Explore creative enzymes's enzyme products for triglyceride kit
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A Triglyceride Kit is used to measure triglyceride concentration in mammalian samples. The triglyceride assay is easy and sensitive. Triglycerides are converted to free fay acids and glycerol. Glycerol is then oxidized to generate a product that reacts with a probe to generate colour and fluorescence. Creative Enzymes provides enzymes that are essential to produce triglyceride kits. https://diagnostic-enzymes.creative-enzymes.com/glycerol-3-phosphate-oxidase-from-pediococcus-sp-item-10.html
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High level products & services from creative peptides for your research career
High level products & services from creative peptides for your research career
Enzymes in Blood Lipid Metabolism.pdf
Blood lipids refer to a group of fatty substances present in blood, mainly including cholesterol and triglycerides. There are generally two forms of cholesterols circulating in the bloodstream: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Abnormal lipid level in blood is always associated with a number of diseases, such as high blood pressure, coronary arteries, hypothyroidism, type 2 diabetes, obesity, pancreatitis, et al. https://diagnostic-enzymes.creative-enzymes.com/blood-lipids.html
Native Bacillus licheniformis Protease at Creative Enzymes
A protease is an enzyme that helps proteolysis: protein catabolism by hydrolysis of peptide bonds. The native Bacillus licheniformis protease belongs to the serine endopeptidase subtilisin family, which breaks the peptide bond non-specifically under alkaline conditions. The enzyme is active in aqueous solutions and in some organic solvents such as dry octane. The protease is inactivated by serine active-site inhibitors, such as phenylmethylsulfonyl fluoride (PMSF) and diisopropyl fluorophosphate. https://www.creative-enzymes.com/product/native-bacillus-licheniformis-protease_936.html
Molecular biology grade lyophilized powder of Recombinant Proteinase K
Proteinase K is a broad-spectrum serine protease originally isolated from the fungus Engyodontiumalbum (Tritirachium album). The enzyme was named "proteinase K" for its ability to digest keratin. Structural and molecular biology studies suggest that the enzyme belongs to the subtilisin family characterized by a catalytic triad (Asp39-His9-Ser2) in the active site. Proteinase K has no pronounced cleavage specificity and the preferential cleavage site is the peptide bond adjacent to hydrophobic amino acids. https://www.creative-enzymes.com/product/proteinase-k-from-tritirachium-album-limber-recombinant_3427.html
Food Grade B-Amylase
β-Amylase hydrolyzes the a-(1,4)glucan linkages in polysaccharides of three or more a-(1,4)linked D-glucose units. Natural substrates such as starch and glycogen are broken down intoglucose and maltose. β-amylase, also known as starch β-1,4-galactosidase, is an exo-amylase that cleaves the separated a-1,4 bonds from non-reducing ends when acting on starch and produces maltose. Because amylase changes the configuration of C1 in the hydrolysate maltose molecule from alpha type to beta type during the hydrolysis process, it is named β-amylase. https://www.creative-enzymes.com/product/-amylase-food-grade-_3167.html
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High level products & services from creative peptides for your research career
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Enzymes in Blood Lipid Metabolism.pdf
Blood lipids refer to a group of fatty substances present in blood, mainly including cholesterol and triglycerides. There are generally two forms of cholesterols circulating in the bloodstream: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Abnormal lipid level in blood is always associated with a number of diseases, such as high blood pressure, coronary arteries, hypothyroidism, type 2 diabetes, obesity, pancreatitis, et al. https://diagnostic-enzymes.creative-enzymes.com/blood-lipids.html
Native Bacillus licheniformis Protease at Creative Enzymes
A protease is an enzyme that helps proteolysis: protein catabolism by hydrolysis of peptide bonds. The native Bacillus licheniformis protease belongs to the serine endopeptidase subtilisin family, which breaks the peptide bond non-specifically under alkaline conditions. The enzyme is active in aqueous solutions and in some organic solvents such as dry octane. The protease is inactivated by serine active-site inhibitors, such as phenylmethylsulfonyl fluoride (PMSF) and diisopropyl fluorophosphate. https://www.creative-enzymes.com/product/native-bacillus-licheniformis-protease_936.html
Molecular biology grade lyophilized powder of Recombinant Proteinase K
Proteinase K is a broad-spectrum serine protease originally isolated from the fungus Engyodontiumalbum (Tritirachium album). The enzyme was named "proteinase K" for its ability to digest keratin. Structural and molecular biology studies suggest that the enzyme belongs to the subtilisin family characterized by a catalytic triad (Asp39-His9-Ser2) in the active site. Proteinase K has no pronounced cleavage specificity and the preferential cleavage site is the peptide bond adjacent to hydrophobic amino acids. https://www.creative-enzymes.com/product/proteinase-k-from-tritirachium-album-limber-recombinant_3427.html
Food Grade B-Amylase
