This document discusses the challenges of measuring real-world driving emissions (RDE) due to short-duration transient spikes in pollution. Portable emissions measurement systems (PEMS) are too slow to accurately measure these spikes, with response times of seconds, while Cambustion emissions analyzers can respond within milliseconds. Fast-response analyzers were able to precisely measure hydrocarbon spikes during a cold start and capture individual cylinder exhaust events. Testing of vehicles in London identified specific speed bumps and traffic conditions as hot spots causing higher-than-limit nitrogen oxide emissions. Fast analyzers allow correlating transient emissions to engine parameters and identifying solutions.