Final presentation for the class of Toxicology of Natural Sourced Medicine (EMK Lui)
March 31 st.
If you are going to use this presentation, please, give credit to our work ¬¬U.
38 experts on bpa panel consensus statement. effects in animals and potential...ricguer
Un conjunto de 38 prestigiados científicos de todo el mundo alertan sobre el potencial nocivo y los impactos de exposición al Bisphenol A para la salud humana.
Lecture proposes a philosophical synthesis of the key concepts of the alcohol addiction neuroscience (the anhedonia hypothesis, the want-like system, the incentive salience hypothesis) and psychology (the rational choice model). As a core component the experience is reconstructed to become habitual during subsequent alcohol misuse. The existential phenomenology (Ludwig Binswanger) interpretation is provided.
KEY HYPOTHESIS
The addictive intake of alcohol and other narcotic drugs forms a simple snippet of code that circumvents the physiological paths of the tricky' reward system into discerning behavioral patterns to achieve some useful aims.
A core component of this presentation is alcohol experience. We tried to consider it as a whole, to describe its fluidity as some totality and uniqueness at the same time. We have found that this alcohol experience should not be fully integrated into existing or airy future theories corrected by rigid methods or firm recommendations. The disclosure of air alcohol experience has accomplished the special philosophical mission. This approach has derived much of its inspiration by the spirit of classical psychoanalysis, which was first in the field of expertise corresponding pathological experience.
The peripeteia of addictive behavior offers such an example of aspiration to a momentary pleasure that leads to new troubles proceeding through a sequence of stages beginning with a deeper dividing of the Self, social stigmatization, social death and, finally, biological death. Thus, we face philosophical challenges. Internally, alcohol may be ideating as a rapid elevator to the Wonderland of dream, happiness, pleasure or calmness. But the best we can say here is that these wishes, wanting and liking act as certain hacked codes for both the mind and the neurobiology of the brain.
This presentation has shown that, although the brain impulses either trigger or support alcohol addiction, we can never confine mental activities to certain physical and chemical processes in a human brain, nor can we reduce our life to mere physiological reactions, behavior models and psychological affects.
Anticonvulsant and toxicity effects of ethanolic extract of Thevetia Peruvian...Premier Publishers
Epilepsy is a neurologic condition due to disordered firing of brain neurons characterised by seizures. Most currently available antiepileptic drugs are synthetic and do not offer a complete cure yet with devastating side effects. Studies have shown that extracts from certain plants can produce anticonvulsant effects and may, therefore be useful against epileptic seizures. To investigate anticonvulsant effect of ethanolic extract of the leaves of Thevetia peruviana on chemically induced seizures in Wister rats. Leaves of T. peruviana were pulverised and extracted with ethanol. Graded doses of the ethanolic extract were used to test for the anticonvulsant effect of the extract using pentylenetetrazole model of seizures in rats. Acute toxicity testing and phytochemical analysis were done using Lorke’s method. Graded doses of T. peruviana leaf extract significantly delayed onset of seizures. They protected animals from death due to pentylenetetrazole-induced tonic seizures. There was no death up to 3000mg/kg. The extract was found to be rich in essential oils, flavonoids, alkaloid, phenols, proteins and resins. The ethanolic extract of the leaves of T. peruviana contains compounds with anticonvulsant effects since it protected the animals from death and delayed the onset of seizures produced by pentylenetetrazole and that is relatively safe.