β-Amylase hydrolyzes the a-(1,4)glucan linkages in polysaccharides of three or more a-(1,4)linked D-glucose units. Natural substrates such as starch and glycogen are broken down intoglucose and maltose. β-amylase, also known as starch β-1,4-galactosidase, is an exo-amylase that cleaves the separated a-1,4 bonds from non-reducing ends when acting on starch and produces maltose. Because amylase changes the configuration of C1 in the hydrolysate maltose molecule from alpha type to beta type during the hydrolysis process, it is named β-amylase. https://www.creative-enzymes.com/product/-amylase-food-grade-_3167.html
Native Bacillus licheniformis Protease
A protease is an enzyme that helps proteolysis: protein catabolism by hydrolysis of peptide bonds. The nave Bacillus licheniformis protease belongs to the serine endopeptidase subtilisin family, which breaks the peptide bond non-specifically under alkaline conditions. The enzyme is active in aqueous solutions and in some organic solvents such as dry octane. The protease is inactivated by serine active-site inhibitors, such as phenylmethylsulfonyl fluoride (PMSF) and diisopropylfluorophosphate. https://www.creative-enzymes.com/product/native-bacillus-licheniformis-protease_936.html
Proteinase K
Proteinase K is a stable and highly reactive serine protease. Evidence from crystal and molecular structure studies indicates the enzyme belongs to the subtilisin family with an active-site catalytic triad (Asp39-His69-Ser224). It is stable in a broad range of environments:pH, buffer salts, detergents (SDS), and temperature. In the presence of 0.1-0.5% SDS, proteinase K retains activity and will digest a variety of proteins and nucleases in DNA preparations without compromising the integrity of the isolated DNA. https://www.creative-enzymes.com/product/proteinase-k-from-tritirachium-album-limber-recombinant_3427.html
What Are Probiotics?
Probiotics are living microorganisms that co-exist with humans. Different from pathogenic microorganisms, probiotics are beneficial, and sometimes essential to health. For example, intake of probiotics can increase the number of beneficial bacteria in the intense, maintain the dynamic balance of intestinal flora, and enhance
gastrointestinal health. https://www.creative-enzymes.com/cate/probiotics_99.html
Tn5 Transposase
Tn5 Transposase is a hyperactive form of Tn5 transposase. This enzyme can be used to randomly insert Tn5 transposon into target DNA. Robust Tn5 Transposase recognizes inside end sequences, outside end sequences and mosaic end sequences of Tn5 transposon. https://www.creative-enzymes.com/product/tn5-transposase_8479.html
Enzymes in blood lipid metabolism
Blood lipids refer to a group of fatty substances present in the blood, mainly including cholesterol and triglycerides. There are generally two forms of cholesterols circulating in the bloodstream: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Abnormal lipid level in blood is always associated with a number of diseases, such as high blood pressure, coronary arteries, hypothyroidism, type 2 diabetes, obesity, pancreatitis, et al. https://diagnostic-enzymes.creative-enzymes.com/blood-lipids.html
Creative Enzymes's Diagnostic Enzymes for POC Biosensor
Point-of-care testing (POCT) refers to a group of immediate test approaches that are implemented near or at the site of patient care. Various portable and handheld instruments and test kits, or biosensors, have supplemented the POC. Creative Enzymes serves diagnostic enzyme products to optimize your POC biosensors. https://diagnostic-enzymes.creative-enzymes.com/poct-bio-sensor.html
Explore Enzymes Involved in Blood Lipid Metabolism at Creative Enzymes
Blood lipids refer to a group of fay substances present in blood, mainly including cholesterol and triglycerides. There are generally two forms of cholesterols circulating in bloodstream: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Abnormal lipid level in blood is always associated with a number of diseases, such as high blood pressure, coronary arteries, hypothyroidism, type 2 diabetes, obesity, pancreas, et al. https://diagnostic-enzymes.creative-enzymes.com/blood-lipids.html
Creative Enzymes: Antiallergic Probiotic Formula
Probiotics may exhibit antiallergic effects by degradation or structural modification of enteral antigens, stabilization of aberrant microbiota, improvement of the gut-barrier function, secretion regulation of pro-inflammatory mediators, and development of the immune system. https://probiotic.creative-enzymes.com/multi-strain-probiotics/antiallergic-formula.html
Enzyme immobilization
As an enzyme expert, Creative Enzymes is engaged in providing the best products and services for worldwide researchers, especially for enzymes modification. Immobilization is one of the most popular methods that were initially developed for biotechnology processes. Creative Enzymes offers enzyme immobilization services with reliable outcomes, improved performance, and surface analysis. https://www.creative-enzymes.com/service/Enzyme-Modification-By-Immobilization_366.html
Featured enzyme products for diagnostic use
Creative Enzymes is a worldwide leading company in diagnostic enzymes manufacturing and supply. We are committed to providing our customers with diverse enzyme products and custom enzyme-related services for medical and research diagnosis. Relying on our professional team and state-of-art technologies, we have gained solid reputation for having top of the line products and services.
