Presentation from the UK NSC conference in December 2016 about the recommendation on the use of pulse oximetry screening for critical congenital heart disease in newborns.
This document summarizes a presentation about the UK National Screening Committee (UK NSC). It discusses the committee's role in advising on screening programs, challenges like ensuring evidence-based decisions and effective communication, and the vision for continuing to provide high-quality independent advice on screening to maximize benefits and minimize harms. Key areas covered include screening criteria, evidence review processes, stakeholder engagement, and evaluating existing and new screening proposals.
Screening for critical_congenital_heart_defects_with_pulse_oximetry_uk_perspe...eram sid
This document discusses pulse oximetry screening for critical congenital heart defects. It provides background on studies showing pulse oximetry can detect many cases of critical CHD before clinical symptoms appear. While early studies had small sample sizes, later studies of over 100,000 babies screened in the UK found a sensitivity of 83.6% and low false positive rate of 0.3%. The document examines different screening protocols and their effectiveness. It concludes that pulse oximetry screening is a feasible, acceptable, and cost-effective approach to reducing the diagnostic gap for critical CHD.
Effect of Continuous Infusion of Hypertonic Saline vs Standard Care on 6-Mont...Khaled Ali Ghanayem
Effect of Continuous Infusion of Hypertonic Saline vs Standard Care on 6-Month Neurological Outcomes in Patients With Traumatic Brain Injury The COBI Randomized Clinical Trial - Journal club.
JAMA. 2021;325(20):2056-2066. doi:10.1001/jama.2021.5561
This document discusses prehospital stroke care. It notes that time is critical, as brain cells die every minute after a stroke occurs, increasing the risk of permanent damage. Key strategies to reduce treatment time include emergency medical service pre-notification, activating a stroke team with a single call, rapid brain imaging, and acute stroke management protocols. Guidelines for prehospital stroke systems recommend fast symptom recognition, determining the hospital destination before transport, and using telemedicine to help identify appropriate treatments and notify hospitals. The future of prehospital stroke care could see more use of technologies like tele-stroke and stroke emergency mobile units to further reduce time to treatment.
Pharmacological management of cerebral vasospasm in subarachnoid hemorrhagePrisma Health Upstate
Medical management of vasospasm in subarachnoid hemorrhage patients. Despite targeting multiple pathophysiological mechanisms of DCI and vasospasm, most of the trials did not yield results that could translate to clinical practice. Fasudil and emerging therapies like cisternal irrigation and lumbar drainage combined with intrathecal vasodilators and phosphodiesterase medications showed promising results but need to be tested in a randomized clinical trial for effectiveness.
Presentation from the UK NSC conference in December 2016 about the recommendation on the use of pulse oximetry screening for critical congenital heart disease in newborns.
This document summarizes a presentation about the UK National Screening Committee (UK NSC). It discusses the committee's role in advising on screening programs, challenges like ensuring evidence-based decisions and effective communication, and the vision for continuing to provide high-quality independent advice on screening to maximize benefits and minimize harms. Key areas covered include screening criteria, evidence review processes, stakeholder engagement, and evaluating existing and new screening proposals.
Screening for critical_congenital_heart_defects_with_pulse_oximetry_uk_perspe...eram sid
This document discusses pulse oximetry screening for critical congenital heart defects. It provides background on studies showing pulse oximetry can detect many cases of critical CHD before clinical symptoms appear. While early studies had small sample sizes, later studies of over 100,000 babies screened in the UK found a sensitivity of 83.6% and low false positive rate of 0.3%. The document examines different screening protocols and their effectiveness. It concludes that pulse oximetry screening is a feasible, acceptable, and cost-effective approach to reducing the diagnostic gap for critical CHD.
Effect of Continuous Infusion of Hypertonic Saline vs Standard Care on 6-Mont...Khaled Ali Ghanayem
Effect of Continuous Infusion of Hypertonic Saline vs Standard Care on 6-Month Neurological Outcomes in Patients With Traumatic Brain Injury The COBI Randomized Clinical Trial - Journal club.
JAMA. 2021;325(20):2056-2066. doi:10.1001/jama.2021.5561
This document discusses prehospital stroke care. It notes that time is critical, as brain cells die every minute after a stroke occurs, increasing the risk of permanent damage. Key strategies to reduce treatment time include emergency medical service pre-notification, activating a stroke team with a single call, rapid brain imaging, and acute stroke management protocols. Guidelines for prehospital stroke systems recommend fast symptom recognition, determining the hospital destination before transport, and using telemedicine to help identify appropriate treatments and notify hospitals. The future of prehospital stroke care could see more use of technologies like tele-stroke and stroke emergency mobile units to further reduce time to treatment.
Pharmacological management of cerebral vasospasm in subarachnoid hemorrhagePrisma Health Upstate
Medical management of vasospasm in subarachnoid hemorrhage patients. Despite targeting multiple pathophysiological mechanisms of DCI and vasospasm, most of the trials did not yield results that could translate to clinical practice. Fasudil and emerging therapies like cisternal irrigation and lumbar drainage combined with intrathecal vasodilators and phosphodiesterase medications showed promising results but need to be tested in a randomized clinical trial for effectiveness.
An analysis of outcomes of emergency physicianDrArpan Chouhan
This study analyzed outcomes of emergency department-based thrombolysis for stroke performed at Scarborough Acute Trust in the UK between 2004-2009. 110 patients received thrombolysis for acute ischemic stroke. 79 patients treated through the emergency department had an average treatment time of 2.7 hours and 6-month mortality of 15%. 19 patients treated from hospital wards had a treatment time of 3.4 hours and 12% mortality. Outcomes were similar to other European cohorts. The study concluded that thrombolysis for acute ischemic stroke is achievable and safe in district general hospital settings.
Pesit trial New England Journal of MedicineDr fakhir Raza
first episode of syncope, should we do workup for Pulmonary embolism well simplified criteria D dimer level CT angiogram ventilation perfusion scanning
This study aimed to determine the prevalence of pulmonary embolism (PE) in patients hospitalized for a first episode of syncope. The study enrolled 560 consecutive patients from 11 Italian hospitals who were admitted for syncope. PE was confirmed in 97 of the 560 patients using D-dimer testing, modified Wells criteria, and CT pulmonary angiography or VQ scanning. This represents a prevalence of PE of 17.3% among patients hospitalized for first-time syncope. Over 60% of confirmed PEs involved the main pulmonary artery or lobar arteries. While the study identified a non-negligible prevalence of PE in syncopatic patients, it did not determine whether the identified PEs caused the syncope episodes
1. The document discusses a convergent approach for treating persistent atrial fibrillation that combines minimally invasive percutaneous endocardial ablation with epicardial ablation via a closed chest, trans-diaphragmatic endoscopic approach.
2. It has shown success rates of 79-89% at 6-12 months for controlling persistent AF with this multi-disciplinary approach.
3. The approach aims to improve outcomes over percutaneous ablation alone, which has lower success rates for persistent AF and often requires multiple repeat procedures.
Introduction: Recent times have witnessed almost half, or sometimes more cardiac surgical procedures are performed in patients above 75 years of age. Traditionally, the EuroSCORE II and STS risk scoring systems have been widely used across the globe. Extensive reviews have shown that EuroSCORE II probably overestimates the perioperative risk at lower score levels while the STS score tends to underestimate the risk.
