Trypsin (EC 3.4.21.4) is a pancreatic serine protease from the S1 family and PA clan superfamily. Trypsin is a proteolytic enzyme that located in the digestive system, which is important for the digestion of proteins. In humans, trypsin is produced initially in its inactive form, trypsinogen, within the pancreas. Then, trypsinogen enters the small intestine and converted to active trypsin. The main function of trypsin is cleaving peptide chains at the carboxyl side of the amino acids lysine or arginine, except when either is followed by proline. The two main forms of trypsin are α-trypsin and β-trypsin. https://www.creative-enzymes.com/similar/Trypsin_694.html

1. Creative Enzymes
Enzymes Treatment and Pancreatic Cancer

2. Although the pancreas is small, it has an
extraordinary effect and can be said to be
one of the most important organs for
mankind. It is important because it is a
gland with internal and external secretory
functions, and its physiological and
pathological changes are closely related
to life.
The exocrine part accounts for 95% of the
pancreas and forms an exocrine gland.
Endocrine cells are called islets,
accounting for the remaining 5%, and
they spread throughout the pancreas to
form endocrine glands. The main
function of the gland is to secrete
pancreatic juice, which contains alkaline
bicarbonate and various digestive
enzymes such as pancreatic amylase,
trypsin and pancreatic lipase. Its function
is to neutralize stomach acid and digest
the sugar we consume, and nutrients such
as protein and fat.
Endocrinology can secrete a variety of
hormones, called insulin, glucagon, and
the rest are growth hormone release
inhibitors, intestinal vasoactive peptides,
gastrin and so on. These hormones do not
enter the intestine but are released into
the bloodstream. In addition to the
digestion and absorption of participating
substances, they are also responsible for
regulating whole body physiology. If
they develop a disease and the substance
is too much or insufficient, the
corresponding situation will occur.
Pancreatic cancer is the king of cancer,
and its low survival rate has not changed
significantly over the past 40 years. In
Europe, pancreatic cancer is the fourth
leading cause of cancer death, and
research predicts it will be the leading
cause of the second-largest cancer death
in the next decade. In the United States,
where medical conditions are advanced,
the annual average incidence of
pancreatic cancer is 12.5 / 100,000,
accounting for 3% of all cancers, with an
average annual mortality rate of 10.9 /
100,000.
Pancreatic cancer is considered to be the
most deadly cancer and difficult to cope
with. In order to solve the rapid formation
of tumors in vivo, experts and scientists
are busy looking for ways to stop the
development of cancer and gradually
eliminate its formation. In addition, they
are busy researching alternative therapies
for cancer patients, and one of these
alternatives to cancer is the use of
enzymes. Enzymes are thought to fight
the growth and development of
pancreatic cancer, which is well known
for its resistance to conventional
anticancer drugs.
What Are Enzymes?
Fundamental biochemical elements that
take on a vital role in the majority of
capabilities in every organ system within
the body are known as enzymes.
Enzymes are catalysts in a way. They are
components that improve the overall
pace and strengthen biochemical
reactions that handle the basic progress of
lifecycles in each productive organism.
The entire body cannot do without the aid
of enzymes because every enzyme active
in our body has an individual purpose to
fulfill.
Our gastrointestinal tract has digestive
enzymes that break down food regularly.
This program allows nutrient

3. requirements to be absorbed by the blood.
Digestive enzymes located in intestinal
fluid, pancreatic juice and gastric juice
are called proteases or proteolytic
enzymes. These proteases help to digest
proteins. In addition, proteases have been
found to have analgesic, anti-
inflammatory and analgesic effects on
immunomodulatory properties.
Enzyme treatment
Traditional medicine has long benefited
from the advantages of enzymes. Even
today, plant extracts with a specific
number of proteolytic enzymes are
widely used in medicine to treat various
diseases. In addition to proteolytic
enzymes in plants such as bromelain and
papain, proteolytic pancreatic enzymes
such as chymotrypsin and pepsin are also
very valuable in enzymatic therapy.
Ongoing research shows that in cancer
treatment, proteases or proteolytic
enzymes can deliver superior benefits by
expanding the lives of sick patients. It
reduces the symptoms of the disease as
well as the adverse side effects caused by
basic cancer therapies such as
chemotherapy and radiation therapy.
Basic enzyme therapy is a routine
procedure that is divided into four parts.
It is recommended that patients who
choose other treatments for pancreatic
cancer (eg, enzyme therapy) take large
amounts of enzymes and also require
them to control the organic diet without
any processed food. In addition, they are
required to take large amounts of
minerals and vitamin supplements. Every
day, detoxification methods such as
coffee enema are used to continuously
flush out the waste generated in the liver.
Alternative treatments for pancreatic
cancer have been carefully reviewed and
evaluated and used as an alternative to
basic cancer treatment. Treatments like
chemotherapy can have a negative
impact on cancer patients, so scientists
are beginning to focus on more plant-
based “moderate” alternative therapies.