The document describes sbv IMPROVER, an initiative led by Philip Morris International that uses crowdsourcing to verify scientific data and methods. It provides examples of past challenges that asked participants to verify biological networks and diagnostic signatures. The initiative aims to complement peer review and drive innovation through collaboration. It works by engaging scientists through online challenges, publications, conferences and incentives to collaboratively refine computational models and methods.
Putting Research into Practice: The Plant Breeding and Genomics Community of ...jfuzzy
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Excerpts in a custom social listening engagement with GE Life-sciences around Protein Purification. This uses our proprietary Language based approach to bring structure to a large body of scientific text data.
Introduction to the adverse outcome pathways concept and framework, Catherine...OECD Environment
On 30 April 2019, the OECD organised a webinar on the Adverse Outcome Pathway (AOP) framework. The AOP framework is a collaborative tool that applies an innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment.
The following questions were addressed:
What is the AOP framework and why should you care?
Why are we developing AOPs?
Why collaborations are encouraged and why should scientific societies be brought in?
What are the opportunities for collaboration in AOP development?
OECD Webinar | From Data to Knowledge and Beyond Adverse Outcome Pathways as ...OECD Environment
On 23 and 30 November 2020, the OECD hosted a webinar on training needs, resources, and opportunities for adverse outcomes pathways (AOPs). This interactive webinar discussed opportunities for expanding the AOP community of trainers to meet current needs, considering all available resources.
The objectives of this webinar were to:
- outline past and current training activities
- receive your input on experiences in conducting and/or receiving training; and
- gather your views, needs and ideas for the provision of training in the future.
Watch the webinar video recording at: https://youtu.be/7ObxATifDds.
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Putting Research into Practice: The Plant Breeding and Genomics Community of ...jfuzzy
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The following questions were addressed:
What is the AOP framework and why should you care?
Why are we developing AOPs?
Why collaborations are encouraged and why should scientific societies be brought in?
What are the opportunities for collaboration in AOP development?
OECD Webinar | From Data to Knowledge and Beyond Adverse Outcome Pathways as ...OECD Environment
On 23 and 30 November 2020, the OECD hosted a webinar on training needs, resources, and opportunities for adverse outcomes pathways (AOPs). This interactive webinar discussed opportunities for expanding the AOP community of trainers to meet current needs, considering all available resources.
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- outline past and current training activities
- receive your input on experiences in conducting and/or receiving training; and
- gather your views, needs and ideas for the provision of training in the future.
Watch the webinar video recording at: https://youtu.be/7ObxATifDds.
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Antibiotic Discovery Webinar – Getting Through the Discovery WallLixin Liu
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Adverse outcome pathways collaboration, Jason O’Brien from the Environment an...OECD Environment
On 30 April 2019, the OECD organised a webinar on the Adverse Outcome Pathway (AOP) framework. The AOP framework is a collaborative tool that applies an innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment.
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What is the AOP framework and why should you care?
Why are we developing AOPs?
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Updated Agenda- CRISPR Congress in Berlin, 24-26 October 2016Diane McKenna
The Only Industry Event Solely Dedicated to Optimising the Applications CRISPR Precision Genome Editing in Europe.
Overcome key specificity, efficiency & delivery challenges to pioneer drug discovery, biomedical research and therapeutic applications of precision genome engineering. With customisation of CRISPR design paramount, join leading biopharma and academic figureheads as they reveal advanced methodology, strategies and clinical timelines to fulfil the revolutionary promise of precision genome editing.
This is a presentation from the Canadian Bovine Genomics Workshop held in Calgary, Alberta on Sept.14, 2009.
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Adverse Outcome Pathways Development Tips - Dan Villeneuve, US Environmental ...OECD Environment
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Drug Discovery Data Insights with Andrew Leach (ChEMBL), Evan Bolton (PubChem...Lixin Liu
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Application of adverse outcome pathways in chemical risk assessment, Dan Vill...OECD Environment
On 30 April 2019, the OECD organised a webinar on the Adverse Outcome Pathway (AOP) framework. The AOP framework is a collaborative tool that applies an innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment.
The following questions were addressed:
What is the AOP framework and why should you care?
Why are we developing AOPs?
Why collaborations are encouraged and why should scientific societies be brought in?
What are the opportunities for collaboration in AOP development?
