This document summarizes efforts in Wales to address loneliness and social isolation among older adults in care homes through intergenerational programs. It notes rising antidepressant prescriptions and details a project that paired 64 care homes with 72 schools for activities like baking competitions, visits, and pen pals. Evaluations found benefits like reduced aggressive behaviors and 50% lower antipsychotic use among residents. Moving forward, the project aims to twin more homes and schools, expand pen pal programs, share its intergenerational strategy toolkit, and further reduce antipsychotic prescribing through meaningful intergenerational activities.