Given by Paul Volberding 9/4/12. Describes the Global Research Support Program, a CTSI program to define and address barriers to international research activities undertaken by UCSF researchers.
This document discusses navigating international partnerships for the UC system and provides a roadmap for compliance. It outlines the scale of international research activities at UCSF, including the large number of countries and faculty involved and associated risks. It also summarizes steps already taken, such as establishing insurance coverage and databases to facilitate collaboration. Additionally, it identifies further actions needed, like finalizing medical evacuation policies and registering UC foreign affiliate offices in countries like Tanzania and Kenya to legally support operations abroad.
Presentation from the conference Science diplomacy in action Governance for international science co-operation: the example of Health Research 11-12 February, 2013, arranged by the French and British embassies as a follow up to the OECD STIG project, see http://beyondstig.oecd.org
UCSF conducts extensive international HIV research. [1] Over 200 faculty conduct research in over 100 countries, with over $77 million in grants involving international work. [2] Coordination of this research has increased through groups like the AIDS Research Institute but more is needed. [3] Next steps include improving tracking of grants and sites, providing more support for researchers abroad, and creating a "one stop shop" to facilitate the entire research process from start to finish.
The International Centre for Local and Regional Development (ICLRD) is a cross-border, cross-disciplinary network that aims to build strategic planning capacity on the island of Ireland through research, collaboration, and training. It works to address information deficits and the policy-practice divide in spatial planning and local/regional development. The ICLRD conducts applied research, fosters collaboration among stakeholders, advises policymakers, and provides executive training programs nationally and internationally. It has helped facilitate cooperation agreements between councils north and south, and its current CroSPlaN II project focuses on increasing cross-border cooperation through shared services, training, and evidence-based planning.
'Investigar, educar, dialogar. Las lecciones que aprendimos de José Mariano Gago (1948-2015)'. Con este título celebramos los días 1 y 2 de junio de 2016 en la Fundación Ramón Areces un simposio para homenajear la trayectoria de quien fue ministro de Ciencia y Tecnología (1995-2002) y ministro de Ciencia, Tecnología y Educación Superior (2005-2011) de Portugal. Gago desempeñó una labor crucial en el diseño de los planes de desarrollo de la ciencia, la tecnología y la innovación, no solo en su país sino en toda Europa.
1) Dr. Patrick Corley gave a presentation on Fighting Blindness' research strategy and vision for the future at their Annual General Meeting.
2) Fighting Blindness funds research grants at several Irish universities and institutions aimed at preventing or curing blindness. Their strategic goals include advancing gene therapy, stem cell technology, and retinal implant research.
3) One of their key initiatives is establishing a Vision Research Institute to unite their research portfolio, accelerate patient-focused research, and raise the profile of vision research in Ireland. The Institute would employ dedicated researchers and help attract additional funding.
David Rampersad Presentation - Caribbean growth forum, kingston, june 18-19,2012cgrowth
Dr. David Rampersad gave a presentation on tapping into the human capital and ideas of Caribbean tertiary education institutions. He argued that higher education plays a key role in stimulating innovation by linking research, knowledge transfer, and application. However, the Caribbean currently lacks effective funding mechanisms and national innovation systems to support research. Dr. Rampersad proposed establishing a Caribbean Research and Funding Agency to provide dedicated funding for research, knowledge generation, and innovation in the region. This, along with other measures like improving technology transfer and establishing regional innovation systems, could help maximize the impact of research from Caribbean higher education institutions.
This document discusses navigating international partnerships for the UC system and provides a roadmap for compliance. It outlines the scale of international research activities at UCSF, including the large number of countries and faculty involved and associated risks. It also summarizes steps already taken, such as establishing insurance coverage and databases to facilitate collaboration. Additionally, it identifies further actions needed, like finalizing medical evacuation policies and registering UC foreign affiliate offices in countries like Tanzania and Kenya to legally support operations abroad.
