Pyogenic meningitis
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This document discusses pyogenic meningitis, an infection of the meninges caused by bacteria such as Neisseria meningitidis and Streptococcus pneumoniae. It describes the pathogenesis of the disease, including how bacteria colonize the nasopharynx, breach the mucosa and enter the cerebrospinal fluid and meninges. It notes that the bacteria can proliferate and cause inflammation in the subarachnoid space and ventricles. The document also includes images from MRI scans that demonstrate meningeal enhancement and lesions associated with different types of meningitis.
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Pyogenic meningitis
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- 13. bacterial colonization of nasopharynx attach to mucosal epith. cell receptors by pili breach mucosa& enter circulation to CSF thru choroid plexus of ventricles extracerebral CSF & subarachinoid space bacterial proliferation inflammation-cytokines large capsules interfere phagocytosis
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- 15. Pathogenesis of Meningococcal Infections
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- 21. fulminant meningococcemia with extensive purpuric patches.
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- 26. Axial T1 C+ MR shows extensive leptomeningeal enhancement of the sulci & cisterns (arrows) in this patient with Streptococcus pneumoniae meningitis.
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- 28. (Left) Axial T1 C+ MR shows diffuse, basilar enhancement with tb meningitis. The basal predominance can help differentiate TB from other causes of meningitis (Right) Axial T1 C+ MR shows homogeneous, nodular enhancement typical of noncaseating tuberculoma (arrow), peripheral rim enhancement with central necrosis typical of a caseating tuberculoma (open arrow).
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