This document discusses skeletal maturity indicators that can be used to assess a patient's biological age and remaining growth potential. It describes how chronological age alone is not enough, and that skeletal age determined from hand wrist radiographs provides a more accurate assessment. The document outlines several methods for assessing skeletal age, including the Fishman skeletal maturity indicators and the Modified MP3 Cervical Vertebrae Maturation Index. It explains what each method evaluates and the stages involved. Assessing skeletal age is important for orthodontic treatment planning to determine treatment timing and prognosis.