This document summarizes the organization and structure of skeletal muscle. It describes that skeletal muscles are composed of bundles of long, cylindrical muscle cells called muscle fibers. Each muscle fiber contains thin filaments of actin and thick filaments of myosin that slide past each other during muscle contraction. Contraction occurs via a sliding filament mechanism where myosin heads hydrolyze ATP and attach to actin, generating a power stroke that shortens the muscle. Calcium release activates contraction by allowing the myosin heads to bind actin.
Muscles is a contractile tissue which brings about movement.
Muscle cell responsible for our movement both visible and invisible, example walking, talking, bowel movement ,urination, breathing, heartbeats, the dilation and constriction of the pupils of our eyes and many other.
When we are still sitting or standing muscle cells keep us erect.
CONT...Muscles can be regarded as motors of the body.Muscles comprises about 40% to 50% (approximate) of body weight.There are approximate 650 muscles in body.Alternating contraction and relaxation of cells
1. The muscular system has three main functions: produce movements, maintain posture, and generate heat.
2. There are three main types of muscle in the human body: skeletal, smooth, and cardiac muscle.
3. Skeletal muscle is attached to bones and controls voluntary movement, while smooth and cardiac muscles control involuntary functions like digestion and heart rate.
Muscular tissue contributes to homeostasis through body movements, moving substances through the body, and producing heat. There are three types of muscle - skeletal, smooth, and cardiac. Skeletal muscle is attached to bones and controls movement, smooth muscle is found in organs and blood vessels, and cardiac muscle is only found in the heart. Muscle fibers contract through a sliding filament mechanism where actin and myosin filaments interact through cross bridges to shorten the muscle. Calcium release triggers muscle contraction by exposing actin binding sites on the thin filaments.
The document discusses the muscular system and muscular tissue. It covers three types of muscle tissue - skeletal, cardiac, and smooth muscle - and their distinct characteristics, locations, and functions. Skeletal muscle is composed of parallel bundles of fibers bound by connective tissue sheaths. Contraction occurs via the sliding filament model, where actin and myosin filaments slide past each other, shortening the sarcomere. Calcium release triggers the power stroke and ATP hydrolysis powers crossbridge cycling during contraction and relaxation. The document also examines muscle energetics and the role of cellular respiration, glycolysis, and the phosphocreatine shuttle in regenerating ATP during activity.
Functional and anatomy of skeletal muscleRohit Paswan
The muscular system allows for body movement, maintenance of posture, respiration, communication, organ and vessel constriction, and heat production. There are three main types of muscle - skeletal, smooth, and cardiac. Skeletal muscle is striated, attached to bones, and responsible for voluntary movement. Smooth muscle is involuntary and found within organs and blood vessels. Cardiac muscle is found only in the heart. Muscles contract through a sliding filament mechanism where actin and myosin filaments interact in a cross-bridge cycle facilitated by calcium release from the sarcoplasmic reticulum.
Muscle Contraction and Movement_Enzymes.pptKimEliakim1
1. The document describes the molecular characteristics and mechanisms of muscle contraction. It discusses the structure and interactions of the contractile filaments actin and myosin.
2. The sliding filament theory is described as the mechanism where myosin heads bind to actin and hydrolyze ATP to slide along actin, causing muscle shortening.
3. The process of muscle contraction involves motor neuron stimulation, calcium ion release, actin-myosin cross-bridge formation, and sarcomere shortening through the sliding of actin and myosin filaments.
This document summarizes the organization and structure of skeletal muscle. It describes that skeletal muscles are composed of bundles of long, cylindrical muscle cells called muscle fibers. Each muscle fiber contains thin filaments of actin and thick filaments of myosin that slide past each other during muscle contraction. Contraction occurs via a sliding filament mechanism where myosin heads hydrolyze ATP and attach to actin, generating a power stroke that shortens the muscle. Calcium release activates contraction by allowing the myosin heads to bind actin.
Muscles is a contractile tissue which brings about movement.
Muscle cell responsible for our movement both visible and invisible, example walking, talking, bowel movement ,urination, breathing, heartbeats, the dilation and constriction of the pupils of our eyes and many other.
When we are still sitting or standing muscle cells keep us erect.
