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Volume 4 • Issue 4 • 1000178
Biochem Pharmacol
ISSN:2167-0501 BCPC, an open access journal
Research Article Open Access
Biochemistry & Pharmacology: Open Access
Biochemistry
&
Pharmacology
:O
penAccess
ISSN: 2167-0501
Trivedi et al., Biochem Pharmacol (Los Angel) 2015, 4:4
http://dx.doi.org/10.4172/2167-0501.1000178
Abstract
m-toluic acid (MTA) is widely used in manufacturing of dyes, pharmaceuticals, polymer stabilizers, and insect
repellents. The aim of present study was to evaluate the impact of biofield treatment on physical, thermal and
spectroscopic properties of MTA. MTA sample was divided into two groups that served as treated and control. The
treated group received Mr. Trivedi’s biofield treatment. Subsequently, the control and treated samples were evaluated
using X-ray diffraction (XRD), surface area analyser, differential scanning calorimetry (DSC), thermogravimetric analysis
(TGA), Fourier transform infrared (FT-IR) and ultraviolet-visible (UV-Vis) spectroscopy. XRD result showed a decrease
in crystallite size in treated samples i.e. 42.86% in MTA along with the increase in peak intensity as compared to control.
However, surface area analysis showed an increase in surface area of 107.14% in treated MTA sample as compared to
control. Furthermore, DSC analysis results showed that the latent heat of fusion was considerably reduced by 40.32%,
whereas, the melting temperature was increased (2.23%) in treated MTA sample as compared to control. The melting
point of treated MTA was found to be 116.04°C as compared to control (113.51°C) sample. Moreover, TGA/DTG
studies showed that the control sample lost 56.25% of its weight, whereas, in treated MTA, it was found 58.60%. Also,
Tmax
(temperature, at which sample lost maximum of its weight) was decreased by 1.97% in treated MTA sample as
compared to control. It indicates that the vaporisation temperature of treated MTA sample might decrease as compared
to control. The FT-IR and UV-Vis spectra did not show any significant change in spectral properties of treated MTA
sample as compared to control. These findings suggest that biofield treatment has significantly altered the physical and
thermal properties of m-toluic acid, which could make them more useful as a chemical intermediate.
Physical, Thermal and Spectroscopic Characterization of m-Toluic Acid:
an Impact of Biofield Treatment
Mahendra Kumar Trivedi1
, Alice Branton1
, Dahryn Trivedi1
, Gopal Nayak1
, Ragini Singh2
and Snehasis Jana2
*
1
Trivedi Global Inc., 10624 S Eastern Avenue Suite A-969, Henderson, NV 89052, USA
2
Trivedi Science Research Laboratory Pvt. Ltd., Hall-A, Chinar Mega Mall, Chinar Fortune City, Hoshangabad Rd, Bhopal- 462026, Madhya Pradesh, India
*Corresponding author: Snehasis Jana, Trivedi Science Research Laboratory
Pvt. Ltd., Hall-A, Chinar Mega Mall, Chinar Fortune City, Hoshangabad Rd,
Bhopal- 462026, Madhya Pradesh, India, Tel: +91-755-666-0006; E-mail:
publication@trivedisrl.com
Received July 25, 2015; Accepted August 03, 2015; Published August 06, 2015
Citation: Trivedi MK, Branton A, Trivedi D, Nayak G, Singh R (2015) Physical,
Thermal and Spectroscopic Characterization of m-Toluic Acid: an Impact of Biofield
Treatmentr. Biochem Pharmacol (Los Angel) 4: 178. doi:10.4172/2167-0501.1000178
Copyright: © 2015 Trivedi MK, et al. This is an open-access article distributed under
the terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original author and
source are credited.
Keywords: Biofield treatment; m-Toluic acid; X-ray diffraction
study; Surface area analysis; Differential scanning calorimetry;
Thermogravimetric analysis; Fourier transform infrared spectroscopy;
Ultraviolet-visible spectroscopy
Introduction
The m-toluic acid (MTA) is a benzoic acid derivative having a floral
honey odour. Benzoic acid occurs naturally in many plants and its name
was also derived from a plant source i.e. Gum benzoin. Although it is
used as precursor to plasticizers, preservatives such as sodium benzoate,
it also has wide application in many pharmaceutical preparations meant
for treatment of fungal skin diseases, topical antiseptics, expectorants,
analgesics and decongestants [1,2]. The benzoic acid derivatives are
also very useful due to their bacteriostatic and fragrant properties. They
are used as intermediate in the production of various pharmaceuticals
having analgesic, antirheumatic and vasodilator properties [3].