Presentation from the conference Science diplomacy in action Governance for international science co-operation: the example of Health Research 11-12 February, 2013, arranged by the French and British embassies as a follow up to the OECD STIG project, see http://beyondstig.oecd.org
UCSF conducts extensive international HIV research. [1] Over 200 faculty conduct research in over 100 countries, with over $77 million in grants involving international work. [2] Coordination of this research has increased through groups like the AIDS Research Institute but more is needed. [3] Next steps include improving tracking of grants and sites, providing more support for researchers abroad, and creating a "one stop shop" to facilitate the entire research process from start to finish.
The International Centre for Local and Regional Development (ICLRD) is a cross-border, cross-disciplinary network that aims to build strategic planning capacity on the island of Ireland through research, collaboration, and training. It works to address information deficits and the policy-practice divide in spatial planning and local/regional development. The ICLRD conducts applied research, fosters collaboration among stakeholders, advises policymakers, and provides executive training programs nationally and internationally. It has helped facilitate cooperation agreements between councils north and south, and its current CroSPlaN II project focuses on increasing cross-border cooperation through shared services, training, and evidence-based planning.
'Investigar, educar, dialogar. Las lecciones que aprendimos de José Mariano Gago (1948-2015)'. Con este título celebramos los días 1 y 2 de junio de 2016 en la Fundación Ramón Areces un simposio para homenajear la trayectoria de quien fue ministro de Ciencia y Tecnología (1995-2002) y ministro de Ciencia, Tecnología y Educación Superior (2005-2011) de Portugal. Gago desempeñó una labor crucial en el diseño de los planes de desarrollo de la ciencia, la tecnología y la innovación, no solo en su país sino en toda Europa.
1) Dr. Patrick Corley gave a presentation on Fighting Blindness' research strategy and vision for the future at their Annual General Meeting.
2) Fighting Blindness funds research grants at several Irish universities and institutions aimed at preventing or curing blindness. Their strategic goals include advancing gene therapy, stem cell technology, and retinal implant research.
3) One of their key initiatives is establishing a Vision Research Institute to unite their research portfolio, accelerate patient-focused research, and raise the profile of vision research in Ireland. The Institute would employ dedicated researchers and help attract additional funding.
David Rampersad Presentation - Caribbean growth forum, kingston, june 18-19,2012cgrowth
Dr. David Rampersad gave a presentation on tapping into the human capital and ideas of Caribbean tertiary education institutions. He argued that higher education plays a key role in stimulating innovation by linking research, knowledge transfer, and application. However, the Caribbean currently lacks effective funding mechanisms and national innovation systems to support research. Dr. Rampersad proposed establishing a Caribbean Research and Funding Agency to provide dedicated funding for research, knowledge generation, and innovation in the region. This, along with other measures like improving technology transfer and establishing regional innovation systems, could help maximize the impact of research from Caribbean higher education institutions.
UCSF International Research and the Connection to the HIV CommunityCTSI at UCSF
UCSF conducts extensive international HIV research. [1] Over 200 faculty conduct research in over 100 countries, with over $77 million in awards. [2] Coordination efforts include the AIDS Research Institute and Center for AIDS Research. [3] More coordination is needed across departments and standardization of practices. [4] Early antiretroviral therapy reduces HIV transmission and provides individual health benefits, though challenges remain in implementation.
As the UNICEF Office of Research-Innocenti, we conduct research to inform policymaking and implementation. This project brief summarizes our work on research governance
Funding opportunities for researchers- Dr. Sara Banu Akkaş & Dr. Asuman Özgür...MarikaKowalska1
The presentation is about Funding Opportunities for Researchers. It was conducted by Dr. Sara Banu Akkaş & Dr. Asuman Özgür Keysan from Middle East Technical University in Turkey.
“Research Beyond Academia” - will look at how to
engage with industry as part of the research process, with
a focus on how to identify research questions that are
relevant and interesting to non-academic institutions, how
to determine appropriate potential non-academic partners
for grant proposals, and how to approach them and "sell"
your new research ideas.