CONT...Muscles can be regarded as motors of the body.Muscles comprises about 40% to 50% (approximate) of body weight.There are approximate 650 muscles in body.Alternating contraction and relaxation of cells
1. The muscular system has three main functions: produce movements, maintain posture, and generate heat.
2. There are three main types of muscle in the human body: skeletal, smooth, and cardiac muscle.
3. Skeletal muscle is attached to bones and controls voluntary movement, while smooth and cardiac muscles control involuntary functions like digestion and heart rate.
Muscular tissue contributes to homeostasis through body movements, moving substances through the body, and producing heat. There are three types of muscle - skeletal, smooth, and cardiac. Skeletal muscle is attached to bones and controls movement, smooth muscle is found in organs and blood vessels, and cardiac muscle is only found in the heart. Muscle fibers contract through a sliding filament mechanism where actin and myosin filaments interact through cross bridges to shorten the muscle. Calcium release triggers muscle contraction by exposing actin binding sites on the thin filaments.
The document discusses the muscular system and muscular tissue. It covers three types of muscle tissue - skeletal, cardiac, and smooth muscle - and their distinct characteristics, locations, and functions. Skeletal muscle is composed of parallel bundles of fibers bound by connective tissue sheaths. Contraction occurs via the sliding filament model, where actin and myosin filaments slide past each other, shortening the sarcomere. Calcium release triggers the power stroke and ATP hydrolysis powers crossbridge cycling during contraction and relaxation. The document also examines muscle energetics and the role of cellular respiration, glycolysis, and the phosphocreatine shuttle in regenerating ATP during activity.
Functional and anatomy of skeletal muscleRohit Paswan
The muscular system allows for body movement, maintenance of posture, respiration, communication, organ and vessel constriction, and heat production. There are three main types of muscle - skeletal, smooth, and cardiac. Skeletal muscle is striated, attached to bones, and responsible for voluntary movement. Smooth muscle is involuntary and found within organs and blood vessels. Cardiac muscle is found only in the heart. Muscles contract through a sliding filament mechanism where actin and myosin filaments interact in a cross-bridge cycle facilitated by calcium release from the sarcoplasmic reticulum.
Muscle Contraction and Movement_Enzymes.pptKimEliakim1
1. The document describes the molecular characteristics and mechanisms of muscle contraction. It discusses the structure and interactions of the contractile filaments actin and myosin.
2. The sliding filament theory is described as the mechanism where myosin heads bind to actin and hydrolyze ATP to slide along actin, causing muscle shortening.
3. The process of muscle contraction involves motor neuron stimulation, calcium ion release, actin-myosin cross-bridge formation, and sarcomere shortening through the sliding of actin and myosin filaments.
Unit Three - Excitable Tissues (Muscle).pptWasihun Aragie
Muscles contribute to homeostasis through movement, substance transport, and heat generation. Muscle contraction occurs when skeletal muscle fibers shorten via the sliding of thick and thin myofilaments past each other within sarcomeres. There are three types of muscle tissue - skeletal, cardiac, and smooth muscle - which differ in structure and control. Skeletal muscle is striated and voluntary, cardiac muscle is striated and involuntary, and smooth muscle is non-striated and involuntary.
This document summarizes key aspects of muscle and skeletal physiology:
1. It describes the skeletal and muscular systems, including the types of bones, joints, ligaments, and tendons that make up the skeletal system.
2. It explains the structure and function of skeletal muscle, including the roles of actin, myosin, sarcomeres, and calcium in muscle contraction.
3. It outlines the sliding filament theory of muscle contraction, where myosin cross-bridges attaching to and pulling on actin fibers causes sarcomere shortening and muscle contraction.
Skeletal muscle has several key functions including body movement, posture, respiration, communication, organ constriction, and heart beat. Muscle tissue is excitable, contractile, extensible, and elastic. The three main types of muscle are skeletal, smooth, and cardiac. Skeletal muscle is voluntary, striated, and attaches to bones to enable movement. It makes up around 40% of body weight. Smooth muscle is involuntary and found within organs. Cardiac muscle is involuntary and pumps blood throughout the heart. Muscles contain myofibrils which are made up of repeating contractile units called sarcomeres composed of actin and myosin filaments. Nerve impulses trigger calcium release and the sliding
Describes the action potential occuring in the muscle. It includes the cellular and molecular organization of the muscle particularly on the myosin and actin myofilaments. Describes likewise the steps of muscle contraction.
