The document summarizes research on the role of the nkx2.5 gene in zebrafish heart development. The researcher found that nkx2.5 expression is essential for normal heart development during a 15 hour window between 7 somites (11 hpf) and 26 hpf. Activating a transgenic nkx2.5 gene within this window rescued zebrafish embryos with nkx2.5 mutations, restoring normal heart morphology. However, the long term effects on rescued embryos are unknown. The timing results provide insight into treating human congenital heart defects caused by NKX2.5 mutations.