The document discusses the role of universities in the Adriatic-Ionian macro-region for local and regional development. It argues that universities should (1) recognize their role in scientific research, education, and lifelong learning to address common issues across the macro-region, (2) establish cooperation agreements for joint agencies and projects in areas of shared interest, and (3) strengthen training through double degree programs at both the graduate and PhD levels to train regional development experts. The goal is for universities to help drive integration, address knowledge gaps, and support local communities through education, research, and partnerships across the Adriatic-Ionian region.