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International Journal of Electronics and Communication Engineering & Technology (IJECET),
ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME
177
REAL TIME ECG SIGNAL ANALYSIS BY USING NEW DATA
REDUCTION ALGORITHM FOR DIAGNOSIS OVER WPAN
Bhuvaneshwari R. Yadwade Dr. S.B.Patil
Dept of E & Tc Head of Electronics & Telecommunication Dept.
Dr.J.J.Magdum College of engg. Dr. J.J.Magdum College of engg.
Jaisingpur, Maharashtra, India Jaisingpur, Maharashtra,India
Mr. B.S.Patil Mr. A. R. Chivate
Head of Information Technology Dept. of Digital Electronics
PVPIT, Budhgaon B.V. B college of engg. & Technology, Hubali
Maharashtra, India Karnataka, India
ABSTRACT
A method to compress diagnostic information without losing data is required to store
and transmit them efficiently on a wireless personal area network (WPAN). An ECG contains
diagnostic information related to cardiac activity. As electrocardiogram (ECG) signals are
generally sampled with a frequency of over 200 Hz, an ECG signal compression method for
communications on WPAN, which uses feature points based on curvature, is proposed. The
feature points of P, Q, R, S, and T waves, which are critical components of the ECG signal,
have large curvature values compared to other vertexes. Thus, these vertexes were extracted
with the proposed method, which uses local extrema of curvatures. Furthermore, in order to
minimize reconstruction errors of the ECG signal, extra vertexes were added according to the
iterative vertex selection method. It was concluded that the vertexes selected by the proposed
method preserved all feature points of the ECG signals.
Keywords: Curvature, electrocardiogram (ECG), feature extraction, vertex.
I. INTRODUCTION
Extensive ECG signal data is not suitable for wireless personal area networks
(WPAN), because healthcare monitoring system requires a real-time process [1] – [5].
Electrocardiogram (ECG) represents cardiac electrical activity by a graph that contains pre-
diagnosis information of various cardiac diseases. ECG signal measures very large amounts
INTERNATIONAL JOURNAL OF ELECTRONICS AND
COMMUNICATION ENGINEERING & TECHNOLOGY (IJECET)
ISSN 0976 – 6464(Print)
ISSN 0976 – 6472(Online)
Volume 4, Issue 3, May – June, 2013, pp. 177-184
© IAEME: www.iaeme.com/ijecet.asp
Journal Impact Factor (2013): 5.8896 (Calculated by GISI)
www.jifactor.com
IJECET
© I A E M E
International Journal of Electronics and Communication Engineering & Technology (IJECET),
ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME
178
of data in a short period of time, because it typically has a higher than 200 Hz sampling
frequency.
In order to telecommunicate the extensive ECG signal on WPAN, it is needed to
compress the signal without loss of significant information for diagnosis. However,
compression distortion is able to cause misdiagnosis of healthcare monitoring system.
Therefore, the main features of the diagnostic value should be maintained within the
tolerance range.
Conventional ECG compression research contains the direct compression method,
transformational compression method and so on.
In order to delineate the accurate description of ECG signal, a variety of approaches,
such as those based on numerical differentiation, pattern recognition, and mathematical
models have been proposed. The direct compression method detects the redundancy of an
ECG signal and eliminates it in the time-domain. This approach contains a turning point (TP)
[6], amplitude-zone-time epoch coding (AZTEC) [7]; coordinate reduction time encoding
system (CORTES) [8], differential pulse code modulation (DPCM) [9], and etc. The
conversion compression method is based on spectrum analysis and energy distribution
analysis, which provide the detection of redundancy. Fourier transform, Walsh
transformation, wavelet transform, and Karhunen-Loeve transform are conventional
conversion compression methods [10]–[12]. The conventional ECG compression method is
able to generate distortion of important ECG components, such as P, Q, R, S, and T waves
[13], [14]. On the other hand, this paper proposes a P, Q, R, S, and T wave preserving
compression method based on local extrema of curvature. Also, the proposed method
supplements the vertexes using the iterative refinement method (IRM) to improve peak signal
to noise ratio (PSNR) in the compressed ECG signal. Experimental results using the
Massachusetts Institute of Technology-Beth Israel hospital (MIT-BIH) arrhythmia database
verify the superiority of proposed method.
