The cure aims at hacking The Cure to learn concepts of biology associated with cancer.

1. The Cure
@genegame
a scientific discovery game in the class

2. The Cure: A scientific game
- Exploration of data
related to cancer
prognosis
- Genes whose expression
is modified in patients are
proposed
- Players explore the
combinatorial issue

3. The Cure: A scientific game
Players can:
- read text extracted from
genomic databases
- make hypotheses

4. The Cure: adaptation to the class
- Students are encouraged to
explore real the genomic
data
- Creation of a “second
level” allowing free creation
of decision trees

5. The game is fun, motivating
“What is very nice is that we have access to the real data
base of searchers, and that we know that we are actually
really helping people to search for solutions for cancers.”
Intersection of game based learning and learning through
research

6. Results obtained by students
Functions identified:
apoptosis, calcium binding, cell cycle, DNA binding, RNA
binding, DNA replication, cell growth, Tyrosine kinase
receptors, blood vessel growth and gene expression
regulation, cell membrane structure.
Potential for collective intelligence as all did not find the
same functions.

7. Adaptations proposed/inspired by
students
- Improved description/tutorial
- feedback on functions associated with each level
- creation of a rubric

8. Further developments
- Social aspect (engagement and collective intelligence)
- Improve tutorial
- Identify partners to assess learning transfer and retention
- Open badges to validate work performed

9. Team
Ben Good (Scripps, CA, USA)
→ Creation of the game
Antoine Taly (Université Paris Descartes)
→ Adaptation to teaching
Pierre-Luc Satin (FDV Bachelor program, Paris Descartes)
→ test / game design feedback
Matthieu Chavent (Oxford, UK)
→ preparation of tests in Oxford
Marc Baaden (CNRS)
→ tests