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Single-stage laparoscopic
management for concomitant
gallstones and common bile
duct stones versus two stages
using ERCP procedures
PRESENTED BY/
DR. MOHAMED TAG ELDIN MOHAMED SAYED
MD RESEARCHER SOHAGE UNIVERSITY HOSPITAL
GENERAL SURGERY SPECIALIST QENA GENERAL HOSPITAL
Introduction
 About 10–15% of patients with gallstones present with
concomitant common bile duct stones.
 Of more concern is the management of these CBD
stones, which had been debated for years since the
introduction of laparoscopic cholecystectomy in the late
1980s.
( Chester Tan et al, 2018)
 Management strategy of common duct stones
involves either endoscopic common duct
clearance followed by removal of the
gallbladder surgically or surgical exploration
and clearance of the CBD. Surgical exploration
can be done by open choledocholithotomy or
laparoscopically.
( Kadam R et al, 2017)
 Endoscopic stone extraction followed by laparoscopic
cholecystectomy (ERCP + LC) was the standard of
care for patients with gall stones and CBD stones.
 However, with increasing expertise in laparoscopic
procedures, more and more surgeons have started
offering a single-stage laparoscopic CBD exploration
and cholecystectomy (LCBDE) to patients.
(Singh, A.N. & Kilambi, R.,2018)
 At present, it is really equivocal with the handful
evidence that whether or not two-stage
management is preferable to or otherwise
comparable to the one-stage operative procedure
for CBD stones.
(Pankaj Prasson et al, 2016)
Aim of Work
 The aim of this study is to compare between the outcome of
management of concomitant gallstones and common bile duct
by two stage (ERCP+LC) versus one stage (LECBD+LC)
Patients and Methods
 This study included 150
patients with concomitant
gallstones and CBD stones who
were treated at Sohag
University hospital from July
2017 to December 2018.
Criteria for inclusion
Age 16 to 70 years.
Patients with or without Jaundice.
Patients with gallbladder stones and concomitant
stones in the CBD.
CBD diameter ≥1cm.
Criteria for exclusion
 Acute cholecystitis.
 Acute pancreatitis.
 Uncorrectable coagulopathy.
 Liver cirrhosis, intrahepatic gallbladder, liver mass or
abscess, neoplasm.
 Recurrent CBD stones.
 Malignant pancreatic or biliary tumors.
 Group A (75 patients) underwent single-stage laparoscopic
CBD exploration (LCBDE) and laparoscopic cholecystectomy
(LC).
 Group B (75 patients) underwent a two-stage procedure;
ERCP for endoscopic extraction of CBD stones followed by
LC (ERCP + LC) within the same hospital admission.
Results
Group A (LCBDE)
Trocar arrangement
Sometimes, direct puncture for the basket or facial closure
forceps retractionTrocars are applied as that for cholecystectomy
The item Number Percent
Trans-cystic approach 8 10.6%
Trans-choledochotomy approach 67 89.4%
Choledochoscopic technique 45 60%
Cholangiogram 22 29.3%
Direct access 8 10.7%
Total 75 100%
Trans-cystic approach Incision of the
cystic duct
Ureteric catheter cannulation of cystic
duct
Contrast injection (diluted urographine
solution)
Trans-cystic basket extraction of the
CBD stone
Trans-choledochotomy approach
Dissection of cystic/hepatic duct communication
Choledochotomy using protected Scalpel
Choledochotomy using protected diathermy
hook
 The choledochoscope used (Pentax
choledochoscope)
Choledochoscope is manipulated through
choledochotomy to CBD lumen using
atraumatic grasper
CBD stones as visualized by the
choledochoscope within CBD
Through choledochoscope basket extraction of the CBD
stone to outside CBD
Proximal assurance of CBD clearance by
choledochoscope
Direct stone manipulation by basket through
choledochotomy without Choledochoscopy
Stone extraction by direct access
without choledochoscope help
T-tube application
T-tube deployment through CBD lumen
Choledochal suturing above and below
T-tube choledochotomy
Choledochorrhaphy and primary CBD
closure
Primary closure using V-lock suture
Postoperative view
Group B (ERCP+LC)
ERCP Scope
ERCP- balloon extraction
ERCP- Basket extraction
ERCP- balloon and basket extraction
ERCP multiple stone extraction
ERCP- Lithotripsy
Laparoscopic Cholecystectomy
Postoperative view
Comparison in
• Intraoperative complications
• Conversion to other procedure
• Total operative time
• Postoperative complications
• Postoperative mortality
• Retained CBD stones
• Length of hospital stay
• Patient satisfaction
Group A (LCBDE) Group B (ERCP+LC)
Success rates for clearance of CBD 97.3% 98.7%
Intraoperative complications 1.3% hemorrhage 2.6% hemorrhage during Lap.