There are three main types of muscle in the human body - skeletal, cardiac, and smooth muscle.
Skeletal muscle is striated and voluntary, attaching to bones to enable movement. Cardiac muscle is also striated and found only in the heart, contracting involuntarily to pump blood. Smooth muscle is non-striated and involuntary, surrounding internal organs to aid processes like digestion and blood flow. All three muscle types contract through the sliding filament mechanism of actin and myosin but differ in structure, control, and function.
The document provides an overview of the muscular system, including:
1. It describes the three main types of muscle - skeletal, cardiac, and smooth muscle - and their functions. Skeletal muscle is voluntary and controls movement, cardiac muscle involuntarily pumps blood, and smooth muscle involuntarily controls organs.
2. The structure of muscle is explained from the microscopic level of actin and myosin filaments up to the whole muscle level of fascicles and tendons. Key components that allow contraction are also defined.
3. The sliding filament model of muscle contraction is described, involving calcium signaling, cross-bridge cycling of actin and myosin, and the generation of force. Relaxation occurs when
Muscle tissue consists of elongated muscle cells called fibers that have the ability to contract. The main types are skeletal, cardiac, and smooth muscle. Skeletal muscle is striated and voluntary, attaching to bones to enable movement. Cardiac muscle is also striated but involuntary, found only in the heart walls. Smooth muscle is non-striated and involuntary, surrounding hollow organs. All muscle tissues contain contractile filaments that slide past each other during contraction, but the structures differ between tissue types.
The muscular system is composed of three types of muscles - skeletal, cardiac, and smooth muscle. Skeletal muscle allows for movement by contracting and shortening. It is organized into fascicles containing bundles of striated muscle fibers. Muscle fibers contain myofibrils made up of overlapping actin and myosin filaments that slide past each other during contraction. Contraction is initiated when a nerve impulse causes calcium release and the heads of myosin filaments form cross-bridges with actin to generate force through the hydrolysis of ATP. Aging can lead to muscle loss but exercise can help build muscle mass. Disorders of muscle include muscular dystrophy and myasthenia gravis.
This document provides information about muscle tissues and the neuromuscular junction. It discusses the three types of muscle tissues - skeletal, cardiac, and smooth muscle. It describes the structure and function of skeletal muscle fibers and their organization into myofibrils, filaments, and sarcomeres. The sliding filament mechanism of muscle contraction is explained. It also describes the neuromuscular junction where motor neurons signal skeletal muscle fibers through the release of acetylcholine.
Molecular basis of Skeletal Muscle ContractionArulSood2
The ppt aims to explain the molecular basis of skeletal muscle contraction and certain applied aspects of the same. Sources include Guyton and Hall's Textbook of Physiology (South-Asia edition, Vol. 2) and C.L. Ghai's Textbook for Practical Physiology.
- Muscle is divided into three types: skeletal, cardiac, and smooth. Skeletal muscle contractions are stimulated by nerves while cardiac and smooth muscles can contract independently.
- Skeletal muscle fibers are long, cylindrical, and multinucleated. They contain bundled myofibrils which are made of repeating sarcomere units. Sarcomeres contain thin actin and thick myosin filaments that slide past each other during contraction.
- Contraction is initiated by an action potential which causes calcium release from the sarcoplasmic reticulum. Calcium binds to troponin and tropomyosin, exposing actin binding sites for myosin heads to attach via ATP hydrolysis, causing sarcomere shortening and
Skeletal muscle is voluntary muscle that is attached to bones and controls movement. It comprises 40-50% of body weight and there are approximately 650 muscles. Skeletal muscle contracts and relaxes in alternating fashion using ATP to generate movement.
Cardiac muscle is involuntary muscle found only in the heart. It has a striated appearance and coordinates contractions to pump blood through the circulatory system. Cardiac muscle cells connect through intercalated discs to contract in a wave-like pattern.
Smooth muscle is involuntary muscle found in organs and passageways like the stomach, intestines, arteries and veins. It controls involuntary functions like digestion and regulates blood flow. Smooth muscle lacks striations and responds to chemical and neural stimuli for
This document provides an outline for a lecture on the muscular system. It discusses the main functions of the three types of muscle tissue - skeletal, smooth, and cardiac. Key points include the sliding filament model of muscle contraction, motor unit structure and function, and an overview of the anatomy of the sarcomere and myofilaments. The summary highlights the main muscle types and their functions as well as the sliding filament model of contraction.
