
Professor of Haematology & Transfusion
Medicine
King Abdulaziz University, Jeddah
Saudi Arabia
Voluntary Non remunerated Blood
Donation (VNRBD)
Salwa Hindawi 2019
2. Introduction
In most developing countries 50-80% of supplied
blood is used for obstetrics emergencies
Worldwide, >100 million people sustain injuries each
year and >5 million die from violence and injury.
RTAs are the 2nd leading cause of death and a leading
cause of serious injury for both sexes aged 5–29y.
Uncontrolled bleeding accounts for >40% of trauma
related deaths.
Salwa Hindawi 2019
3. Introduction
Globally, up to 4 million people have been infected
with HIV by the transfusion of unsafe blood.
The prevalence of hepatitis B, hepatitis C and syphilis
in donated blood is still unacceptably high in many
developing countries.
Many countries lack policies, procedures or resources
for ensuring the safety of blood.
Salwa Hindawi 2019
4. Introduction
Blood transfusion saves lives, but the transfusion
of unsafe blood puts lives at risk because HIV,
hepatitis B, hepatitis C, syphilis, malaria and other
infections can be transmitted to the recipients
through transfusion.
The Fifty-eighth World Health Assembly
Resolution WHA28.7 2urged the development of
national blood services based on VNBD.
Salwa Hindawi 2019
5. Achieving 100% VNRBD Through:
WHO Global Consultation on 100% Voluntary Non-
Remunerated Donation of Blood and Blood Components, 9-11
June 2009, Melbourne, Australia
Launch of the WHO-IFRCS publication: Towards 100%
Voluntary Blood Donation: A Global Framework for Action
World Blood Donor Day 14 June 2009: WBDD global event to
be held in Australia
Theme 'Achievement of 100 per cent voluntary non-remunerated
donation of blood and blood components'
Salwa Hindawi 2019
6. Definition of VNRBD
Persons who give blood, plasma or other blood
components of their own free well and receive no
payment for it, either in the form of cash, or in
kind which could be considered as substitute for
money.
Small tokens, refreshments and reimbursements of
direct travel costs are compatible with voluntary,
non-remunerated blood donation.
Salwa Hindawi 2019
7. Global Blood Supply
Human Development Index (HDI)
High HDI
(n=62)
54.5 M (64%)
Medium HDI
(n=73)
29.7 M (35%)
Low HDI
(n=27)
1.2 M (1%)
High HDI Medium HDI Low HDI
WHO-BSI/GDBS 2006/07
Total Blood Collection: 85 millions (162 Countries)
8. Global Population and Blood Supply
24%
64%
67%
35%
9%
2%
0%
10%
20%
30%
40%
50%
60%
70%
%
High HDI Medium HDI Low HDI
% Population % Donations WHO-BSI/GDBS 2006/07
9. WB donations vs Apheresis , by HDI
category
0
10,000,000
20,000,000
30,000,000
40,000,000
50,000,000
60,000,000
Numberofdonations
High HDI Medium HDI Low HDI
HDI category
Whole Blood Apheresis
17.7%
2.2%
> 93% of the apheresis donations collected in developed countries
0.2%
WHO-BSI/GDBS 2006/07
10. Discard of blood
TTI
24%
Date expiry
28%
Faulty collection
15%
Storage/transport
problem
1%
Others
32%
WHO-BSI/GDBS 2006/07
3.3 million donations discarded
11. Types of Blood Donations, by HDI
93.7%
4.3%
2.0%
76.8%
22.0%
1.2%
69.2%
29.3%
1.5%
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
%
High HDI Medium HDI Low HDI
Voluntary non-remunerated Family/replacement Paid
54.6 million
1.45 billion
29.7 million
3.96 billion
1.2 million
0.52 billion
Donations
Populations
WHO-BSI/GDBS 2006/07
12. Percentage of voluntary NR blood donation, by HDI
13 30 9
6 14 5
6 11 2
6 5 1
6 8 4
35 14 8
0 10 20 30 40 50 60
No. of countries
<25%
25%-<50%
50%-<75%
75%-<90%
90%-<100%
100%
%ofvoluntarynonremunerateddonations
High HDI (n=72) Medium HDI (n=82) Low HDI (n=29)
57
18
52
WHO-BSI/GDBS 2006/07
13. 111 countries show↑ in number blood donations by
voluntary NR blood donors (2006/7 vs. 2004/5)
32 of these 111 countries (all these 32 countries are
developing or transitional countries) have shown
more than double the number of voluntary donations
as compared to 2004
11 countries report >10% increase in voluntary NR
blood donations in 2007, as compared to 2006
Type of Blood Donations
Salwa Hindawi 2019
14. 52 countries collect < 25% of their blood supplies
from voluntary NR blood donations
31 countries still report collecting paid donations in
2007, > 1 million in total
Type of Blood Donations
Salwa Hindawi 2019
15.
