Pravin U. Dugel, MD, David S. Boyer, MD, and Peter K. Kaiser, MD, prepared useful Practice Aids pertaining to neovascular AMD for this CME activity titled "Updates in Neovascular Age-Related Macular Degeneration: Improving Detection, Reducing the Burden of Treatment, and Optimizing Visual Outcomes." For the full presentation, monograph, complete CME information, and to apply for credit, please visit us at http://bit.ly/2LPfsMx. CME credit will be available until June 10, 2019.
Pravin U. Dugel, MD, David S. Boyer, MD, and Peter K. Kaiser, MD, prepared useful Practice Aids pertaining to neovascular AMD for this CME activity titled "Updates in Neovascular Age-Related Macular Degeneration: Improving Detection, Reducing the Burden of Treatment, and Optimizing Visual Outcomes." For the full presentation, monograph, complete CME information, and to apply for credit, please visit us at http://bit.ly/2LPfsMx. CME credit will be available until June 10, 2019.
Clinical trials established in 2005 the efficacy of Ranibizumab (Lucentis, Genentech) for the treatment of neovascular age-related macular degeneration (wetAMD), the leading cause of legal blindness in the United States.This disease is affecting people over the age of 65 with a prevalence of 1.6 million and 200000 new cases per year in the USA .While awaiting approval for ranibizumab from the Food and Drug Administration, ophthalmologists began treating neovascular AMD with off-label use of bevacizumab (Avastin, Genentech), since the drug had a target specificity similar to that of ranibizumab and was available at low cost for about 50$ per monthly injection Vs 1950$ for Lucentis monthly injection.
Ranibizumab received the FDA approuval in 2006 to treat specifically the wetAMD,there was a huge debate about the cost effectiveness and the reimbursement of Lucentis in comparaison with Avastin for treating the eye disease.
This paper explores the dilemma from different angles.First,it make the emphasize on the need of realizing a head to head comparative study between the two drugs and the means to finance and to launch this study since many roadblocks have been identified.
Then, it explores and analyzes the Genentech reaction facing this problem and their strategy to emphasize on the higher risk of death with Avastin, as compared to Lucentis in one hand and in the other hand their strategy to extend the ophthalmologic indications for Lucentis, including diabetic macula edema (DME).
Finally it explores what value should be put on safety in health technology assessments HTAs by developing that we can’t just consider the dollar value of medicine alone but we need to consider the cost of adverse events caused by the treatment and the cost of living with these adverse events
Crown Medical Research and Pharmaceutical Sciences College of Canada.
Achieve your career goals in a short period of time with a very competitive education and get Canadian experience with the highest quality of supervised training.
Crown Medical Research and Pharmaceutical Sciences College of Canada offers opportunities to expand your experience beyond the classroom and support them with guidance on career opportunities.
Our professors, consultants, and course developers are recognized leaders in professional development and training in the field of pharmaceutical, natural health products, quality assurance and quality control, regulatory affairs and submissions, pharmacovigilance and drug safety reporting, clinical research, cosmetics, food sciences, biopharmaceutical, and health care policy and services management.
We strive to continuously evolve and expand our programs in an attempt to respond effectively to changing technologies and workforce demands in the industry. It is with this strategy that our programs will prepare our learners for their future.
When attending our college, you will be exposed to highly qualified professionals and professors as well as students with diverse backgrounds and proven professional abilities seeking to improve their skill set and employment outlook.
We are located at Richmond Hill, in the Greater Toronto Area, that is one of the 3 biggest financial and social center in North America. This gives learners access to the head quarters of many industries and to be exposed to personal, and professional growth opportunities.
Our college offers academic counseling program through one-on-one meetings with professors and collaborators and we offer faculty-mentoring program to assist students in improving their learning and working strategies for reaching faster their career goals.
When you are considering to enroll in a certificate course offered by our college, please explore the program information on the website and contact us for a one-on-one mentoring meeting, to visit the campus, and to get a career consultation at any time. Our intensive courses start every month and our learners can start their program with us at any time during the year.
A Systematic Comparison of Spectral-Domain Optical Coherence Tomography and F...John Redaelli
Ophthalmology - Sept. 2011 - A Systematic Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Patients with Geographic Atrophy
Presentation of Dr. Philipp Hagen and Dr. Detlev Breyer on the Impact of Biomechanical Indices on Visual Outcome up to Five Years after Refractive Lenticule Extraction (ReLEx) SMILE. ESCRS, Vienna 2018.
