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SEIZUREJireh Jessieca Faith A. Bascuña
•INTRODUCTION
•CLASSIFICATIONS
INTRODUCTION
A"seizure"results"from"
sudden,'explosive,'
disorderly)discharge)of)
cerebral'neurons.
INTRODUCTION
Characterized+by:""
!sudden,!transient!alteration!
in#brain#function,#involving##
MOTOR,&SENSORY,&
AUTONOMIC)OR)PHYSICAL)
CLINICAL&MANIFESTATION
INTRODUCTION
PEDIATRIC)NEUROLOGY)
!high%incidence%
Most% people:first% episode%
starts%before%20%yrs%old.%
After& 20& y.o:& caused& by!
structural( change,trauma,(
tumor,'or'stroke.'
INTRODUCTION
POSSIBLE(CAUSES(
Metabolic*derangements,*Infections,*
tumors,( Drug( abuse,( Vascular(
lesions,(Congenital(deformities,(and(
Brain%injury
SEIZURE VS EPILEPSY
SEIZURE:"
single' event! of! abnormal! discharge!
that$ results$ in$ an$ abrupt," altered"
state%of%cerebral%function.!
EPILEPSY:""
chronic' disorder! of! recurrent!
discharges* from* neurons.! Present!
when% 2" or" more" unprovoked!
seizures' occur' at' an' interval' greater'
than%24%hours%apart.
• measured( by(
the$EEG.$!!
• usually&brief
• periodic( recurrence( of(
seizures' with' or' without'
convulsions)

•
• are$ violent,$ involuntary$
contractions) of) the)
voluntary*muscles.*!
• A" patient" may" have"
epilepsy' or' a' seizure'
d i s o r d e r' w i t h o u t'
convulsions.*

SEIZURE | EPILEPSY | CONVULSION
•Clinical'manifestations'
•Site%of%origin%
•EEG#correlates,#or#
•Response'to'therapy
CLASSIFICATIONS
based on:
Generalized!
occurring( in( and( rapidly( engaging( bilaterally(
distributed)networks.)
Focal&(Partial)!!
within&networks&limited&to&one&hemisphere&and&either&
discretely*localized*or*more*widely*distributed.*
CLASSIFICATIONSInternational*League*Against*Epilepsy
I.#Partial!
a.#Simple#
b.#Complex#
CLASSIFICATIONS
International*Classi&ication+of+Epileptic+Seizures
II.#Generalized!
a.#Absence#
b.#Myoclonic#
c.#Tonic#
d.#Clonic#
e.#Tonic)#Clonic#
f.#Atonic
III.#Unclassi+ied!
I. PARTIAL SEIZURES
No#loss#of#consciousness
• Motor
convulsive*jerking,*chewing*motions,!
!and!lip$smacking.$
• Sensory(&(somatosensory paresthesias)and)auras
• Autonomic sweating,*+lushing,*and*pupil*dilation.*
• Behavioral
sometimes' accompanied' by' impaired'
consciousness,) include) déjà) vu)
experiences,* structured* hallucinations,*
and$dysphasia.$
a.#SIMPLE#PARTIAL#SEIZURES:
b.#COMPLEX(PARTIAL(SEIZURES
I. PARTIAL SEIZURES
b.#COMPLEX(PARTIAL(SEIZURES
violence
aggressive(behavior
Purposeless)behavior
glassy&stare
speak&unintelligibly!
!with&loss$of$consciousness.
B. GENERALIZED SEIZURES
Three%types
affecting)both)cerebral)hemispheres.)
(1) Idiopathic epilepsies
(2) Symptomatic epilepsies
(3) Cryptogenic epilepsies
*Incidence:)Some)patients)experience)100)or)more)absences)daily.))
*Onset:(age(3(to(16(years;(in(most(patients,(may(disappear(by(age(40.(
Typical:!blank!stare,!motionlessness,!and!unresponsiveness
Automatisms:"lip"smacking,"mild"clonic"motion"(usually"in"eyelids)
!ABSENCE!(PETIT!MAL)!SEIZURES!
alterations*of*consciousness*(absences)*for*10330*secs.*
Myoclonic((bilateral(massive(epileptic(myoclonus)!seizures(!involuntary!jerking!of!the!facial,!
limb,&or&trunk&muscles,&possibly&in&a&rhythmic&manner.&
Myoclonic( (bilateral( massive( epileptic( myoclonus)! seizures(! involuntary!
jerking(of(the(facial,(limb,(or(trunk(muscles,(possibly(in(a(rhythmic(manner.(

TONIC&SEIZURE
CLONIC!SEIZURES
!"sustained"tonic"muscle"
extension((stiffening).
!"sustained"muscle"contractions"
alternating) with) relaxation.!
(jerking)
TONIC&PHASE
CLONIC&PHASE
POSTICTAL)PHASE
GRAND&MALGRAND&MAL
headache,'confusion,'disorientation,'nausea,'drowsiness,'and'muscle'soreness
a"sudden"loss"of"postural"tone"so"the"individual"falls"
to#the#ground.#They#occur#primarily#in#children.
Atonic'seizures!(drop!attacks)
TRADITIONAL TERMINOLOGY NEW NOMENCLATURE
Focal; Jacksonian Seizure Partial
Temporal lobe or Psychomotor
seizure
Complex
Petit mal Absence
Grand mal Tonic-clonic
Drop attack Atonic
FYI!
LABORATORY(TEST:(
After&GTC&seizures:&Serum&prolactin&levels&is&elevated.!!
Importance+of+Lab+test—!to!rule!out!treatable!causes!of!seizures!!
(e.g.,& hypoglycemia,& altered& serum& electrolyte& concentrations,&
infections,*etc.)*that*do*not*represent*epilepsy.**
Seizure

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Seizure