International Journal of Electronics and Communication Engineering & Technology (IJECET),
ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME
179
This paper is described by the following contents. The proposed method, which is
based on curvature, is explained in Section II. Then, section III provides the experimental
results of the proposed method, and section IV makes the conclusion of this paper.
II. ECG SIGNAL COMPRESSION USING CURVATURE
A typical ECG signal has a P wave, QRS-complex, and T wave, all of which are
important component of a diagnosis (see Fig. 1). The start and end points of P, Q, R, S, and T
waves are important feature points for diagnosis of heart disease. These feature points have a
larger signal variation rate than other regions. Therefore, the proposed method selects the
vertex, which has a larger curvature value than the threshold value. However, because
selected vertexes are unable to reflect detail components of an original ECG signal, we were
required to supplement the vertexes using the IRM. Fig. 2 represents the block diagram of the
proposed method.
A. Vertex Selection Based on Curvature-
The proposed method calculates the curvature value of the input ECG signal for
vertex selection. Curvature refers to the deviation rate of a curve or the curved surface from a
straight line or plane surface tangent to it [15]. Curve function based on a time variable t is
represented as
O(t) = (S(t),V(t)) (1)
Where s(t) is a sample index at t and v(t) is a signal voltage. A typical ECG signal
contains 60 Hz power line noise, baseline wander, muscle noise, and so on. Therefore, an
accurate ECG compression we get after performing following algorithm.
C(t,σ) = (S(t, σ), V (t, σ)) (2)
Where S(t, σ) = S(t) g(t, σ) (3)
And g(t,σ) =1/(2π)^1/2exp(-t^2/2σ^2) (4)
where g(t, σ) is a Gaussian function for smoothing with the standard deviation σ. Curvature
k(t, σ) based on smoothed signal
C (t, σ) is calculated by
(5)
International Journal of Electronics and Communication Engineering & Technology (IJECET),
ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME
180
The selection process of vertexes consists of the following five steps:
Step 1: The original ECG signal is pre-processed by band pass filtering with 0.5to 25 Hz.
Step 2: A Gaussian LPF is used to eliminate the high frequency noise in pre-processed ECG
signal. The larger standard deviation σ is adopted, and a smoother signal is generated. The
smaller σ causes over-detection of local extrema kloe.
Step 3: R wave is detected by local extrema kloe, which is located at the maximum voltage.
Step 4: Curvature is calculated at all of vertexes by (6).
Step 5: Final vertex is selected by curvature value threshold. After performing above steps
the noise eliminated ECG signal C (t). Vertexes are, marked as ‘O’ and ‘X’ are the top five
points of local maxima, and the bottom six points of local minima, respectively Then we
restored ECG signal based on selected vertexes. However, the restored ECG signal is needed
to supplement vertexes because it has over-distortion with the original ECG signal.
International Journal of Electronics and Communication Engineering & Technology (IJECET),
ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME
181
B. Supplemental Vertex Selection
The initial points for vertex supplement are two adjacent vertexes. Supplemental vertexes
are selected at the point which is larger than DMAX, where d means the vertical distance
between the initial point’s line and vertex.
T=(t1,t2, t3…tc…tn) (6)
where tx is the time axis and N is the number of the axis between A and B. The voltage of the
vertexes is determined by
V=(v1,v2,v3…vc…vtn) (7)
Distance d is expressed as
(8)
where A(ta, va) and B(tb, vb) are vertexes selected from the previous process, and
C(tc, vc) is the candidate of the supplemental vertex. The selection process of the
supplemental vertexes is as follows.
