Calories, Carbs, or Quality? What Matters Most for Body WeightInsideScientific
To learn more and watch the webinar, visit:
https://insidescientific.com/webinar/calories-carbs-quality-what-matters-most-for-body-weight-obesity-series-2020
Eating fat makes you fat. No, eating carbs makes you fat. Actually, it’s a simple equation relating calories in and calories out. Such endless debates about putative dietary culprits or cures for obesity have led to widespread public confusion and mistrust in nutrition science. But what is the truth?
During this webinar, Dr. Kevin Hall discusses the physiology of body weight regulation and how we adapt to various changes in diet, including the amount of calories, carbs versus fat, as well as differences in diet quality varying in the amounts of “ultra-processed” foods. Understanding the dynamics of human body weight change has important consequences for conditions such as obesity, diabetes, cardiovascular disease, starvation, and wasting syndromes such as anorexia nervosa and cancer cachexia.
Key discussion topics include:
– Understand how body weight is regulated as part of a negative feedback control system
– Understand how the body responds to diets with wide variation in their ratio of carbohydrate to fat
– Understand how the body responds to diets varying in quality as determined by their amount of ultra-processed foods
Dr. John Patience - A Critical Look at the Science Underlying Feed EfficiencyJohn Blue
A Critical Look at the Science Underlying Feed Efficiency - Dr. John Patience, Iowa State University, from the 2012 Allen D. Leman Swine Conference, September 15-18, St. Paul, Minnesota, USA.
Animal Model Selection, Study Design and Current Trends in Preclinical Obesit...InsideScientific
During this presentation, Dr. Fred Beasley gives a broad-level overview of the factors to consider when deciding on an appropriate preclinical rodent model for studying obesity and its treatments. It features an overview of trends in obesity and associated illnesses, and the role of pharmacological intervention. Dr. Beasley discusses criteria for establishing a study’s aims and review commonly used rodent models obesity, addressing both genetically inherited and diet-induced obesity. The webinar concludes with additional considerations for improving your study design.
Key topics include…
- An introduction to the role of pharmacological intervention in treating obesity
- A guide to establishing study aims for obesity research
- An overview of commonly used rodent obesity models (diet and genetic)
- Additional considerations for obesity research study design
Key methods reviewed include…
Pharmacotherapy, diet induced obesity, Western-style diet, monogenic obese rodents, polygenic obese rodents, NAFLD activity score
Anti obesity screening models to perform the screening of new molecules/compounds to develop a new potential therapeutic drug for the treatment of central obesity.
Some stimuli, including specific foods, seem to have enough particularities to make a difference even if their potential to exert an influence a priori appears to be limited. This is the case of yogurt whose consumption is low relative to the amount of daily food consumed but that has been shown to be independently related to reduced body weight and fat. Numerous factors may explain a beneficial effect of yogurt on body weight stability and metabolic fitness. Cohort studies show that the consumption of dairy including yogurt is related to a reduced intake of high fat-high sugar foods, suggesting that the benefits of dairy food may be due to a decrease in the potential negative effects of unhealthy eating. The ability of yogurt to promote a negative energy balance is also likely explained by the satiating and thermogenic effects of some of its nutrients, e.g. calcium and proteins, via mechanisms involving gut hormones. Yogurt has a matrix that can accommodate structural changes affecting energy intake independently of its nutrient content. For instance, we recently demonstrated that the increase in the whey/casein ratio in a yogurt matched for volume and energy and protein content as a control yogurt significantly decreased subsequent energy intake to a much greater extent than the energy content of the yogurt preload. The presence of bacteria in yogurt represents another factor that may explain the effects of yogurt consumption on energy balance and its components. In this regard, recent data suggest that the supplementation of some probiotics facilitates appetite control and accentuates body weight loss in the context of a weight-reducing program. Finally, our recent analyses of relevant data in the Quebec Family Study reveal that yogurt consumption may be the signature of a global healthy lifestyle and food-related personal profile. Female yogurt consumers are more physically active, report a reduced percent energy intake as fat and display a lower disinhibition score than non-yogurt consumers. Taken together, yogurt has numerous features that may globally explain the decreased proneness of yogurt consumers towards excess body fat.