Frailty is a broad term that encircles aspects of nutrition, lack of agility, inactivity, lack of strength and wasting; and is seen in 25-50% of elderly patients. It has been defined as a geriatric syndrome reflecting a state of reduced physiological reserve and increased vulnerability to poor resolution of homeostasis after a stressor event. Conversely, pre-frailty, which is potentially reversible, is associated with higher risk of older adults developing cardiovascular disease.
Frailty assessment includes a variety of physical and cognitive tests, functional assessments and evaluating nutritional status. Literature has highlighted what is referred to as the ‘obesity paradox’, meaning obese patients with heart failure fair better than leaner patients, possibly because they have more metabolic reserve and also because weight loss in itself is a risk factor for frailty.
Patient Selection: To comprehensively assess a patient, factors that describe the biological status of the patient should be incorporated. There are various methods of assessment and modified Fried criteria or comprehensive assessment of frailty are a couple of systems commonly used.
Conclusion: Systematic reviews have shown that frail patients have higher chance of mortality, major adverse cardiac and cerebrovascular events and functional decline after cardiac surgery. A holistic assessment not only categorises patients into the apt risk category and hence match goals and treatments; but also, will pick up patients with pre-frailty who will benefit from multidisciplinary intervention and be better prepared for the intervention.
Actigraphy as a Metric in PAH Research and Clinical CareDuke Heart
Actigraphy devices can provide objective measures of physical activity and are being used more in PAH research and clinical care. Limitations of the 6-minute walk test include only providing a snapshot of function and not capturing daily fluctuations. Activity monitors continuously measure real-world activity levels and have been used in clinical trials to assess changes from baseline as primary or secondary endpoints. Emerging data suggest PAH patients have significantly reduced activity levels compared to controls and activity levels correlate with functional class and quality of life. Activity monitors may help evaluate therapeutic responses more sensitively than the 6-minute walk test alone.
This randomized clinical trial compared the effects of 20% mannitol versus 3% hypertonic saline on controlling intracranial pressure in children with raised ICP due to acute CNS infection. The study found that 3% hypertonic saline was more effective at achieving the target ICP < 20 mmHg within 72 hours and resulted in better neurological outcomes, shorter duration of mechanical ventilation and PICU stay, and less severe disability compared to 20% mannitol. While hypernatremia was more common with hypertonic saline, both treatments had a similar safety profile otherwise. The study demonstrated that 3% hypertonic saline is superior to 20% mannitol for managing raised ICP in pediatric CNS
Let's Talk Research 2015 - James Ritchie - Improving care and physician educa...NHSNWRD
This document discusses acute kidney injury (AKI) and describes an AKI Care app being developed to improve physician education and patient care for AKI. The app aims to help assess AKI risk factors, recognize AKI, treat complications, and determine if renal referral is needed. It calculates AKI stage and provides treatment advice. Early user data shows it is being used mostly by junior doctors to assess AKI and its complications, and 60% of users interact with the app's treatment guidance. Further development will focus on integrating it directly into local clinical systems and identifying opportunities for testing with real patients.
This document discusses using a combination of the ICH (Intracerebral Hemorrhage) score and Graeb score to improve prediction of outcomes in patients with spontaneous intracerebral hemorrhage. The ICH score uses factors like initial hemorrhage volume and Glasgow Coma Scale score, while the Graeb score estimates blood in the ventricles from CT scans. A study of 88 patients found that using both scores together produced higher sensitivity, specificity and accuracy in predicting unfavorable outcomes than either score alone. The combination score may be useful as a screening tool to help determine prognosis and guide management decisions for patients with ICH.
The document discusses Modified Early Obstetric Warning Scores (MEOWS), which were introduced in the UK to decrease maternal mortality by improving early detection of clinical deterioration in pregnant women. MEOWS involves routinely monitoring and recording vital signs and assigning a score based on abnormalities, with higher scores triggering more urgent review. It is a standardized screening tool used to assist in early recognition of physiological signs of deterioration and intervention for at-risk pregnant women. Regular MEOWS assessments performed by trained midwives can help identify issues earlier before signs worsen and improve outcomes.
Joint Symposium of the Heart Failure Society of America and the American Coll...drucsamal
1) Approximately half of patients with acute decompensated heart failure (ADHF) develop hemoconcentration (HC), or an increase in blood solutes like hemoglobin and proteins, during diuretic treatment for decongestion.
2) Several retrospective studies have found that patients who develop HC have better clinical outcomes, likely due to achieving better decongestion, however the data does not support using HC routinely in ADHF management.
3) There are many outstanding questions about how to define and measure HC best, and at what level and timing it should be achieved to guide decongestion therapy. Prospective studies are still needed to determine if HC can help guide decongestion treatment.
This document discusses risk stratification tools for sudden cardiac death (SCD). It describes several markers that can help identify patients at high risk, including depressed left ventricular ejection fraction, non-sustained ventricular tachycardia, frequent ventricular ectopy, prolonged QRS duration, T-wave alternans, electrophysiology studies, signal-averaged electrocardiography, QT dispersion, and markers of abnormal autonomic balance like reduced heart rate variability. While no single tool is perfect, combining several markers can improve prediction of SCD risk compared to relying on any one marker alone.
This document summarizes a retrospective study of patients with brain tumors treated between 2006-2014. The study aimed to determine the incidence of hyponatremia during treatment and characterize management approaches. The results showed that 29% of patients developed hyponatremia, with 35% having clinically significant hyponatremia requiring treatment. Diagnosis and treatment of hyponatremia lacked standardization. The conclusions indicate hyponatremia is a common complication in brain tumor patients but can be improved by standardizing diagnosis and management.
American Stroke Association recommendations on Ischemic stroke with edema.Irfaan Shah
This document from the American Heart Association provides recommendations for managing cerebral or cerebellar infarction with swelling. It defines terms like malignant middle cerebral artery infarction and outlines the epidemiology, clinical presentation, neuroimaging findings, triage considerations, and recommendations for airway management, mechanical ventilation, and hemodynamic support of patients experiencing brain swelling after an ischemic stroke. Standardized definitions and further data collection are needed to help guide treatment of this complication.
A pilot study to investigate the feasibility and acceptability of Telehealth ...3GDR
Dr Kenneth Law, MBChB MRCGP MSc Health Informatics, GP and Clinical Lead of Innovation Local Care Direct, University of Leeds.
https://mhealthinsight.com/2016/06/27/join-us-at-the-kings-funds-digital-health-care-congress/
Early warning scores (EWS) are used to facilitate early detection of patient deterioration. The EWS system assigns points to physiological parameters like respiration, oxygen saturation, blood pressure, and temperature to determine a total score. This score dictates the frequency of monitoring and urgency of clinical review. Higher scores indicate more frequent monitoring and quicker medical review are needed. The system aims to standardize recognition of worsening conditions and ensure prompt treatment. Case studies are presented to demonstrate how EWS would be applied in clinical practice.
This document discusses cerebral gas embolism, including two case studies. It covers the etiology, pathophysiology, clinical features, management, and prognosis of both arterial and venous gas embolism. Arterial embolism can result from direct gas entry into arteries or paradoxical embolism through a PFO. Venous embolism occurs when bubbles retrogradely ascend veins and enter the cerebral venous system. Clinical features include neurological deficits. Management involves laying the patient flat, hyperbaric oxygen therapy, and treating complications. Prognosis depends on factors like volume of air and speed of accumulation, with earlier treatment leading to better outcomes.