This document provides an introduction to skeletal muscle structure and function. It discusses the following key points in 3 sentences or less:
Skeletal muscle forms about 50% of body weight, is voluntary and striated, and its main functions are tension development and shortening under nervous system control. Skeletal muscle is composed of bundles of muscle fibers which contain myofibrils made up of repeating structural units called sarcomeres, the basic contractile units of muscle. Each sarcomere contains thin actin filaments and thick myosin filaments arranged in a repeating pattern that gives skeletal muscle its striated appearance visible under electron microscopy.
Locomotion is the voluntary movement of organisms that results in a change of position. It occurs through locomotory movements like walking, running, climbing, flying, and swimming. Muscles enable locomotion and have properties like excitability, contractility, extensibility, and elasticity. There are three main types of muscles - skeletal muscles which are striated and attached to bones, visceral muscles which are smooth and located in organs, and cardiac muscles which make up the heart. Skeletal muscles enable locomotion through contraction initiated by motor neurons in the nervous system.
Muscular tissue is composed of muscle fibers that contract in response to electrical signals. There are three types of muscle tissue - skeletal, cardiac, and smooth muscle. Skeletal muscle is striated, voluntary, and attached to bones. It contracts through a sliding filament mechanism where actin and myosin interact powered by ATP hydrolysis. At the neuromuscular junction, a nerve impulse triggers the release of acetylcholine which binds receptors and generates a muscle action potential, causing contraction.
This document summarizes the key characteristics and functions of the three main types of muscle tissue: skeletal, cardiac, and smooth muscle. It provides detailed information on their structure, including cellular components like myofibrils, sarcomeres, and organelles. The main differences are that skeletal muscle is striated and voluntary, cardiac muscle is striated and involuntary, and smooth muscle lacks striations and is involuntary. Both skeletal and cardiac muscle show cross-striations while smooth muscle does not.
Muscle tissue is divided into three primary types - skeletal, cardiac, and smooth muscle. Skeletal muscle is organized into motor units controlled by the nervous system and allows for voluntary movement. Contraction occurs when calcium ions are released, causing the thin and thick myofilaments to interact via cross-bridges, sliding the filaments and shortening the sarcomere. The amount of tension produced depends on factors like sarcomere length, stimulation frequency, and number of motor units recruited. Energy for muscle contraction is obtained primarily through aerobic metabolism of fats and carbohydrates.
Anatomy and Physiology of Muscle by Prasanjit Shom.pptxPRASANJIT SHOM
This document summarizes the anatomy and physiology of muscle. It describes the three main types of muscle - skeletal, smooth, and cardiac. It then focuses on the structure and function of skeletal muscle. Key points include that skeletal muscle is made of fascicles and fibers containing myofibrils and sarcomeres. Sarcomeres contain thin actin filaments and thick myosin filaments. Contraction occurs via a cross-bridge cycle in which calcium release allows myosin to interact with and pull on actin, shortening the muscle.
Skeletal muscle is composed of individual muscle fibers (myocytes) arranged in bundles and covered by connective tissue. Each muscle fiber contains contractile myofibrils made up of repeating sarcomere units. The sarcomere contains thin actin filaments and thick myosin filaments that overlap to allow muscle contraction when myosin heads attach to actin and move the filaments past each other using ATP energy. Other proteins such as tropomyosin, troponin and titin regulate the interaction of actin and myosin to control contraction.
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
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Similar to StructureofSkeletalMuscle for presentation.ppt
Unit Three - Excitable Tissues (Muscle).pptWasihun Aragie
Muscles contribute to homeostasis through movement, substance transport, and heat generation. Muscle contraction occurs when skeletal muscle fibers shorten via the sliding of thick and thin myofilaments past each other within sarcomeres. There are three types of muscle tissue - skeletal, cardiac, and smooth muscle - which differ in structure and control. Skeletal muscle is striated and voluntary, cardiac muscle is striated and involuntary, and smooth muscle is non-striated and involuntary.
This document summarizes key aspects of muscle and skeletal physiology:
1. It describes the skeletal and muscular systems, including the types of bones, joints, ligaments, and tendons that make up the skeletal system.
2. It explains the structure and function of skeletal muscle, including the roles of actin, myosin, sarcomeres, and calcium in muscle contraction.