Agriculture Science Agenda for Africa - Drawing on and Learning from other Ex...riatenorio
Information sharing on the development of a Science Agenda for Agriculture in Africa With inputs for CAADP-CGIAR alignment
April 13, 2013
Dublin, Ireland
The ESRC aims to engage internationally by enabling collaboration across borders, encouraging UK researchers to pursue international opportunities, and embedding international perspectives in its research priorities and activities. Its strategy includes partnership building, responsive support initiatives, strategic programs, and ensuring international engagement in training, resources, and the roles of its committees. The ESRC agenda also focuses on developments like Horizon 2020, the European Research Area, and strengthening partnerships globally.
This document discusses the evolving role of institutional repositories (IRs) in light of increasing open access mandates from research funders. It provides a brief history of IRs and outlines challenges they currently face in supporting new compliance requirements. Specifically, IRs were not designed to track publications, link them to funded projects, or manage related metadata and processes. While some institutions have separate systems like a CRIS that can fulfill more of these functions, many rely solely on their IR. The document explores potential solutions on the horizon, like the JISC Monitor project and IRUS usage statistics service, that could help institutions manage open access activities and reporting. Overall, mandates are pushing IRs in new directions beyond their original open access goals
The State of the World Bank Knowledge ServicesSDGsPlus
The document discusses the evolving focus on knowledge at the World Bank over time. It notes that in the 1990s, the Bank began articulating its role as a "Knowledge Bank" and publishing reports on how development knowledge can improve living standards. Since then, the Bank has increasingly incorporated knowledge products into its work and launched open data initiatives. The Bank's vision is to be a better facilitator of development knowledge by connecting, customizing, and producing knowledge. It is working to strengthen knowledge management, use open knowledge approaches, and launch knowledge platforms on issues like urbanization and jobs.
The document presents the Project Roadmap 2012-2016 of the Human Variome Project International Ltd. It summarizes achievements since the previous 2010 roadmap and outlines the vision, goals and plan to advance the project over the 2012-2016 period. The roadmap is built around 4 pillars - setting normative function, behaving ethically, sharing knowledge, and building capacity. Key targets include developing standards and guidelines, increasing membership, ethical and educational initiatives, and establishing more country nodes and disease-specific databases. Challenges and securing long-term funding are also discussed. Members are invited to engage in discussions and help implement the roadmap through considered actions. Progress will be reviewed at the halfway point in 2014.
A. Sallans. "Practical Applications of e-Science." Presented at the 2011 eScience Bootcamp at the University of Virginia's Claude Moore Health Sciences Library. 4 March 2011
An evaluation of the Route to Success resources, related tools and frameworks covering disease specific areas: heart failure; advanced kidney disease; dementia; and long term neurological conditions
13 December 2012 - Institute of Healthcare Management / National End of Life Care Programme
This project set out to review how the series of publications and supporting tools, resource guides and frameworks developed and supported by the National End of Life Care Programme (NEoLCP) have been utilised across four disease specific pathways.
The disease specific pathways to be included in the review are:
Heart Failure
Advanced Kidney Disease
Dementia
Long term neurological conditions
Publication by the National End of Life Programme which became part of NHS Improving Quality in May 2013
The document summarizes the AHRC International Strategy and funding opportunities. It discusses partnerships in Europe through programs like HERA and JPI. Worldwide partnerships include bilateral agreements and co-funded programs. The International Partnership Scheme provides placements for early career researchers at prestigious institutions in the US and Asia. Eligible applicants can receive funding for international research trips between 3-6 months. The document advises applicants to clearly identify relevant resources and expertise at host institutions and explain how visits will enhance their projects.
A practical experience of gender mainstreaming in research funding: small but...SUPERA project
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More infos are available here: https://www.superaproject.eu/experience-exchange-between-research-funding-organisations/
ROER4D Update March 2016 - Presentation to the Hewlett FoundationROER4D
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Research processes (partial) - Project BPM in higher education institutionsTomislav Rozman
What is HEI-UP?
