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For BPH 1st Year
Dr. Pravin Prasad
2nd Year Resident, MD Clinical Pharmacology
Maharajgunj Medical Campus
16th March, 2017 (3rd Chaitra, 2073), Thursday
Background:
choosing treatment
options
Rational Use of Drugs
(Medicines)◦Requires that patients receive
medications:
◦Appropriate to their clinical needs,
◦In doses that meet their own
individual requirements,
◦For an adequate period of time, and
◦At the lowest cost to them and their
community.
WHO conference of experts Nairobi
1985
So, what would you understand by Irrational use of
Medicines?
Rational Use of Drugs
(Medicines)
◦Right Patient
◦Right Drug
◦Right Amount
◦Right
Indication
◦Right Time
◦Right
Information
Why Rational Use is
Important?
◦Irrational Use has various harms.
Ineffective & unsafe treatment
Increased morbidity (Adverse Drug Events,
prolonged illness) and mortality
Why Rational Use is
Important?
◦Irrational Use has various harms.
Increased drug resistance
Distress, harm and cost burden to patient and
community as a whole
Why used
irrationally??
◦Lack of information
◦Role models – Teachers or seniors
◦Lack of diagnostic
facilities/Uncertainty of diagnosis –
medicine for all possible causes
◦Demand from the patient
Why used
irrationally??◦Patient load
◦Promotional activities of
pharmaceutical industries
◦Drug promotion and exaggerated
claim by companies
◦Defective drug supply system &
ineffective drug regulation
Irrational Use: Few
examples
◦Injudicious use of antimicrobials
◦Unnecessary combinations
◦Use of drugs not related to
diagnosis
◦Incorrect route, dosing or duration
◦Unnecessary use of expensive
medicines
◦Unsafe use of corticosteroids
◦Polypharmacy
Moving towards
Rational Use…
Educational Strategies
Training for Providers
Undergraduate education
Continuing in-service medical education
(seminars, workshops)
Face-to-face persuasive outreach e.g.
academic detailing
Clinical supervision or consultation
Educational Strategies
Printed Materials
Clinical literature and newsletters
Formularies or therapeutics manuals
Persuasive print materials
Educational Strategies
Media-Based Approaches
Posters
Audio tapes, plays
Radio, television
Managerial Strategies
Changes in selection, procurement,
distribution to ensure availability of
essential drugs
Essential Drug Lists
Morbidity based quantification
Kit system
Managerial Strategies
Strategies aimed at prescribers
Targeted face-to-face supervision with audit
Peer group monitoring
Structured order forms
Evidence-based standard treatment
Managerial Strategies
Dispensing strategies
Course of treatment packaging
Labelling
Generic substitution
Economic Strategies
Avoid perverse financial incentives
Prescribers’ salaries from drug sales
Insurance policies that reimburse non-
essential drugs or incorrect doses
Flat prescription fees
Regulatory Strategies
Drug registration
Banning of unsafe drugs
Regulating the use of different drugs to
different levels of health sector
Regulating pharmaceutical promotional
activities
Rational Prescribing
Define Patient’s
Problem
Set Therapeutic
Objectives
Select Therapeutic
Strategies
Prescription Writing
Giving Information,
instructions,
warnings
Monitoring
Treatment
That will be all for today!!
◦Any Queries?
◦Thank you!

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Rational use of medicines for BPH

Editor's Notes

  1. Appropriate indication Appropriate drug considering efficacy, safety, suitability for the patient, and cost appropriate dosage, administration, duration no contraindications correct dispensing, including appropriate information for patients patient adherence to treatment
  2. Appropriate indication Appropriate drug considering efficacy, safety, suitability for the patient, and cost appropriate dosage, administration, duration no contraindications correct dispensing, including appropriate information for patients patient adherence to treatment
  3. Ineffective & unsafe treatment over-treatment of mild illness inadequate treatment of serious illness
  4. Ineffective & unsafe treatment over-treatment of mild illness inadequate treatment of serious illness