3. It outlines the sliding filament theory of muscle contraction, where myosin cross-bridges attaching to and pulling on actin fibers causes sarcomere shortening and muscle contraction.
Skeletal muscle has several key functions including body movement, posture, respiration, communication, organ constriction, and heart beat. Muscle tissue is excitable, contractile, extensible, and elastic. The three main types of muscle are skeletal, smooth, and cardiac. Skeletal muscle is voluntary, striated, and attaches to bones to enable movement. It makes up around 40% of body weight. Smooth muscle is involuntary and found within organs. Cardiac muscle is involuntary and pumps blood throughout the heart. Muscles contain myofibrils which are made up of repeating contractile units called sarcomeres composed of actin and myosin filaments. Nerve impulses trigger calcium release and the sliding
Describes the action potential occuring in the muscle. It includes the cellular and molecular organization of the muscle particularly on the myosin and actin myofilaments. Describes likewise the steps of muscle contraction.
There are three main types of muscle in the human body - skeletal, cardiac, and smooth muscle.
Skeletal muscle is striated and voluntary, attaching to bones to enable movement. Cardiac muscle is also striated and found only in the heart, contracting involuntarily to pump blood. Smooth muscle is non-striated and involuntary, surrounding internal organs to aid processes like digestion and blood flow. All three muscle types contract through the sliding filament mechanism of actin and myosin but differ in structure, control, and function.
The document provides an overview of the muscular system, including:
1. It describes the three main types of muscle - skeletal, cardiac, and smooth muscle - and their functions. Skeletal muscle is voluntary and controls movement, cardiac muscle involuntarily pumps blood, and smooth muscle involuntarily controls organs.
2. The structure of muscle is explained from the microscopic level of actin and myosin filaments up to the whole muscle level of fascicles and tendons. Key components that allow contraction are also defined.
3. The sliding filament model of muscle contraction is described, involving calcium signaling, cross-bridge cycling of actin and myosin, and the generation of force. Relaxation occurs when
Muscle tissue consists of elongated muscle cells called fibers that have the ability to contract. The main types are skeletal, cardiac, and smooth muscle. Skeletal muscle is striated and voluntary, attaching to bones to enable movement. Cardiac muscle is also striated but involuntary, found only in the heart walls. Smooth muscle is non-striated and involuntary, surrounding hollow organs. All muscle tissues contain contractile filaments that slide past each other during contraction, but the structures differ between tissue types.
The muscular system is composed of three types of muscles - skeletal, cardiac, and smooth muscle. Skeletal muscle allows for movement by contracting and shortening. It is organized into fascicles containing bundles of striated muscle fibers. Muscle fibers contain myofibrils made up of overlapping actin and myosin filaments that slide past each other during contraction. Contraction is initiated when a nerve impulse causes calcium release and the heads of myosin filaments form cross-bridges with actin to generate force through the hydrolysis of ATP. Aging can lead to muscle loss but exercise can help build muscle mass. Disorders of muscle include muscular dystrophy and myasthenia gravis.
This document provides information about muscle tissues and the neuromuscular junction. It discusses the three types of muscle tissues - skeletal, cardiac, and smooth muscle. It describes the structure and function of skeletal muscle fibers and their organization into myofibrils, filaments, and sarcomeres. The sliding filament mechanism of muscle contraction is explained. It also describes the neuromuscular junction where motor neurons signal skeletal muscle fibers through the release of acetylcholine.
Molecular basis of Skeletal Muscle ContractionArulSood2
The ppt aims to explain the molecular basis of skeletal muscle contraction and certain applied aspects of the same. Sources include Guyton and Hall's Textbook of Physiology (South-Asia edition, Vol. 2) and C.L. Ghai's Textbook for Practical Physiology.
- Muscle is divided into three types: skeletal, cardiac, and smooth. Skeletal muscle contractions are stimulated by nerves while cardiac and smooth muscles can contract independently.
- Skeletal muscle fibers are long, cylindrical, and multinucleated. They contain bundled myofibrils which are made of repeating sarcomere units. Sarcomeres contain thin actin and thick myosin filaments that slide past each other during contraction.