HEI-UP (Improving Business Processes in Higher Education Institutions) is a European project focused on upgrading BPM in HE (higher education) institutions through a common managerial model and offering an e-learning course for HEI managers under the umbrella of the European Certification and Qualification Association (ECQA).
Why business processes?
Business process management (BPM) has been argued to be a more effective and efficient way of managing organizations than a traditional hierarchical management approach.
Today, the most successful universities are business-oriented. An efficient BPM builds up an ideal environment for achieving a high level of pedagogical, research and administrative staff, and above all, student satisfaction.
What's in there for you and your institution?
The HEI-UP project gives you the opportunity to:
● Learn from and contribute to the managerial model developed within the project
● Become more aware of internal managerial efficiency through the tools and support provided
● Successfully align your business processes with the demands and needs of your students and faculty and
● Have free access to the BPM framework developed in the HEI-UP project.
What is expected from you?
We believe in the potentials and creative spirit of professional communities, so we expect that you:
● Engage in conversation with academics and BPM practitioners by sharing
good practices and challenges you or your institution have in relation to BPM,
● Share your BPM related research findings and thus contribute to BPM research or just exchange research ideas with fellow researchers or simply
● Observe and try to get out something good for your institution.
Presentation during the 14th Association of African Universities (AAU) Conference and African Open Science Platform (AOSP)/Research Data Alliance (RDA) Workshop in Accra, Ghana, 7-8 June 2017.
Presented by Chris Higgins at the Co-Design Workshop, Machynlleth, 16 October 2014. Half-way through a 4-year project to enable "citizen scientists" to use smartphones to upload crucial scientific data, this presentation shows the current state of progress on the COBWEB project.
The University of California San Francisco East Africa Office will host its 6th biannual scientific symposium in Kampala, Uganda on July 11-12, 2014 focused on translational science. Keynote speakers will discuss topics related to malaria, HIV, cancer, and pharmacokinetics. The symposium seeks oral presentation and research proposal abstracts on translational science projects addressing malaria, HIV, HIV comorbidities, and HIV pharmacokinetics. Abstracts are due by May 12, 2014, with prizes awarded for best presentation and proposal.
This document provides instructions for filling out an emergency card for international travel. It includes sections for emergency contact numbers in the destination country, travel insurance information, contacts at the destination institution and UCSF, personal medical information, and additional emergency contacts aware of the travel. The example card shows how to fill out each section with relevant details.
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As the UNICEF Office of Research-Innocenti, we conduct research to inform policymaking and implementation. This project brief summarizes our work on research governance
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“Research Beyond Academia” - will look at how to
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relevant and interesting to non-academic institutions, how
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This document discusses the evolving role of institutional repositories (IRs) in light of increasing open access mandates from research funders. It provides a brief history of IRs and outlines challenges they currently face in supporting new compliance requirements. Specifically, IRs were not designed to track publications, link them to funded projects, or manage related metadata and processes. While some institutions have separate systems like a CRIS that can fulfill more of these functions, many rely solely on their IR. The document explores potential solutions on the horizon, like the JISC Monitor project and IRUS usage statistics service, that could help institutions manage open access activities and reporting. Overall, mandates are pushing IRs in new directions beyond their original open access goals
The State of the World Bank Knowledge ServicesSDGsPlus
The document discusses the evolving focus on knowledge at the World Bank over time. It notes that in the 1990s, the Bank began articulating its role as a "Knowledge Bank" and publishing reports on how development knowledge can improve living standards. Since then, the Bank has increasingly incorporated knowledge products into its work and launched open data initiatives. The Bank's vision is to be a better facilitator of development knowledge by connecting, customizing, and producing knowledge. It is working to strengthen knowledge management, use open knowledge approaches, and launch knowledge platforms on issues like urbanization and jobs.