A Comparative Study of Age Related Macular Degeneration In Relation To SD-OCT...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Clinical trials established in 2005 the efficacy of Ranibizumab (Lucentis, Genentech) for the treatment of neovascular age-related macular degeneration (wetAMD), the leading cause of legal blindness in the United States.This disease is affecting people over the age of 65 with a prevalence of 1.6 million and 200000 new cases per year in the USA .While awaiting approval for ranibizumab from the Food and Drug Administration, ophthalmologists began treating neovascular AMD with off-label use of bevacizumab (Avastin, Genentech), since the drug had a target specificity similar to that of ranibizumab and was available at low cost for about 50$ per monthly injection Vs 1950$ for Lucentis monthly injection.
Ranibizumab received the FDA approuval in 2006 to treat specifically the wetAMD,there was a huge debate about the cost effectiveness and the reimbursement of Lucentis in comparaison with Avastin for treating the eye disease.
This paper explores the dilemma from different angles.First,it make the emphasize on the need of realizing a head to head comparative study between the two drugs and the means to finance and to launch this study since many roadblocks have been identified.
Then, it explores and analyzes the Genentech reaction facing this problem and their strategy to emphasize on the higher risk of death with Avastin, as compared to Lucentis in one hand and in the other hand their strategy to extend the ophthalmologic indications for Lucentis, including diabetic macula edema (DME).
Finally it explores what value should be put on safety in health technology assessments HTAs by developing that we can’t just consider the dollar value of medicine alone but we need to consider the cost of adverse events caused by the treatment and the cost of living with these adverse events
Crown Medical Research and Pharmaceutical Sciences College of Canada.
Achieve your career goals in a short period of time with a very competitive education and get Canadian experience with the highest quality of supervised training.
Crown Medical Research and Pharmaceutical Sciences College of Canada offers opportunities to expand your experience beyond the classroom and support them with guidance on career opportunities.
Our professors, consultants, and course developers are recognized leaders in professional development and training in the field of pharmaceutical, natural health products, quality assurance and quality control, regulatory affairs and submissions, pharmacovigilance and drug safety reporting, clinical research, cosmetics, food sciences, biopharmaceutical, and health care policy and services management.
We strive to continuously evolve and expand our programs in an attempt to respond effectively to changing technologies and workforce demands in the industry. It is with this strategy that our programs will prepare our learners for their future.
When attending our college, you will be exposed to highly qualified professionals and professors as well as students with diverse backgrounds and proven professional abilities seeking to improve their skill set and employment outlook.
We are located at Richmond Hill, in the Greater Toronto Area, that is one of the 3 biggest financial and social center in North America. This gives learners access to the head quarters of many industries and to be exposed to personal, and professional growth opportunities.
Our college offers academic counseling program through one-on-one meetings with professors and collaborators and we offer faculty-mentoring program to assist students in improving their learning and working strategies for reaching faster their career goals.
When you are considering to enroll in a certificate course offered by our college, please explore the program information on the website and contact us for a one-on-one mentoring meeting, to visit the campus, and to get a career consultation at any time. Our intensive courses start every month and our learners can start their program with us at any time during the year.
A Systematic Comparison of Spectral-Domain Optical Coherence Tomography and F...John Redaelli
Ophthalmology - Sept. 2011 - A Systematic Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Patients with Geographic Atrophy
Presentation of Dr. Philipp Hagen and Dr. Detlev Breyer on the Impact of Biomechanical Indices on Visual Outcome up to Five Years after Refractive Lenticule Extraction (ReLEx) SMILE. ESCRS, Vienna 2018.
A Comparative Study of Age Related Macular Degeneration In Relation To SD-OCT...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Overview of glaucoma from an engineering perspective for ophthalmologic technology used for diagnosis, disease management and eventually for personalized medicine.
External download link: https://www.dropbox.com/s/i7qmd5ecj8c247x/glaucoma_overview.pdf?dl=0
Electrophysiological assessment of optic neuritis: is there still a roleClare Fraser
Visual evoked potentials were once in the diagnostic criteria for Multiple Sclerosis, but have been left off the most recent criteria. However, there are newer techniques available which are still invaluable in the diagnosis of optic neuritis and its common mimics.
Ocular Manifestations In Sickle Cell Disease – A Preventable Cause Of Blindness?iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Purpose: To evaluate the corneal volume (CV) before and after Ferrara intrastromal corneal ring segments (ICRS) implantation and its influence in clinical outcomes in keratoconus patients.
