Radiotherapy uses high-dose radiation to kill cancer cells. It can be delivered externally using machines like linear accelerators, or internally by implanting radioactive materials near tumors. External radiotherapy does not require safety precautions after treatment, while internal radiotherapy emits radiation and requires precautions like minimizing contact time and using shielding. Radiotherapy can cause both acute side effects like nausea and late effects like fibrosis, so safety is important for healthcare workers providing care to these patients.