Shakespeare's plays remain popular 400 years after his death because the themes and situations presented still resonate with modern audiences. Some of the most enduring themes in his works include love, revenge, lust for power, and the basic nature of humanity. While some things have changed since Shakespeare's time, such as advances in medicine and views on gender, the core human experiences he explored still apply to people today. As a result, Shakespeare's plays maintain their relevance in the modern world.