Heterogeneity and Crosstalk of Human Brown Adipose TissueInsideScientific
To learn more and watch the webinar, go to:
https://insidescientific.com/webinar/heterogeneity-and-crosstalk-human-brown-adipose-tissue-obesity-series-2020
Adipose tissues contain lipid-filled adipocytes but are also composed of several other cell types including adipogenic progenitors, endothelial cells, immune cells and neuronal cells. Brown adipose tissue (BAT) contains thermogenic adipocytes which produce heat in response to cold, an energy-consuming process. Today, it is well established that adipose tissue function is highly dependent on the plasticity of the tissue due to the interaction of different cell types present within the tissue. In addition, the function of adipose tissue is controlled by secreted factors, called adipokines or batokines. Some of these cytokines affect nearby cells within the adipose tissue while others are secreted into the circulation for communication at the organ level.
In this exclusive live webinar, Camilla Schéele, Associate Professor at The Novo Nordisk Foundation Center for Basic Metabolic Research in Copenhagen, Denmark and Christian Wolfrum, Professor at ETH Zürich in the Department of Health Science and Technology in Zürich, Switzerland discuss broader aspects of brown adipose tissue and share late-breaking research relating to the role of BAT in whole body metabolic regulation.
Calories, Carbs, or Quality? What Matters Most for Body WeightInsideScientific
To learn more and watch the webinar, visit:
https://insidescientific.com/webinar/calories-carbs-quality-what-matters-most-for-body-weight-obesity-series-2020
Eating fat makes you fat. No, eating carbs makes you fat. Actually, it’s a simple equation relating calories in and calories out. Such endless debates about putative dietary culprits or cures for obesity have led to widespread public confusion and mistrust in nutrition science. But what is the truth?
During this webinar, Dr. Kevin Hall discusses the physiology of body weight regulation and how we adapt to various changes in diet, including the amount of calories, carbs versus fat, as well as differences in diet quality varying in the amounts of “ultra-processed” foods. Understanding the dynamics of human body weight change has important consequences for conditions such as obesity, diabetes, cardiovascular disease, starvation, and wasting syndromes such as anorexia nervosa and cancer cachexia.
Key discussion topics include:
– Understand how body weight is regulated as part of a negative feedback control system
– Understand how the body responds to diets with wide variation in their ratio of carbohydrate to fat
– Understand how the body responds to diets varying in quality as determined by their amount of ultra-processed foods
Dr. John Patience - A Critical Look at the Science Underlying Feed EfficiencyJohn Blue
A Critical Look at the Science Underlying Feed Efficiency - Dr. John Patience, Iowa State University, from the 2012 Allen D. Leman Swine Conference, September 15-18, St. Paul, Minnesota, USA.
Animal Model Selection, Study Design and Current Trends in Preclinical Obesit...InsideScientific
During this presentation, Dr. Fred Beasley gives a broad-level overview of the factors to consider when deciding on an appropriate preclinical rodent model for studying obesity and its treatments. It features an overview of trends in obesity and associated illnesses, and the role of pharmacological intervention. Dr. Beasley discusses criteria for establishing a study’s aims and review commonly used rodent models obesity, addressing both genetically inherited and diet-induced obesity. The webinar concludes with additional considerations for improving your study design.
Key topics include…
- An introduction to the role of pharmacological intervention in treating obesity
- A guide to establishing study aims for obesity research
- An overview of commonly used rodent obesity models (diet and genetic)
- Additional considerations for obesity research study design
Key methods reviewed include…
Pharmacotherapy, diet induced obesity, Western-style diet, monogenic obese rodents, polygenic obese rodents, NAFLD activity score
Anti obesity screening models to perform the screening of new molecules/compounds to develop a new potential therapeutic drug for the treatment of central obesity.