MTA is used as a chemical intermediate in manufacturing of insect
repellent and plastic stabilizer in the chemical industry. It is also used
in the production of various chemicals like 3-carboxybenzaldehyde,
3-benzoylphenylacetic acid, 3-methylbenzophenone, and N,N-diethyl-
3-methylbenzamide etc. [4,5]. It is a main component of N,N-diethyl-
m-toluamide, commonly known as DEET, which is first insect repellent
that can be applied to skin or clothing and provide protection against
mosquitoes and other biting insects [6].
MTA is used as intermediate in various chemical reactions, hence
its rate of reaction plays a crucial role. It was reported previously that
any alteration in crystallite size and surface area can affect the kinetics
of reaction [7]. Moreover, the rate kinetics of any chemical reaction
also depends on the thermal properties of the intermediate chemical
compound i.e. latent heat of fusion, vaporisation temperature,
decomposition temperature etc. [8]. After considering the properties
andapplicationsofMTA,authorswantedtoinvestigateaneconomically
safe approach that could be beneficial to modify their physical, thermal
and spectral properties.
The concept of human bioenergy has its origin thousands of
years back. It is scientifically termed as the biologically produced
electromagnetic and subtle energy field that provides regulatory and
communication functions within the human organs [9]. It generates
through internal physiological processes such as blood flow, brain and
heart function, etc. Nowadays, many biofield therapies are in practice
for their possible therapeutic potentials such as enhanced personal
well-being, improved functional ability of arthritis patient, decreased
pain and anxiety [10-12]. The practitioners of these therapy claim that
the healers channel supraphysical energy and intentionally direct this
energy towards target [13]. Thus, a human has the ability to harness
the energy from environment or universe and can transmit into any
living or non-living object(s). The objects always receive the energy
and responding into useful way that is called biofield energy and the
process is known as biofield treatment.
Mr. Trivedi’s biofield treatment is well known and significantly
studied in different fields such as microbiology [14-16], agriculture
[17,18], and biotechnology [19]. Exposure to biofield energy caused an
increase in medicinal property, growth, and anatomical characteristics

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Research by Mahendra Kumar Trivedi - Physical, Thermal and Spectroscopic Characterization of m-Toluic Acid: an Impact of Biofield Treatment

  • 1. Volume 4 • Issue 4 • 1000178 Biochem Pharmacol ISSN:2167-0501 BCPC, an open access journal Research Article Open Access Biochemistry & Pharmacology: Open Access Biochemistry & Pharmacology :O penAccess ISSN: 2167-0501 Trivedi et al., Biochem Pharmacol (Los Angel) 2015, 4:4 http://dx.doi.org/10.4172/2167-0501.1000178 Abstract m-toluic acid (MTA) is widely used in manufacturing of dyes, pharmaceuticals, polymer stabilizers, and insect repellents. The aim of present study was to evaluate the impact of biofield treatment on physical, thermal and spectroscopic properties of MTA. MTA sample was divided into two groups that served as treated and control. The treated group received Mr. Trivedi’s biofield treatment. Subsequently, the control and treated samples were evaluated using X-ray diffraction (XRD), surface area analyser, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), Fourier transform infrared (FT-IR) and ultraviolet-visible (UV-Vis) spectroscopy. XRD result showed a decrease in crystallite size in treated samples i.e. 42.86% in MTA along with the increase in peak intensity as compared to control. However, surface area analysis showed an increase in surface area of 107.14% in treated MTA sample as compared to control. Furthermore, DSC analysis results showed that the latent heat of fusion was considerably reduced by 40.32%, whereas, the melting temperature was increased (2.23%) in treated MTA sample as compared to control. The melting point of treated MTA was found to be 116.04°C as compared to control (113.51°C) sample. Moreover, TGA/DTG studies showed that the control sample lost 56.25% of its weight, whereas, in treated MTA, it was found 58.60%. Also, Tmax (temperature, at which sample lost maximum of its weight) was decreased by 1.97% in treated MTA sample as compared to control. It indicates that the vaporisation temperature of treated MTA sample might decrease as compared to control. The FT-IR and UV-Vis spectra did not show any significant change in spectral properties of treated MTA sample as