Step 1: Initial vertexes with larger curvature are selected (as stated in subsection II.A).
Step 2: Select the distance value dm between the initial vertexes A and B.
Step 3: Supplemental vertexes are selected by the condition of dmax > Dth
Step 4: Selected supplemental vertexes are connected to the initial vertexes as a line for the
restored signal. Rsp is the restored signal that used not only the initial vertexes but also the
supplemental vertexes.
In above process, Dth is set by the condition of that percent of root mean square
difference (as stated in Section III) is under 9% [17]. And by the experimental result, in the
case of Dth is 0.017, the condition is satisfied. Thus, the higher Dth is set, the larger error rate
of the restored signal is recorded.
The important components of the ECG signal such as P, Q, R, S, and T waves and P-
start, P-end, QRS-start, QRS-end, T-start, and T-end points are preserved effectively.
The compressed points rate (CPR) is used for measurement of compression rate and
restore error. CPR based on the number of vertexes is expressed as
CPR = LC (t)/ LR (t) (9)
Where LC(t) and LR(t) are the number of vertexes in the preprocessed and compressed ECG
signal, respectively.
III. EXPERIMENTAL RESULTS
This method verifies the effectiveness of the database. The database has a 360 Hz
sampling frequency and it is acquired for 1800 sec. The ECG signal is sampled within a
period of 0.0028 sec.
International Journal of Electronics and Communication Engineering & Technology (IJECET),
ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME
182
(a)
(b)
(c)
Fig.3 Experimental Steps for compression of ECG signal by using proposed method
Fig. 3(a) is preprocessed ECG signal. The original signal is filtered with the help of
band pass filter to reduce the ECG signal noise. The high frequency noise is eliminated by a
Gaussian low pass filter, which provides smoothed ECG signal. Fig. 3(b) shows the curvature
value of the vertexes in fig.3 (a).Fig3. (c) Is selected vertexes based on the curvature value in
International Journal of Electronics and Communication Engineering & Technology (IJECET),
ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME
183
fig. 3 (b). With the help of these selected points we can restore the samples of ECG signal.
Further part of the results of ECG signal compression is in process.
In this paper, the compressed points are (CPR) is used for measurement of
compression rate and restore error. CPR based on the number of vertexes is expressed as
CPR= the number of vertexes in processed / number of vertexes is compressed.
IV. CONCLUSION
The ECG signal has important components for diagnosis, such as P wave, QRS-
complex, and S wave. In this paper, the novel compression method of ECG signal is proposed
for effective telecommunication in WPAN. First, the proposed method selects the vertexes
based on curvature value. However, selected vertexes are not suitable to minimize the restore
error. Therefore, supplemental vertexes are selected by the IRM. Through the experimental
results, the proposed method provides both a higher compression performance and less
distortion of the restored signal than AZTEC. The proposed method is able to improve the
effectiveness of telecommunication in WPAN because of its robust compression
performance.
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[4] B. Schijvennaars, G. V. Herpen, and J. A. Kors, “Intraindividual variability in
electrocardiograms,” J. Electrocardiology, vol. 41, pp. 190–196, 2008.
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compression and classification algorithm with quad level vector for ECG holter
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[6] W. C. Mueller, “Arrhythmia detection program for an ambulatory ECG monitor,”
Biomed. Sci. Instrum., vol. 14, pp. 81–85, 1978.
[7] J. R. Cox, F. M. Nolle, H. A. Fozzard, and G. C. Oliver Jr., “AZTEC, a preprocessing
program for real time ECG rhythm analysis,” IEEE Trans. Biomed. Eng., vol. BME-15,
pp. 128–129, 1968.