Cholecystectomy
Conversion to other procedure 2.6% 4% (conversion of lap.
Cholecystectomy to open)
Total operative time 115.7 ± 36.6 min 82.4 ± 27.6 min
Postoperative pain • 24h: 3.4 ± 1.7 (rang 1-7)
• 3days: 0.6 ± 0.9(rang 0-2)
• 24h 4.8 ± 1.8 (rang 2–7)
• 3days 0.7 ± 0.8 (rang 0–3)
Postoperative complications Transient bile leak 6.6% • Transient bile leak 2.6 %
• Acute pancreatitis 5.3%
Postoperative mortality Nil Nil
Retained CBD stones 2.6% Nil
Length of hospital stay 4.6 ± 2.4 days 5.3 ± 6.2 days
Patient satisfaction 1.62 ± 0.3(rang 1-5) 1.94 ± 0.7(rang 1-7)
Summary
 The success rates of laparoscopic CBD exploration and ERCP for
clearance of CBD were comparable.
 The mean operative time was significantly longer in-group A but the
overall hospital stay was significantly shorter.
 As regard intraoperative complications there were no significant
difference between Group A(1.3% hemorrhage) vs. group B (2.6%
hemorrhage).
 As for conversion to other procedure for group A less than for group B
but statically insignificant.
 Post-operative pain recorded in group A less than group B but statically
insignificant.
 Postoperative complications rates between the two groups were
comparable, Group A showed (Transient bile leak 6.6%) vs Group B
(Transient bile leak 2.6 %, Acute pancreatitis 5.3%).
 Two patients (2.6%) in-group A had a diagnosis of retained stones
determined during follow up.
 The patients in-group A had higher satisfaction scores than the patients
in-group B.
Conclusions
 Single and two-stage management for uncomplicated
concomitant gallbladder and CBD stones had similar success
and complication rates, but the single stage strategy was
better in terms of shorter hospital stay, need for fewer
procedures, less morbidity, and allows earlier recovery with a
reduced period of short-term disability.
Thank you all
with special thanks to my senior
supervisor
Prof. Alaa Redwan
Professor of GIT surgery and
laparoendoscopy
Faculty of medicine, Sohag University

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Single stage laparoscopic management for concomitant gallstones and common bile duct stones versus two stages using ercp procedures

  • 1. Single-stage laparoscopic management for concomitant gallstones and common bile duct stones versus two stages using ERCP procedures PRESENTED BY/ DR. MOHAMED TAG ELDIN MOHAMED SAYED MD RESEARCHER SOHAGE UNIVERSITY HOSPITAL GENERAL SURGERY SPECIALIST QENA GENERAL HOSPITAL
  • 2. Introduction  About 10–15% of patients with gallstones present with concomitant common bile duct stones.  Of more concern is the management of these CBD stones, which had been debated for years since the introduction of laparoscopic cholecystectomy in the late 1980s. ( Chester Tan et al, 2018)
  • 3.  Management strategy of common duct stones involves either endoscopic common duct clearance followed by removal of the gallbladder surgically or surgical exploration and clearance of the CBD. Surgical exploration can be done by open choledocholithotomy or laparoscopically. ( Kadam R et al, 2017)
  • 4.  Endoscopic stone extraction followed by laparoscopic cholecystectomy (ERCP + LC) was the standard of care for patients with gall stones and CBD stones.  However, with increasing expertise in laparoscopic procedures, more and more surgeons have started offering a single-stage laparoscopic CBD exploration and cholecystectomy (LCBDE) to patients. (Singh, A.N. & Kilambi, R.,2018)
  • 5.  At present, it is really equivocal with the handful evidence that whether or not two-stage management is preferable to or otherwise comparable to the one-stage operative procedure for CBD stones. (Pankaj Prasson et al, 2016)
  • 6. Aim of Work  The aim of this study is to compare between the outcome of management of concomitant gallstones and common bile duct by two stage (ERCP+LC) versus one stage (LECBD+LC)
  • 7. Patients and Methods  This study included 150 patients with concomitant gallstones and CBD stones who were treated at Sohag University hospital from July 2017 to December 2018.
  • 8. Criteria for inclusion Age 16 to 70 years. Patients with or without Jaundice. Patients with gallbladder stones and concomitant stones in the CBD. CBD diameter ≥1cm.