Tools to Retrieve relevant AOP information - Holly Mortensen, US Environmenta...OECD Environment
This third webinar in the series of Adverse Outcome Pathways (AOPs) was organised on Thursday 30 January 2020. It focused on the core information and telecommunication technologies applications that were built to support AOP development, management and dissemination. Tools and technical tips to facilitate scientific knowledge assembling and evaluations were also presented. The AOP framework implements a collaborative and innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment. Holly Mortensen from the US Environmental Protection Agency presented ways of retrieving information from databases and other AOP tools.
We describe what we have learned from four years of collaborating across the industry/not-for-profit boundary. Over this time we pursued multiple projects and some of the lessons learned are described here.
Many large pharma companies have reduced their research activity at the very early, hit- and lead- seeking phase of research. To compensate, organisations are becoming more porous and working more collaboratively in risk-sharing arrangements. Both parties need to give up some control, but gain a great deal in return
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Adverse outcome pathways collaboration, Jason O’Brien from the Environment an...OECD Environment
On 30 April 2019, the OECD organised a webinar on the Adverse Outcome Pathway (AOP) framework. The AOP framework is a collaborative tool that applies an innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment.
The following questions were addressed:
What is the AOP framework and why should you care?
Why are we developing AOPs?
Why collaborations are encouraged and why should scientific societies be brought in?
What are the opportunities for collaboration in AOP development?
Updated Agenda- CRISPR Congress in Berlin, 24-26 October 2016Diane McKenna
The Only Industry Event Solely Dedicated to Optimising the Applications CRISPR Precision Genome Editing in Europe.
Overcome key specificity, efficiency & delivery challenges to pioneer drug discovery, biomedical research and therapeutic applications of precision genome engineering. With customisation of CRISPR design paramount, join leading biopharma and academic figureheads as they reveal advanced methodology, strategies and clinical timelines to fulfil the revolutionary promise of precision genome editing.
This is a presentation from the Canadian Bovine Genomics Workshop held in Calgary, Alberta on Sept.14, 2009.
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How to model longevity and health effect in 3 monthsWenlan Hu
Healthspan analysis is a huge part of longevity study, which is heavily looked at by many aging labs in recent years. The older we grow, our health will be affected accordingly, and this influence what type of compound we use. To better picture what effects compounds brings to us and to extend lifespan as a goal. A three stage compound assessment is developed by IVB to solve this question.
Excited to share our vision for bioinformatics education available for students and researchers that want to apply advanced multi-omics integration and machine learning to large biomedical datasets. Practice and learn from real-life projects.
Adverse Outcome Pathways Development Tips - Dan Villeneuve, US Environmental ...OECD Environment
This third webinar in the series of Adverse Outcome Pathways (AOPs) was organised on Thursday 30 January 2020. It focused on the core information and telecommunication technologies applications that were built to support AOP development, management and dissemination. Tools and technical tips to facilitate scientific knowledge assembling and evaluations were also presented. The AOP framework implements a collaborative and innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment. Dan Villeneuve from the US Environmental Protection Agency provided some tips on the development of AOPs
Drug Discovery Data Insights with Andrew Leach (ChEMBL), Evan Bolton (PubChem...Lixin Liu
The emergence of freely available PubChem and ChEMBL resources for chemical and biological Structure-Activity-Relationship (SAR) data has radically changed the global drug discovery informatics landscape. The heterogeneity of low throughput and high throughput chemical and biological data do nevertheless present some unique challenges – and opportunities – when creating large-scale community resources – for sophisticated purveyors of drug discovery data.
Application of adverse outcome pathways in chemical risk assessment, Dan Vill...OECD Environment
On 30 April 2019, the OECD organised a webinar on the Adverse Outcome Pathway (AOP) framework. The AOP framework is a collaborative tool that applies an innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment.
The following questions were addressed:
What is the AOP framework and why should you care?
Why are we developing AOPs?
Why collaborations are encouraged and why should scientific societies be brought in?
What are the opportunities for collaboration in AOP development?
Tools to Retrieve relevant AOP information - Holly Mortensen, US Environmenta...OECD Environment
This third webinar in the series of Adverse Outcome Pathways (AOPs) was organised on Thursday 30 January 2020. It focused on the core information and telecommunication technologies applications that were built to support AOP development, management and dissemination. Tools and technical tips to facilitate scientific knowledge assembling and evaluations were also presented. The AOP framework implements a collaborative and innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment. Holly Mortensen from the US Environmental Protection Agency presented ways of retrieving information from databases and other AOP tools.
We describe what we have learned from four years of collaborating across the industry/not-for-profit boundary. Over this time we pursued multiple projects and some of the lessons learned are described here.