The document presents the Project Roadmap 2012-2016 of the Human Variome Project International Ltd. It summarizes achievements since the previous 2010 roadmap and outlines the vision, goals and plan to advance the project over the 2012-2016 period. The roadmap is built around 4 pillars - setting normative function, behaving ethically, sharing knowledge, and building capacity. Key targets include developing standards and guidelines, increasing membership, ethical and educational initiatives, and establishing more country nodes and disease-specific databases. Challenges and securing long-term funding are also discussed. Members are invited to engage in discussions and help implement the roadmap through considered actions. Progress will be reviewed at the halfway point in 2014.
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An evaluation of the Route to Success resources, related tools and frameworks covering disease specific areas: heart failure; advanced kidney disease; dementia; and long term neurological conditions
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This project set out to review how the series of publications and supporting tools, resource guides and frameworks developed and supported by the National End of Life Care Programme (NEoLCP) have been utilised across four disease specific pathways.
The disease specific pathways to be included in the review are:
Heart Failure
Advanced Kidney Disease
Dementia
Long term neurological conditions
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What's in there for you and your institution?
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● Become more aware of internal managerial efficiency through the tools and support provided
● Successfully align your business processes with the demands and needs of your students and faculty and
● Have free access to the BPM framework developed in the HEI-UP project.
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Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
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2. Agenda
I. Scale of the Issues:
i. Size and scope of international research
ii. Potential for adverse outcomes
iii. Inefficiencies
II. What have we done
III. What more needs to be done?
IV. Key takeaways and next steps
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5. What have we done?
GlobalResearch Forum: Launched April 2012
An online moderated forum for global health research interest groups.
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6. What have we done?
The UCSF International Projects Database:
Provides access to public information; facilitating collaboration, communication, expertise, and development of
new proposals.
Current awards of UCSF global researchers through July 2012
Data feeds to Profiles, plans for automation of data capture with new central systems rollout in FY7
Example of search result:
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7. What have we done?
Global Research Consulting: Launched July 2011. One hour of free consultation.
Predominantly enquiries regarding international grants administration and policy.
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9. What more needs to be done?
• Review and provide feedback on UCOP draft policy on International Activities
UCSF has initiated registration of UC foreign affiliate offices in two PEPFAR countries and is now
registered in Tanzania as “Global Programs.” Legal registration in country allows researchers to:
– Open a local bank account
– Lease space
– Hire local staff
– Apply for work visas for UCSF staff working locally
Please review the enclosed:
– Context sheet
– UCOP Draft policy on International Activities
– Summary of comments to the UCOP policy
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10. What more needs to be done?
• Continue to identify relevant policies governing global health research and
educational activities reviewing policies and policy gaps to facilitate work
in medium and lower income countries including:
» Finalizing policy on post-exposure prophylaxis for UCSF employees (and foreign staff
members working on UCSF projects?)
» Develop policies and procedures for UC foreign affiliate operations
» Define banking/financial policies and guidelines for registered entities
» Define policies re: shipping specimens to US vs. research performed in-country
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11. What more needs to be done?
• Monitor OE pre-ward teams with extensive global research experience to
evaluate efficiency, effectiveness compared to similar grants by other teams.
• Provide more effective training of research personnel here and abroad in
support of active research projects
• Improve tracking of grants, multiple PI’s and specific sites (city, hospital, etc.,
not just country)
• Better integrate research and educational activities given similar policy
applications
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12. What more needs to be done?
• Provide a One Stop Shop for UCSF International Activities from pre-award
to project close out – including project management
(we need to define this as broadly as possible):
An expert here helping to facilitate the work over there, including developing
a foreign affiliate office to help with project management in country,
compliance (both ethical and fiscal), capacity building (for research,
education, and research administration and management), support for
educational placement and supervision of UCSF students, residents,
trainees
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13. What more needs to be done?
The Global Resource HUB will use the existing content from the GHRS web portal. Currently includes
resources for researchers, program staff working in international settings, and international visiting
scholars. The site facilitates researchers finding globally specific information. Current list of working
issues is used as a tool for continual updates and elimination of barriers for the global researcher.
The future Global Resource HUB
GHRS web portal: Working issues
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