[8] J. Abenstein and W. Tompkins, “A new data-reduction algorithm for realtime ECG
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[10] A. Djohan, T. Q. Nguyen, and W. J. Tompkins, “ECG compression using discrete
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184
[13] Q. Zhang, A. I. Manriquez, C. Medigue, Y. Papelier, and M. Sorine, “An algorithm for
robust and efficient location of T-wave ends in electrocardiograms,” IEEE Trans.
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[15] B. Yun, S. Lee, J. Cho, J. Choi, and H. Kang, “A new vertex selection scheme using
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  • 1. International Journal of Electronics and Communication Engineering & Technology (IJECET), ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME 177 REAL TIME ECG SIGNAL ANALYSIS BY USING NEW DATA REDUCTION ALGORITHM FOR DIAGNOSIS OVER WPAN Bhuvaneshwari R. Yadwade Dr. S.B.Patil Dept of E & Tc Head of Electronics & Telecommunication Dept. Dr.J.J.Magdum College of engg. Dr. J.J.Magdum College of engg. Jaisingpur, Maharashtra, India Jaisingpur, Maharashtra,India Mr. B.S.Patil Mr. A. R. Chivate Head of Information Technology Dept. of Digital Electronics PVPIT, Budhgaon B.V. B college of engg. & Technology, Hubali Maharashtra, India Karnataka, India ABSTRACT A method to compress diagnostic information without losing data is required to store and transmit them efficiently on a wireless personal area network (WPAN). An ECG contains diagnostic information related to cardiac activity. As electrocardiogram (ECG) signals are generally sampled with a frequency of over 200 Hz, an ECG signal compression method for communications on WPAN, which uses feature points based on curvature, is proposed. The feature points of P, Q, R, S, and T waves, which are critical components of the ECG signal, have large curvature values compared to other vertexes. Thus, these vertexes were extracted with the proposed method, which uses local extrema of curvatures. Furthermore, in order to minimize reconstruction errors of the ECG signal, extra vertexes were added according to the iterative vertex selection method. It was concluded that the vertexes selected by the proposed method preserved all feature points of the ECG signals. Keywords: Curvature, electrocardiogram (ECG), feature extraction, vertex. I. INTRODUCTION Extensive ECG signal data is not suitable for wireless personal area networks (WPAN), because healthcare monitoring system requires a real-time process [1] – [5]. Electrocardiogram (ECG) represents cardiac electrical activity by a graph that contains pre- diagnosis information of various cardiac diseases. ECG signal measures very large amounts INTERNATIONAL JOURNAL OF ELECTRONICS AND COMMUNICATION ENGINEERING & TECHNOLOGY (IJECET) ISSN 0976 – 6464(Print) ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June, 2013, pp. 177-184 © IAEME: www.iaeme.com/ijecet.asp Journal Impact Factor (2013): 5.8896 (Calculated by GISI) www.jifactor.com IJECET © I A E M E
  • 2. International Journal of Electronics and Communication Engineering & Technology (IJECET), ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME 178 of data in a short period of time, because it typically has a higher than 200 Hz sampling frequency. In order to telecommunicate the extensive ECG signal on WPAN, it is needed to compress the signal without loss of significant information for diagnosis. However, compression distortion is able to cause misdiagnosis of healthcare monitoring system. Therefore, the main features of the diagnostic value should be maintained within the tolerance range. Conventional ECG compression research contains the direct compression method, transformational compression method and so on. In order to delineate the accurate description of ECG signal, a variety of approaches, such as those based on numerical differentiation, pattern recognition, and mathematical models have been proposed. The direct compression method detects the redundancy of an ECG signal and eliminates it in the time-domain. This approach contains a turning point (TP) [6], amplitude-zone-time epoch coding (AZTEC) [7]; coordinate reduction time encoding system (CORTES) [8], differential pulse code modulation (DPCM) [9], and etc. The conversion compression method is based on spectrum analysis and energy distribution analysis, which provide the detection of redundancy. Fourier transform, Walsh transformation, wavelet transform, and Karhunen-Loeve transform are conventional conversion compression methods [10]–[12]. The conventional ECG compression method is able to generate distortion of important ECG components, such as P, Q, R, S, and T waves [13], [14]. On the other hand, this paper proposes a P, Q, R, S, and T wave preserving compression method based on local extrema of curvature. Also, the proposed method supplements the vertexes using the iterative refinement method (IRM) to improve peak signal to noise ratio (PSNR) in the compressed ECG signal. Experimental results using the Massachusetts Institute of Technology-Beth Israel hospital (MIT-BIH) arrhythmia database verify the superiority of proposed method.
