Within a few million light-years of the Milky Way are several dozen galaxies that make up the Local Group, including the Andromeda Galaxy. The Andromeda Galaxy is the largest galaxy in the Local Group and shares many similarities with the Milky Way, such as both being large spiral galaxies of roughly the same age. Other notable galaxies in the Local Group include the Large and Small Magellanic Clouds, which orbit the Milky Way.
One of my friends Mr. Ajit Gadre has sent me this fantastic PPT. I liked it so I am sharing this. Many thanks to him. This shows how small, tiny and नगण्य
we are in this Universe.
One of my friends Mr. Ajit Gadre has sent me this fantastic PPT. I liked it so I am sharing this. Many thanks to him. This shows how small, tiny and नगण्य
we are in this Universe.
For your viewing pleasure. Worth downloading to get the full effect of the presentation.
I receive several PowerPoint presentations through e-mail, so I thought I'd share them. I just post them. I didn't creat them :)
www.PowerLegacy.Com
We have the best yard shed designs available anywhere. All our yard shed designs come complete from start to finish, and include material lists, detailed diagrams, and explicit step by step instructions.
For your viewing pleasure. Worth downloading to get the full effect of the presentation.
I receive several PowerPoint presentations through e-mail, so I thought I'd share them. I just post them. I didn't creat them :)
www.PowerLegacy.Com
We have the best yard shed designs available anywhere. All our yard shed designs come complete from start to finish, and include material lists, detailed diagrams, and explicit step by step instructions.
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Aspergillosis Patient Support Meeting July 2011 - Sue HowardGraham Atherton
2 hour support meeting for patients & carers that live with aspergillosis.
Main speaker is Dr Sue Howard of Manchester University and the National Aspergillosis Centre
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
2. What other galaxies are near the Milky Way
galaxy?
“Near” is a relative term when it comes to
galaxies. Within a few million light-years of the
Milky Way are several dozen galaxies that make
up the Local Group. Some of those galaxies,
such as the Sagittarius dwarf galaxy, are
almost in physical contact with the Milky Way’s
outskirts.
3. What is the largest galaxy in the Local
Group?
The Andromeda galaxy, which is slightly
larger than the Milky Way, is the largest galaxy in
the Local Group. Andromeda is also known as
Messier 31, or M31, because it is the thirty-first
object listed in the famous catalog of night-sky
objects compiled by Charles Messier in 1774.
4.
5. When was Andromeda discovered?
According to French astronomer Charles Messier, who
put the great nebula in Andromeda as the thirty-first
object in his famous Messier catalog, the first European
astronomer who discovered Andromeda was Simon
Marius. Marius observed the Andromeda galaxy through a
telescope in 1612; he was probably the first person to do
so. According to non- European records, however, the
ancient Persian astronomer Al-Sufi observed the
Andromeda galaxy as early as 905 C.E. without the aid of a
telescope. Al-Sufi called it the “little cloud.”
6. How similar is the Andromeda galaxy to our
own?
The Andromeda galaxy shares many
characteristics with the Milky Way. It is a large
spiral galaxy, like the Milky Way; it appears to
be roughly the same age as the Milky Way; and it
contains many of the same types of objects
as the Milky Way, including a
supermassive black hole at its center.
Andromeda is somewhat larger than the Milky Way
7. What other galaxies populate the Local
Group of galaxies?
The largest of these Local Group dwarf
galaxies are the Large Magellanic Cloud and
the Small Magellanic Cloud, which orbit the
Milky Way, and Messier 32 and Messier 33,
which orbit Andromeda. Other wellknown
Local Group dwarfs include IC 10, NGC 205,
NGC 6822, and the Sagittarius dwarf galaxy.
The table below lists some of the Local
Group galaxies.
8.
9.
10. What important astronomical event occurred
recently in the Large Magellanic Cloud?
On February 23, 1987, Supernova
1987A appeared in the Large Magellanic
Cloud. It was discovered almost immediately
by two astronomers, Ian Shelton and
Oscar Duhalde, at Las Campañas
Observatory in Chile.
11. What is the Large Magellanic Cloud?
The Large Magellanic Cloud, or LMC, is the
largest dwarf galaxy that orbits our own
Milky Way galaxy. It is an irregular disk galaxy that
is similar in shape to the Milky Way, and we see it
sort of edge on, so it looks like an oblong-shaped
cigar to viewers on Earth. The LMC is about 30,000
light-years across and 170,000 light-years away
from Earth. It is named after the explorer
Ferdinand Magellan, who in 1519 was the first
European to record its existence.
12. What is the Small
Magellanic Cloud?
The Small Magellanic Cloud (SMC), like
its bigger compatriot the Large Magellanic
Cloud (LMC), is a small irregular galaxy
that orbits the Milky Way galaxy. It is a
roughly disk-shaped galaxy about 20,000
light-years across and about 200,000 light-
years away.
13. Located in the Small
Magellanic Cloud,
N81 is a cluster of
about 50 stars within a
mere 10 light-year
distance of one
another. Such unusual
phenomena within both
the Large
and Small Magellanic
Clouds make them
irregular galaxies.