Some stimuli, including specific foods, seem to have enough particularities to make a difference even if their potential to exert an influence a priori appears to be limited. This is the case of yogurt whose consumption is low relative to the amount of daily food consumed but that has been shown to be independently related to reduced body weight and fat. Numerous factors may explain a beneficial effect of yogurt on body weight stability and metabolic fitness. Cohort studies show that the consumption of dairy including yogurt is related to a reduced intake of high fat-high sugar foods, suggesting that the benefits of dairy food may be due to a decrease in the potential negative effects of unhealthy eating. The ability of yogurt to promote a negative energy balance is also likely explained by the satiating and thermogenic effects of some of its nutrients, e.g. calcium and proteins, via mechanisms involving gut hormones. Yogurt has a matrix that can accommodate structural changes affecting energy intake independently of its nutrient content. For instance, we recently demonstrated that the increase in the whey/casein ratio in a yogurt matched for volume and energy and protein content as a control yogurt significantly decreased subsequent energy intake to a much greater extent than the energy content of the yogurt preload. The presence of bacteria in yogurt represents another factor that may explain the effects of yogurt consumption on energy balance and its components. In this regard, recent data suggest that the supplementation of some probiotics facilitates appetite control and accentuates body weight loss in the context of a weight-reducing program. Finally, our recent analyses of relevant data in the Quebec Family Study reveal that yogurt consumption may be the signature of a global healthy lifestyle and food-related personal profile. Female yogurt consumers are more physically active, report a reduced percent energy intake as fat and display a lower disinhibition score than non-yogurt consumers. Taken together, yogurt has numerous features that may globally explain the decreased proneness of yogurt consumers towards excess body fat.
Heterogeneity and Crosstalk of Human Brown Adipose TissueInsideScientific
To learn more and watch the webinar, go to:
https://insidescientific.com/webinar/heterogeneity-and-crosstalk-human-brown-adipose-tissue-obesity-series-2020
Adipose tissues contain lipid-filled adipocytes but are also composed of several other cell types including adipogenic progenitors, endothelial cells, immune cells and neuronal cells. Brown adipose tissue (BAT) contains thermogenic adipocytes which produce heat in response to cold, an energy-consuming process. Today, it is well established that adipose tissue function is highly dependent on the plasticity of the tissue due to the interaction of different cell types present within the tissue. In addition, the function of adipose tissue is controlled by secreted factors, called adipokines or batokines. Some of these cytokines affect nearby cells within the adipose tissue while others are secreted into the circulation for communication at the organ level.
In this exclusive live webinar, Camilla Schéele, Associate Professor at The Novo Nordisk Foundation Center for Basic Metabolic Research in Copenhagen, Denmark and Christian Wolfrum, Professor at ETH Zürich in the Department of Health Science and Technology in Zürich, Switzerland discuss broader aspects of brown adipose tissue and share late-breaking research relating to the role of BAT in whole body metabolic regulation.
This study is the first one to show the effect of dietary intervention in the secondary prevention of CHD. It is meal pattern study even if very often labelled as sole fat modification study
Nutritional Recommendations for a Sustainable Bone and Muscle Health, René Ri...Yogurt in Nutrition #YINI
The WCO continues to be the primary forum for scientists to focus on the impact of lifestyle on bone health in general. The satellite symposium organized by YINI in particular featured many global comparisons in diet and the effect on bone. As Western diet permeates more of the globe and the population continues to grow, it is meaningful to study the impact of these changes on bone health as diet is one of the few major modifiable factors which in turn affects healthcare costs. Calcium, vitamin D, and protein intake continued to dominate the discussion. The symposium offered an opportunity to learn about theories and data in nutritional research concerning bone as well as methodological approaches to classify diets. The slideshow allow the reader to capture the new messages and to analyze the new scientific data presented by Professor Rene Rizzoli (Switzerland) in this field.