An Integrative Approach to Environmental Intolerances, Multiple Chemical Sens...v2zq
An Integrative Approach to Environmental Intolerances, Multiple Chemical Sensitivity & Related Illnesses - Resources for Healthy Children www.scribd.com/doc/254613619 - For more information, Please see Organic Edible Schoolyards & Gardening with Children www.scribd.com/doc/254613963 - Gardening with Volcanic Rock Dust www.scribd.com/doc/254613846 - Double Food Production from your School Garden with Organic Tech www.scribd.com/doc/254613765 - Free School Gardening Art Posters www.scribd.com/doc/254613694 - Increase Food Production with Companion Planting in your School Garden www.scribd.com/doc/254609890 - Healthy Foods Dramatically Improves Student Academic Success www.scribd.com/doc/254613619 - City Chickens for your Organic School Garden www.scribd.com/doc/254613553 - Huerto Ecológico, Tecnologías Sostenibles, Agricultura Organica www.scribd.com/doc/254613494 - Simple Square Foot Gardening for Schools - Teacher Guide www.scribd.com/doc/254613410 - Free Organic Gardening Publications www.scribd.com/doc/254609890 ~
Homeopathy—quackery or a key to the future of medicine?home
When cholera first invaded Europe in 1831, the
mortality throughout Europe was generally between
40% and 60%. To the surprise of many, mortality
rates reported by homeopathic physicians was generally
below 10%, and commonly under 4%. Let me
present two typical cholera reports, which have a
stamp of officialdom. The first one comes from the
territory of Raab in Hungary where in 1831 a
Dr Joseph Bakody treated 223 patients with mild to
severe cholera, 14 of which were in a state of collapse .
He lost a total of 8 patients, a mortality of 3.6%. A
similar situation occurred in Cincinnati in 1849. The
Board of Health issued an order calling for physicians
to report all cases of cholera. Reports of a high
mortality rate were received by the Board from the city
hospital and allopathic physicians. However, six
homeopathic physicians attracted national attention
when they reported not a single death out of their first
350 cases of cholera. Two of these homeopathic
physicians, Dr Pulte and Ehrmann would eventually
report treating 2646 cases with 35 deaths, or a
mortality rate of 1.3%. Allopaths reported fatal
outcomes in about 50% of their cases.
Jacques Benveniste - A TRUE LEGEND AMONG MYTHSAnton Fedorenko
The above presented materials stand as a foundation for the justification of Jacques Benveniste and his research discoveries within the fields of biological and physical properties of water and the transfer of signals from biologically active substances are actual and attested. The implications of this natural phenomena have vast applications in multiple areas of human activity; and in particular, already are used in healthcare.
Jacques Benveniste The Outstanding French Scientist, was far ahead of his time and has made one of the greatest scientific breakthroughs in recorded history.
In the visage of our beloved science, the time is now upon us to restore justice by giving tribute to a man who has devoted himself wholeheartedly and suffered for his beliefs. Please join us in our righteous efforts by signing onto our international initiative group. Our main initiative is the restoration of the honest name Jacques Benveniste.
Basic research in homoeopathy and ultra high dilution Department of Agricultu...DrAnkit Srivastav
Basic research in homoeopathy and ultra high dilution Department of Agricultural Science, University of Bologna, Italy Department of Pathology and Diagnostics, University of Verona, Italy
Short-Term Effects of Repeated Olfactory Administration of Homeopathic Sulphu...Francisco Navarro
Short-Term Effects of Repeated Olfactory Administration of
Homeopathic Sulphur or Pulsatilla on Electroencephalographic
Alpha Power in Healthy Young Adults
38 experts on bpa panel consensus statement. effects in animals and potential...ricguer
Un conjunto de 38 prestigiados científicos de todo el mundo alertan sobre el potencial nocivo y los impactos de exposición al Bisphenol A para la salud humana.
Lecture proposes a philosophical synthesis of the key concepts of the alcohol addiction neuroscience (the anhedonia hypothesis, the want-like system, the incentive salience hypothesis) and psychology (the rational choice model). As a core component the experience is reconstructed to become habitual during subsequent alcohol misuse. The existential phenomenology (Ludwig Binswanger) interpretation is provided.
KEY HYPOTHESIS
The addictive intake of alcohol and other narcotic drugs forms a simple snippet of code that circumvents the physiological paths of the tricky' reward system into discerning behavioral patterns to achieve some useful aims.