  • 3. International Journal of Electronics and Communication Engineering & Technology (IJECET), ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME 179 This paper is described by the following contents. The proposed method, which is based on curvature, is explained in Section II. Then, section III provides the experimental results of the proposed method, and section IV makes the conclusion of this paper. II. ECG SIGNAL COMPRESSION USING CURVATURE A typical ECG signal has a P wave, QRS-complex, and T wave, all of which are important component of a diagnosis (see Fig. 1). The start and end points of P, Q, R, S, and T waves are important feature points for diagnosis of heart disease. These feature points have a larger signal variation rate than other regions. Therefore, the proposed method selects the vertex, which has a larger curvature value than the threshold value. However, because selected vertexes are unable to reflect detail components of an original ECG signal, we were required to supplement the vertexes using the IRM. Fig. 2 represents the block diagram of the proposed method. A. Vertex Selection Based on Curvature- The proposed method calculates the curvature value of the input ECG signal for vertex selection. Curvature refers to the deviation rate of a curve or the curved surface from a straight line or plane surface tangent to it [15]. Curve function based on a time variable t is represented as O(t) = (S(t),V(t)) (1) Where s(t) is a sample index at t and v(t) is a signal voltage. A typical ECG signal contains 60 Hz power line noise, baseline wander, muscle noise, and so on. Therefore, an accurate ECG compression we get after performing following algorithm. C(t,σ) = (S(t, σ), V (t, σ)) (2) Where S(t, σ) = S(t) g(t, σ) (3) And g(t,σ) =1/(2π)^1/2exp(-t^2/2σ^2) (4) where g(t, σ) is a Gaussian function for smoothing with the standard deviation σ. Curvature k(t, σ) based on smoothed signal C (t, σ) is calculated by (5)
  • 4. International Journal of Electronics and Communication Engineering & Technology (IJECET), ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME 180 The selection process of vertexes consists of the following five steps: Step 1: The original ECG signal is pre-processed by band pass filtering with 0.5to 25 Hz. Step 2: A Gaussian LPF is used to eliminate the high frequency noise in pre-processed ECG signal. The larger standard deviation σ is adopted, and a smoother signal is generated. The smaller σ causes over-detection of local extrema kloe. Step 3: R wave is detected by local extrema kloe, which is located at the maximum voltage. Step 4: Curvature is calculated at all of vertexes by (6). Step 5: Final vertex is selected by curvature value threshold. After performing above steps the noise eliminated ECG signal C (t). Vertexes are, marked as ‘O’ and ‘X’ are the top five points of local maxima, and the bottom six points of local minima, respectively Then we restored ECG signal based on selected vertexes. However, the restored ECG signal is needed to supplement vertexes because it has over-distortion with the original ECG signal.
