This document discusses urinalysis, including why it is performed, what is checked during urinalysis, and how urinalysis is performed. Urinalysis is used as part of routine medical exams and to diagnose conditions like urinary tract infections and diabetes. It can check for things like pH, protein, sugar, ketones, bilirubin, white blood cells, and red blood cells. Tests are performed to check for these substances, including Benedict's test for sugar, tests for albumin and bile salts, and microscopic examination of urine under a microscope.
General Urine Examination (GUE) or Urinalysisyassershsh1
General urine examination (GUE) and urinalysis are terms often used interchangeably to describe a common medical test that involves the analysis of a person's urine
Laboratory and diagnostic examination(urine analysis)anjalatchi
laboratory investigation like urine and stool test like meaning, type of test, interpretation nurses role in laboratory investigation collectin and transportation etc.
General Urine Examination (GUE) or Urinalysisyassershsh1
General urine examination (GUE) and urinalysis are terms often used interchangeably to describe a common medical test that involves the analysis of a person's urine
Laboratory and diagnostic examination(urine analysis)anjalatchi
laboratory investigation like urine and stool test like meaning, type of test, interpretation nurses role in laboratory investigation collectin and transportation etc.
Urine test strips are an easy and convenient way of home testing your urine, covering a wide range of parameters. This presentation explains all about it.
Albumin is a large molecule protein found in the blood, under normal circumstances it does not pass into the urine. If albumin occurs in the urine it could indicate infection of the urinary tract, kidney damage as in nephritis and toxemia in pregnancy. A urine for albumin test is a screening test to look for the presence of albumin in the urine .An albumin test cheeks urine for a protein called albumin for urine . Albumin is normally found in blood and filtered by kidneys. When the kidneys are working as the slow, there may be very small amount albumin in the urine .But when the kidneys are damage ,abnormal amounts of albumin leaks in the urine. This is called albuminuria.
Stool is not just a simple waste material. Some stool tests can be easily used in primary care in the differential diagnosis of disorders such as gastrointestinal infections, malabsorption syndromes,
Urine test strips are an easy and convenient way of home testing your urine, covering a wide range of parameters. This presentation explains all about it.
Albumin is a large molecule protein found in the blood, under normal circumstances it does not pass into the urine. If albumin occurs in the urine it could indicate infection of the urinary tract, kidney damage as in nephritis and toxemia in pregnancy. A urine for albumin test is a screening test to look for the presence of albumin in the urine .An albumin test cheeks urine for a protein called albumin for urine . Albumin is normally found in blood and filtered by kidneys. When the kidneys are working as the slow, there may be very small amount albumin in the urine .But when the kidneys are damage ,abnormal amounts of albumin leaks in the urine. This is called albuminuria.
Stool is not just a simple waste material. Some stool tests can be easily used in primary care in the differential diagnosis of disorders such as gastrointestinal infections, malabsorption syndromes,
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As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
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Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. Why is urinalysis performed?
1.It is a part of a routine medical examinations, especially in people who are:
1. Pregnant
2. Pre-surgery preparation
3. Hospital admission
2.It helps diagnose a particular medical conditions such as:
1. Urinary tract infection
2. Diabetes mellitus
3. Kidney-related diseases
4. Liver-related diseases (2, 3)
3.It helps in monitoring the patient’s medical condition, especially those undergoing
treatments for the conditions mentioned above. It helps assess whether the
treatment the patient currently receives is effective.
3. What is being checked in
urinalysis?
•Presence of cells
•Cellular fragments
•Byproducts of both normal and abnormal metabolisms
•Bacteria
4. Checking the composition
of urine
Visual examination/physical examination
It checks the color and clarity of urine.
Chemical examination
It checks for chemical substances that might be present in urine, which
aids in checking the person’s health condition, urine concentration, and the
existence of a particular disease.
Microscopic examination
It counts the components of urine in detail such as the type of cells present,
crystal formation, cast, bacteria, mucus, and other components.
5. A chemical analysis of urine using a urine test strip
A urine test strip using a dipstick is one of the commonly used methods of
checking the chemical components of urine. The strip has squares of different
colors attached to it. The whole strip is dipped in the urine sample and you have
to watch out for changes in colors of each square.
It would only take a few seconds to notice the changes in color. It is a must to
observe the proper time of dipping and reading the result as too early or too
long could lead to an inaccurate result.
6. What is checked during urinalysis?
1.Acidity of urine – The pH level of urine is checked to determine if you are suffering from urinary tract infection or
kidney-related conditions.