A core component of this presentation is alcohol experience. We tried to consider it as a whole, to describe its fluidity as some totality and uniqueness at the same time. We have found that this alcohol experience should not be fully integrated into existing or airy future theories corrected by rigid methods or firm recommendations. The disclosure of air alcohol experience has accomplished the special philosophical mission. This approach has derived much of its inspiration by the spirit of classical psychoanalysis, which was first in the field of expertise corresponding pathological experience.
The peripeteia of addictive behavior offers such an example of aspiration to a momentary pleasure that leads to new troubles proceeding through a sequence of stages beginning with a deeper dividing of the Self, social stigmatization, social death and, finally, biological death. Thus, we face philosophical challenges. Internally, alcohol may be ideating as a rapid elevator to the Wonderland of dream, happiness, pleasure or calmness. But the best we can say here is that these wishes, wanting and liking act as certain hacked codes for both the mind and the neurobiology of the brain.
This presentation has shown that, although the brain impulses either trigger or support alcohol addiction, we can never confine mental activities to certain physical and chemical processes in a human brain, nor can we reduce our life to mere physiological reactions, behavior models and psychological affects.
Anticonvulsant and toxicity effects of ethanolic extract of Thevetia Peruvian...Premier Publishers
Epilepsy is a neurologic condition due to disordered firing of brain neurons characterised by seizures. Most currently available antiepileptic drugs are synthetic and do not offer a complete cure yet with devastating side effects. Studies have shown that extracts from certain plants can produce anticonvulsant effects and may, therefore be useful against epileptic seizures. To investigate anticonvulsant effect of ethanolic extract of the leaves of Thevetia peruviana on chemically induced seizures in Wister rats. Leaves of T. peruviana were pulverised and extracted with ethanol. Graded doses of the ethanolic extract were used to test for the anticonvulsant effect of the extract using pentylenetetrazole model of seizures in rats. Acute toxicity testing and phytochemical analysis were done using Lorke’s method. Graded doses of T. peruviana leaf extract significantly delayed onset of seizures. They protected animals from death due to pentylenetetrazole-induced tonic seizures. There was no death up to 3000mg/kg. The extract was found to be rich in essential oils, flavonoids, alkaloid, phenols, proteins and resins. The ethanolic extract of the leaves of T. peruviana contains compounds with anticonvulsant effects since it protected the animals from death and delayed the onset of seizures produced by pentylenetetrazole and that is relatively safe.
An Integrative Approach to Environmental Intolerances, Multiple Chemical Sens...v2zq
An Integrative Approach to Environmental Intolerances, Multiple Chemical Sensitivity & Related Illnesses - Resources for Healthy Children www.scribd.com/doc/254613619 - For more information, Please see Organic Edible Schoolyards & Gardening with Children www.scribd.com/doc/254613963 - Gardening with Volcanic Rock Dust www.scribd.com/doc/254613846 - Double Food Production from your School Garden with Organic Tech www.scribd.com/doc/254613765 - Free School Gardening Art Posters www.scribd.com/doc/254613694 - Increase Food Production with Companion Planting in your School Garden www.scribd.com/doc/254609890 - Healthy Foods Dramatically Improves Student Academic Success www.scribd.com/doc/254613619 - City Chickens for your Organic School Garden www.scribd.com/doc/254613553 - Huerto Ecológico, Tecnologías Sostenibles, Agricultura Organica www.scribd.com/doc/254613494 - Simple Square Foot Gardening for Schools - Teacher Guide www.scribd.com/doc/254613410 - Free Organic Gardening Publications www.scribd.com/doc/254609890 ~
Homeopathy—quackery or a key to the future of medicine?home
When cholera first invaded Europe in 1831, the
mortality throughout Europe was generally between
40% and 60%. To the surprise of many, mortality
rates reported by homeopathic physicians was generally
below 10%, and commonly under 4%. Let me
present two typical cholera reports, which have a
stamp of officialdom. The first one comes from the
territory of Raab in Hungary where in 1831 a
Dr Joseph Bakody treated 223 patients with mild to
severe cholera, 14 of which were in a state of collapse .