Yogurt consumption for a healthier diet and lifestyle: overview from cohorts ...Yogurt in Nutrition #YINI
Yogurt is generally considered as a healthy food because of its nutrient composition, its profile of fermented food, and its link with an improved metabolic fitness. Population studies show that yogurt consumers report a greater intake of some nutrients,
e.g. calcium and protein, and fruits and vegetables compared to non-consumers. This is concordant with recent data demonstrating that diet quality is improved in yogurt consumers. Other cohort studies have shown that yogurt consumption is
associated with a reduced body weight over time. Our research experience with the Quebec Family Study reveals that yogurt consumption might be the “signature of a healthy lifestyle”. Indeed, female yogurt consumers report a better macronutrient
composition of the diet than non-consumers; they are also more physically active and display feeding behaviors which are more compatible with body weight stability. This agrees with results of the Infogene Study demonstrating that yogurt consumers
are more prone to adhere to a Prudent dietary pattern whereas non-consumers tend to exhibit a Western pattern. In summary, currently available cohort studies tend to show that yogurt consumption is associated with a healthy eating pattern
and lifestyle.
Bariatric surgery is one of the most effective treatments of obesity in adults. Unlike many drugs prescribed for the treatment of obesity, bariatric surgery has a broad range of effects, including physiological impact on the gastrointestinal tract and gut microbiota.
In this final installment of our Obesity 2020 webinar series, Dr. Lee Kaplan discusses late-breaking research and reviews various mechanisms of action of bariatric and metabolic surgery and how they affect the regulation of energy balance and metabolic function.
World Health Organization (WHO) defines overweight and obesity as "Abnormal or excessive fat accumulation that presents a risk to health". Body Mass Index (BMI)- ratio of person's weight (in kilograms) to square of height (in meters) - is the tool to measure obesity.
This study is the first one to show the effect of dietary intervention in the secondary prevention of CHD. It is meal pattern study even if very often labelled as sole fat modification study
Nutritional Recommendations for a Sustainable Bone and Muscle Health, René Ri...Yogurt in Nutrition #YINI
The WCO continues to be the primary forum for scientists to focus on the impact of lifestyle on bone health in general. The satellite symposium organized by YINI in particular featured many global comparisons in diet and the effect on bone. As Western diet permeates more of the globe and the population continues to grow, it is meaningful to study the impact of these changes on bone health as diet is one of the few major modifiable factors which in turn affects healthcare costs. Calcium, vitamin D, and protein intake continued to dominate the discussion. The symposium offered an opportunity to learn about theories and data in nutritional research concerning bone as well as methodological approaches to classify diets. The slideshow allow the reader to capture the new messages and to analyze the new scientific data presented by Professor Rene Rizzoli (Switzerland) in this field.
Yogurt consumption for a healthier diet and lifestyle: overview from cohorts ...Yogurt in Nutrition #YINI
Yogurt is generally considered as a healthy food because of its nutrient composition, its profile of fermented food, and its link with an improved metabolic fitness. Population studies show that yogurt consumers report a greater intake of some nutrients,
e.g. calcium and protein, and fruits and vegetables compared to non-consumers. This is concordant with recent data demonstrating that diet quality is improved in yogurt consumers. Other cohort studies have shown that yogurt consumption is
associated with a reduced body weight over time. Our research experience with the Quebec Family Study reveals that yogurt consumption might be the “signature of a healthy lifestyle”. Indeed, female yogurt consumers report a better macronutrient
composition of the diet than non-consumers; they are also more physically active and display feeding behaviors which are more compatible with body weight stability. This agrees with results of the Infogene Study demonstrating that yogurt consumers
are more prone to adhere to a Prudent dietary pattern whereas non-consumers tend to exhibit a Western pattern. In summary, currently available cohort studies tend to show that yogurt consumption is associated with a healthy eating pattern
and lifestyle.
Bariatric surgery is one of the most effective treatments of obesity in adults. Unlike many drugs prescribed for the treatment of obesity, bariatric surgery has a broad range of effects, including physiological impact on the gastrointestinal tract and gut microbiota.