2.Urine concentration/specific gravity – it checks how concentrated the urine is. If the urine concentration is higher
than normal, then it is an indicator that you are not drinking enough fluids.
3.Protein – It is just normal to have a low protein in the urine. However, if there is a large number of protein in the
urine, it is an indicator of a kidney-related problem.
4.Sugar – if there is moderate to a huge number of sugar in the urine, it is indicative of diabetes. Hence, additional
testing will be needed to confirm the condition of the patient.
5.Ketones – Any amount of ketone in urine could be a sign of diabetes mellitus. Hence, additional testing is needed.
6.Bilirubin – it is a byproduct of the breakdown of red blood cells. Bilirubin is carried in the blood and passed into the
liver for excretion and become a part of the bile. If bilirubin is detected in urine, it might indicate a damage to the
liver/liver-related diseases.
7.Nitrites/leukocyte esterase – leukocyte esterase and nitrites are products of white blood cells and if they are
detected in urine, it could be a sign of urinary tract infection.
8.Blood – The presence of blood in urine can be very alarming. It could indicate a blood-related disorder, kidney or
bladder stone, kidney damage, infection, or cancer in the kidneys or bladder. However, it is not an indicative sign.
Additional testing should be done to confirm the diagnosis.
7. Microscopic examination of
urine
Drops of urine are examined under the microscope to check for
the following:
•White blood cells/leukocytes – It is a sign of infection
•Red blood cells/erythrocytes – It could be a sign of a possible
blood disorder, bladder cancer, or kidney-related diseases.
•Yeast/bacteria – it could suggest an underlying infection.
•Casts – It is a tube-shaped protein which could indicate an
underlying kidney disorder.
•Urinary Crystals – It could be an indicator of kidney stones.
8. Cells that can be checked in urinalysis
1.There are a number of cells that can be detected in a routine urine test.
These include red blood cells, white blood cells, and epithelial
cells.Epithelial cells – They are cell linings found in different parts of the
body, specifically in the skin, vagina, ureter, urethra, and bladder. If there’s
epithelial cells in urine, it could be associated with infection or inflammation
of the bladder or urethra.
2.Red blood cells/erythrocyte – It could indicate bleeding in the lower part
of the urinary tract, especially in the ureter, urethra, and bladder.
White blood cells/leukocytes – The presence of white blood cells in urine
could indicate a urinary tract infection. The suspicion can be confirmed if
aside from white blood cells, there are other components present like
bacteria, nitrite, and leukocyte esterase.
9. Test for sugar - benedict’s test
Benedict’s test is used as a simple test for reducing sugars. A reducing sugar is a
carbohydrate possessing either a free aldehyde or free ketone functional group as part
of its molecular structure. This includes all monosaccharides (eg. glucose, fructose,
galactose) and many disaccharides, including lactose and maltose.
Benedict’s test is most commonly used to test for the presence of glucose in urine.
Glucose found to be present in urine is an indication of Diabetes mellitus
10. Procedure
Take 5 ml (one teaspoon) of Benedict’s solution in the test-tube.
Holding the test-tube with the holder, heat it over a spirit lamp till the Benedict’s
Solution boils without overflowing.
Drop 8 to 10 drops of urine into the boiling Benedict’s solution.
After again boiling the mixture, let it cool down.
While cooling, the mixture changes color.
Observe the color change and precipitate formation and analyze the test result
12. Test For Albumin
Fill three-fourth of a test tube with filtered urine (filtering removes pus if present).
See the reaction of the urine is acidic. If found alkaline, add one drop of acetic acid and make it acidic.
Heat the upper third of the urine over sprit lamp and allow it to boil.
A cloud may appear either due to phosphate or albumin.
Add acidic acid drop by drop in to the test tube.
If the urine is still cloudy it indicates the presence of albumin.
If it becomes clear it indicates the presence of phosphates.
No albumin is presence in the normal urine.
If the urine is highly acidic or highly alkaline, the reading will be false.
13. Test For Bile Salts (Hey’s Test)
Take a test tube, half full of urine.
Sprinkle sulphur powder on the surface of the urine.
If the powder sinks down to the test tube, it indicated the presence of
bile salts.
This is because, bile salts reduce the surface tension of the urine and
allows the sulphur powder to sink down
14. Test for Bile Pigments
Fill three-fourth of a test tube with urine.
Add iodine drops along the sides of the test tube, so as to form the layer on the surface of the urine.
A green color at the junction of the two liquids indicates the presence of bile pigments.
Discard the urine and clean the test tube.