Discussion of clinical approach to typical (demyelnating) and atypical optic neuritis (immune/inflammatory/infectious) optic neuritis with evidence-based review.
Target: Ophthalmologists/Neurologists
April 2019 . Cataracts secondary to intraocular diseases are complicated cata...Vinitkumar MJ
DEMOGRAPHIC PROFILES AND AETIOLOGY OF COMPLICATED CATARACTS: A HOSPITAL BASED STUDY.
Aim: To study demographic profiles and aetiology of complicated cataracts in patients presenting to the Out-Patient Department of B. P. Koirala Lions Centre for Ophthalmic Studies (BPKLCOS).
Similar to Visual Outcome After Cataract Surgery In Patients With Retinitis Pigmentosa. (20)
Oct : Noninvasive Method To Monitor Effectivity Of Chemotherapy In Lung Car...Dr. Jagannath Boramani
Dr. Prajakta Patil(Fellow), Dr. Sarvesh Tiwari(Consultant), Dr. Gaurav Shah(Honorary Consultant), Dr. Anand Subramanyam (Head Of The Department), K. B. H. Bachooali Ophthalmic And Ent Hospital,Parel,Mumbai
Feeding plate for a newborn with Cleft Palate.pptxSatvikaPrasad
A feeding plate is a prosthetic device used for newborns with a cleft palate to assist in feeding and improve nutrition intake. From a prosthodontic perspective, this plate acts as a barrier between the oral and nasal cavities, facilitating effective sucking and swallowing by providing a more normal anatomical structure. It helps to prevent milk from entering the nasal passage, thereby reducing the risk of aspiration and enhancing the infant's ability to feed efficiently. The feeding plate also aids in the development of the oral muscles and can contribute to better growth and weight gain. Its custom fabrication and proper fitting by a prosthodontist are crucial for ensuring comfort and functionality, as well as for minimizing potential complications. Early intervention with a feeding plate can significantly improve the quality of life for both the infant and the parents.
Under Pressure : Kenneth Kruk's StrategyKenneth Kruk
Kenneth Kruk's story of transforming challenges into opportunities by leading successful medical record transitions and bridging scientific knowledge gaps during COVID-19.
INFECTION OF THE BRAIN -ENCEPHALITIS ( PPT)blessyjannu21
Neurological system includes brain and spinal cord. It plays an important role in functioning of our body. Encephalitis is the inflammation of the brain. Causes include viral infections, infections from insect bites or an autoimmune reaction that affects the brain. It can be life-threatening or cause long-term complications. Treatment varies, but most people require hospitalization so they can receive intensive treatment, including life support.
Dr. David Greene R3 stem cell Breakthroughs: Stem Cell Therapy in CardiologyR3 Stem Cell
Dr. David Greene, founder and CEO of R3 Stem Cell, is at the forefront of groundbreaking research in the field of cardiology, focusing on the transformative potential of stem cell therapy. His latest work emphasizes innovative approaches to treating heart disease, aiming to repair damaged heart tissue and improve heart function through the use of advanced stem cell techniques. This research promises not only to enhance the quality of life for patients with chronic heart conditions but also to pave the way for new, more effective treatments. Dr. Greene's work is notable for its focus on safety, efficacy, and the potential to significantly reduce the need for invasive surgeries and long-term medication, positioning stem cell therapy as a key player in the future of cardiac care.
Rate Controlled Drug Delivery Systems, Activation Modulated Drug Delivery Systems, Mechanically activated, pH activated, Enzyme activated, Osmotic activated Drug Delivery Systems, Feedback regulated Drug Delivery Systems systems are discussed here.
DECODING THE RISKS - ALCOHOL, TOBACCO & DRUGS.pdfDr Rachana Gujar
Introduction: Substance use education is crucial due to its prevalence and societal impact.
Alcohol Use: Immediate and long-term risks include impaired judgment, health issues, and social consequences.
Tobacco Use: Immediate effects include increased heart rate, while long-term risks encompass cancer and heart disease.
Drug Use: Risks vary depending on the drug type, including health and psychological implications.
Prevention Strategies: Education, healthy coping mechanisms, community support, and policies are vital in preventing substance use.
Harm Reduction Strategies: Safe use practices, medication-assisted treatment, and naloxone availability aim to reduce harm.
Seeking Help for Addiction: Recognizing signs, available treatments, support systems, and resources are essential for recovery.
Personal Stories: Real stories of recovery emphasize hope and resilience.
Interactive Q&A: Engage the audience and encourage discussion.
Conclusion: Recap key points and emphasize the importance of awareness, prevention, and seeking help.