16. Vision and Mission
Achievement of 100% Voluntary Non-remunerated
Blood Donation Globally by 2020
Promote and support the establishment of effective
VNRBD programs to improve access to safe and
sufficient blood supplies
Provide guidance and support countries seeking to:
establish effective VNRBD programmes
phase out family/replacement blood donation
eliminate paid "donation"
Salwa Hindawi 2019
17. Challenges
Lack of political commitment and support, policy and
legislation.
Fragmentation, lack of structure, coordination and quality,
and low efficiency in blood services
Lack of adequate budget
absence of a comprehensive blood donor programme
inadequate financial resources and lack of trained human
resources
Inadequate infrastructure, facilities and system to provide
quality care to blood donors
Lack of outreach community programmes and effective
communication with potential blood donors
Salwa Hindawi 2019
18. Continuing Challenges
Considerable reliance on family replacement and paid donations in
many countries
High prevalence of TTIs in the some region and risk of transmission
through unsafe blood
Shrinking VNRB donor base
Balancing supply and safety in this globalised world
This leads to
Blood shortages, low donation rates, high discard rates
Low rates of voluntary blood donation
Lack of trust in the blood service
Salwa Hindawi 2019
19. Solutions
the establishment of an annual World Blood Donor Day, to
be celebrated on 14 June each year.
blood donor day should be an integral part of the national
blood donor recruitment programme.
to establish or strengthen systems for the recruitment and
retention of voluntary non remunerated blood donors and
the implementation of stringent criteria for donor selection.
Salwa Hindawi 2019
20. Solutions
to introduce legislation, where needed, to eliminate
paid blood donation except in limited circumstances of
medical necessity and, in such cases, to require
mention in the informed consent and to be agreed and
signed by the transfusion recipient.
to ensure the proper use of blood transfusion in
clinical practice so as to avoid abuse of blood
transfusion, which may result in a shortage of blood
and hence stimulate the need for paid
blood donation.
Salwa Hindawi 2019
21. Solutions
to support the full implementation of well-organized,
nationally coordinated and sustainable blood programs
with appropriate regulatory systems
INVITES private agencies to provide adequate funding for
initiatives to promote voluntary, non remunerated blood
donation.
Salwa Hindawi 2019
22. Priorities for action to achieve 100%
VNRBD:
1-Active National Advisory Committee:
A Panel of experts is needed in all countries to help in
development of national policies, and to follow up
their implementation.
2- Awareness Campaigns on regular bases to involve
people from the society and media to promote better
education and knowledge about voluntary blood
donation.
3- Training programs for donor recruiters to help in
develop needed skills for recruitment and donor
retention.
Salwa Hindawi 2019
23. Recommendations to all key stakeholders
To have an expert personal at WHO working office in
each country to advise and monitor the implementation
of WHO recommendations.
To promote collaboration and partnership at all levels
nationally and internationally.
To support financially all activities related to
development of 100% voluntary non- remunerated blood
donation.
Salwa Hindawi 2019
24. Conclusion
Safe blood comes from safe donor (volunteer non-
remounted donor) to have a safe donor we will need:
Adequate resources.
Mobile units.
Education materials.
Media coverage .
Total management for adequate safe blood supply.
Salwa Hindawi 2019
25. Who should join Donor recruitment
program?
Salwa Hindawi 2019
26. References:
WHO Global Consultation on 100% Voluntary
Non-Remunerated Donation of Blood and Blood
Components, 9-11 June 2009, Melbourne,
Australia
World Health Organisation official website.
Salwa Hindawi 2019
27. Saudi Society of Transfusion Medicine
(SSTM)
Please join us to help in upgrading and
improving blood transfusion services in the
Kingdom of Saudi Arabia.
Website:
www.sstm.org.sa
E-mail:
sstm_2009@hotmail.com
Salwa Hindawi 2019