  • 9. Criteria for exclusion  Acute cholecystitis.  Acute pancreatitis.  Uncorrectable coagulopathy.  Liver cirrhosis, intrahepatic gallbladder, liver mass or abscess, neoplasm.  Recurrent CBD stones.  Malignant pancreatic or biliary tumors.
  • 10.  Group A (75 patients) underwent single-stage laparoscopic CBD exploration (LCBDE) and laparoscopic cholecystectomy (LC).
  • 11.  Group B (75 patients) underwent a two-stage procedure; ERCP for endoscopic extraction of CBD stones followed by LC (ERCP + LC) within the same hospital admission.
  • 13. Group A (LCBDE) Trocar arrangement Sometimes, direct puncture for the basket or facial closure forceps retractionTrocars are applied as that for cholecystectomy
  • 14. The item Number Percent Trans-cystic approach 8 10.6% Trans-choledochotomy approach 67 89.4% Choledochoscopic technique 45 60% Cholangiogram 22 29.3% Direct access 8 10.7% Total 75 100%
  • 15. Trans-cystic approach Incision of the cystic duct
  • 17. Contrast injection (diluted urographine solution)
  • 18. Trans-cystic basket extraction of the CBD stone
  • 19. Trans-choledochotomy approach Dissection of cystic/hepatic duct communication
  • 22.  The choledochoscope used (Pentax choledochoscope)
  • 23. Choledochoscope is manipulated through choledochotomy to CBD lumen using atraumatic grasper
  • 24. CBD stones as visualized by the choledochoscope within CBD
  • 25. Through choledochoscope basket extraction of the CBD stone to outside CBD
  • 26. Proximal assurance of CBD clearance by choledochoscope
  • 27. Direct stone manipulation by basket through choledochotomy without Choledochoscopy
  • 28. Stone extraction by direct access without choledochoscope help
  • 31. Choledochal suturing above and below T-tube choledochotomy
  • 33. Primary closure using V-lock suture
  • 38. ERCP- balloon and basket extraction
  • 39. ERCP multiple stone extraction
  • 43. Comparison in • Intraoperative complications • Conversion to other procedure • Total operative time • Postoperative complications • Postoperative mortality • Retained CBD stones • Length of hospital stay • Patient satisfaction
  • 44. Group A (LCBDE) Group B (ERCP+LC) Success rates for clearance of CBD 97.3% 98.7% Intraoperative complications 1.3% hemorrhage 2.6% hemorrhage during Lap. Cholecystectomy Conversion to other procedure 2.6% 4% (conversion of lap. Cholecystectomy to open) Total operative time 115.7 ± 36.6 min 82.4 ± 27.6 min Postoperative pain • 24h: 3.4 ± 1.7 (rang 1-7) • 3days: 0.6 ± 0.9(rang 0-2) • 24h 4.8 ± 1.8 (rang 2–7) • 3days 0.7 ± 0.8 (rang 0–3) Postoperative complications Transient bile leak 6.6% • Transient bile leak 2.6 % • Acute pancreatitis 5.3% Postoperative mortality Nil Nil Retained CBD stones 2.6% Nil Length of hospital stay 4.6 ± 2.4 days 5.3 ± 6.2 days Patient satisfaction 1.62 ± 0.3(rang 1-5) 1.94 ± 0.7(rang 1-7)
  • 45. Summary  The success rates of laparoscopic CBD exploration and ERCP for clearance of CBD were comparable.  The mean operative time was significantly longer in-group A but the overall hospital stay was significantly shorter.  As regard intraoperative complications there were no significant difference between Group A(1.3% hemorrhage) vs. group B (2.6% hemorrhage).  As for conversion to other procedure for group A less than for group B but statically insignificant.
  • 46.  Post-operative pain recorded in group A less than group B but statically insignificant.  Postoperative complications rates between the two groups were comparable, Group A showed (Transient bile leak 6.6%) vs Group B (Transient bile leak 2.6 %, Acute pancreatitis 5.3%).  Two patients (2.6%) in-group A had a diagnosis of retained stones determined during follow up.  The patients in-group A had higher satisfaction scores than the patients in-group B.
  • 47. Conclusions  Single and two-stage management for uncomplicated concomitant gallbladder and CBD stones had similar success and complication rates, but the single stage strategy was better in terms of shorter hospital stay, need for fewer procedures, less morbidity, and allows earlier recovery with a reduced period of short-term disability.
  • 48. Thank you all with special thanks to my senior supervisor Prof. Alaa Redwan Professor of GIT surgery and laparoendoscopy Faculty of medicine, Sohag University