He lost a total of 8 patients, a mortality of 3.6%. A
similar situation occurred in Cincinnati in 1849. The
Board of Health issued an order calling for physicians
to report all cases of cholera. Reports of a high
mortality rate were received by the Board from the city
hospital and allopathic physicians. However, six
homeopathic physicians attracted national attention
when they reported not a single death out of their first
350 cases of cholera. Two of these homeopathic
physicians, Dr Pulte and Ehrmann would eventually
report treating 2646 cases with 35 deaths, or a
mortality rate of 1.3%. Allopaths reported fatal
outcomes in about 50% of their cases.
Jacques Benveniste - A TRUE LEGEND AMONG MYTHSAnton Fedorenko
The above presented materials stand as a foundation for the justification of Jacques Benveniste and his research discoveries within the fields of biological and physical properties of water and the transfer of signals from biologically active substances are actual and attested. The implications of this natural phenomena have vast applications in multiple areas of human activity; and in particular, already are used in healthcare.
Jacques Benveniste The Outstanding French Scientist, was far ahead of his time and has made one of the greatest scientific breakthroughs in recorded history.
In the visage of our beloved science, the time is now upon us to restore justice by giving tribute to a man who has devoted himself wholeheartedly and suffered for his beliefs. Please join us in our righteous efforts by signing onto our international initiative group. Our main initiative is the restoration of the honest name Jacques Benveniste.
Basic research in homoeopathy and ultra high dilution Department of Agricultu...DrAnkit Srivastav
Basic research in homoeopathy and ultra high dilution Department of Agricultural Science, University of Bologna, Italy Department of Pathology and Diagnostics, University of Verona, Italy
Short-Term Effects of Repeated Olfactory Administration of Homeopathic Sulphu...Francisco Navarro
Short-Term Effects of Repeated Olfactory Administration of
Homeopathic Sulphur or Pulsatilla on Electroencephalographic
Alpha Power in Healthy Young Adults
Cell sensitivity, non-linearity and inverse effectshome
The classic homeopathic method of drug discovery was
originally based on careful observation of symptoms
because at that time there was no knowledge of the ‘intimate
nature’ of disease processes and of pharmacodynamic
actions. The conceptual model presented here
helps us to understand that the two perspectives e ‘holistic’,
based on symptoms of the whole person and ‘reductionistic’,
based on cellular and molecular changes e are
not in contrast but have the same heuristic connotation.
With the introduction of modern ‘omics’ techniques,
the knowledge basis of homeopathic drug actions on
healthy and sick people can be deepened to the molecular
level.
Tinciones En Histología: Microscopia Electrónica - Hidróxido de Plomo AlcalinoIsbosphere
Tinción de contraste para Microscopia Electrónica.
Universidad Nacional Autónoma de México
Facultad de Estudios Superiores Cuautitlán
Laboratorio de Morfofisiología 2602
Nuñez Luna Isboset Gabriel
Gama Brambila Rodrigo
Dominguez Villa Francisco
Grupo 2602
Catabolismo de carbohidratos.
Facultad de Estudios Superiores Cuautitlan.
Bioquimica del Trombocito y el LeucocitoIsbosphere
Universidad Nacional Autónoma de México.
Facultad de Estudios Superiores Cuautitlán-
Presentación Final de Bioquímica de Sistemas.
Grupo: 1504
Presentan:
Gama Brambila Rodrigo.
Meléndez Garcia Rodrigo.
Moreno Zaragosa Ruth.
Nuñez Luna Isboset G
Uraga Ramirez Luis Manuel.
Ensayo de investigación acerca de la accion de estas moleculas esteroides apra al clase de Bioquímica de Sistemas, FES-C, Campo 1; Universidad Nacional Autonoma de Mexico.