  • 5. International Journal of Electronics and Communication Engineering & Technology (IJECET), ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME 181 B. Supplemental Vertex Selection The initial points for vertex supplement are two adjacent vertexes. Supplemental vertexes are selected at the point which is larger than DMAX, where d means the vertical distance between the initial point’s line and vertex. T=(t1,t2, t3…tc…tn) (6) where tx is the time axis and N is the number of the axis between A and B. The voltage of the vertexes is determined by V=(v1,v2,v3…vc…vtn) (7) Distance d is expressed as (8) where A(ta, va) and B(tb, vb) are vertexes selected from the previous process, and C(tc, vc) is the candidate of the supplemental vertex. The selection process of the supplemental vertexes is as follows. Step 1: Initial vertexes with larger curvature are selected (as stated in subsection II.A). Step 2: Select the distance value dm between the initial vertexes A and B. Step 3: Supplemental vertexes are selected by the condition of dmax > Dth Step 4: Selected supplemental vertexes are connected to the initial vertexes as a line for the restored signal. Rsp is the restored signal that used not only the initial vertexes but also the supplemental vertexes. In above process, Dth is set by the condition of that percent of root mean square difference (as stated in Section III) is under 9% [17]. And by the experimental result, in the case of Dth is 0.017, the condition is satisfied. Thus, the higher Dth is set, the larger error rate of the restored signal is recorded. The important components of the ECG signal such as P, Q, R, S, and T waves and P- start, P-end, QRS-start, QRS-end, T-start, and T-end points are preserved effectively. The compressed points rate (CPR) is used for measurement of compression rate and restore error. CPR based on the number of vertexes is expressed as CPR = LC (t)/ LR (t) (9) Where LC(t) and LR(t) are the number of vertexes in the preprocessed and compressed ECG signal, respectively. III. EXPERIMENTAL RESULTS This method verifies the effectiveness of the database. The database has a 360 Hz sampling frequency and it is acquired for 1800 sec. The ECG signal is sampled within a period of 0.0028 sec.
  • 6. International Journal of Electronics and Communication Engineering & Technology (IJECET), ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME 182 (a) (b) (c) Fig.3 Experimental Steps for compression of ECG signal by using proposed method Fig. 3(a) is preprocessed ECG signal. The original signal is filtered with the help of band pass filter to reduce the ECG signal noise. The high frequency noise is eliminated by a Gaussian low pass filter, which provides smoothed ECG signal. Fig. 3(b) shows the curvature value of the vertexes in fig.3 (a).Fig3. (c) Is selected vertexes based on the curvature value in
  • 7. International Journal of Electronics and Communication Engineering & Technology (IJECET), ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME 183 fig. 3 (b). With the help of these selected points we can restore the samples of ECG signal. Further part of the results of ECG signal compression is in process. In this paper, the compressed points are (CPR) is used for measurement of compression rate and restore error. CPR based on the number of vertexes is expressed as CPR= the number of vertexes in processed / number of vertexes is compressed. IV. CONCLUSION The ECG signal has important components for diagnosis, such as P wave, QRS- complex, and S wave. In this paper, the novel compression method of ECG signal is proposed for effective telecommunication in WPAN. First, the proposed method selects the vertexes based on curvature value. However, selected vertexes are not suitable to minimize the restore error. Therefore, supplemental vertexes are selected by the IRM. Through the experimental results, the proposed method provides both a higher compression