This document summarizes the key challenges in designing user experiences for large-scale web applications. It discusses how unclear requirements, changing scopes, siloed teams with low understanding of users and ecosystems can lead to compromised experiences, stretched timelines and increased costs. It emphasizes defining user needs through user profiles, tasks and scenarios to understand what users really need rather than technical constraints. Finally, it stresses the importance of communication, knowledge management and reuse of design patterns, guidelines and components to ensure consistency and performance.