- Contraction is initiated by an action potential which causes calcium release from the sarcoplasmic reticulum. Calcium binds to troponin and tropomyosin, exposing actin binding sites for myosin heads to attach via ATP hydrolysis, causing sarcomere shortening and
Skeletal muscle is voluntary muscle that is attached to bones and controls movement. It comprises 40-50% of body weight and there are approximately 650 muscles. Skeletal muscle contracts and relaxes in alternating fashion using ATP to generate movement.
Cardiac muscle is involuntary muscle found only in the heart. It has a striated appearance and coordinates contractions to pump blood through the circulatory system. Cardiac muscle cells connect through intercalated discs to contract in a wave-like pattern.
Smooth muscle is involuntary muscle found in organs and passageways like the stomach, intestines, arteries and veins. It controls involuntary functions like digestion and regulates blood flow. Smooth muscle lacks striations and responds to chemical and neural stimuli for
This document provides an outline for a lecture on the muscular system. It discusses the main functions of the three types of muscle tissue - skeletal, smooth, and cardiac. Key points include the sliding filament model of muscle contraction, motor unit structure and function, and an overview of the anatomy of the sarcomere and myofilaments. The summary highlights the main muscle types and their functions as well as the sliding filament model of contraction.
This document provides an introduction to skeletal muscle structure and function. It discusses the following key points in 3 sentences or less:
Skeletal muscle forms about 50% of body weight, is voluntary and striated, and its main functions are tension development and shortening under nervous system control. Skeletal muscle is composed of bundles of muscle fibers which contain myofibrils made up of repeating structural units called sarcomeres, the basic contractile units of muscle. Each sarcomere contains thin actin filaments and thick myosin filaments arranged in a repeating pattern that gives skeletal muscle its striated appearance visible under electron microscopy.
Locomotion is the voluntary movement of organisms that results in a change of position. It occurs through locomotory movements like walking, running, climbing, flying, and swimming. Muscles enable locomotion and have properties like excitability, contractility, extensibility, and elasticity. There are three main types of muscles - skeletal muscles which are striated and attached to bones, visceral muscles which are smooth and located in organs, and cardiac muscles which make up the heart. Skeletal muscles enable locomotion through contraction initiated by motor neurons in the nervous system.
Muscular tissue is composed of muscle fibers that contract in response to electrical signals. There are three types of muscle tissue - skeletal, cardiac, and smooth muscle. Skeletal muscle is striated, voluntary, and attached to bones. It contracts through a sliding filament mechanism where actin and myosin interact powered by ATP hydrolysis. At the neuromuscular junction, a nerve impulse triggers the release of acetylcholine which binds receptors and generates a muscle action potential, causing contraction.
This document summarizes the key characteristics and functions of the three main types of muscle tissue: skeletal, cardiac, and smooth muscle. It provides detailed information on their structure, including cellular components like myofibrils, sarcomeres, and organelles. The main differences are that skeletal muscle is striated and voluntary, cardiac muscle is striated and involuntary, and smooth muscle lacks striations and is involuntary. Both skeletal and cardiac muscle show cross-striations while smooth muscle does not.
Muscle tissue is divided into three primary types - skeletal, cardiac, and smooth muscle. Skeletal muscle is organized into motor units controlled by the nervous system and allows for voluntary movement. Contraction occurs when calcium ions are released, causing the thin and thick myofilaments to interact via cross-bridges, sliding the filaments and shortening the sarcomere. The amount of tension produced depends on factors like sarcomere length, stimulation frequency, and number of motor units recruited. Energy for muscle contraction is obtained primarily through aerobic metabolism of fats and carbohydrates.
Anatomy and Physiology of Muscle by Prasanjit Shom.pptxPRASANJIT SHOM
This document summarizes the anatomy and physiology of muscle. It describes the three main types of muscle - skeletal, smooth, and cardiac. It then focuses on the structure and function of skeletal muscle. Key points include that skeletal muscle is made of fascicles and fibers containing myofibrils and sarcomeres. Sarcomeres contain thin actin filaments and thick myosin filaments. Contraction occurs via a cross-bridge cycle in which calcium release allows myosin to interact with and pull on actin, shortening the muscle.
Skeletal muscle is composed of individual muscle fibers (myocytes) arranged in bundles and covered by connective tissue. Each muscle fiber contains contractile myofibrils made up of repeating sarcomere units. The sarcomere contains thin actin filaments and thick myosin filaments that overlap to allow muscle contraction when myosin heads attach to actin and move the filaments past each other using ATP energy. Other proteins such as tropomyosin, troponin and titin regulate the interaction of actin and myosin to control contraction.
