The real number system includes natural numbers, integers, rational numbers, irrational numbers, and real numbers. Natural numbers are the non-negative whole numbers starting at 0. Integers add the negative whole numbers. Rational numbers are numbers that can be represented as fractions of integers. Irrational numbers cannot be represented as fractions. Real numbers include all rational and irrational numbers and can be located on the real number line. The real number system is closed under addition and multiplication and follows important properties like commutativity and associativity.