compared to control. These findings suggest that biofield treatment has significantly altered the physical and thermal properties of m-toluic acid, which could make them more useful as a chemical intermediate. Physical, Thermal and Spectroscopic Characterization of m-Toluic Acid: an Impact of Biofield Treatment Mahendra Kumar Trivedi1 , Alice Branton1 , Dahryn Trivedi1 , Gopal Nayak1 , Ragini Singh2 and Snehasis Jana2 * 1 Trivedi Global Inc., 10624 S Eastern Avenue Suite A-969, Henderson, NV 89052, USA 2 Trivedi Science Research Laboratory Pvt. Ltd., Hall-A, Chinar Mega Mall, Chinar Fortune City, Hoshangabad Rd, Bhopal- 462026, Madhya Pradesh, India *Corresponding author: Snehasis Jana, Trivedi Science Research Laboratory Pvt. Ltd., Hall-A, Chinar Mega Mall, Chinar Fortune City, Hoshangabad Rd, Bhopal- 462026, Madhya Pradesh, India, Tel: +91-755-666-0006; E-mail: publication@trivedisrl.com Received July 25, 2015; Accepted August 03, 2015; Published August 06, 2015 Citation: Trivedi MK, Branton A, Trivedi D, Nayak G, Singh R (2015) Physical, Thermal and Spectroscopic Characterization of m-Toluic Acid: an Impact of Biofield Treatmentr. Biochem Pharmacol (Los Angel) 4: 178. doi:10.4172/2167-0501.1000178 Copyright: © 2015 Trivedi MK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Keywords: Biofield treatment; m-Toluic acid; X-ray diffraction study; Surface area analysis; Differential scanning calorimetry; Thermogravimetric analysis; Fourier transform infrared spectroscopy; Ultraviolet-visible spectroscopy Introduction The m-toluic acid (MTA) is a benzoic acid derivative having a floral honey odour. Benzoic acid occurs naturally in many plants and its name was also derived from a plant source i.e. Gum benzoin. Although it is used as precursor to plasticizers, preservatives such as sodium benzoate, it also has wide application in many pharmaceutical preparations meant for treatment of fungal skin diseases, topical antiseptics, expectorants, analgesics and decongestants [1,2]. The benzoic acid derivatives are also very useful due to their bacteriostatic and fragrant properties. They are used as intermediate in the production of various pharmaceuticals having analgesic, antirheumatic and vasodilator properties [3]. MTA is used as a chemical intermediate in manufacturing of insect repellent and plastic stabilizer in the chemical industry. It is also used in the production of various chemicals like 3-carboxybenzaldehyde, 3-benzoylphenylacetic acid, 3-methylbenzophenone, and N,N-diethyl- 3-methylbenzamide etc. [4,5]. It is a main component of N,N-diethyl- m-toluamide, commonly known as DEET, which is first insect repellent that can be applied to skin or clothing and provide protection against mosquitoes and other biting insects [6]. MTA is used as intermediate in various chemical reactions, hence its rate of reaction plays a crucial role. It was reported previously that any alteration in crystallite size and surface area can affect the kinetics of reaction [7]. Moreover, the rate kinetics of any chemical reaction also depends on the thermal properties of the intermediate chemical compound i.e. latent heat of fusion, vaporisation temperature, decomposition temperature etc. [8]. After considering the properties andapplicationsofMTA,authorswantedtoinvestigateaneconomically safe approach that could be beneficial to modify their physical, thermal and spectral properties. The concept of human bioenergy has its origin thousands of years back. It is scientifically termed as the biologically produced electromagnetic and subtle energy field that provides regulatory and communication functions within the human organs [9]. It generates through internal physiological processes such as blood flow, brain and heart function, etc. Nowadays, many biofield therapies are in practice for their possible therapeutic potentials such as enhanced personal well-being, improved functional ability of arthritis patient, decreased pain and anxiety [10-12]. The practitioners of these therapy claim that the healers channel supraphysical energy and intentionally direct this energy towards target [13]. Thus, a human has the ability to harness the energy from environment or universe and can transmit into any living or non-living object(s). The objects always receive the energy and responding into useful way that is called biofield energy and the process is known as biofield treatment. Mr. Trivedi’s biofield treatment is well known and significantly studied in different fields such as microbiology [14-16], agriculture [17,18], and biotechnology [19]. Exposure to biofield energy caused an increase in medicinal property, growth, and anatomical characteristics