The greatest pleasure in life is doing what people say you cannot do. Anonymo...NHS Improving Quality
The document discusses issues with diagnosing and managing patients with respiratory conditions like COPD, asthma, and heart failure in primary care settings, noting evidence of high rates of misdiagnosis, underdiagnosis of comorbidities, and fragmented services. It proposes a new enhanced care/case management service called the "Breathlessness Service" to provide more coordinated care to improve outcomes for these patients experiencing breathlessness. Case studies are presented showing how the new service achieved better diagnoses and management of patients' conditions.
Public Health England hosts the UK National Screening Committee, which annually calls for proposals for new screening topics. Anyone can submit a proposal using a template form by January 9th. Successful proposals are externally assessed based on the supporting evidence provided. Proposals that merit further investigation based on available evidence may be selected to undergo more in-depth review through the normal screening committee process. The goal is to provide transparency around how new screening topics are proposed and selected in the UK.
An analysis of outcomes of emergency physicianDrArpan Chouhan
This study analyzed outcomes of emergency department-based thrombolysis for stroke performed at Scarborough Acute Trust in the UK between 2004-2009. 110 patients received thrombolysis for acute ischemic stroke. 79 patients treated through the emergency department had an average treatment time of 2.7 hours and 6-month mortality of 15%. 19 patients treated from hospital wards had a treatment time of 3.4 hours and 12% mortality. Outcomes were similar to other European cohorts. The study concluded that thrombolysis for acute ischemic stroke is achievable and safe in district general hospital settings.
Pesit trial New England Journal of MedicineDr fakhir Raza
first episode of syncope, should we do workup for Pulmonary embolism well simplified criteria D dimer level CT angiogram ventilation perfusion scanning
This study aimed to determine the prevalence of pulmonary embolism (PE) in patients hospitalized for a first episode of syncope. The study enrolled 560 consecutive patients from 11 Italian hospitals who were admitted for syncope. PE was confirmed in 97 of the 560 patients using D-dimer testing, modified Wells criteria, and CT pulmonary angiography or VQ scanning. This represents a prevalence of PE of 17.3% among patients hospitalized for first-time syncope. Over 60% of confirmed PEs involved the main pulmonary artery or lobar arteries. While the study identified a non-negligible prevalence of PE in syncopatic patients, it did not determine whether the identified PEs caused the syncope episodes
1. The document discusses a convergent approach for treating persistent atrial fibrillation that combines minimally invasive percutaneous endocardial ablation with epicardial ablation via a closed chest, trans-diaphragmatic endoscopic approach.
2. It has shown success rates of 79-89% at 6-12 months for controlling persistent AF with this multi-disciplinary approach.
3. The approach aims to improve outcomes over percutaneous ablation alone, which has lower success rates for persistent AF and often requires multiple repeat procedures.
Introduction: Recent times have witnessed almost half, or sometimes more cardiac surgical procedures are performed in patients above 75 years of age. Traditionally, the EuroSCORE II and STS risk scoring systems have been widely used across the globe. Extensive reviews have shown that EuroSCORE II probably overestimates the perioperative risk at lower score levels while the STS score tends to underestimate the risk.
Frailty is a broad term that encircles aspects of nutrition, lack of agility, inactivity, lack of strength and wasting; and is seen in 25-50% of elderly patients. It has been defined as a geriatric syndrome reflecting a state of reduced physiological reserve and increased vulnerability to poor resolution of homeostasis after a stressor event. Conversely, pre-frailty, which is potentially reversible, is associated with higher risk of older adults developing cardiovascular disease.
Frailty assessment includes a variety of physical and cognitive tests, functional assessments and evaluating nutritional status. Literature has highlighted what is referred to as the ‘obesity paradox’, meaning obese patients with heart failure fair better than leaner patients, possibly because they have more metabolic reserve and also because weight loss in itself is a risk factor for frailty.
Patient Selection: To comprehensively assess a patient, factors that describe the biological status of the patient should be incorporated. There are various methods of assessment and modified Fried criteria or comprehensive assessment of frailty are a couple of systems commonly used.
Conclusion: Systematic reviews have shown that frail patients have higher chance of mortality, major adverse cardiac and cerebrovascular events and functional decline after cardiac surgery. A holistic assessment not only categorises patients into the apt risk category and hence match goals and treatments; but also, will pick up patients with pre-frailty who will benefit from multidisciplinary intervention and be better prepared for the intervention.
Actigraphy as a Metric in PAH Research and Clinical CareDuke Heart
Actigraphy devices can provide objective measures of physical activity and are being used more in PAH research and clinical care. Limitations of the 6-minute walk test include only providing a snapshot of function and not capturing daily fluctuations. Activity monitors continuously measure real-world activity levels and have been used in clinical trials to assess changes from baseline as primary or secondary endpoints. Emerging data suggest PAH patients have significantly reduced activity levels compared to controls and activity levels correlate with functional class and quality of life. Activity monitors may help evaluate therapeutic responses more sensitively than the 6-minute walk test alone.
This randomized clinical trial compared the effects of 20% mannitol versus 3% hypertonic saline on controlling intracranial pressure in children with raised ICP due to acute CNS infection. The study found that 3% hypertonic saline was more effective at achieving the target ICP < 20 mmHg within 72 hours and resulted in better neurological outcomes, shorter duration of mechanical ventilation and PICU stay, and less severe disability compared to 20% mannitol. While hypernatremia was more common with hypertonic saline, both treatments had a similar safety profile otherwise. The study demonstrated that 3% hypertonic saline is superior to 20% mannitol for managing raised ICP in pediatric CNS
Let's Talk Research 2015 - James Ritchie - Improving care and physician educa...NHSNWRD
This document discusses acute kidney injury (AKI) and describes an AKI Care app being developed to improve physician education and patient care for AKI. The app aims to help assess AKI risk factors, recognize AKI, treat complications, and determine if renal referral is needed. It calculates AKI stage and provides treatment advice. Early user data shows it is being used mostly by junior doctors to assess AKI and its complications, and 60% of users interact with the app's treatment guidance. Further development will focus on integrating it directly into local clinical systems and identifying opportunities for testing with real patients.
This document discusses using a combination of the ICH (Intracerebral Hemorrhage) score and Graeb score to improve prediction of outcomes in patients with spontaneous intracerebral hemorrhage. The ICH score uses factors like initial hemorrhage volume and Glasgow Coma Scale score, while the Graeb score estimates blood in the ventricles from CT scans. A study of 88 patients found that using both scores together produced higher sensitivity, specificity and accuracy in predicting unfavorable outcomes than either score alone. The combination score may be useful as a screening tool to help determine prognosis and guide management decisions for patients with ICH.
The document discusses Modified Early Obstetric Warning Scores (MEOWS), which were introduced in the UK to decrease maternal mortality by improving early detection of clinical deterioration in pregnant women. MEOWS involves routinely monitoring and recording vital signs and assigning a score based on abnormalities, with higher scores triggering more urgent review. It is a standardized screening tool used to assist in early recognition of physiological signs of deterioration and intervention for at-risk pregnant women. Regular MEOWS assessments performed by trained midwives can help identify issues earlier before signs worsen and improve outcomes.