Extracción de alcaloides de la hierba mora (Solanum nigrum L.) y caracterizac...Isbosphere
Proyecto de productos naturales , equipo #1, Grupo 1504, semestre 2010-I, Q.F.B., Facultad de Estudios Superiores Cuautitlán.
Dominguez Villa Francisco Xavier
Flores Luna Maria Fernanda
Nuñez Luna Isboset Gabriel
Manjarrez Cano Ana Karen
Vargas Neri Lucero del Carmen
Uraga Ramirez Luis Manuel
Alimentos Funcionales: Prebioticos y Probioticos.Isbosphere
Presentacion para la clase de Bioquimica de Alimentos, grupo 1552.
UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO.
Facultad de Estudios Superiores Cuautitlan Izcalli.
Bioquimica de Alimentos.
Semestre 2010-I
Realizado por:
Alvarez Almazán Samuel.
Meléndez García Rodrigo.
Nuñez Luna Isboset Gabriel.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
The Indian economy is classified into different sectors to simplify the analysis and understanding of economic activities. For Class 10, it's essential to grasp the sectors of the Indian economy, understand their characteristics, and recognize their importance. This guide will provide detailed notes on the Sectors of the Indian Economy Class 10, using specific long-tail keywords to enhance comprehension.
For more information, visit-www.vavaclasses.com
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
1. University of Western OntarioDeparment of Physiology and PharmacologyToxicology of Natural Sourced Medicine Jacob Matusinec Isboset Nuñez Luna Monica Rosas Calderón Kristine Smit (March 31th,2011)
19. History of the Memory of Water Jacques Benveniste (March 1935–October 2004) Benveniste J. Platelet-activating factor, a new mediator of anaphylaxis and immune complex deposition from rabbit and human basophiles. Nature1974; 249: 581-582. “Homeopathy is still not understood, however his efforts started a new era of rigorous scientific investigation of the field” - Alex Tournier (founding director of the Homeopathy Research Institute)
20. History of the Memory of Water Davenas E, Beauvais F, Amara J et al. HumanbasophildegranulationtriggeredbyverydiluteantiserumagainstIgE. Nature1988; 334: 287-290. “Specific information must have been transmitted during the dilution /shaking process via some molecular organization occurring in the water”
21. History of the Memory of Water “There were no methodological flaws apparent at the time.” –James Maddox, Nature Editor "There are good and particular reasons why prudent people should, for the time being, suspend judgment“ –JM Committee: James Randi: magician-cum-paranormal researcher Walter Stewart: physicist and freelance debunker at the US NIH
22. History of the Memory of Water No memory effect was observed in the blinded experiments. Although no fraudwasfound, thelack of reproducibilityledNaturetoconcludethattherewas no substantialbasisforBenveniste’sclaim.
23. History of the Memory of Water Benveniste and several collaborators worked to find the underlying mechanisms to the results on his original paper. Jacques started working with homeopath E. Attias “Digital Biology: biological interactions could be digitized”
24. History of the Memory of Water J. Benveniste; P. Jurgens, W. Hsueh and J. Aissa (February 21–26, 1997). "Transatlantic Transfer of Digitized Antigen Signal by Telephone Link". Journal of Allergy and Clinical Immunology. J. Benveniste; Aissa, J., Guillonnet. "The molecular signal is not functional in the absence of "informed water"". Medical Hypotheses54 J. Benveniste; Thomas Y, Schiff M, Belkadi L, Jurgens P, Kahhak L (2000). "Activation of human neutrophils by electronically transmitted phorbol-myristate acetate". FASEB Journal13 (1): 33–39
26. Homeopathy Research Experimental research – study efficacy of homeopathic remedies Basic research – elucidate nature of homeopathic remedies Clinical trials – studies clinical efficacy Theoretical models
27. Experimental Researchin vitro, cell systems, or in vivo Many models (both plant and animal) exist but only a few have been replicated independently (and quality often poor) Examples: Jacques Benveniste (1988) – IgEdegranulation Independent replication of more recent studies
28.
