Visual Axis Deprivation Amblyopia results from prolonged obstruction of the visual axis in one eye during childhood. It is the least common but most severe type of amblyopia. Prolonged monocular conditions like congenital cataract, ptosis, or corneal opacity before age 6 can cause severe visual loss. Treatment involves removing any obstructions, refractive correction, and occluding the good eye to encourage use of the amblyopic eye. Amblyopia affects 1-5% of the population in developed countries and 1-4% in India. Earlier onset and longer duration of obstruction lead to greater visual impairment.