Joint Symposium of the Heart Failure Society of America and the American Coll...drucsamal
1) Approximately half of patients with acute decompensated heart failure (ADHF) develop hemoconcentration (HC), or an increase in blood solutes like hemoglobin and proteins, during diuretic treatment for decongestion.
2) Several retrospective studies have found that patients who develop HC have better clinical outcomes, likely due to achieving better decongestion, however the data does not support using HC routinely in ADHF management.
3) There are many outstanding questions about how to define and measure HC best, and at what level and timing it should be achieved to guide decongestion therapy. Prospective studies are still needed to determine if HC can help guide decongestion treatment.
This document discusses risk stratification tools for sudden cardiac death (SCD). It describes several markers that can help identify patients at high risk, including depressed left ventricular ejection fraction, non-sustained ventricular tachycardia, frequent ventricular ectopy, prolonged QRS duration, T-wave alternans, electrophysiology studies, signal-averaged electrocardiography, QT dispersion, and markers of abnormal autonomic balance like reduced heart rate variability. While no single tool is perfect, combining several markers can improve prediction of SCD risk compared to relying on any one marker alone.
This document summarizes a retrospective study of patients with brain tumors treated between 2006-2014. The study aimed to determine the incidence of hyponatremia during treatment and characterize management approaches. The results showed that 29% of patients developed hyponatremia, with 35% having clinically significant hyponatremia requiring treatment. Diagnosis and treatment of hyponatremia lacked standardization. The conclusions indicate hyponatremia is a common complication in brain tumor patients but can be improved by standardizing diagnosis and management.
American Stroke Association recommendations on Ischemic stroke with edema.Irfaan Shah
This document from the American Heart Association provides recommendations for managing cerebral or cerebellar infarction with swelling. It defines terms like malignant middle cerebral artery infarction and outlines the epidemiology, clinical presentation, neuroimaging findings, triage considerations, and recommendations for airway management, mechanical ventilation, and hemodynamic support of patients experiencing brain swelling after an ischemic stroke. Standardized definitions and further data collection are needed to help guide treatment of this complication.
A pilot study to investigate the feasibility and acceptability of Telehealth ...3GDR
Dr Kenneth Law, MBChB MRCGP MSc Health Informatics, GP and Clinical Lead of Innovation Local Care Direct, University of Leeds.
https://mhealthinsight.com/2016/06/27/join-us-at-the-kings-funds-digital-health-care-congress/
Early warning scores (EWS) are used to facilitate early detection of patient deterioration. The EWS system assigns points to physiological parameters like respiration, oxygen saturation, blood pressure, and temperature to determine a total score. This score dictates the frequency of monitoring and urgency of clinical review. Higher scores indicate more frequent monitoring and quicker medical review are needed. The system aims to standardize recognition of worsening conditions and ensure prompt treatment. Case studies are presented to demonstrate how EWS would be applied in clinical practice.
This document discusses cerebral gas embolism, including two case studies. It covers the etiology, pathophysiology, clinical features, management, and prognosis of both arterial and venous gas embolism. Arterial embolism can result from direct gas entry into arteries or paradoxical embolism through a PFO. Venous embolism occurs when bubbles retrogradely ascend veins and enter the cerebral venous system. Clinical features include neurological deficits. Management involves laying the patient flat, hyperbaric oxygen therapy, and treating complications. Prognosis depends on factors like volume of air and speed of accumulation, with earlier treatment leading to better outcomes.
The greatest pleasure in life is doing what people say you cannot do. Anonymo...NHS Improving Quality
The document discusses issues with diagnosing and managing patients with respiratory conditions like COPD, asthma, and heart failure in primary care settings, noting evidence of high rates of misdiagnosis, underdiagnosis of comorbidities, and fragmented services. It proposes a new enhanced care/case management service called the "Breathlessness Service" to provide more coordinated care to improve outcomes for these patients experiencing breathlessness. Case studies are presented showing how the new service achieved better diagnoses and management of patients' conditions.
Public Health England hosts the UK National Screening Committee, which annually calls for proposals for new screening topics. Anyone can submit a proposal using a template form by January 9th. Successful proposals are externally assessed based on the supporting evidence provided. Proposals that merit further investigation based on available evidence may be selected to undergo more in-depth review through the normal screening committee process. The goal is to provide transparency around how new screening topics are proposed and selected in the UK.
Pulse Oximetry Screening for Detecting Critical Congenital Heart Diseasejrhoffmann
Critical Congenital Heart Disease (CCHD) screening involves performing pulse oximetry tests on newborns prior to discharge from the hospital to detect heart defects. Without screening, approximately 170 babies per year were discharged with undetected CCHD. Screening costs an estimated $14-36 per baby. Many states have passed laws requiring CCHD screening in hospitals and over 90% of Kansas babies are currently screened. Resources for training and consultation on screening are available.
The Power of Pulse Oximetry to Identify Babies with Congenital Heart Defects:...Leith Greenslade
This document lists 7 primary congenital heart defects, describes a meta-analysis of 13 studies using pulse oximetry screening on over 229,000 newborns to detect critical congenital heart defects, and found an overall sensitivity of 76.5%, specificity of 99.9%, and low false positive rate of 0.14% when screening was performed after 24 hours of birth.
Sudden cardiac arrest/death is the sudden cessation of cardiac activity that can lead to death if not treated rapidly. It is usually due to sustained ventricular tachycardia or fibrillation. Ischemic heart disease is the leading cause, accounting for around 70% of cases. Risk increases with age and underlying cardiac conditions. While screening the general population has not been shown to effectively identify high risk individuals, risk factor reduction through treatments like controlling hypertension, cholesterol, and diabetes as well as lifestyle changes can help with primary prevention. For secondary prevention, an implantable cardioverter-defibrillator is the preferred treatment for survivors of sudden cardiac arrest to terminate recurrent ventricular arrhythmias.
update on sudden cardiac death in athletes and young generationTamer Taha
This document discusses updates on sudden cardiac death in athletes and young people. It begins by outlining the benefits of exercise but notes there are also small risks, particularly for those with underlying heart conditions. For young athletes, the main causes of sudden cardiac death are structural heart diseases like hypertrophic cardiomyopathy, channelopathies (genetic arrhythmia conditions), and myocarditis. Screening aims to identify at-risk individuals to prevent lethal events. In adult athletes, coronary artery disease is the primary cause of death, and risk factors like genetics, inflammation and vascular factors can increase likelihood of issues.
This document provides an overview of syncope (transient loss of consciousness). It discusses the pathophysiology, typical presentations, differential diagnoses, evaluation and treatment of different syncope types. The main causes discussed are neurally-mediated syncope (the most common), orthostatic hypotension, and cardiac syncope. For evaluation, the document recommends a thorough history, physical exam including orthostatic vital signs and carotid sinus massage in older patients, and tests like ECG, tilt table testing and cardiac monitoring. Treatment depends on the underlying cause, including fluid supplementation, compression stockings and pharmacotherapy for orthostatic hypotension, and pacing for cardiac syncope.