Probiotics Powder
Creative Enzymes is a professional and experienced supplier of probiotics. In the past decade, Creative Enzymes mainly provides enzyme-related products and services. With the continuous expansion of business areas and scale, we have set foot in other areas and established a sound probiotic production and supply chain. Based on our high-quality products and services, as well as the unique advantages of large-scale production, our probiotic products are widely favored by industrial customers and scientific research customers.
Enzymes for Research and Diagnostic Use
Creative Enzymes is a world-wide provider of the best enzyme products. We now offer medical enzymes for pharmaceutical and diagnostic uses. In contrast to the industrial uses, enzymes of therapeutic uses are requested in relatively lower amounts but at a very high degree of purity and specificity. We have the capability to assure high-quality enzyme products based on our advanced equipment and professional techniques. In the past few years, the reliability of our products has been approved by thousands of customers and scientists. Specialized in the medical industry, the various kinds of enzyme products of Creative Enzymes will support your research in multiple areas.
Enzyme immobilization
As an enzyme expert, Creative Enzymes is engaged in providing the best products and services for worldwide researchers, especially for enzymes modification. Immobilization is one of the most popular methods that were initially developed for biotechnology processes. Creative Enzymes offers enzyme immobilization services with reliable outcomes, improved performance, and surface analysis.
Diagnostic enzymes
Creative Enzymes is a worldwide leading company in diagnostic enzymes manufacturing and supply. We are committed to providing our customers with diverse enzyme products and custom enzyme-related services for medical and research diagnosis. Relying on our professional team and state-of-art technologies, we have gained solid reputation for having top of the line products and services. https://diagnostic-enzymes.creative-enzymes.com/
Biocatalysis services at Creative Enzymes
Creative Enzymes has long demonstrated expertise and reliability in development and establishment of biocatalysis systems. We provide products, services, and consultation covering every step in the whole process of a biocatalyst development, including the design, modification, expression, purification, production, and validation of specific enzymatic or microbial systems that catalyze the desired reactions. https://www.creative-enzymes.com/service/Biocatalysis-Services_67.html
Introduction to Collagen and collagenase
Triplehelical domain of chicken sternum collagen type II. Gnd-HCl extracon, pepsin digeson, salt precipitaon, ion exchange chromatography, gel-filtraon. Nave type II collagen has posive effects on the treatment of early rheumatoid arthris. https://www.creative-enzymes.com/product/native-chicken-collagen-type-ii_3352.html
Featured Enzyme Products for Diagnosc Research
The abnormality in enzyme metabolism system leads to many metabolic diseases that are related to components of enzyme metabolism system. Enzymes have been widely used in clinical examinaon as the preferred markers in various disease states such as myocardial infarcon, jaundice, pancreas, cancer, neurodegenerave disorders, etc. They provide insight through the ability of diagnosis, prognosis, and assessment of response therapy. https://www.creative-enzymes.com/promotions/Featured-Enzyme-Products-For-Diagnostic-Use_6.html
Collagen and collagenase at Creative Enzymes
Triplehelical domain of chicken sternum collagen type II. Gnd-HCl extracon, pepsin digeson, salt precipitaon, ion exchange chromatography, gel-filtraon. Nave type II collagen has posive effects on the treatment of early rheumatoid arthris.
Collagen and collagenase
Triplehelical domain of chicken sternum collagen type II. Gnd-HCl extracon, pepsin digeson, salt precipitaon, ion exchange chromatography, gel-filtraon. Nave type II collagen has posive effects on the treatment of early rheumatoid arthris.
