The Regional Innovation Scoreboard provides a comparative assessment of innovation performance across 190 regions in Europe. It uses 11 indicators to measure regional innovation performance and groups regions into four categories: Regional Innovation leaders, Regional Innovation followers, Regional Moderate innovators, and Regional Modest innovators. For most regions, innovation performance improved over 2004-2010, though it declined for some. Regions with more positive attitudes toward new ideas and public support for innovation tend to be more innovative. The analysis also examines how regions leverage EU funding for research and innovation.