The Long QT Syndrome: Overview and Management The Long QT Syndrome: Overvie...MedicineAndFamily
Long QT Syndrome is a genetic disorder characterized by a prolonged QT interval on electrocardiogram that can cause dangerous arrhythmias and sudden cardiac death. Symptoms include unexplained fainting, seizures, or sudden death, especially with exercise or emotions. Treatment involves beta blockers, implantable cardioverter defibrillators, or left stellate ganglionectomy depending on risk level and genotype. Ongoing research seeks to better understand genotype-phenotype relationships and develop mutation-specific therapies.
Syncope is defined as a transient loss of consciousness due to decreased cerebral blood flow. It is commonly caused by neurally-mediated reflexes, orthostatic hypotension, or cardiac arrhythmias. Evaluation involves determining the cause through history, physical exam, ECG and tests like tilt table testing, echocardiogram, and cardiac monitoring. Treatment depends on the underlying cause and may include lifestyle changes, medications, pacemakers, or defibrillators.
This document discusses sudden cardiac arrest (SCA) and sudden cardiac death (SCD). SCA refers to sudden cessation of cardiac activity that may be reversible by interventions like defibrillation, while SCD is uncorrected SCA that leads to death. SCD is defined as natural death from cardiac causes within one hour of symptoms in someone who may have unrecognized heart disease. About 500,000 cases occur annually in the US, accounting for 10-15% of natural deaths. Risk factors include prior arrhythmias, low ejection fraction, heart disease, and family history. Treatment involves cardiopulmonary resuscitation, defibrillation if needed, and treating underlying causes. Advanced cardiac life support may include int
Globally, about 17 million strokes occur every year. Stroke is the second leading cause of death and the third most common cause of disability worldwide. The presentation of stroke includes sudden onset of focal neurological deficits such as numbness, weakness, confusion, trouble speaking or understanding, or trouble with vision, walking, balance or coordination. Timely treatment is critical, as more time elapsed means greater brain damage. Prehospital evaluation involves using stroke scales to identify high-risk patients who require rapid transport to certified stroke centers for emergency evaluation and treatment within strict time windows in order to minimize disability or death from stroke.
Improving the Physical health care of people with mental ill health: Cardiovascular health of people with serious mental illness National Learning Network Event 29th April 2015.
Main Slide: NHS IQ CVD SMI LNE 29 April 2015 slides - 1-152
BREAKOUT 1_PATIENT VOICE slides 153-161
BREAKOUT 2a_IMPROVING CARDIOVASCULAR CARE FOR PEOPLE WITH SMI - slides 162-188
BREAKOUT 2b_UCLP PROGRAMME ON CVDSMI - slides 188-195
BREAKOUT 3_PHYSICAL ACTIVITY IN MENTAL HEALTH - slides 196-212
BREAKOUT 4_REASONS FOR TEWVS SUCCESS - slides 213-225
BREAKOUT 5_ PHYSICAL HEALTH AND WELLBEING - slides 226-243
BREAKOUT 6_SHAPE - slides 244-271
BREAKOUT 7_SCREENING FOR CARDIOMETABOLIC RISK FACTORS - slides 272 -296
The DANISH trial investigated whether implantable cardioverter-defibrillators (ICDs) improve outcomes for patients with non-ischemic cardiomyopathy (NICMP) receiving optimal medical therapy including cardiac resynchronization therapy (CRT) when needed. The trial found that ICDs did not provide an overall survival benefit but did halve the risk of sudden cardiac death, with younger patients experiencing mortality benefit from ICDs. The results have led some clinicians to consider CRT without defibrillation first for NICMP patients and to more carefully select those who may benefit from ICDs based on age and risk factors. Ongoing research aims to identify better markers beyond ejection fraction to predict arrhythmic risk
ECO 12 - Improving the quality of physical health checksInnovation Agency
Patients with Severe Mental Illness (SMI) experience health inequalities.
The most notable is a shorter lifespan, reduced by around 20 years compared to the general population
There is considerable evidence that one of the main causes of early death in people with SMI is cardiovascular disease
Other physical causes include cancer
This document summarizes a study on deaths related to haemoglobinopathies in the UK from 2005-2006. It reviewed 47 cases and aimed to identify remediable factors in patient care. Key findings included a lack of understanding about sickle cell trait, inconsistent vaccination records, irregular outpatient attendance, and issues with both ongoing and acute pain management including opioid overdoses. Causes of death included stroke, acute chest syndrome, and renal failure, where timely recognition and management could have made a difference. The study made recommendations around improving protocols, guidelines, multi-disciplinary care, and clinician education about haemoglobinopathies.
Case Presentation On Cerebrovascular Accident With Ischemic StrokeDR. METI.BHARATH KUMAR
The document presents a case report of a 47-year-old male patient admitted with weakness on the left side of his body, slurred speech, and nasal regurgitation. Imaging and labs confirmed an ischemic stroke in the right side of the brain. The patient's medical history includes diabetes and hypertension. Treatment included medications to reduce blood pressure and cholesterol, prevent infections, reduce acidity, thin blood, and aid recovery from stroke.
Design and Conduct of Clinical Trials 2016Meguid Nahas
This document provides an overview of how to design, conduct, and report a clinical trial based on a presentation from Prof Meguid El Nahas at the Sheffield Kidney Institute. It discusses ethical considerations like the Declaration of Helsinki, trial design elements like objectives and endpoints, conducting trials according to good clinical practice, statistical analysis, interpreting and reporting results, and how to appraise clinical trials based on factors like validity of results and risk-benefit analysis. The overall document offers guidance on the end-to-end process for clinical research.
Phase III Randomized Controlled Trial to Compare the Efficacy and safety of P...Basim Ibrahim
This document summarizes a clinical trial that aims to compare the efficacy and safety of pitavastatin 4 mg once daily versus simvastatin 40 mg once daily in reducing LDL-C concentrations over 12 weeks in patients with primary hypercholesterolemia or combined dyslipidemia. The trial plans to enroll 355 patients across 15 centers in Canada in a randomized, double-blind, controlled trial. The primary endpoint is the percentage change in LDL-C concentrations from baseline to 12 weeks. Secondary endpoints include changes in other lipid variables. The trial procedures, inclusion/exclusion criteria, and safety and efficacy monitoring plans are described.
Effect of restrictive versus liberal transfusion strategies on outcomes in pa...Mohd Saif Khan
Restrictive red cell transfusion policies are recommended as safe for most hospital patients with anaemia. Uncertainty exists for patients with cardiovascular disease, whose hearts may be more susceptible to limited coronary oxygen supply.
Physical monitoring in Mental Illness - Dr Sadgun BhandariDr Sadgun Bhandari
Physical monitoring in Mental Illness - Dr Sadgun Bhandari is a recognized member of the Royal College of Psychiatrists, UK and also a Fellow of the Royal College of Psychiatrists, UK.
Your heart matters by Dr. Justina Trottsantaferotary
1) Heart disease is the leading cause of death for American women, killing 1 in 3, but risk factors and symptoms can differ between women and men.
2) A new study found that race, gender, and insurance status affect how patients with chest pain are evaluated in emergency rooms.
3) While heart disease risk rises for women after menopause due to dropping estrogen levels, lifestyle changes like not smoking, managing blood pressure and cholesterol, and regular exercise can help prevent and control heart disease.