Enzymes in food industry
Enzymes are known to aid food processing in a wide variety of applications, for example manufacturing of cheese, vinegar and wine; leavening of bread; brewing of beer and so on. In these processes enzymes help to save energy and resources, as well as improve the overall efficiency. In many instances, the use of enzymes has been proved to decrease the volumes and toxicity of byproducts and effluents. Creative Enzymes provides a wide range of products including high purity enzymes and custom blends, which can be readily used in food and beverage processes. https://www.creative-enzymes.com/cate/Food-And-Beverage-Applications_108.html
Charaka Samhita Sutra sthana Chapter 15 Upakalpaniyaadhyaya
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micro teaching on communication m.sc nursing.pdf
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Native Bacillus licheniformis Protease
A protease is an enzyme that helps proteolysis: protein catabolism by hydrolysis of peptide bonds. The nave Bacillus licheniformis protease belongs to the serine endopeptidase subtilisin family, which breaks the peptide bond non-specifically under alkaline conditions. The enzyme is active in aqueous solutions and in some organic solvents such as dry octane. The protease is inactivated by serine active-site inhibitors, such as phenylmethylsulfonyl fluoride (PMSF) and diisopropylfluorophosphate. https://www.creative-enzymes.com/product/native-bacillus-licheniformis-protease_936.html
Proteinase K
Proteinase K is a stable and highly reactive serine protease. Evidence from crystal and molecular structure studies indicates the enzyme belongs to the subtilisin family with an active-site catalytic triad (Asp39-His69-Ser224). It is stable in a broad range of environments:pH, buffer salts, detergents (SDS), and temperature. In the presence of 0.1-0.5% SDS, proteinase K retains activity and will digest a variety of proteins and nucleases in DNA preparations without compromising the integrity of the isolated DNA. https://www.creative-enzymes.com/product/proteinase-k-from-tritirachium-album-limber-recombinant_3427.html
What Are Probiotics?
Probiotics are living microorganisms that co-exist with humans. Different from pathogenic microorganisms, probiotics are beneficial, and sometimes essential to health. For example, intake of probiotics can increase the number of beneficial bacteria in the intense, maintain the dynamic balance of intestinal flora, and enhance
gastrointestinal health. https://www.creative-enzymes.com/cate/probiotics_99.html
Tn5 Transposase
Tn5 Transposase is a hyperactive form of Tn5 transposase. This enzyme can be used to randomly insert Tn5 transposon into target DNA. Robust Tn5 Transposase recognizes inside end sequences, outside end sequences and mosaic end sequences of Tn5 transposon. https://www.creative-enzymes.com/product/tn5-transposase_8479.html
Enzymes in blood lipid metabolism
Blood lipids refer to a group of fatty substances present in the blood, mainly including cholesterol and triglycerides. There are generally two forms of cholesterols circulating in the bloodstream: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Abnormal lipid level in blood is always associated with a number of diseases, such as high blood pressure, coronary arteries, hypothyroidism, type 2 diabetes, obesity, pancreatitis, et al. https://diagnostic-enzymes.creative-enzymes.com/blood-lipids.html
Creative Enzymes's Diagnostic Enzymes for POC Biosensor
Point-of-care testing (POCT) refers to a group of immediate test approaches that are implemented near or at the site of patient care. Various portable and handheld instruments and test kits, or biosensors, have supplemented the POC. Creative Enzymes serves diagnostic enzyme products to optimize your POC biosensors. https://diagnostic-enzymes.creative-enzymes.com/poct-bio-sensor.html
Explore Enzymes Involved in Blood Lipid Metabolism at Creative Enzymes
Blood lipids refer to a group of fay substances present in blood, mainly including cholesterol and triglycerides. There are generally two forms of cholesterols circulating in bloodstream: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Abnormal lipid level in blood is always associated with a number of diseases, such as high blood pressure, coronary arteries, hypothyroidism, type 2 diabetes, obesity, pancreas, et al. https://diagnostic-enzymes.creative-enzymes.com/blood-lipids.html
Creative Enzymes: Antiallergic Probiotic Formula
Probiotics may exhibit antiallergic effects by degradation or structural modification of enteral antigens, stabilization of aberrant microbiota, improvement of the gut-barrier function, secretion regulation of pro-inflammatory mediators, and development of the immune system. https://probiotic.creative-enzymes.com/multi-strain-probiotics/antiallergic-formula.html
Enzyme immobilization
As an enzyme expert, Creative Enzymes is engaged in providing the best products and services for worldwide researchers, especially for enzymes modification. Immobilization is one of the most popular methods that were initially developed for biotechnology processes. Creative Enzymes offers enzyme immobilization services with reliable outcomes, improved performance, and surface analysis. https://www.creative-enzymes.com/service/Enzyme-Modification-By-Immobilization_366.html
Featured enzyme products for diagnostic use
Creative Enzymes is a worldwide leading company in diagnostic enzymes manufacturing and supply. We are committed to providing our customers with diverse enzyme products and custom enzyme-related services for medical and research diagnosis. Relying on our professional team and state-of-art technologies, we have gained solid reputation for having top of the line products and services.