29. Results Successive peaks of degranulation from 40- 60% of the basophils over dilutions of anti-IgE that range from 102 to 10120 Less than one molecule of Ab is present when anti-IgE antiserum is diluted to 1014
30. “Strengths” HOWEVER… Observer bias Some participating laboratories withdrew because effect not consistent with results (not reported) Variability of the positive results was smaller than the statistically expected error or microscopical cell count and found no effect of higher dilutions Control: cells incubated in conditions identical to those with anti-IgE antiserum gave no significant degranulation (antihuman IgG antiserum) Blind double-coded procedures 6 different laboratories (in 4 countries)
37. Basic Researchelucidating the nature of homeopathic remedies… To understand mechanism, need to find a plausible theory and experimental backing to clarify how a highly diluted substance can affect a biological system Must explain how a biological effect can be brought about without a sufficient number of molecules of the active agent (found in homeopathetic remedies)
38. Clinical Research Many scientists Homeopathy violates natural laws and thus any effect must be a placebo effect Public & some physicians use of and belief in effectiveness of homeopathy is widespread Is the effect seen with homeopathic remedies equivalent to that seen with placebo?
39. If the hypothesis that all clinical effects of homeopathy are due to placebo is true: All properly conducted place-controlled trials on homeopathy would be comparing one placebo to another Thus, overall results should vary randomly around a zero difference between groups
40.
41. Results not compatible with placebo hypothesis However, insufficient evidence that any single type of homeopathic treatment is clearly effective in any one clinical condition
43. Efficacy/effectiveness paradox: Disputed evidence that homeopathy is different from placebo yet there is documented usefulness in general practice ~70% of all patients using homeopathy report they are considerably improved after treatment (effects remain stable during follow-up periods of 2-5 years) Before clinical homeopathy research can proceed with success, needs a viable theory…
45. Local Mechanisms Homeopathic remedies behave in a way similar to any other medicine The production process produces some kind of template, image, or imprint of the original substance, and this “information” is the active ingredient
46. Local Mechanisms Hydrogen bonds and van der Waal’s interactions Electric fields can be modified and modulated by their surrounding Laws of thermodynamics?
47. Examples of local mechanisms Remaining material on surfaces Nanobubbles Remaining particle clusters Ethanol solution complexity Natural water clusters redox molecules produced from water
48. Non-local Hypotheses “Correlations are somehow established between patient, practitioner and remedy, ultimately leading to an observed change in the patient’s state of health”. Even more controversial than local mechanisms: quantum theory applicable in our macroscopic domain??
49. Non-local Hypotheses “Quantum entanglement: property of the quantum mechanical state of a system containing two or more objects, where the objects that make up the system are linked in such a way that the quantum state of any of them cannot be adequately described without full mention of the others, even if the individual objects are spatially separated.”
52. Empirical Approaches Dr. Masaru Emoto. He claims about the «resonance» present in words and how these vibrations change in health and disease.
53. Emoto’s experimentsRice experiment Three separate treatments to beakers containing rice and water: Thank the flask or say something nice Tell nasty and rude phrases. Ignore it.
54. Emotto’sWaterCrystals (2003) 2000 people (Tokyo) prayedtowatersamplesstoredon a electromagneticshieldedroom. (CA,USA). Control sampleswere in other place. Pictures of bothsampleswereblindlytaken. Afterthat, thepictureswereshownto 100 judges. (Theydidnotknowwhichcrystalwasfrowhichsample) Statistically, judgesprefertheprayedcrystal.
57. Water memory explanation? In 2003, the physics journal: Physica published an experiment on water memory Louis Rey. Thermoluminescence: The technique involves bathing a chilled sample with radiation. When the sample is warmed up, the stored energy is released as light in a pattern that reflects the atomic structure of the sample
72. How are these clusters formed?Theodore Grotthus (1806)
73.