In this final installment of our Obesity 2020 webinar series, Dr. Lee Kaplan discusses late-breaking research and reviews various mechanisms of action of bariatric and metabolic surgery and how they affect the regulation of energy balance and metabolic function.
World Health Organization (WHO) defines overweight and obesity as "Abnormal or excessive fat accumulation that presents a risk to health". Body Mass Index (BMI)- ratio of person's weight (in kilograms) to square of height (in meters) - is the tool to measure obesity.
Das ist ein Vortrag, den Dr. Clarence P. Davis im Jahre 2007 im Rahmen eines Anti-Aging Kongresses in Paris gehalten hat. Er beinhaltet theoretisches Basis- und Hintergrundswissen zu den verschiedenen Diaettypen, sowie einige praktische Beispiele aus dem aerztlichen Alltag. Der Vortrag ist auf einem hohen Niveau und richtet sich ausschliesslich an professionelle Leser mit fundierten Vorkenntnissen.
Protein Requirements for Kidney Transplant Candidates, Recipients and DonorsJamieMiller341511
this slide deck reviews the roles and sources of protein as well as the protein requirements of pre-modality CKD patients, hemodialysis and peritoneal dialysis patients awaiting transplant, as well as transplant recipients and living kidney donors
Skipping your breakfast is stupid & consume sufficient proteins in the morning.Wouter de Heij
The addition of a protein-rich breakfast tot improve appetite control and combat obesity
Heather J. Leidy, PhD
IFT 2012
(with permission of H.J. Leidy)
For more information, visit https://www.timberlandmedical.com
This presentation is by Dr LO SIAW PING, a visiting dietician at Timberland Medical Centre
Timberland Medical Centre is a private hospital that has been in operation since 1994. We are strategically located at the 3rd Mile roundabout on Jalan Rock, Kuching, Sarawak, East Malaysia. Our hospital is 10 minutes from the Kuching International Airport and 15 minutes from the Central Bus Terminal. We continually seek to improve and upgrade our services and facilities, as we strive to provide the best medical care for our patients and customers.
Weight Loss and Pharmanex TR90: What You Need to KnowLouis Cady, MD
Dr. Cady reviews the science and the facts of weight gain, weight loss, and the new genomically focused weight loss program from Pharmanex: TR90. In this program, Dr. Cady relentlessly dissects the errors of the "low fat" way to eat, targets high glycemic eating and protein deficient diets as the main culprits in our society's weight gain, and proposes a common-sense and rational way to eat to achieve any of the following goals: (a) not gain any more weight, (b) maintain your current weight, (c ) lose weight.
The genomic science behind the technology used by Pharmanex to develop TR-90 is reviewed. TR90 is the only genomically focused, nutritionally sound weight management available for sale today. The genomic science behind this product is established. Multiple scientific papers (one of which is referenced in this presentation) unequivocally show that what you eat in your diet alters gene expression.
As of the release of this slide deck on 4/19/2014, the three month TR90 system will only be available for sale in the US for one day on April 23rd at 11 a.m. CST. It is estimated that the entire manufactured run available for the US will sell out in 60 - 90 minutes. It will not be available for sale in this country for six months after this date. Please contact the office at Cady Wellness Institute if you are interested in securing a three month supply. (812) 429-0772.
Learn from Bethany Doerfler, MS, RD, LDN, a registered dietitian whose clinical practice and research focuses on providing wellness-based medical nutrition therapy for digestive disorders and allergic bowel diseases. She currently practices in the Division of Gastroenterology and Hepatology at Northwestern Medicine in Chicago, IL. She is the first dietitian to be fully integrated into a gastroenterology division for both research and patient care. This presentation is optimized for Scleroderma patients to learn about their diet options to improve scleroderma symptoms and their gut health.
The lecture of Drs. Cady and Gabhart, presented at the Evansville Public LIbrary on both common-sensical as well as more endocrinological refined methods for achieving weight loss.
