Rhinoplasty
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This document discusses the anatomy and assessment of rhinoplasty. It outlines the layers of the nose, including skin, muscle, and cartilage. It divides the nose into three sections - the upper, middle, and lower thirds. It also identifies red flags for patients such as those displaying SIMON traits, which could indicate unrealistic expectations of the procedure's outcome. Assessment involves examining the nose from multiple angles and measuring angles and distances to aid surgical planning.
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Cell Therapy Expansion and Challenges in Autoimmune Disease
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Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
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- 1. Anatomy & Assessment Rhinoplasty Mansoor Khan M.B.B.S Plastic & Reconstructive Surgery, Hayatabad Medical Complex, Peshawar
- 2. Skin , subcutaneous tissue, muscle, fascia, areolar tissue, perichondrium
- 3. Upper 1/3 Bony vault, Middle 1/3 Cartillagenous vault, Lower 1/3 Cartillagenous vault,
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