Probiotics Powder
Creative Enzymes is a professional and experienced supplier of probiotics. In the past decade, Creative Enzymes mainly provides enzyme-related products and services. With the continuous expansion of business areas and scale, we have set foot in other areas and established a sound probiotic production and supply chain. Based on our high-quality products and services, as well as the unique advantages of large-scale production, our probiotic products are widely favored by industrial customers and scientific research customers.
Enzymes for Research and Diagnostic Use
Creative Enzymes is a world-wide provider of the best enzyme products. We now offer medical enzymes for pharmaceutical and diagnostic uses. In contrast to the industrial uses, enzymes of therapeutic uses are requested in relatively lower amounts but at a very high degree of purity and specificity. We have the capability to assure high-quality enzyme products based on our advanced equipment and professional techniques. In the past few years, the reliability of our products has been approved by thousands of customers and scientists. Specialized in the medical industry, the various kinds of enzyme products of Creative Enzymes will support your research in multiple areas.
Enzyme immobilization
As an enzyme expert, Creative Enzymes is engaged in providing the best products and services for worldwide researchers, especially for enzymes modification. Immobilization is one of the most popular methods that were initially developed for biotechnology processes. Creative Enzymes offers enzyme immobilization services with reliable outcomes, improved performance, and surface analysis.
Diagnostic enzymes
Creative Enzymes is a worldwide leading company in diagnostic enzymes manufacturing and supply. We are committed to providing our customers with diverse enzyme products and custom enzyme-related services for medical and research diagnosis. Relying on our professional team and state-of-art technologies, we have gained solid reputation for having top of the line products and services. https://diagnostic-enzymes.creative-enzymes.com/
Biocatalysis services at Creative Enzymes
Creative Enzymes has long demonstrated expertise and reliability in development and establishment of biocatalysis systems. We provide products, services, and consultation covering every step in the whole process of a biocatalyst development, including the design, modification, expression, purification, production, and validation of specific enzymatic or microbial systems that catalyze the desired reactions. https://www.creative-enzymes.com/service/Biocatalysis-Services_67.html
Introduction to Collagen and collagenase
Triplehelical domain of chicken sternum collagen type II. Gnd-HCl extracon, pepsin digeson, salt precipitaon, ion exchange chromatography, gel-filtraon. Nave type II collagen has posive effects on the treatment of early rheumatoid arthris. https://www.creative-enzymes.com/product/native-chicken-collagen-type-ii_3352.html
Featured Enzyme Products for Diagnosc Research
The abnormality in enzyme metabolism system leads to many metabolic diseases that are related to components of enzyme metabolism system. Enzymes have been widely used in clinical examinaon as the preferred markers in various disease states such as myocardial infarcon, jaundice, pancreas, cancer, neurodegenerave disorders, etc. They provide insight through the ability of diagnosis, prognosis, and assessment of response therapy. https://www.creative-enzymes.com/promotions/Featured-Enzyme-Products-For-Diagnostic-Use_6.html
Collagen and collagenase at Creative Enzymes
Triplehelical domain of chicken sternum collagen type II. Gnd-HCl extracon, pepsin digeson, salt precipitaon, ion exchange chromatography, gel-filtraon. Nave type II collagen has posive effects on the treatment of early rheumatoid arthris.
Collagen and collagenase
Triplehelical domain of chicken sternum collagen type II. Gnd-HCl extracon, pepsin digeson, salt precipitaon, ion exchange chromatography, gel-filtraon. Nave type II collagen has posive effects on the treatment of early rheumatoid arthris.