This document provides information about chronic kidney disease (CKD) education programs. It discusses the importance of educating patients early in the stages of CKD to empower them, delay disease progression, and improve outcomes. A community-based CKD education program is described that uses a multidisciplinary team to provide stage-specific education and tools to help patients better manage their health. The goals of CKD education are to help patients understand their kidney function and disease stage, make informed treatment decisions, and preserve renal function through lifestyle changes.
Effects of ivabradine in patients with stable coronary artery disease without clinical heart failure. A randomised double-blind placebo-controlled international multicentre study. Study assessing the morbi-mortality benefits of the If inhibitor ivabradine in patients with coronary artery disease ( SIGNIFY)
Managing Stroke risk in Atrial Fibrillation: Are we fulfilling our potential?
Presented by Mel Varvel - NHS Improving Quality and Marion Kerr - Insight Health Economics at National Association of Primary Care ‘Best Practice’ Conference in Birmingham, October 2013
GRASP-AF tool: Identifies patients with a history of atrial fibrillation
Searches for co-morbidities and calculates a CHADS2 (and now CHA2DS2-VASc) score
Searches for current medication- warfarin, aspirin or newer oral anticoagulant
Searches for recorded reasons for NOT treating with OAC
Gives a simple alert for those at high risk and not on warfarin or newer oral anticoagulant
Revolutionizing Renal Care With Predictive Analytics for CKDViewics
Chronic Kidney Disease (CKD) is a common and growing condition, affecting about half of the Medicare population and of diabetics. In the United States, the lifetime risk of CKD for 30-year-olds is now greater than half, and the prevalence of CKD is projected to rise significantly over the next 15 years.
Current methods of predicting which CKD patients will progress to renal failure and require dialysis or transplant have low accuracy rates, causing great anxiety and suboptimal care. Without accurate risk prediction, many patients are over-treated, effectively wasting limited resources and negatively impacting outcomes. Conversely, other patients may receive inadequate treatment, restricting options to only the most costly and least desirable interventions.
Watch this on-demand webinar with Dr. Navdeep Tangri, developer of the Kidney Failure Risk Equation, which revolutionizes the way CKD patients are managed by leveraging laboratory data to accurately predict the risk of kidney failure in patients with CKD.
You’ll learn:
• How CKD is burdening our healthcare system, and the need for better care management tools
• How the Kidney Failure Risk Equation was researched, developed, and validated
• How Viewics is implementing CKD predictive analytics to automatically deliver risk information to clinicians and issue customized, educational reports to patients and clinicians
CT Scanning For First Time Seizures At UHWI Clincal policy audit Group 3 dr b...Dr. Peter Andre Soltau
This document describes a clinical audit of the management of first time seizures presented to the emergency department of a tertiary hospital in Jamaica. The objectives were to evaluate compliance with the hospital's seizure protocol for performing CT scans and arranging appropriate follow up. Medical records of 133 patients with suspected first time seizures over one year were reviewed, of which 44 met inclusion criteria. The results found high compliance with indications for CT scanning in the ED but poor documentation of seizure duration, follow up instructions, and arranging outpatient CT when indicated. The audit recommendations include improving documentation, staff education on the seizure protocol, and implementing an electronic medical record system.
NHS screening leaflet short urls and qr codes PDFPHEScreening
This document provides short URLs and QR codes for digital information leaflets about various NHS screening programs in the UK, including antenatal and newborn, AAA, bowel cancer, breast cancer, cervical cancer, and diabetic eye screening. Short URLs and QR codes are included to easily direct people to online collections of digital information leaflets for each screening program through mobile devices.
NHS screening leaflet short urls and qr codesPHEScreening
This document provides short URLs and QR codes for digital information leaflets about various NHS screening programs in the UK, including antenatal and newborn, AAA, bowel cancer, breast cancer, cervical cancer, and diabetic eye screening. Short URLs and QR codes are included to easily direct people to online collections of digital information leaflets for each screening program through mobile devices.
PHE screening inequalities conference final slidesPHEScreening
This document outlines plans for a conference on addressing inequalities in screening. The aims of the conference are to share information on actions being taken to tackle inequalities, seek expert input on further steps, and discuss successes and new learning. The document provides background on PHE's screening inequalities strategy, examples of data showing inequalities, and initiatives underway like the FIT screening implementation and health equity audit toolkit. Speakers will discuss evidence-based practices to address inequalities including effective invitee interventions and potential program-level changes. The final section covers accessing screening data to support inequalities work while complying with information governance.
1) The document discusses health inequalities and screening inequalities, noting that uptake rates tend to be lower for those in more deprived socioeconomic groups and for certain minority populations.
2) It provides an overview of the Public Health England's Screening Division Inequalities Strategy, which aims to increase uptake in the most deprived areas by 10% by addressing barriers to screening.
3) The strategy involves tools to help services analyze uptake data and identify groups with lower participation, as well as guidance on improving access for populations such as those with severe mental illness.
The document discusses health inequalities in cancer screening programs. It aims to familiarize screening technicians with health inequalities, update them on initiatives to address inequalities from the UK Public Health England screening division, and explore further actions that could be taken. It notes that screening inequalities exist for groups experiencing economic deprivation, minority ethnic groups, people with disabilities, and other protected groups. Addressing inequalities requires understanding differences in participation within and between screening programs and targeting groups at higher risk who are less likely to participate. Actions discussed include analyzing screening data to identify inequalities, making programs more accessible, and establishing collaboration groups to share information.
1) The document discusses health inequalities in cancer screening programs. It notes that uptake rates tend to be lower for populations experiencing economic deprivation, belonging to minority ethnic groups, or having disabilities.
2) Data is presented showing gaps in life expectancy between deprived and affluent areas of up to 9 years for males. Screening coverage and outcomes also tend to be lower for disadvantaged groups.
3) Actions are proposed to improve accessibility of screening for people with disabilities or severe mental illness through targeted outreach and accommodations. Establishing collaborations through online platforms and sharing work at program board meetings is encouraged.
This document discusses health inequalities and screening inequalities. It aims to refresh knowledge on health inequalities, update on the Public Health England screening division's inequalities strategy, and explore actions screening nurses can take to tackle inequalities. It provides data showing screening uptake disparities based on factors like learning disabilities, ethnicity, and socioeconomic status. It also outlines guidance and tools to help screening services increase uptake in deprived areas and make screening more accessible for groups facing inequalities.
AAA Screening : Extending the screener rolePHEScreening
This document describes extending the role of screening technicians in an abdominal aortic aneurysm (AAA) screening program to include basic physical health checks. It provides details on the current and proposed screening models, including the additional training and guidance technicians receive to take blood pressure and seek nurse advice. An example is given of how a high blood pressure reading was identified during screening and subsequently treated, benefiting both the patient and their GP. Feedback from patients and GPs is positive about the expanded technician role in detecting other health issues alongside AAA screening.
AAA Screening : Extending the screener role for nursesPHEScreening
The document discusses extending the role of screening technicians in an abdominal aortic aneurysm (AAA) screening program to include basic physical health checks. The program saw a decline in eligible men for screening over time as the population grew. The extended screener role would have technicians take basic observations like blood pressure and seek nurse practitioner advice if needed. Patients would receive education materials and follow up calls. Nurses would conduct further assessments over the phone. The changes aim to catch other health issues and assure quality through training, audits, and patient and doctor feedback. The feedback received has been positive.
