Ben Busby is the founder of the Department of Bioinformatics and Data Science at NIH. He discusses several hackathon projects focused on analyzing RNAseq data and developing machine learning applications for genomics. These include tools for polygenic SNP search, genomic robots, and phenogenomics. Upcoming hackathons are planned on topics like RNAseq, human pan-genomics, variant datasets, and virus discovery. The goal is to create an open community around bioinformatics and data science.

1. Ben Busby, Ph.D.
Data Science Education Something…
NCBI et al
Founder, Department of Bioinformatics and Data Science, FAES
ben.busby@nih.gov, @dcgenomics, LinkedIn
Prototype ML Software for Analysis of RNAseq, and Development of RNAseq
for ML-ready Applications Developed in NIH-Hackathons!

2. Polygenic SNP Search Tool
https://github.com/NCBI-
Hackathons/PSST

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4. https://github.com/NCBI-
Hackathons/GenomicRobots

5. https://github.com/NCBI-Hackathons/Complex_Phenogeno

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7. phenvar.colorado.edu

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9. Combined score is
the average of SVs,
mappability, GC..
NCBI region list
Encode blacklist

11. https://github.com/NCBI-
Hackathons/ViruSpy

12. https://github.com/NCBI-
Hackathons/EndoVir

13. https://github.com/NCBI-
Hackathons/VirusFriends

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15. https://ncbi-hackathons.github.io/GeneExpressionAging/ideogram

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https://www.biorxiv.org/content/10.1101/461301v2

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Data Hackathons!

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Planned Events
RNAseq – UNC, March 11-13 2019;
Palo Alto, June 2019
Smaller events at USF and Pittsburgh
Human PanGenomics – UCSC, 25-27 March 2019;
Haplotype Annotation, Baltimore, June 2019
Variant Synthetic Dataset Generation –
Boston, April 15-16, 2019
AMR and Prokaryotic Genome Annotate-athon
NIH Campus, August 2019

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Virus Discovery!

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Data Hackathons!

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RNA-seq Indexing!

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RNA-seq Indexing!

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https://github.com/NCBI-Hackathons/RNA-Seq-in-the-Cloud

29. Creating a Community
https://biohackathons.github.io
MACHINE LEARNING
PROJECT MANAGEMENT
PRODUCT MANAGEMENT

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