performance and less distortion of the restored signal than AZTEC. The proposed method is able to improve the effectiveness of telecommunication in WPAN because of its robust compression performance. REFERENCES [1] F. Enseleit and F. Duru, “Long-term continuous external electrocardiographic recording: A review,” Europace, vol. 8, pp. 255–266, 2006. [2] Q. Ling , Z. Tian, and Y. Li, “Distributed decision-making in wireless sensor networks for online structural health monitoring,” J. Commun. Netw., vol. 11, pp. 350–358, 2009. [3] C. K. Yeo, I. Y. Soon, and C. T. Lau, “Lossless compression of multispectral satellite images,” J. Commun. Netw., vol. 1, pp. 226–230, 1999. [4] B. Schijvennaars, G. V. Herpen, and J. A. Kors, “Intraindividual variability in electrocardiograms,” J. Electrocardiology, vol. 41, pp. 190–196, 2008. [5] H. Kim, R. F. Yazicioglu, P. Merken, C. V. Hoof, and H. Yoo, “ECG signal compression and classification algorithm with quad level vector for ECG holter system,” IEEE Trans. Inf. Technol. Biomed., vol. 14, pp. 93–100, 2010. [6] W. C. Mueller, “Arrhythmia detection program for an ambulatory ECG monitor,” Biomed. Sci. Instrum., vol. 14, pp. 81–85, 1978. [7] J. R. Cox, F. M. Nolle, H. A. Fozzard, and G. C. Oliver Jr., “AZTEC, a preprocessing program for real time ECG rhythm analysis,” IEEE Trans. Biomed. Eng., vol. BME-15, pp. 128–129, 1968. [8] J. Abenstein and W. Tompkins, “A new data-reduction algorithm for realtime ECG analysis,” IEEE Trans. Biomed. Eng., vol. BME-29, pp. 43–48, 1982. [9] U. E. Ruttimann and H. V. Pipberger, “Compression of the ECG by prediction or interpolation and entropy encoding,” IEEE Trans. Biomed. Eng., vol. BEM-26, pp. 613–623, 1979. [10] A. Djohan, T. Q. Nguyen, and W. J. Tompkins, “ECG compression using discrete symmetricwavelet transform,” in Proc. IEEE EMBC., vol. 1, 1995, pp. 167–168. [11] M. L. Hilton, “Wavelet and wavelet packet compression of electrocardiograms,” IEEE Trans. Biomed. Eng., vol. 44, pp. 394–402, 1997. [12] J. Martinez, R. Almeida, S. Olmos, A. P. Rocha, and P. Laguna, “A wavelet-based ECG delineator: Evaluation on standard databases,” IEEE Trans. Biomed. Eng., vol. 51, pp. 570–581, 2004.
  • 8. International Journal of Electronics and Communication Engineering & Technology (IJECET), ISSN 0976 – 6464(Print), ISSN 0976 – 6472(Online) Volume 4, Issue 3, May – June (2013), © IAEME 184 [13] Q. Zhang, A. I. Manriquez, C. Medigue, Y. Papelier, and M. Sorine, “An algorithm for robust and efficient location of T-wave ends in electrocardiograms,” IEEE Trans. Biomed. Eng., vol. 53, pp. 2544–2552, 2006. [14] M. Benmalek and A. Charef, “Digital fractional order operators for R wave detection in electrocardiogram signal,” IET Signal Process., vol. 3, pp. 381–391, 2009. [15] B. Yun, S. Lee, J. Cho, J. Choi, and H. Kang, “A new vertex selection scheme using curvature information,” Lecture Note in Artificial Intelligence, vol. 3215, pp. 887–893, 2004. [16] A. A. Iglesias and J. G.Moros, “Automatic real time ECG coding methodology guaranteeing signal interpretation quality,” IEEE Trans. Biomed. Eng., vol. 55, pp. 2519–2527. 2008. [17] Y. Zigel, A. Cohen, and A. Katz, “The weighted eiagnostic distortion (WDD) measure for ECG signal compression,” IEEE Trans. Biomed. Eng., vol. 27, no. 11, 2000. [18] Kavita L.Awade, “ECG Signal Processing for Detection and Classification of Cardiac Diseases”, International Journal of Electronics and Communication Engineering & Technology (IJECET), Volume 1, Issue 1, 2010, pp. 33 - 43, ISSN Print: 0976- 6464, ISSN Online: 0976 –6472. [19] Samir Elouaham, Rachid Latif, Boujemaa Nassiri, Azzedine Dliou, Mostafa Laaboubi and Fadel Maoulainine, “Analysis Electrocardiogram Signal using Ensemble Empirical Mode Decomposition and Time-Frequency Techniques”, International Journal of Computer Engineering & Technology (IJCET), Volume 4, Issue 2, 2013, pp. 275 - 289, ISSN Print: 0976 – 6367, ISSN Online: 0976 – 6375.