Enzymes in food industry
Enzymes are known to aid food processing in a wide variety of applications, for example manufacturing of cheese, vinegar and wine; leavening of bread; brewing of beer and so on. In these processes enzymes help to save energy and resources, as well as improve the overall efficiency. In many instances, the use of enzymes has been proved to decrease the volumes and toxicity of byproducts and effluents. Creative Enzymes provides a wide range of products including high purity enzymes and custom blends, which can be readily used in food and beverage processes. https://www.creative-enzymes.com/cate/Food-And-Beverage-Applications_108.html
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Physiology of Chemical Sensation of smell.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
BENIGN PROSTATIC HYPERPLASIA.BPH. BPHpdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Non-respiratory Functions of the Lungs.pdf
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
How to Give Better Lectures: Some Tips for Doctors
Talk given to Koronadal Internists Society, Marbel, South Cotabato as part of the Continuing Medical Education (CME) series.
Flu Vaccine Alert in Bangalore Karnataka
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Physiology of Special Chemical Sensation of Taste
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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Novas diretrizes da OMS para os cuidados perinatais de mais qualidade
Novas diretrizes da OMS para os cuidados perinatais de mais qualidadeProf. Marcus Renato de Carvalho
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Hemodialysis: Chapter 3, Dialysis Water Unit - Dr.Gawad
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Explore creative enzymes's enzyme products for triglyceride kit
- 1. Email: info@crea ve-enzymes.com Enzyme Products for Producing Triglyceride Kit A Triglyceride Kit is used to measure triglyceride concentra on in mammalian samples. The triglyceride assay is easy and sensi ve. Triglycerides are converted to free fa y acids and glycerol. Glycerol is then oxidized to generate a product that reacts with a probe to generate color and fluorescence. Crea ve Enzymes provides enzymes that are essen al to produce triglyceride kits. Learn More The measurement of triglyceride levels, in conjunc on with other lipid assays, is useful in the diagnosis of primary and secondary hyperlipoproteinemia, dyslipidemia, and triglyceridemia. Triglyceride assay kit provides a simple, reproducible, and sensi ve tool for assaying triglycerides in plasma, serum, cell lysates, and ssue homogenate samples. Crea ve Enzymes provides enzymes that can be used to produce triglyceride assay kits, including Lipoprotein Lipase (EC 3.1.1.34), Glycerol Kinase (EC 2.7.1.30), Glycerol-3-phosphate Oxidase (EC 1.1.99.5). Product Name Cat No.. EC No. Source Form Ac vity Na ve Pseudomonas sp. Lipoprotein lipase DIA-210 EC 3.1.1.34 Pseudomonas sp. Light brown amorphous powder, lyophilized >20U/mg-solid (containing approx. 80% of stabilizers) Na ve Microorganism Lipoprotein lipase DIA-211 EC 3.1.1.34 Microorganism Light brown amorphous powder, lyophilized >1.0U/mg- solid Chemically modified Pseudomonas species Lipoprotein Lipase DIA-282 EC 3.1.1.34 Pseudomonas species Brownish lyophilizate >10 U/mg lyophilizate Na ve Bovine Lipoprotein Lipase NATE- 0416 EC 3.1.1.34 Bovine milk ammonium sulfate suspension; Suspension in 3.8 M ammonium sulfate, 0.02 M Tris HCl, pH 8.0 > 2,000 units/mg protein (BCA) Na ve Burkholderia sp. Lipoprotein Lipase NATE- 0417 EC 3.1.1.34 Burkholderia sp. lyophilized powder > 50,000 units/mg solid lipoprotein lipase EXWM- 3460 EC 3.1.1.34 Liquid or lyophilized powder Glycerokinase from Cellulomonas sp. NATE- 0287 EC 2.7.1.30 Cellulomonas sp. Lyophilized powder containing phosphate buffer salts and sodium gluconate >20 U/mg- solid Glycerokinase from Microorganism DIA-149 EC 2.7.1.30 Microorganism Freeze dried powder >30 U/mg- solid Glycerol-3- phosphate oxidase from Pediococcus sp. DIA-154 EC 1.1.3.21 Pediococcus sp. Freeze dried powder >40 U/mg- solid (containing approx. 60% of stabilizers) Glycerol-3- phosphate oxidase from Microorganism DIA-200 EC 1.1.3.21 Microorganism Freeze dried powder >15 U/mg- solid (containing approx. 60% of stabilizers) Crea ve Enzymes also provides other enzyme products for diagnos c uses. Please contact us for any product needs. Learn More Contact Informa on Email: info@crea ve-enzymes.com 45-1 Ramsey Road, Shirley, NY 11967, USA Tel: 1-631-562-8517 diagnos c-enzymes.crea ve-enzymes.com Fax: 1-631-938-8127