Many large pharma companies have reduced their research activity at the very early, hit- and lead- seeking phase of research. To compensate, organisations are becoming more porous and working more collaboratively in risk-sharing arrangements. Both parties need to give up some control, but gain a great deal in return
A VIVO VIEW OF CANCER RESEARCH: Dream, Vision and RealityPaul Courtney
Presentation made by Paul Courtney (Dana-Farber Cancer Institute, Boston, MA and OHSL, MD) and Anil Srivastava (OHSL) at the 2013 VIVO conference in St. Louis, MO. Material contributed by Rubayi Srivastava (OHSL), Swati Mehta (Centre for Development of Advanced Computing, India), Juliusz Pukacki (Poznan Supercomputing and Network Center, Poland) and Devdatt Dubhashi (Chalmers Institute of Technology, Sweden).
Best Practices for Building an End-to-End Workflow for Microbial GenomicsJonathan Jacobs, PhD
Invited talk presented at 2019 CAFPA-ASM D.C. Branch
FALL MEETING on "Current Testing Approaches & Implications for Public Health" at the FDA in College Park, MD.
The webinar will include an introduction to COVID-END and an overview of how COVID-END’s resources can support you in your response to COVID-19. With tips, tools, and a guide to evidence sources for both researchers and decision-makers, COVID-END has something for everyone.
CRO Company for Mode of Action & Efficacy Test for Drugs | InvivoBiosystemsWenlan Hu
Compound testing takes shares of a huge part of the drug development and health-related compound market. In order to find a CRO that is both friendly for budget saving and efficient at the same time is not easy. IVB uses a three staged compound assessment which includes RNAseq, whole transcriptome analysis, and other techniques to help our clients better understand the mode of action and efficacy of a particular compound.
We have 13 research and development projects within:
• Research
• Oncology
• Respiratory, Inflammation and Autoimmunity
• Cardiovascular and Metabolic Disease
• Antibody Discovery and Protein Engineering
• Pathology
• Biopharmaceutical Development
• Cell Culture and Fermentation Sciences
• Formulation Sciences
• Analytical Biotechnology Science
The compound characterization market is growing increasingly profitable and competitive at the same time. In order to develop a new compound product, the testing step is indispensable. Unlike drug discovery, compound testing is not as restrictive, but understanding the main workflow is still necessary to excel in the market. In order to help you improve both the efficiency and safety of compound testing, we developed the protocol to assist you in your findings.
Journal Club - Best Practices for Scientific ComputingBram Zandbelt
Journal Club presentation for Cools lab at Donders Institute, Radboud University, Nijmegen, the Netherlands
Date: October 28, 2015
Paper:
Wilson, G., Aruliah, D. A., Brown, C. T., Hong, N. P. C., Davis, M., Guy, R. T., ... & Wilson, P. (2014). Best practices for scientific computing. PLoS Biology, 12(1), e1001745.
The NRNB has been funded as an NIGMS Biomedical Technology Research Resource since 2010. During the previous five-year period, NRNB investigators introduced a series of innovative methods for network biology including network-based biomarkers, network-based stratification of genomes, and automated inference of gene ontologies using network data. Over the next five years, we will seek to catalyze major phase transitions in how biological networks are represented and used, working across three broad themes: (1) From static to differential networks, (2) From descriptive to predictive networks, and (3) From flat to hierarchical networks bridging across scales. All of these efforts leverage and further support our growing stable of network technologies, including the popular Cytoscape network analysis infrastructure.
#InvitroStudies are critical to the #drug and #wellness product #development due to their ability to provide a basis for #clinical in vivo studies for predicting best delivery model to take Go/No-Go decision. #Our solution on in vitro analyses can provide proof of concept on delivery dosage form in the early stages or reverse pharmacology #development of the active process, when the selectively and possible interactions of the active process, when the selectivity and possible interactions of the candidate drug towards the desired therapeutic target are established. Our team can provide solution map on case to case basis for your specific requirement . For more details please visit on https://www.stabicon.com/In-Vitro.php
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PRESENTATION ABOUT PRINCIPLE OF COSMATIC EVALUATION
sbv IMPROVER: an industry initiative to harness the wisdom of the crowd in science
1. www.sbvimprover.com
sbv IMPROVER: an
industry initiative to
harness the power of the
crowd in science
Dr Stéphanie Boué, Manager Scientific Transparency
& Verification, Philip Morris International R&D
Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000
Neuchatel, Switzerland (Part of Philip Morris International
group of companies)
CSW – March 2018