74. The shaking of homeopathic dilutions generate dissipative structures. “The physicochemical parameters electrical conductivity and heat of mixing are in fact functions of the number, size and shape of the dissipative structures”
75. Expert Opinions Against Homeopathy Steven Novella, Yale University, New Haven, CT. Thelaw of similars & law of Infintesimals: nobiologicalplausability. Homeopathyisstill a philosophy-based medicine Hahnemann had his theory of illness, largely based on the notion of miasms. Theorists invoking quantum mechanics?
76. Expert Opinions Against Homeopathy Donald Marcus. Baylor University, Waco, TX. Professor Ernst, Exeter University in England: based on over 20 reviews since 1997 believes there is no evidence homeopathic remedies differ from placebos ENHS conclusion: insufficient evidence to support the use of homeopathy. The Lancet: “there’s no point in making further investments in research in clinical trials in homeopathy.”
77. Expert Opinions Against Homeopathy No FDA regulations Safety concern: some homeopathic practioners recommend against vaccination. Some people who practice homeopathy are unqualified to perform general medical evaluations and may miss serious and treatable conditions. The Heisenberg principle concerns atomic and subatomic particles and it does not invalidate Newtonian physics: no justification for taking this concept from physics and applying it to health care.
78.
79. Many documented effects of homeopathy attributed to placebo and the fact that Homeopathic professionals do not acknowledge this is against ethical guidelines defined by the Society of Homeopaths
80.
81. Conclusion Jury is still out on whether or not “water memory” truly exists. More research needed, but as of today Potentiation and the other pillars of homeopathy are not supported by the scientific community.
82. Conclusion Some empirical evidence shows structural cahnge in water but biological plausibility still uncertain. Both Homeopathic practitioners and scientific community remain steadfast in their beliefs. Possible that the truth lies somewhere between these two extremes
83. Davenas E, Beauvais F, Amara J, Oberbaum M, Robinzon B, Miadonna A, Tedeschi A, Pomeranz B, Fortner P and Belon P (1988) Human basophil degranulation triggered by very dilute antiserum against IgE. Nature 333:816-818. Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, Van Rompay M and Kessler RC (1998) Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA 280:1569-1575. EliaV, Baiano S, Duro I, Napoli E, Niccoli M and Nonatelli L (2004) Permanent physico-chemical properties of extremely diluted aqueous solutions of homeopathic medicines. Homeopathy 93:144-150. EliaV, Baiano S, Duro I, Napoli E, Niccoli M and Nonatelli L (2004) Permanent physico-chemical properties of extremely diluted aqueous solutions of homeopathic medicines. Homeopathy 93:144-150. References
84. References Elia V, Napoli E and Germano R (2007) The 'Memory of Water': an almost deciphered enigma. Dissipative structures in extremely dilute aqueous solutions. Homeopathy 96:163-169. Guggisberg AG, Baumgartner SM, Tschopp CM and Heusser P (2005) Replication study concerning the effects of homeopathic dilutions of histamine on human basophil degranulation in vitro. Complement Ther Med 13:91-100. KleijnenJ, Knipschild P and ter Riet G (1991) Clinical trials of homoeopathy. BMJ 302:316-323. Maddox J, Randi J and Stewart WW (1988) "High-dilution" experiments a delusion. Nature 334:287-291. Milgrom LR (2009) The eternal closure of the biased mind? The clinical and scientific relevance of biophysics, infinitesimal dilutions, and the memory of water. J Altern Complement Med 15:1255-1257.
85. References Milgrom LR (2006) Is homeopathy possible? J R SocPromot Health 126:211-218. Milgrom LR (2006) Towards a new model of the homeopathic process based on quantum field theory. ForschKomplementmed13:174-183. Radin D, Hayssen G, Emoto M and Kizu T (2006) Double-blind test of the effects of distant intention on water crystal formation. Explore (NY) 2:408-411. Shaw D (2010) Unethical aspects of homeopathic dentistry. Br Dent J 209:493-496. Walach H, Jonas WB, Ives J, van Wijk R and Weingartner O (2005) Research on homeopathy: state of the art. J Altern Complement Med 11:813-829.
