The SOLUCION TB Program in Mexico from 2004-2012 worked to strengthen tuberculosis control through several phases. It began with dedicated programs in two states, then expanded nationwide working in 13 states and 35 municipalities. Key strategies included advocacy, communication, social mobilization, and training healthcare workers. Results showed improved TB treatment success rates and collaboration between health agencies and communities. Later phases addressed comorbidities of TB-HIV/AIDS and TB-diabetes by improving testing, diagnosis, and referrals. The program strengthened public health systems and informed national TB strategies in Mexico.