AAA screening national programme update September 2019: Lisa SummersPHEScreening
This document provides a national update on the AAA screening programme in the UK. It discusses updates to clinical leads, screening figures, key performance indicators, standards and guidance, IT systems, equipment evaluation, rationale for modifying surveillance intervals, and initiatives across the four nations and to address inequalities in screening.
Improving outcomes of patients on AAA surveillance Adam HaquePHEScreening
This document discusses improving outcomes for patients undergoing abdominal aortic aneurysm (AAA) surveillance through exercise interventions. It presents evidence that cardiovascular fitness, as measured by cardiopulmonary exercise testing (CPET), is a key determinant of outcomes for AAA patients. A trial is proposed to evaluate the effects of a 24-week patient-directed exercise program on CPET measures of fitness for AAA surveillance patients compared to standard advice. The goal is to determine if objective measures of cardiovascular fitness can be improved through a scalable and deliverable exercise program to provide benefits like reduced peri-operative risk and improved survival for AAA patients.
AAA nurses training: programme boards presentation September 2019PHEScreening
This document discusses programme boards for screening quality assurance. It notes that nurses rarely attend all programme boards due to small team sizes and priority being given to patient assessments. Programme boards ensure screening programmes meet national standards and involve multiple stakeholder organizations. They discuss performance against quality standards, learning from incidents, and service improvement initiatives. The most discussed topics include performance metrics, incidents and lessons learned, quality assurance visit outcomes, and risks/mitigation plans. Nursing contributions could involve audits on access, uptake, and waiting times. Key messages from boards should be communicated to nursing teams.
AAA screeners LGBT awareness training September 2019PHEScreening
The document discusses LGBTQ+ awareness in abdominal aortic aneurysm screening programs, including definitions of key terms like sexual orientation, gender identity, and pronouns. It also notes potential health inequalities faced by LGBTQ+ people and how current AAA screening procedures and invitations may need improvements to be more inclusive of transgender and non-binary individuals.
Digital screening information event 2 October 2019PHEScreening
Slides from the event for antenatal screening co-ordinators in Birmingham on 2 October 2019 to discuss the plans for moving to digital screening information.
NHS Breast Screening Programme & Association of Breast Surgery AuditPHEScreening
The document describes the NHS Breast Screening Programme (NHSBSP) and Association of Breast Surgery (ABS) audit. The audit compares surgical data to quality assurance standards to assess performance. It analyzes data on all breast cancers detected through screening in the UK each year. The annual audit has three parts - the main audit examines the most recent year's data, the adjuvant audit examines treatment data from the prior year, and the survival audit examines 5-year survival rates. The document provides guidance on extracting data from the NBSS database system, checking the data for errors or missing information, and resolving issues by updating records in NBSS before uploading the data to the Breast Screening System Information System (BSIS
This document provides an update on the Infectious Diseases in Pregnancy Screening (IDPS) Programme in the UK. It discusses the aims of the programme, which include enabling early detection and treatment of infections in pregnancy to reduce mother-to-child transmission. It summarizes screening activity data which shows high uptake rates of over 99% for HIV, hepatitis B, and syphilis screening. It also discusses efforts to improve laboratory quality, establish screening standards and outcomes data, and provide education resources to professionals and the public. Specific updates are provided on actions relating to HIV, syphilis, hepatitis B, and developing seamless maternal and neonatal pathways between screening and immunization programs.
10. Siobhan O'callaghan findings from QA activitiesPHEScreening
The QA advisor summarizes findings from 30 QA visits reports between September 2017 and July 2018. A total of 786 QA recommendations were made across various themes. The top theme was infectious diseases in pregnancy, receiving 218 recommendations. Of these, 61 recommendations were specific to the laboratory, focusing on issues like properly identifying and tracking antenatal samples, notifying screening results, and ensuring UKAS accreditation. Generic recommendations that appeared across themes included formalizing governance, managing incidents, and meeting standards for staff training and turnaround times.
9. Judith Timms HIV screening incidentsPHEScreening
This document discusses false positive HIV results that can occur during HIV screening. The main causes of false positives are wrong blood in the tube or laboratory error. Laboratory error is found to be the most common cause, responsible for false positives in 8 of 9 cases reviewed from 2014 to 2017. Specific cases of laboratory errors are presented, including possible contamination during automated testing processes and issues with old laboratory equipment. The implications of false positive results, such as distress to patients, are also covered.
8. Nadia Permalloo learning from incidentsPHEScreening
This document summarizes themes from quarterly incident reports of a screening program covering October 2015 to December 2017. Key issues identified include screening without informed consent, insufficient samples not being repeated in a timely manner, tracking and communication failures leading to unreported positive screening results, delays when using reference laboratories, and unconfirmed screening results being communicated to patients. The document concludes with a checklist of questions around improving processes to address these issues.
7. Tom Lewis Getting it right for pathology presentationPHEScreening
This document summarizes a presentation on the Getting It Right First Time (GIRFT) program and its workstream focused on pathology. GIRFT aims to reduce unwarranted variation in clinical care through data collection, identifying best practices, and promoting changes. The pathology workstream is led by four clinical leads and aims to measure current variability in pathology services, create a vision for the future, and test changes. Key activities will include collecting data through questionnaires and site visits to understand variations and identify opportunities for improvement.
UN WOD 2024 will take us on a journey of discovery through the ocean's vastness, tapping into the wisdom and expertise of global policy-makers, scientists, managers, thought leaders, and artists to awaken new depths of understanding, compassion, collaboration and commitment for the ocean and all it sustains. The program will expand our perspectives and appreciation for our blue planet, build new foundations for our relationship to the ocean, and ignite a wave of action toward necessary change.
United Nations World Oceans Day 2024; June 8th " Awaken new dephts".Christina Parmionova
The program will expand our perspectives and appreciation for our blue planet, build new foundations for our relationship to the ocean, and ignite a wave of action toward necessary change.
Jennifer Schaus and Associates hosts a complimentary webinar series on The FAR in 2024. Join the webinars on Wednesdays and Fridays at noon, eastern.
Recordings are on YouTube and the company website.
https://www.youtube.com/@jenniferschaus/videos
RFP for Reno's Community Assistance CenterThis Is Reno
Property appraisals completed in May for downtown Reno’s Community Assistance and Triage Centers (CAC) reveal that repairing the buildings to bring them back into service would cost an estimated $10.1 million—nearly four times the amount previously reported by city staff.
Combined Illegal, Unregulated and Unreported (IUU) Vessel List.Christina Parmionova
The best available, up-to-date information on all fishing and related vessels that appear on the illegal, unregulated, and unreported (IUU) fishing vessel lists published by Regional Fisheries Management Organisations (RFMOs) and related organisations. The aim of the site is to improve the effectiveness of the original IUU lists as a tool for a wide variety of stakeholders to better understand and combat illegal fishing and broader fisheries crime.
