This document discusses the Ayurvedic concept of Upadhatus, which are the secondary tissues that provide support to the main tissues (Dhatus). It describes the different Upadhatus according to Charak and Sharangdhara, and explains that diseases can arise when the Upadhatus are deranged (Pradoshaj vikar) due to problems with the channels of circulation (Srotas), digestive fire (Agni), or vitiation of the doshas. Various diseases are mentioned where specific Upadhatus are involved, such as Vasa in prameha and Kandara in vishwachi.

1. Upadhatu pradoshaj vikar
Dr. Shivani Gupta Borele

2. Introduction
• Updhatus are the one which are derived from Sara Bhaga of each
Dhatu which supports the Dhatus. Knowledge of Updhatu could be
beneficial to introduce the known and lesser-known concepts related
to manifestation of various diseases. Ayurvedic concept of
Pradoshaja Vikara determines profound insight in understanding the
disease and its manifestation.
• Upadhautus word is mentioned by Acharya Kashyap in Kashyap
samhita.
• "उपमिम िं धा ुम िः इम उपधा ुिः।
• Acharya Chakrapani comments on Ch.Chi. 15/17 that updhatu
provides only base for the body while base and nutrition both are
provided by Dhatu.

3. • Acharya Charak and Acharya Sharngadhar has mentioned
- Acharya Charak
Updhatu
Acharya
Sharanghar
Upadhatu
Dhatu
Ras Stanya, Artava Stanya
Rakta Kandara, Sira Aartav
Mansa Vasa, Shatatwacha Vasa
Meda Snayu Sweda
Asthi - Danta
Majja - Kesharoma
Shukra - Oja

4. Concept of Nitya and Anitya
• Few Upadhatus are मित्य ाव and few are अमित्य ाव।
• मित्य ाव are those which are present since birth like snayu, sira,
twak. अमित्य ाव are Raja and stanya. This is stated by Hemadri
commentary.
• Srotus and Dhatvagni plays significant role in nutrition of
dhaatuz the nourishment of UP dhatu are dependent on
nutrition of dhaatues which intern taken care by Dhatvagni
• So any pathology in srotus, Agni and vata leads to origin of
Updhatu pradoshaj vikar.

5. Correlation of Upadhatu, Rogamarga and
Doshas
• Upadhatus usually takes Madhyam or Aabhyantar roga marga for
their diseases.
• Vata vitiates Kandra, Sira, Snayu, Sandhi,Twak in Madhyama
Rogamarga
• Pitta vitiates Twak in Bahya Rogamarga.
• Kapha vitiates Stanya, Vasa in Bahya Rogamarga.

6. Vikar
• Acharya Charak has mentioned
• Snayu, Sira, Kandara doshaj vikar which are sthambh, sankoch,
khalli, granthi, sfuran, supti.
• Along with these Artavakshaya manifest b/c of stanya n artva
dushti, pakshaghat, siraghrah, avabahuka b/c of sira,
Sandhigata vata, vatarakta, vishwachi, khanjata b/c of Kandara,
prameha and kushtha b/c of Vasa, kushth, pandu, visarp,
vatarakta b/c of twaka, amavata, sandhivata b/c of snayu as per
mentioned in the disease samprapti as per mentioned in the
samprapti of various diseases.

7. Disease Upadhatu
involved
Pradoshaj vikar description
Apabahuka Sira Shoshana,
Sankocha
“Sirakunchaya Tatrastho...”(S.Ni.1)
Prameha Vasa Sthaithilya Sukrashonitamvasamajja..”(C.Ni.4)
Uttanavat
arakta
Twak Sphurana Todasphuranaalunchna..”(C.Chi.29)
Pandu Twak Sthaithilya Twakmamsaantarashritam”(C/Chi.16)
jihwastam
bha
Sira Stambha Vagvahinisirasanstho Jihwam Stambhyate”
Vishwachi Kandara Supti Talapratyangulinama Tu Kandara” (S.Ni.1)

8. Disease Upadhatu involved Pradoshaj vikar description
Akshepaka Sira, Snayu, Kandara Shoshana Panipadam Cha Sashoshya Siraha
Sasnayukandaraha (C.S.Chi.28)
Pakshaghata Sira, Snayu Sankocha Shoshana Of Sira, Snayu Manifests With
Symptoms Like Chestanivrutti, Vaka Stambha,
Pada Sankocha
Granthi Sira Sankochya,
Granthi
Sirapratanam Sampedya
Sankochya
Gridrasi Kandara Sphurana Parshanipratyangulinam Tu Kandara
Yanilardita...”(S.Ni.1)
Spandate Muhu(C.Chi.28)