Similar to Total Well Being Diet: - from lab bench to kitchen table (20)
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
4. CSIRO Lower Carbohydrate
Higher Protein Pattern
Extensively clinically evaluated
Efficacy
Fat loss
Heart health benefits
Reduces glucose and insulin levels
Improves vitamin/mineral status
Safety
Bone
Renal
Liver
Nutritionally balanced
5. Research origins – Role of Proteins
1999 2000 2001 2002 2003 2005-11
• CSIRO • Co-funded • Co-funded • Sponsored • Sponsored • Sponsored
• Co-funded • Sponsored • Sponsored
• Co-funded • Co-funded
• Dairy Australia
• CSIRO X4
• Meat & Livestock Australia
• Goodman Fielder
• National Heart Foundation
• National Centre of Excellence in Functional Foods
• National Health and Medical Research Council
• Diabetes Australia Research Trust
• Australian Egg Corporation LTD
• University of Adelaide
• Pork CRC
7. High Protein Diets in Energy Restriction
enhances weight loss
(Skov et al. 1999; Baba et al. 1999, layman 2003 )
promotes favourable changes in body
composition
(Skov et al. 1999; Laymen et al. 2003; Parker et al. 2002, Noakes 2005)
beneficial effects on heart disease risk
factors
insulin sensitivity (Baba et al. 1999; Layman 2003; Piatti et al. 1994)
glucose/insulin profiles (Farnsworth et al. 2003, Gannon et al 2003)
triglyceride reduction (Layman, 2003; Farnsworth 2003, Gannon 2003 )
8. High Protein Moderate Carb Diets
Noakes, Keogh, Foster, Clifton et al AJCN 2005
*
*
*
High protein moderate carb patterns for weight loss improve fat loss
and triglyceride reduction in people with high triglycerides
9. Abdominal Fat Mass
Change in Abdominal Fat Mass1
0
abdominal fatt loss (kg)
-0.1 1
-0.2
-0.3
-0.4 HP
-0.5
HC
-0.6
-0.7
-0.8 1
Significant diet X time interaction P=0.02
HP -0.76±0.38 kg vs HC, -0.56±0.36 kg
10. Glucose Response to Test Meals
9
Diet effect p = 0.020
8
Glucose (mMol/l)
7 High Protein
6 High carb
5
4
0 30 60 120 180
Time (min)
F arnsworth et al AJCN 2003
11. Insulin Response to Test Meals
Diet effect p < 0.05
140
120
100
Insulin (mU/l)
80 High Protein
60 High Carb
40
20
0
0 30 60 120 180
Time (min) F arnsworth et al AJCN 2003
12. High Protein Diet using Partial Meal Replacements
in Type 2 Diabetes
Results at 12 weeks 5.5MJ
104g Protein
9% weight loss 25g Fat
“ waist circumference (9%) 114g Carbohydrate
“ blood pressure (7.8/3.9 mmHg) 28g Fibre
“ fasting glucose (21%)
“ HbA1c (16%) Traditional cardiovascular risk factors
“ insulin resistance (48%)
“ triglyceride (34%)
“ total cholesterol (10%)
“ LDL-cholesterol (8%)
“ oxidative stress - MDA (26%)
NO change in endothelial function (FMD)
13. Key features
higher protein
daily self monitoring
structured eating plan
extensive suggestions
for menus and recipes
encourages exercise
TWD is NOT the only approach to weight
management but represents a scientifically
supported option
15. Key Foods on CSIRO Diet
PROTEIN FOODS WHOLEGRAIN BREAD
DAIRY FOODS, 2 slices per day
• 3 serves per day HIGH-FIBRE CEREAL
MEAT/CHICKEN/FISH 1 serve per day
• 200g dinner FRESH FRUIT
CHICKEN/FISH/EGGS 2 serves per day
• up to100g/day at lunch VEGETABLES
at least 2.5 cups per day
OIL/MARG
3 teaspoons per day
INDULGENCE FOODS eg alcohol
2-4 times per week
17. Volume of Books Sold Weekly
No 1 19/52 weeks
Top 10 50/52 weeks
May May
2005 2006
Total sold in Australia
>1,000,000
18. TWD Consumer Study
• Objectives of the study:
•To see how TWD has contributed to CSIRO’s aim to
aid in a positive change to Australian eating culture
and consumer nutrition. Specifically to answer
questions such as:
•Are people aware of the TWD? How did they find
out about it?
