This document discusses status epilepticus and contains 10 multiple choice questions about treatments for status epilepticus. It addresses first, second, and third line drugs for treatment including lorazepam, fosphenytoin, midazolam, valproate, phenobarbitone, and thiopentone. It also covers definitions of refractory status epilepticus, drugs used for intubation, correct drug doses, characteristics of non-convulsive status epilepticus, side effects of sodium valproate, causes of newborn convulsions, and mechanisms not responsible for benzodiazepine-induced hypotension.

1. Status Epilepticus

2. 1.Tremor and tachyphylaxis is
associated with which of the
following anticonvulsant ??
A. Midazolam
B. Sodium Valproate
C. Phenytoin
D. Fosphenytoin

3. 2.Which of the following
statements is NOT true??
A. Advantage of fosphenytoin over
phenytoin is due to the addition of
propylene glycol
B. Lorazepam is less lipophilic ,less
protein bound and has less volume
of distribution
C. High dose thiopentone may be
immunosuppressive
D. Topiramate is a carbonic anhydrase
inhibitor

4. 3.Best First line second line
thirdline ??
A. Lorazepam fosphenytoin Midazolam
B. Lorazepam High dose
phenobarbitonethiopentone
C. Lorazepam valproate standard dose
phenobarbitone
D. Midazolam Topiramate  thiopentone
infusion

5. 4.Refractory Status is lasts
A. >30 min
B. >40 min
C. >50 min
D. >60 min
….despite optimal therapy with first and
second line drugs

6. 5.Muscle relaxant used while
intubating a child throwing
seizures
A. Rocuronium
B. Succinylcholine
C. Carisoprodol
D. Chlormezanone

7. 6.Which of the drug dose
combination is not correct?
A. Lorazepam  0.1mg/kg/dose IV
B. Midazolam  0.2mg/kg/dose IM
C. Fosphenytoin  30mg/kg/dose IV
over 10 min
D. Thiopentone 0.15mg/kg slowly IV

8. 7.False about NCSE??
A. Treatment is same as convulsive
status
B. Suspect NCSE if a patient fails to
achieve consciosness 30 – 60 min
after cessation of convulsive status
C. Chewing movements of mouth is a
presentation of NCSE
D. Pupillary abnormalities are not seen
in NCSE

9. 8. Side effect of sodium
valproate includes all EXCEPT ?
A. Thrombocytopenia
B. Encephalopathy
C. Neuropsychiatric symptoms
D. Pancreatitis

10. 9. Most common cause of
convulsion on the first day of life
A. Anoxia
B. Head injury
C. Hypoglycemia
D. Hypocalcemia

11. 10.BZD induced hypotension is
NOT due to
A. Peripheral vasodilatation
B. Negative inotropy
C. Sedation induced blunting of the
stress related catacholamines
D. None of the above