Editor's Notes
Hi im…….
Alexander Beydeman (1826—1869) Painting by ABAllopathic medicine refers to the practice of conventional medicine, and especially the practices now referred to as heroic medicine. It was coined by Samuel Hahnemann (1755–1843) in 1810. Although allopathic medicine was rejected as a term by mainstream physicians, it was adopted by physicians with unconventional training to refer pejoratively to physicians who had undergone a more traditional course of educationAllo means different, Where homeo means same, consitent. Implying and underlying idiology
costunethicalaviodingconentional medicine
Many studies showing publication bias, poor methodological practices, and almost always homeopathic reports are positive and scientific reports are negetive
Some conventional remedies do follow this pattern but rarely. Likely not more often than chance
Difficult to argue. Beliefs do play a well documented role in medicine. Many accounts that placebo effect is greater if one trusts their physician. Or if treatment is carried about by a religious healer. That’s our perspective as sceintists, but maybe placebo affect and vital force are one in the same. If so patients have the right to retain their beliefs (especially considering in this case it only improves their health)
These will be discussed later. But briefly many studies have found effects of homeopathic solutions diluted to the point of no parent molecule still having an effect on cell cultures.How? They say water memory
Basophildegranulation assessed by counting cells with metachromatical propertiesPicture:http://image.bloodline.net/stories/storyReader$1676Toluidine blue – positive: basophile (large dark granules)Negative neutrophiles (2)
Degranulation observed after exposure of leukocyte preparations to low antiserum dilutionsSuccessive peaks of degranulation varying between 40-60% were found down to 1E60 dilutionWaves of basophildegranulation were also seen with substances other than anti-serum**less than one molecule of Ab….BUT experiments reported detected significant basophildegranulation down to the 1x10120 dilution
Observer bias: Lab assistants were being subconsciously selective in the way they interpreted data
Aimed to independently replicate former studiesSlightly different methodology: reported inhibitory effect of highly diluted histamine solutions on anti-IgE induced basophildegraulation using flow-cytometryComputer generated randomization
One minor statistically significant inhibitory effect at a histamine dilution of 10-22 M, when compared to the effect of water “diluted” to 10-22 MWhen same data were compared a posteriori to other reasonable controls, statistical significance lostPossibly: statistical significance was reached only because the standard deviation of the inhibition with this dilution level happened to be small. Since the p-value is rather modest (p=0.018), the evidence for rejecting the null hypothesis (“no difference between histamine and water dilutions”) is not overwhelming, i.e., it is possible that this result is due to chance only
Discussed further by Isboset/Monica…
If the hypothesis that all clinical effects of homeopathy are due to placebo is true, all properly conducted placebo-controlled trials on homeopathy would be comparing one placebo to anotherTherefore, overall results should vary randomly around a zero difference btw groups Could falsify placebo hypothesis if all properly conducted comparisons of homeopathy and placebo showed a pooled effect significant different from zero difference, or if there is independently replicated evidence for an effect over place in at least one consistently applied homeopathic approach
Are we they hurting anyone?-unethical practices (but we get that in conventional medicine too)-costFailure to use conventional medicine.No FDA regulations or governing body to standardize homeopathic and conventional therapies to eachother.If we could remedy this it would go a long way in harmonizing the two fields as I’m sure no Physician cares how a patient is getting better as long as they get there.section 11 of the Code of Ethics and Practice) states that 'Homeopaths report research findings and clinical experience methodically, honestly and without distortion. All speculative theories will be stated as such and clearly distinguishedSafety concern: some homeopathic practioners recommend against vaccination.
As scientists we must accept that we do not know everything; if we did science would cease to exist. Yet, we are often unwiling to accept unconventional methodsSoccer player analogy
As scientists we must accept that we do not know everything; if we did science would cease to exist. Yet, we are often unwiling to accept unconventional methodsSoccer player analogy