Similar to StructureofSkeletalMuscle for presentation.ppt (20)
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Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
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His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
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Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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The simplified electron and muon model, Oscillating Spacetime: The Foundation...RitikBhardwaj56
Discover the Simplified Electron and Muon Model: A New Wave-Based Approach to Understanding Particles delves into a groundbreaking theory that presents electrons and muons as rotating soliton waves within oscillating spacetime. Geared towards students, researchers, and science buffs, this book breaks down complex ideas into simple explanations. It covers topics such as electron waves, temporal dynamics, and the implications of this model on particle physics. With clear illustrations and easy-to-follow explanations, readers will gain a new outlook on the universe's fundamental nature.
A workshop hosted by the South African Journal of Science aimed at postgraduate students and early career researchers with little or no experience in writing and publishing journal articles.
2. Introduction
• All activities that involve movement depend on muscles
• 650 muscles in the human body
• Various purposes for muscles for:
– Locomotion
– Upright posture
– Balancing on two legs
– Support of internal organs
– Controlling valves and body openings
– Production of heat
– Movement of materials along internal tubes
• Three types of muscles in the human body
– Skeletal
– Cardiac
– Smooth
3. Skeletal Muscle
• Skeletal muscles are
muscles which are
attached to the skeleton.
• 40% of human body mass
• Skeletal muscles are
mainly responsible for
locomotion, and voluntary
contraction and relaxation.
4. Structure of Skeletal muscles
• Skeletal muscles are composed of clusters of muscle
cells.
– Muscle fibers
– Myofibers
– Myocytes
• A muscle consists of packages of muscle cells called
fascicles
• A muscle cell is long and spindle shaped
5. Structure of Skeletal muscles
• Cell structure
– Muscles cells contain many nuclei
– The plasma membrane→ sarcolemma
– The cytoplasm→ sarcoplasm
– Length
– ranges from 0.1cm to more the 30cm in length
– Diameter
– ranges from 0.001cm to 0.01cm in diameter
• Myofibrils→
– elongated protein molecules
– aligned in parallel arrangements
– extend the full length of the cell.
6.
7.
8. Structure of Skeletal muscles
• The myofibril consists of protein
chains called myofilaments
– Myofilaments have a symmetrical,
alternating pattern of thick and thin
elements.
9. Skeletal Muscle Myosin
• Thick myofilament
• consists of a large number of bundled myosin molecules aligned
in overlapping arrays.
• hexameric proteins with two identical heavy chains and two pairs of
different light chains.
– regulatory light chain (RLC)
– essential light chain (ELC)
10. Skeletal Muscle Actin
• The thin myofilament (F-actin, filamentous actin)
– made up of two helically intertwined chains of G-actin (globular
actin) units.
• Other proteins that bind to the actin molecules:
• Tropomyosin
• The Troponin complex→ made up of three members
11.
12. Contraction of Skeletal Muscle
• The thick and thin filaments, along with their associated myofibril
proteins, are responsible for muscle contraction.
• How does muscle contraction work?
– Influx of calcium ions in the cell
• as a result of nerve impulses
– troponin complex pulls tropomyosin molecules away from the G-actin
subunits
– Exposure of the myosin binding sites.
– The heads of the myosin molecules can bind to the actin subunits,
forming cross bridges.
• active site in each myosin head disrupts the high-energy bond of
ATP molecules
• release of energy moves the myosin head towards the F- actin,
• when contact is made with the actin subunits, the F-actin is pulled
along, causing the myofilament to contract.
• The coordinated contraction of all the myofilaments of all the
muscle cells of a muscle, causes the entire muscle to contract.
13.
14. Relaxation of Skeletal Muscle
– Calcium ions are carried
away from the myofilaments
– Myosin- actin linkages
loosen
– The troponin complex and
tropomyosin bind to the
myosin binding sites on the
F-actin subunits,
• Myosin and F- actin
myofilaments return to
their original positions
15. References:
• Pasternak, Jack J. Human Molecular Genetics: Mechanisms of
Inherited Diseases. Hoboken, New Jersey: John Wilkey &
Sons Inc., 2005.
• http://www.lau-verlag.de/anatom/muscleb.jpg. March, 20, 2006