•Do they use the book? In what ways?
•Has the book changed their behaviour in any way
and how?
19. Methodology
• Representative population survey outsourced to external agency
(Inside Story) conducted September 2006 (pre book 2 launch)
• telephone
• online
Data weighted to population in line with ABS statistics.
Data from the online sample is similar to that of the telephone survey.
Telephone Online TOTAL
10 minutes 15 minutes
Metro 702 2824 3526
Regional 298 1202 1500
TOTAL 1000 4026 5026
20. Awareness
Awareness is high – messages about
TWD have reached two thirds of the
Total aware: population …including those not
65% concerned with their weight
Overall those aware are likely to be
female, 60+ or interested in losing
weight. However, even those that are
not concerned with losing weight have
high awareness. All demographics
have awareness over 50%
N=5026
Gender Age Current attitude towards
weight loss
Total Male Female 18-24 25-39 40-59 60+ Lose Maintain Don’t Want to
care
Aware 65% 57% 72% 53% 65% 67% 71% 76% 75% 68% 71%
21. What effects has TWD had on quality of life?
Worsened No change Improved a little Improved a lot
n = 504
Q18. Since using TWD, what have been
the effects or changes you’ve noticed on
the following factors in your life?
22. Can you please tell me your impressions
of CSIRO TWD?
Not really, definitely not Sort of Definitely Don’t know
Eating plan for 4% 10%
overall wellbeing
4% 10%
Healthy way of eating
14%
Long term lifestyle pattern 6%
Weight loss diet 13% 12%
Eating plan I trust 11% 24%
Protein based diet 15% 45%
Meat based diet 29% 35%
Low carb diet 18% 47%
n = 3326 – all aware
23. How much weight loss?
Average amount
of weight lost 6.1kg
Q16b. Approximately how
much weight have you (conservative estimate)
lost since using TWD?
24. What effects has TWD had?
Worsened Improved a little Improved a lot little
No change Improved a Improved a lot
n = 504
25. What effects has TWD had?
Worsened No change Improved a little Improved a lot
Positive
result
n = 504
Q18. Since using TWD, what
have been the effects of changes
you’ve noticed on the following
factors in your life?
26. Psychological affects
Worsened No change Improved a little Improved a lot
n = 504
Q18. Since using TWD, what
have been the effects of changes
you’ve noticed on the following
factors in your life?
27. Physical effects
Worsened No change Improved a little Improved a lot
n = 504
Q18 Since using TWD, what have
been the effects of changes
you’ve noticed on the following
factors in your life?
28. The biggest change to people’s lives
n = 349
Q17. And what is the biggest change
you have made as a result of TWD?
29. Other changes to people’s lives
Over a third have lost weight
. This represents 4% of the total
sample i.e. all Australians
This group are more likely
to be made up of those
trying to lose weight
and those in
n = 504 - users
regional areas
Q16a.Which of the following
changes have you made as a
result of TWD?
30. Projected impacts of TWD
CSIRO Total Wellbeing Diet- has sold
over 1 million copies
Over 500,000 people projected to have
lost 6 kg average
Estimated health cost savings $43m per
annum assuming weight loss
maintenance.
1 in 6 adult Australians have impaired
glucose regulation
A 4kg weight loss can prevent the
development of type 2 diabetes in 60%
of susceptible people after 4 years
Estimated that TWD could have delayed
or prevented type 2 diabetes
conservatively in 25,000 people