To date, the following regional organisations maintain or share lists of vessels that have been found to carry out or support IUU fishing within their own or adjacent convention areas and/or species of competence:
Commission for the Conservation of Antarctic Marine Living Resources (CCAMLR)
Commission for the Conservation of Southern Bluefin Tuna (CCSBT)
General Fisheries Commission for the Mediterranean (GFCM)
Inter-American Tropical Tuna Commission (IATTC)
International Commission for the Conservation of Atlantic Tunas (ICCAT)
Indian Ocean Tuna Commission (IOTC)
Northwest Atlantic Fisheries Organisation (NAFO)
North East Atlantic Fisheries Commission (NEAFC)
North Pacific Fisheries Commission (NPFC)
South East Atlantic Fisheries Organisation (SEAFO)
South Pacific Regional Fisheries Management Organisation (SPRFMO)
Southern Indian Ocean Fisheries Agreement (SIOFA)
Western and Central Pacific Fisheries Commission (WCPFC)
The Combined IUU Fishing Vessel List merges all these sources into one list that provides a single reference point to identify whether a vessel is currently IUU listed. Vessels that have been IUU listed in the past and subsequently delisted (for example because of a change in ownership, or because the vessel is no longer in service) are also retained on the site, so that the site contains a full historic record of IUU listed fishing vessels.
Unlike the IUU lists published on individual RFMO websites, which may update vessel details infrequently or not at all, the Combined IUU Fishing Vessel List is kept up to date with the best available information regarding changes to vessel identity, flag state, ownership, location, and operations.
This report explores the significance of border towns and spaces for strengthening responses to young people on the move. In particular it explores the linkages of young people to local service centres with the aim of further developing service, protection, and support strategies for migrant children in border areas across the region. The report is based on a small-scale fieldwork study in the border towns of Chipata and Katete in Zambia conducted in July 2023. Border towns and spaces provide a rich source of information about issues related to the informal or irregular movement of young people across borders, including smuggling and trafficking. They can help build a picture of the nature and scope of the type of movement young migrants undertake and also the forms of protection available to them. Border towns and spaces also provide a lens through which we can better understand the vulnerabilities of young people on the move and, critically, the strategies they use to navigate challenges and access support.
The findings in this report highlight some of the key factors shaping the experiences and vulnerabilities of young people on the move – particularly their proximity to border spaces and how this affects the risks that they face. The report describes strategies that young people on the move employ to remain below the radar of visibility to state and non-state actors due to fear of arrest, detention, and deportation while also trying to keep themselves safe and access support in border towns. These strategies of (in)visibility provide a way to protect themselves yet at the same time also heighten some of the risks young people face as their vulnerabilities are not always recognised by those who could offer support.
In this report we show that the realities and challenges of life and migration in this region and in Zambia need to be better understood for support to be strengthened and tuned to meet the specific needs of young people on the move. This includes understanding the role of state and non-state stakeholders, the impact of laws and policies and, critically, the experiences of the young people themselves. We provide recommendations for immediate action, recommendations for programming to support young people on the move in the two towns that would reduce risk for young people in this area, and recommendations for longer term policy advocacy.
Indira awas yojana housing scheme renamed as PMAYnarinav14
Indira Awas Yojana (IAY) played a significant role in addressing rural housing needs in India. It emerged as a comprehensive program for affordable housing solutions in rural areas, predating the government’s broader focus on mass housing initiatives.
1. Public Health England hosts the UK National Screening Committee
Sudden Cardiac Death
Screening in 12 to 39 year olds
Dr Sunil Bhanot
2. Definition
Sudden Cardiac Death
• Death (unexpected sudden cardiac arrest) occurring within one hour of the
onset of symptoms in a young person without a previously recognised
cardiovascular abnormality
• It is usually precipitated by physical activity
• Causes
• Structural: Hypertrophic Cardiomyopathy
• Electrical abnormalities: Arrhythmia
• External causes: Blunt chest injury
2 Sudden Cardiac Death Screening in 12 to 39 year olds
3. Commissioning
• 2008 UK NSC recommended against Hypertrophic Cardiomyopathy
screening
• Rationale: Accuracy of testing
• High False Positives and False Negatives
• 2013 Present review commissioned
• Undertaken by Phil Wiffen (Oxford Systematic Review Services) and
Mike Clarke (University of Belfast)
• Wider scope exploring broad range of conditions associated with Sudden
Cardiac Death in young people
3 Sudden Cardiac Death Screening in 12 to 39 year olds
4. Document Development
• Literature search
• All research on Sudden Cardiac Death between 1974 and end of 2013
• Primary question
• Impact of screening in reducing incidence of Sudden Cardiac Death in 12
to 39 year olds
• Secondary questions
• Availability of screening tests and their accuracy
• National screening practices
• Evidence of benefits and harms
4 Sudden Cardiac Death Screening in 12 to 39 year olds
5. Review Findings
• Important health issue but uncertainty over incidence
• Poorly understood conditions that lead to Sudden Cardiac Death
• No high quality evidence to guide clinicians advising patients on
management, treatment and lifestyle
• Test performance: No studies reporting on sensitivity and specificity.
• Little screening programme evidence
• Literature mostly on screening in young people participating in sport
• Screening evidence is not peer reviewed or has been questioned
• No direct evidence that screening reduces incidence of Sudden Cardiac
Death
5 Sudden Cardiac Death Screening in 12 to 39 year olds
6. Consultation
• 3 month Consultation opened in November 2014
• Responses from:
• 3 families affected by Sudden Cardiac Death
• Personal submission from National Clinical Director for Heart Disease
• British Cardiovascular Society
• Royal College of Paediatrics and Child Health
• Cardiac Risk in the Young (CRY)
• Consultation responses acknowledged limited evidence around:
• effect of screening on preventing Sudden Cardiac Death
• management of people with risk factors
• Uncertainty of current strategy
• Not all stakeholders agreed with the recommendation
6 Sudden Cardiac Death Screening in 12 to 39 year olds
7. UK National Screening Committee
• Further literature consideration
sent in as part of consultation comments was considered by the external
reviewers and final recommendation brought to the UK NSC in May 2015.
• Recommendation
• The UK NSC does not recommend a systematic population screening
programme for Sudden Cardiac Death.
• There are serious limitations in the literature on fundamental issues
relating to the condition, test, intervention and cost-effectiveness of a
screening programme.
7 Sudden Cardiac Death Screening in 12 to 39 year olds
8. Recent News and Studies
• Van Brabandt et al. 2016 Harms and Benefits of Screening Young People to
Prevents Sudden Cardiac Death.
• 2016 National Collegiate Athletic Association (USA) consensus guidelines
• American College of Cardiology and American Heart Association do not
recommend routine, large scale ECGs.
• Recommend taking family history and physical examination.
8 Sudden Cardiac Death Screening in 12 to 39 year olds
9. What Might Screening Look Like?...
Van Brabandt et al. 2016 Belgium Study
9 Sudden Cardiac Death Screening in 12 to 39 year olds
Infographic reproduced, with permission, from Van Brabandt et al. 2016 HTA study
of potential SCD screening in Belgium
10. References
1. https://legacyscreening.phe.org.uk/suddencardiacdeath
2. Van Brabandt et al. 2016 , H. Desomer, A. Gerkens S. and Neyt, M (2016)
Harms and Benefits of Screening Young People to Prevents Sudden
Cardiac Death, BMJ, 2016;353:i1158
3. Infographic reproduced from Van Brabandt et al. 2016
https://kce.fgov.be/sites/default/files/page_documents/KCE_241Cs_sportscr
eening_Synthesis_0.pdf
10 Sudden Cardiac Death Screening in 12 to 39 year olds