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SEROLOGY
● Performs tests to evaluate the body’s immune response; that is, the production of
antibodies (immunoglobulins) and cellular activation.
● The section is frequently called serology rather than by the broader term
immunology because most tests performed in this section analyze for the presence
of antibodies in serum
● Tests in the serology section detect the presence of antibodies to bacteria, fungi,
parasites, viruses, and antibodies produced against body substances (autoimmunity).
Serology (Immunology)
Sample Collection and Handling
• Blood for serological testing is collected in tubes with
red stoppers.
• Serum separator tubes are not used when the gel will
interfere with the antigen-antibody reactions.
Tests Performed in
the Serology
(Immunology)
Section
● Screening test for human immunodeficiency virus
Anti- HIV
Antinuclear antibody (ANA)
● Detects nuclear autoantibodies
● Detects a previous streptococcus infection
Antistreptolysin O (AOS) Screen
C-reactive Protein (CRP)
● Elevated levels indicate inflammatory disorders
● elevated levels indicate atypical (mycoplasma) pneumonia
Cold agglutinins
Complement levels
● evaluate the function of the immune system
● detects cytomegalovirus infection
Cytomegalovirus antibody (CMV)
Febrile agglutinin
● detects antibodies to microorganisms causing fever
● Detects and identifies nuclear autoantibodies
Fluorescent antinuclear antibody (FANA)
Fluorescent treponemal antibody-absorbed (FTA-ABS)
● Confirmatory test for syphilis
● Detects hepatitis A current or past infection
Hepatitis A antibody
Hepatitis B surface antigen (HBsAg)
● Detects hepatitis B infection
● Detects hepatitis C infection
Hepatitis C antibody
Human chorionic gonadotropic (HCG)
● Hormone found in the urine and serum during pregnancy
● Evaluate function of the immune system
Immunoglobulin levels
Monospot
● Screening test for infectious mononucleosis
● Screening test for Syphilis
Rapid plasma reagin (RPR)
Rheumatoid Arthritis (RA)
● Detects autoantibodies present in rheumatoid arthritis
● Evaluates immunity to German measles
Rubella titer
Venereal Disease Research Laboratory ( VDRL)
● Screening test for syphilis
Western blot
● Confirmatory test for human immunodeficiency virus
CREDITS: This presentation template was created by
Slidesgo, including icons by Flaticon, and infographics
& images by Freepik.
Thanks
Members:
Alysa Ilano
Alemar Langco
Kian Lawrence Lugo
Regina Mariah Otake
Bessie May Quijano
Venisse Velayo
Catherine Catacutan
GR.6: SEROLOGY

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SEROLOGY_GR.6.pptx

  • 2. ● Performs tests to evaluate the body’s immune response; that is, the production of antibodies (immunoglobulins) and cellular activation. ● The section is frequently called serology rather than by the broader term immunology because most tests performed in this section analyze for the presence of antibodies in serum ● Tests in the serology section detect the presence of antibodies to bacteria, fungi, parasites, viruses, and antibodies produced against body substances (autoimmunity). Serology (Immunology)
  • 3. Sample Collection and Handling • Blood for serological testing is collected in tubes with red stoppers. • Serum separator tubes are not used when the gel will interfere with the antigen-antibody reactions.
  • 4. Tests Performed in the Serology (Immunology) Section
  • 5.
  • 6. ● Screening test for human immunodeficiency virus Anti- HIV Antinuclear antibody (ANA) ● Detects nuclear autoantibodies
  • 7. ● Detects a previous streptococcus infection Antistreptolysin O (AOS) Screen C-reactive Protein (CRP) ● Elevated levels indicate inflammatory disorders
  • 8. ● elevated levels indicate atypical (mycoplasma) pneumonia Cold agglutinins Complement levels ● evaluate the function of the immune system
  • 9. ● detects cytomegalovirus infection Cytomegalovirus antibody (CMV) Febrile agglutinin ● detects antibodies to microorganisms causing fever
  • 10. ● Detects and identifies nuclear autoantibodies Fluorescent antinuclear antibody (FANA) Fluorescent treponemal antibody-absorbed (FTA-ABS) ● Confirmatory test for syphilis
  • 11. ● Detects hepatitis A current or past infection Hepatitis A antibody Hepatitis B surface antigen (HBsAg) ● Detects hepatitis B infection
  • 12. ● Detects hepatitis C infection Hepatitis C antibody Human chorionic gonadotropic (HCG) ● Hormone found in the urine and serum during pregnancy
  • 13. ● Evaluate function of the immune system Immunoglobulin levels Monospot ● Screening test for infectious mononucleosis
  • 14. ● Screening test for Syphilis Rapid plasma reagin (RPR) Rheumatoid Arthritis (RA) ● Detects autoantibodies present in rheumatoid arthritis
  • 15. ● Evaluates immunity to German measles Rubella titer Venereal Disease Research Laboratory ( VDRL) ● Screening test for syphilis
  • 16. Western blot ● Confirmatory test for human immunodeficiency virus
  • 17. CREDITS: This presentation template was created by Slidesgo, including icons by Flaticon, and infographics & images by Freepik. Thanks Members: Alysa Ilano Alemar Langco Kian Lawrence Lugo Regina Mariah Otake Bessie May Quijano Venisse Velayo Catherine Catacutan GR.6: SEROLOGY