Resources: Provide contact information and links for further support.
International Cancer Survivors Day is celebrated during June, placing the spotlight not only on cancer survivors, but also their caregivers.
CANSA has compiled a list of tips and guidelines of support:
https://cansa.org.za/who-cares-for-cancer-patients-caregivers/
LGBTQ+ Adults: Unique Opportunities and Inclusive Approaches to CareVITASAuthor
This webinar helps clinicians understand the unique healthcare needs of the LGBTQ+ community, primarily in relation to end-of-life care. Topics include social and cultural background and challenges, healthcare disparities, advanced care planning, and strategies for reaching the community and improving quality of care.
Chandrima Spa Ajman is one of the leading Massage Center in Ajman, which is open 24 hours exclusively for men. Being one of the most affordable Spa in Ajman, we offer Body to Body massage, Kerala Massage, Malayali Massage, Indian Massage, Pakistani Massage Russian massage, Thai massage, Swedish massage, Hot Stone Massage, Deep Tissue Massage, and many more. Indulge in the ultimate massage experience and book your appointment today. We are confident that you will leave our Massage spa feeling refreshed, rejuvenated, and ready to take on the world.
Visit : https://massagespaajman.com/
Call : 052 987 1315
We are one of the top Massage Spa Ajman Our highly skilled, experienced, and certified massage therapists from different corners of the world are committed to serving you with a soothing and relaxing experience. Luxuriate yourself at our spas in Sharjah and Ajman, which are indeed enriched with an ambiance of relaxation and tranquility. We could confidently claim that we are one of the most affordable Spa Ajman and Sharjah as well, where you can book the massage session of your choice for just 99 AED at any time as we are open 24 hours a day, 7 days a week.
Visit : https://massagespaajman.com/
Call : 052 987 1315
Visual Outcome After Cataract Surgery In Patients With Retinitis Pigmentosa.
1. Dr. Narayan S. Alane
Dr. Mehul A. Shah
Dr. Shreya M. Shah
2. Cataract is a recognized complication of all types of retinitis
pigmentosa especially posterior sub-capsular lens opacity
which occurs at a relatively younger age, which may be
combined with a restricted visual field causing significant visual
disturbance.
Glare is a major symptom and the patient may require surgery at
a younger age.
3. Apart from the general risks of cataract surgery, there are
specific additional risk factors2 that may result in
decreased visual outcome after cataract extraction in the
presence of RP namely,
1. The zonules are usually fragile in RP.
2. Posterior capsular opacificaton and anterior capsular
contraction are more aggressive in the presence of RP.
4. To study visual outcome after cataract surgery in retinitis
pigmentosa(RP) patients
To study relation of visual outcome with
-age of the patient,
-type of cataract,
-type of cataract surgery done.
5. We retrospectively reviewed the database in a standard
pretested format of consecutive series of 52 eyes with
RP who underwent cataract surgery. The changes in
visual outcome were measured and data analysed by
SPSS 23.
6. The preoperative BCVA was < 6/ 60 in 94% of patients. The
BCVA improved after cataract surgery from ≥6/18 in 45.2%
(P < 0.001). But final BCVA did not improve in 28 eyes
(53.8%).
The preoperative & final BCVA were significantly
correlated; final BCVA improved in the less advanced RP
group .
7. The final BCVA was statistically not related to age
(P<0.096), type of cataract (P<0.691), age at which
cataract surgery done (P<0.015) or gender
(P<0.317). 3.8% patients have secondary glaucoma.
8. Age of the patient No. of patients Percentage
21 to 30 3 5.8
31 to 40 12 23.1
41 to 50 15 28.8
51 to 6o 12 23.1
61 to 70 9 17.3
71 to 80 1 1.9
Total 52 100
10. Type of RP Frequency Percentage
Typical 50 96.2
Atypical 2 3.8
Glaucoma Frequency Percentage
Present 4 7.7
Abscent 48 92.3
11. Vision Type of surgery Percentage
Phaco+IOL SICS+IOL
< 1/60 3 16 36.5
1/60 to 3/60 0 9 17.3
4/60 to 6/36 2 10 23.1
6/24 to 6/18 1 0 1.9
6/12 to 6/9 4 2 11.5
6/6 to 6/5 1 4 9.6
Total 11 41 100
12. Final BCVA is improved in approximately half of the
eyes after cataract surgery in patients with retinitis
pigmentosa.
Final BCVA was better after phaco+IOL as compared
to after SICS+IOL.
THANK YOU...